Danio rerio

0 known processes

sc:d0144

sc:d0144

sc:d0144 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
actin polymerization or depolymerization GO:0008154 2 0.098
negative regulation of protein localization to nucleus GO:1900181 2 0.083
larval development GO:0002164 2 0.081
regulation of macromolecule metabolic process GO:0060255 317 0.081
cytokinetic process GO:0032506 2 0.081
positive regulation of transport GO:0051050 2 0.077
regulation of synapse organization GO:0050807 3 0.076
regulation of cytoplasmic transport GO:1903649 4 0.076
synaptic growth at neuromuscular junction GO:0051124 2 0.075
aging GO:0007568 2 0.073
cytokinesis GO:0000910 3 0.072
regulation of intracellular protein transport GO:0033157 3 0.066
maternal determination of anterior posterior axis embryo GO:0008358 4 0.064
protein metabolic process GO:0019538 183 0.053
response to external biotic stimulus GO:0043207 97 0.053
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.051
regulation of protein import into nucleus GO:0042306 2 0.049
single organism localization GO:1902578 225 0.046
positive regulation of cellular process GO:0048522 201 0.046
regulation of establishment of protein localization GO:0070201 4 0.045
nuclear import GO:0051170 3 0.045
nucleocytoplasmic transport GO:0006913 4 0.045
regulation of nucleocytoplasmic transport GO:0046822 2 0.045
regulation of primary metabolic process GO:0080090 311 0.043
response to external stimulus GO:0009605 264 0.042
single organism nuclear import GO:1902593 3 0.042
negative regulation of response to stimulus GO:0048585 104 0.041
gtp catabolic process GO:0006184 2 0.041
sensory organ development GO:0007423 393 0.040
digestive tract development GO:0048565 265 0.040
response to bacterium GO:0009617 58 0.040
regulation of biological quality GO:0065008 263 0.038
neuron development GO:0048666 262 0.038
biosynthetic process GO:0009058 294 0.038
protein complex localization GO:0031503 1 0.037
cellular biosynthetic process GO:0044249 286 0.037
regulation of synapse assembly GO:0051963 3 0.037
regulation of protein transport GO:0051223 3 0.037
stem cell division GO:0017145 1 0.036
single organism organelle organization GO:1902589 199 0.035
protein import into nucleus GO:0006606 3 0.035
cellular protein catabolic process GO:0044257 4 0.035
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.035
phagocytosis GO:0006909 3 0.034
nuclear transport GO:0051169 4 0.034
regulation of cell activation GO:0050865 1 0.034
cortical cytoskeleton organization GO:0030865 1 0.033
cellular response to biotic stimulus GO:0071216 3 0.033
positive regulation of cell adhesion GO:0045785 1 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.033
epidermis development GO:0008544 48 0.033
ameboidal type cell migration GO:0001667 143 0.033
cellular macromolecule metabolic process GO:0044260 391 0.032
stem cell maintenance GO:0019827 4 0.032
cognition GO:0050890 1 0.032
long chain fatty acid biosynthetic process GO:0042759 1 0.032
amine metabolic process GO:0009308 2 0.032
cellular response to molecule of bacterial origin GO:0071219 3 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
modification dependent protein catabolic process GO:0019941 3 0.031
antimicrobial humoral response GO:0019730 2 0.031
protein polymerization GO:0051258 4 0.030
actin filament polymerization GO:0030041 2 0.030
muscle cell development GO:0055001 115 0.029
signal transduction GO:0007165 455 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
digestive system development GO:0055123 289 0.029
response to chemical GO:0042221 320 0.029
axon extension GO:0048675 45 0.029
protein import GO:0017038 3 0.029
cell migration involved in gastrulation GO:0042074 79 0.029
regulation of protein catabolic process GO:0042176 1 0.028
transport GO:0006810 220 0.028
regulation of epithelial cell proliferation GO:0050678 3 0.028
adherens junction organization GO:0034332 4 0.028
regulation of localization GO:0032879 104 0.028
regionalization GO:0003002 274 0.028
regulation of protein localization to nucleus GO:1900180 2 0.027
stem cell proliferation GO:0072089 4 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
response to stress GO:0006950 263 0.027
regulation of protein complex assembly GO:0043254 3 0.026
leukocyte proliferation GO:0070661 1 0.026
regulation of metabolic process GO:0019222 359 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of wound healing GO:0061041 2 0.025
mononuclear cell proliferation GO:0032943 1 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
positive regulation of metabolic process GO:0009893 108 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
locomotion GO:0040011 313 0.024
protein localization to nucleus GO:0034504 3 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
cell motility GO:0048870 244 0.024
cellular component movement GO:0006928 335 0.024
response to drug GO:0042493 3 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
