Danio rerio

0 known processes

grin2ab

glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b

(Aliases: im:7137621,si:dkey-20i6.1)

grin2ab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.087
maintenance of location GO:0051235 4 0.061
positive regulation of transport GO:0051050 2 0.042
signal transduction GO:0007165 455 0.040
Mouse Rat
aging GO:0007568 2 0.039
generation of neurons GO:0048699 385 0.038
neuron neuron synaptic transmission GO:0007270 1 0.037
embryonic organ development GO:0048568 381 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.035
Mouse
brain development GO:0007420 293 0.034
Rat
cellular component morphogenesis GO:0032989 336 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
Mouse
regulation of gene expression GO:0010468 265 0.034
single organism metabolic process GO:0044710 217 0.034
negative regulation of protein kinase activity GO:0006469 4 0.033
regulation of metabolic process GO:0019222 359 0.033
Mouse
central nervous system development GO:0007417 387 0.033
Rat
cytokinesis GO:0000910 3 0.032
heterocycle metabolic process GO:0046483 290 0.032
Mouse
neurotransmitter secretion GO:0007269 2 0.031
tube morphogenesis GO:0035239 349 0.031
positive regulation of cell cycle GO:0045787 3 0.031
cellular amine metabolic process GO:0044106 2 0.030
phagocytosis GO:0006909 3 0.029
regulation of response to stimulus GO:0048583 269 0.029
sensory organ development GO:0007423 393 0.029
amine metabolic process GO:0009308 2 0.029
camera type eye development GO:0043010 222 0.029
locomotion GO:0040011 313 0.029
Mouse
neuron development GO:0048666 262 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.028
neuron differentiation GO:0030182 353 0.028
meiotic nuclear division GO:0007126 4 0.027
cellular ketone metabolic process GO:0042180 11 0.027
lipid storage GO:0019915 1 0.027
regulation of reproductive process GO:2000241 4 0.027
cellular component assembly GO:0022607 170 0.027
Rat
cellular macromolecule metabolic process GO:0044260 391 0.027
morphogenesis of an epithelium GO:0002009 333 0.027
transcription dna templated GO:0006351 181 0.027
head development GO:0060322 303 0.027
Rat
small molecule metabolic process GO:0044281 77 0.026
retina development in camera type eye GO:0060041 146 0.026
response to external stimulus GO:0009605 264 0.026
Mouse Rat
cell surface receptor signaling pathway GO:0007166 325 0.026
Mouse Rat
gene expression GO:0010467 252 0.026
multicellular organism growth GO:0035264 4 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
Mouse
embryonic organ morphogenesis GO:0048562 274 0.025
synaptic vesicle localization GO:0097479 1 0.025
regulation of cell activation GO:0050865 1 0.025
stem cell maintenance GO:0019827 4 0.024
regulation of biological quality GO:0065008 263 0.024
Mouse Rat
digestive tract development GO:0048565 265 0.024
stem cell proliferation GO:0072089 4 0.024
positive regulation of catabolic process GO:0009896 4 0.023
adult behavior GO:0030534 2 0.023
neurotransmitter transport GO:0006836 2 0.023
regulation of protein transport GO:0051223 3 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
response to stress GO:0006950 263 0.023
Mouse
rna biosynthetic process GO:0032774 181 0.023
nucleic acid templated transcription GO:0097659 181 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cell part morphogenesis GO:0032990 246 0.023
system process GO:0003008 185 0.023
Mouse Rat
regulation of multicellular organism growth GO:0040014 4 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of cell communication GO:0010646 232 0.022
Mouse Rat
nucleobase containing compound metabolic process GO:0006139 274 0.022
cellular response to light stimulus GO:0071482 4 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
regulation of protein complex assembly GO:0043254 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
gtp catabolic process GO:0006184 2 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
organic acid metabolic process GO:0006082 31 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
Mouse
single organism organelle organization GO:1902589 199 0.021
synaptic vesicle transport GO:0048489 1 0.021
regulation of binding GO:0051098 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
eye development GO:0001654 277 0.021
organic substance biosynthetic process GO:1901576 289 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
Mouse
nucleic acid metabolic process GO:0090304 244 0.021
regulation of metal ion transport GO:0010959 4 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
single organism localization GO:1902578 225 0.020
Mouse Rat
regulation of signaling GO:0023051 235 0.020
Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 7 0.020
cell morphogenesis GO:0000902 289 0.020
establishment of localization GO:0051234 244 0.020
Mouse Rat
regulation of signal transduction GO:0009966 225 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
immune system process GO:0002376 241 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
chemosensory behavior GO:0007635 1 0.019
nuclear transport GO:0051169 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
cell projection organization GO:0030030 284 0.019
negative regulation of cellular process GO:0048523 283 0.019
membrane invagination GO:0010324 1 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
Mouse
regulation of transcription dna templated GO:0006355 213 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
biosynthetic process GO:0009058 294 0.019
