Danio rerio

0 known processes

dtnbp1a

dystrobrevin binding protein 1a

(Aliases: MGC56462,zgc:56462,dtnbp1)

dtnbp1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transport GO:0051169 4 0.171
gtp metabolic process GO:0046039 4 0.160
regulation of establishment of protein localization GO:0070201 4 0.120
regulation of cell communication GO:0010646 232 0.110
Mouse
pigmentation GO:0043473 85 0.105
aging GO:0007568 2 0.101
maintenance of location GO:0051235 4 0.090
guanosine containing compound metabolic process GO:1901068 4 0.089
establishment of protein localization to organelle GO:0072594 4 0.081
immune system process GO:0002376 241 0.076
response to external stimulus GO:0009605 264 0.070
nucleocytoplasmic transport GO:0006913 4 0.068
regulation of protein transport GO:0051223 3 0.061
guanosine containing compound catabolic process GO:1901069 2 0.058
organelle organization GO:0006996 227 0.057
Mouse
protein import into nucleus GO:0006606 3 0.056
larval development GO:0002164 2 0.054
phagocytosis GO:0006909 3 0.053
locomotion GO:0040011 313 0.052
leukocyte proliferation GO:0070661 1 0.050
single organism metabolic process GO:0044710 217 0.049
cellular component assembly GO:0022607 170 0.048
regulation of multicellular organismal development GO:2000026 223 0.047
cellular amine metabolic process GO:0044106 2 0.047
gtp catabolic process GO:0006184 2 0.046
autophagy GO:0006914 4 0.044
small molecule metabolic process GO:0044281 77 0.044
catechol containing compound biosynthetic process GO:0009713 2 0.044
stem cell division GO:0017145 1 0.043
regulation of reactive oxygen species metabolic process GO:2000377 2 0.042
regulation of cytoplasmic transport GO:1903649 4 0.042
protein targeting to nucleus GO:0044744 3 0.041
regulation of signaling GO:0023051 235 0.040
Mouse
erk1 and erk2 cascade GO:0070371 4 0.040
generation of neurons GO:0048699 385 0.040
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.040
mononuclear cell proliferation GO:0032943 1 0.039
protein localization to plasma membrane GO:0072659 1 0.039
positive regulation of transport GO:0051050 2 0.039
Mouse
protein localization to nucleus GO:0034504 3 0.038
regulation of nucleoside metabolic process GO:0009118 2 0.038
regulation of cytokine production GO:0001817 3 0.037
positive regulation of cellular process GO:0048522 201 0.037
Mouse
protein import GO:0017038 3 0.037
cellular amino acid metabolic process GO:0006520 7 0.036
single organism transport GO:0044765 206 0.035
Mouse
amine metabolic process GO:0009308 2 0.035
cytokinesis GO:0000910 3 0.035
membrane fusion GO:0061025 2 0.034
cell projection morphogenesis GO:0048858 244 0.033
Mouse
nuclear import GO:0051170 3 0.033
regulation of cell activation GO:0050865 1 0.033
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
single organism nuclear import GO:1902593 3 0.032
cellular ketone metabolic process GO:0042180 11 0.032
cell migration GO:0016477 237 0.032
secondary metabolic process GO:0019748 3 0.032
signal transduction GO:0007165 455 0.031
lymphocyte proliferation GO:0046651 1 0.031
central nervous system development GO:0007417 387 0.031
regulation of signal transduction GO:0009966 225 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
negative regulation of protein kinase activity GO:0006469 4 0.030
positive regulation of cell activation GO:0050867 1 0.030
cellular response to starvation GO:0009267 1 0.030
brain development GO:0007420 293 0.030
single organism cellular localization GO:1902580 46 0.029
neuroblast proliferation GO:0007405 2 0.029
organic acid metabolic process GO:0006082 31 0.029
chemotaxis GO:0006935 104 0.029
digestive system development GO:0055123 289 0.029
regulation of response to stimulus GO:0048583 269 0.029
single organism membrane fusion GO:0044801 2 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.028
response to nutrient GO:0007584 3 0.028
positive regulation of secretion by cell GO:1903532 1 0.028
Mouse
macromolecule localization GO:0033036 54 0.028
membrane invagination GO:0010324 1 0.028
oxoacid metabolic process GO:0043436 31 0.028