oocyte anterior posterior axis specification GO:0007314 4 0.024
cell migration GO:0016477 237 0.024
organic acid metabolic process GO:0006082 31 0.023
cell projection organization GO:0030030 284 0.023
digestive tract morphogenesis GO:0048546 231 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
protein targeting to nucleus GO:0044744 3 0.023
maintenance of location GO:0051235 4 0.023
regulation of cell shape GO:0008360 1 0.022
morphogenesis of an epithelial fold GO:0060571 1 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.022
protein localization to plasma membrane GO:0072659 1 0.022
cortical actin cytoskeleton organization GO:0030866 1 0.022
embryonic organ development GO:0048568 381 0.022
regulation of reproductive process GO:2000241 4 0.022
regulation of dendrite development GO:0050773 3 0.022
establishment of localization GO:0051234 244 0.022
nucleic acid templated transcription GO:0097659 181 0.022
dna templated transcription elongation GO:0006354 3 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of chromosome segregation GO:0051983 1 0.021
lipid catabolic process GO:0016042 4 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
stem cell differentiation GO:0048863 117 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
localization of cell GO:0051674 244 0.021
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.021
neurotransmitter transport GO:0006836 2 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.021
lymphocyte proliferation GO:0046651 1 0.021
positive regulation of cell activation GO:0050867 1 0.020
cell death GO:0008219 121 0.020
cellular protein metabolic process GO:0044267 129 0.020
cellular protein complex assembly GO:0043623 19 0.020
multicellular organismal water homeostasis GO:0050891 1 0.020
long chain fatty acid metabolic process GO:0001676 1 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.020
lipid storage GO:0019915 1 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
camera type eye development GO:0043010 222 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
response to radiation GO:0009314 51 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
response to amino acid GO:0043200 2 0.019
eye development GO:0001654 277 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
cellular response to external stimulus GO:0071496 2 0.019
axonogenesis GO:0007409 152 0.019
gtp metabolic process GO:0046039 4 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
intracellular signal transduction GO:0035556 85 0.018
negative regulation of kinase activity GO:0033673 4 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
neurotransmitter secretion GO:0007269 2 0.018
cellular response to nutrient levels GO:0031669 2 0.018
organelle localization GO:0051640 49 0.018
negative regulation of myeloid cell differentiation GO:0045638 1 0.018
germ line stem cell maintenance GO:0030718 2 0.018
dicarboxylic acid transport GO:0006835 1 0.018
interspecies interaction between organisms GO:0044419 4 0.017
cell projection morphogenesis GO:0048858 244 0.017
alpha amino acid metabolic process GO:1901605 3 0.017
macrophage chemotaxis GO:0048246 3 0.017
cellular component morphogenesis GO:0032989 336 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
fertilization GO:0009566 3 0.017
positive regulation of protein polymerization GO:0032273 2 0.017
vasculature development GO:0001944 278 0.017
oxoacid metabolic process GO:0043436 31 0.017
protein dephosphorylation GO:0006470 3 0.017
single organism transport GO:0044765 206 0.017
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of protein polymerization GO:0032271 2 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
multicellular organism growth GO:0035264 4 0.016
axis specification GO:0009798 43 0.016
regulation of gene expression GO:0010468 265 0.016
transcription dna templated GO:0006351 181 0.016
cell morphogenesis GO:0000902 289 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
somatic muscle development GO:0007525 4 0.016
heterocycle metabolic process GO:0046483 290 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
positive regulation of biological process GO:0048518 253 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
chemotaxis GO:0006935 104 0.016
regulation of binding GO:0051098 3 0.015
detection of chemical stimulus GO:0009593 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
growth GO:0040007 174 0.015
striated muscle cell development GO:0055002 108 0.015
positive regulation of endothelial cell proliferation GO:0001938 1 0.015
cellular macromolecule localization GO:0070727 21 0.015
regulation of response to stimulus GO:0048583 269 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
single organism metabolic process GO:0044710 217 0.014
cellular component biogenesis GO:0044085 178 0.014
mediolateral intercalation GO:0060031 3 0.014
system process GO:0003008 185 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
regulation of membrane potential GO:0042391 23 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