positive regulation of biological process GO:0048518 253 0.019
Mouse Rat
phosphate containing compound metabolic process GO:0006796 108 0.019
negative regulation of neural precursor cell proliferation GO:2000178 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of synapse assembly GO:0051963 3 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
establishment of synaptic vesicle localization GO:0097480 1 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
protein targeting to nucleus GO:0044744 3 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
regulation of circadian rhythm GO:0042752 4 0.018
neuroblast proliferation GO:0007405 2 0.018
positive regulation of cellular process GO:0048522 201 0.018
Mouse Rat
nuclear import GO:0051170 3 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
rna metabolic process GO:0016070 219 0.018
protein localization to nucleus GO:0034504 3 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
transmembrane transport GO:0055085 120 0.018
Mouse Rat
regulation of neurotransmitter transport GO:0051588 1 0.018
ear development GO:0043583 127 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
response to chemical GO:0042221 320 0.018
Human Mouse Rat
protein acylation GO:0043543 3 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
response to drug GO:0042493 3 0.017
Mouse Rat
negative regulation of kinase activity GO:0033673 4 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cognition GO:0050890 1 0.017
Mouse Rat
digestive system development GO:0055123 289 0.017
gtp metabolic process GO:0046039 4 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
negative regulation of biological process GO:0048519 304 0.017
Mouse
vasculature development GO:0001944 278 0.017
transport GO:0006810 220 0.017
Mouse Rat
single organism nuclear import GO:1902593 3 0.017
protein localization to plasma membrane GO:0072659 1 0.017
protein import GO:0017038 3 0.017
regulation of primary metabolic process GO:0080090 311 0.017
Mouse
proteasomal protein catabolic process GO:0010498 2 0.017
sensory organ morphogenesis GO:0090596 200 0.016
protein metabolic process GO:0019538 183 0.016
Mouse
sequestering of calcium ion GO:0051208 3 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
spermatid differentiation GO:0048515 2 0.016
cellular response to radiation GO:0071478 4 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
axonogenesis GO:0007409 152 0.016
cellular component movement GO:0006928 335 0.016
regulation of developmental process GO:0050793 247 0.016
phagocytosis engulfment GO:0006911 1 0.016
digestive tract morphogenesis GO:0048546 231 0.016
protein polymerization GO:0051258 4 0.016
regulation of synapse organization GO:0050807 3 0.016
spermatid development GO:0007286 2 0.016
organelle organization GO:0006996 227 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
eye morphogenesis GO:0048592 144 0.016
regulation of inflammatory response GO:0050727 2 0.016
g protein coupled receptor signaling pathway GO:0007186 74 0.016
meiotic cell cycle process GO:1903046 3 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
regulation of rna biosynthetic process GO:2001141 213 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
regulation of biosynthetic process GO:0009889 250 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
cellular component biogenesis GO:0044085 178 0.015
Rat
protein import into nucleus GO:0006606 3 0.015
response to external biotic stimulus GO:0043207 97 0.015
Rat
post embryonic organ development GO:0048569 4 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of rna metabolic process GO:0051252 224 0.015
cell migration GO:0016477 237 0.015
regulation of autophagy GO:0010506 3 0.015
response to abiotic stimulus GO:0009628 122 0.015
Mouse Rat
endosomal transport GO:0016197 2 0.015
cellular protein metabolic process GO:0044267 129 0.015
localization of cell GO:0051674 244 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
sequestering of metal ion GO:0051238 3 0.015
cellular amide metabolic process GO:0043603 4 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
response to other organism GO:0051707 97 0.014
Rat
immune system development GO:0002520 191 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
growth GO:0040007 174 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of cell development GO:0060284 100 0.014
neuron projection morphogenesis GO:0048812 161 0.014
regionalization GO:0003002 274 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
response to carbohydrate GO:0009743 3 0.014
Rat
cellular response to external stimulus GO:0071496 2 0.014
regulation of localization GO:0032879 104 0.014
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of transporter activity GO:0032409 2 0.014
mitochondrion organization GO:0007005 4 0.014
cellular biosynthetic process GO:0044249 286 0.014
chordate embryonic development GO:0043009 271 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
regulation of multicellular organismal process GO:0051239 277 0.013
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
antimicrobial humoral response GO:0019730 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
gastrulation GO:0007369 208 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
positive regulation of reproductive process GO:2000243 2 0.013
protein acetylation GO:0006473 2 0.013
cellular component disassembly GO:0022411 1 0.013
locomotor rhythm GO:0045475 3 0.013
female gonad development GO:0008585 4 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