generation of neurons GO:0048699 385 0.014
regulation of biosynthetic process GO:0009889 250 0.014
meiotic cell cycle process GO:1903046 3 0.014
regulation of muscle contraction GO:0006937 3 0.014
heart development GO:0007507 313 0.014
regulation of signaling GO:0023051 235 0.014
cellular component maintenance GO:0043954 3 0.014
protein complex disassembly GO:0043241 1 0.014
protein complex assembly GO:0006461 30 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
gastrulation GO:0007369 208 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
regulation of protein targeting GO:1903533 2 0.014
response to inorganic substance GO:0010035 38 0.014
exocytosis GO:0006887 1 0.014
cell matrix adhesion GO:0007160 4 0.013
regulation of immune system process GO:0002682 34 0.013
cell proliferation GO:0008283 80 0.013
specification of symmetry GO:0009799 204 0.013
neuron projection development GO:0031175 180 0.013
neuron differentiation GO:0030182 353 0.013
epithelial cell differentiation GO:0030855 116 0.013
cellular component assembly GO:0022607 170 0.013
single organism membrane fusion GO:0044801 2 0.013
neuron projection extension GO:1990138 45 0.013
nuclear export GO:0051168 1 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of protein metabolic process GO:0051246 56 0.013
regulation of hemostasis GO:1900046 1 0.013
single fertilization GO:0007338 3 0.013
positive regulation of cell cycle GO:0045787 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
segmentation GO:0035282 97 0.013
regulation of signal transduction GO:0009966 225 0.013
endosome organization GO:0007032 2 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
regulation of oocyte development GO:0060281 3 0.012
inner ear development GO:0048839 126 0.012
regulation of cell motility GO:2000145 46 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
response to wounding GO:0009611 116 0.012
response to other organism GO:0051707 97 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of extent of cell growth GO:0061387 29 0.012
axon development GO:0061564 166 0.012
gene expression GO:0010467 252 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
rna localization GO:0006403 4 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
single organism cell adhesion GO:0098602 29 0.012
organelle organization GO:0006996 227 0.012
stem cell development GO:0048864 82 0.012
cellular amide metabolic process GO:0043603 4 0.012
neural crest cell development GO:0014032 62 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
sensory perception of smell GO:0007608 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
response to glucose GO:0009749 3 0.012
cellular amine metabolic process GO:0044106 2 0.011
cell junction maintenance GO:0034331 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
cellular protein localization GO:0034613 20 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
response to alkaloid GO:0043279 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
spermatid differentiation GO:0048515 2 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of response to stress GO:0080134 36 0.011
response to light stimulus GO:0009416 46 0.011
defense response GO:0006952 47 0.011
blood vessel development GO:0001568 246 0.011
positive regulation of multi organism process GO:0043902 3 0.011
membrane invagination GO:0010324 1 0.011
establishment of endothelial barrier GO:0061028 3 0.011
determination of bilateral symmetry GO:0009855 204 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
embryonic pattern specification GO:0009880 44 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
regulation of blood coagulation GO:0030193 1 0.011
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.011
cell part morphogenesis GO:0032990 246 0.011
response to carbohydrate GO:0009743 3 0.011
b cell activation GO:0042113 2 0.011
regulation of axon extension GO:0030516 24 0.010
membrane fusion GO:0061025 2 0.010
regulation of developmental process GO:0050793 247 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
negative regulation of protein transport GO:0051224 3 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
apical junction assembly GO:0043297 1 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
melanocyte migration GO:0097324 4 0.010
small molecule metabolic process GO:0044281 77 0.010
organic substance biosynthetic process GO:1901576 289 0.010
death GO:0016265 121 0.010
epidermis morphogenesis GO:0048730 4 0.010
cellular response to methanol GO:0071405 4 0.010
multi organism process GO:0051704 134 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
single organism cellular localization GO:1902580 46 0.010

sc:d0144 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
disease of anatomical entity DOID:7 0 0.016
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
cardiovascular system disease DOID:1287 0 0.013
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012