response to monosaccharide GO:0034284 3 0.013
skeletal system development GO:0001501 181 0.013
negative regulation of defense response GO:0031348 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
phototransduction GO:0007602 2 0.013
response to hexose GO:0009746 3 0.013
pole plasm assembly GO:0007315 4 0.013
autophagy GO:0006914 4 0.013
adherens junction organization GO:0034332 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
determination of left right symmetry GO:0007368 179 0.013
cell motility GO:0048870 244 0.013
blood vessel development GO:0001568 246 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
mononuclear cell proliferation GO:0032943 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.012
regulation of blood pressure GO:0008217 1 0.012
urogenital system development GO:0001655 97 0.012
axon development GO:0061564 166 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
leukocyte proliferation GO:0070661 1 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
muscle structure development GO:0061061 196 0.012
heart development GO:0007507 313 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
angiogenesis GO:0001525 158 0.012
actin filament polymerization GO:0030041 2 0.012
circulatory system process GO:0003013 87 0.012
b cell activation GO:0042113 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
blood vessel morphogenesis GO:0048514 216 0.012
response to wounding GO:0009611 116 0.012
Mouse
regulation of cell projection assembly GO:0060491 4 0.012
lateral line system development GO:0048925 76 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
single fertilization GO:0007338 3 0.012
regulation of calcium ion transport GO:0051924 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Rat
rna localization GO:0006403 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
small molecule catabolic process GO:0044282 3 0.012
multi organism process GO:0051704 134 0.012
Rat
developmental growth GO:0048589 166 0.012
hormone secretion GO:0046879 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
Mouse
regulation of cell differentiation GO:0045595 142 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
photoreceptor cell development GO:0042461 40 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
cellular response to organic substance GO:0071310 105 0.011
Rat
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
sympathetic nervous system development GO:0048485 3 0.011
regulation of cytokine production GO:0001817 3 0.011
compound eye development GO:0048749 2 0.011
regulation of cell shape GO:0008360 1 0.011
specification of symmetry GO:0009799 204 0.011
cytoskeleton organization GO:0007010 96 0.011
response to glucose GO:0009749 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
hindbrain development GO:0030902 91 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
photoreceptor cell differentiation GO:0046530 55 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
Mouse Rat
regulation of dna replication GO:0006275 3 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
secondary metabolic process GO:0019748 3 0.011
protein secretion GO:0009306 1 0.011
regulation of sodium ion transport GO:0002028 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
renal system development GO:0072001 94 0.011
regulation of protein catabolic process GO:0042176 1 0.011
Mouse
cortical cytoskeleton organization GO:0030865 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
neuron projection development GO:0031175 180 0.011
cell substrate adhesion GO:0031589 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
pectoral fin development GO:0033339 50 0.011
regulation of gtpase activity GO:0043087 2 0.011
macromolecule modification GO:0043412 111 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
protein stabilization GO:0050821 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
determination of bilateral symmetry GO:0009855 204 0.011
protein modification process GO:0036211 100 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
cellular response to oxygen levels GO:0071453 1 0.011
regulation of nervous system development GO:0051960 90 0.011
intracellular signal transduction GO:0035556 85 0.011
exocytosis GO:0006887 1 0.011
response to uv GO:0009411 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
programmed cell death GO:0012501 119 0.010
Mouse
neural retina development GO:0003407 49 0.010
negative regulation of gene expression GO:0010629 65 0.010
regulation of skeletal muscle tissue development GO:0048641 4 0.010
protein complex disassembly GO:0043241 1 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
defense response GO:0006952 47 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
pancreas development GO:0031016 84 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
cell matrix adhesion GO:0007160 4 0.010
regulation of tube size GO:0035150 2 0.010
phototransduction visible light GO:0007603 2 0.010
embryonic skeletal system development GO:0048706 97 0.010
cartilage development GO:0051216 96 0.010
single organism transport GO:0044765 206 0.010
Mouse Rat
response to corticosteroid GO:0031960 1 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of dendrite development GO:0050773 3 0.010
actin cytoskeleton organization GO:0030036 63 0.010

grin2ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
Human
nervous system disease DOID:863 0 0.032
Human
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.011
retinal disease DOID:5679 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010