stem cell proliferation GO:0072089 4 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
catechol containing compound metabolic process GO:0009712 2 0.027
positive regulation of catabolic process GO:0009896 4 0.027
multi organism process GO:0051704 134 0.027
establishment of localization GO:0051234 244 0.027
Mouse
cellular response to nutrient levels GO:0031669 2 0.027
response to uv GO:0009411 3 0.027
regulation of programmed cell death GO:0043067 101 0.027
regulation of nucleotide catabolic process GO:0030811 2 0.027
cell cell signaling GO:0007267 52 0.027
Mouse
synaptic transmission cholinergic GO:0007271 4 0.026
regulation of biological quality GO:0065008 263 0.026
Mouse
regulation of cell development GO:0060284 100 0.026
determination of left right symmetry GO:0007368 179 0.026
regulation of binding GO:0051098 3 0.026
cytoskeleton organization GO:0007010 96 0.026
Mouse
lipid storage GO:0019915 1 0.025
single organism organelle organization GO:1902589 199 0.025
Mouse
positive regulation of biological process GO:0048518 253 0.025
Mouse
exocytosis GO:0006887 1 0.025
specification of symmetry GO:0009799 204 0.025
negative regulation of kinase activity GO:0033673 4 0.025
organelle fusion GO:0048284 3 0.024
rna localization GO:0006403 4 0.024
striated muscle tissue development GO:0014706 110 0.024
regulation of gtpase activity GO:0043087 2 0.024
adherens junction organization GO:0034332 4 0.024
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
positive regulation of nucleotide catabolic process GO:0030813 1 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
determination of bilateral symmetry GO:0009855 204 0.023
response to transition metal nanoparticle GO:1990267 28 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.022
meiotic cell cycle process GO:1903046 3 0.022
regulation of cell differentiation GO:0045595 142 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
regulation of synapse organization GO:0050807 3 0.022
regulation of autophagy GO:0010506 3 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
heterocycle metabolic process GO:0046483 290 0.022
cellular response to extracellular stimulus GO:0031668 2 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
organelle assembly GO:0070925 110 0.021
response to external biotic stimulus GO:0043207 97 0.021
programmed cell death GO:0012501 119 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
neuron differentiation GO:0030182 353 0.021
Human Mouse
multicellular organismal signaling GO:0035637 22 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
regulation of synaptic plasticity GO:0048167 1 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
pigment granule organization GO:0048753 4 0.020
response to carbohydrate GO:0009743 3 0.020
immune system development GO:0002520 191 0.020
response to organic substance GO:0010033 153 0.020
blood circulation GO:0008015 87 0.020
defense response GO:0006952 47 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
regulation of multicellular organism growth GO:0040014 4 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
response to glucocorticoid GO:0051384 1 0.019
intracellular signal transduction GO:0035556 85 0.019
protein secretion GO:0009306 1 0.019
regulation of wound healing GO:0061041 2 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.019
response to hexose GO:0009746 3 0.019
positive regulation of cell cycle GO:0045787 3 0.019
small molecule catabolic process GO:0044282 3 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
female sex differentiation GO:0046660 4 0.019
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
dopamine biosynthetic process GO:0042416 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
endosomal transport GO:0016197 2 0.018
regulation of neuronal synaptic plasticity GO:0048168 1 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
catecholamine metabolic process GO:0006584 2 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
nuclear export GO:0051168 1 0.018
regulation of protein localization to plasma membrane GO:1903076 1 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of oocyte development GO:0060281 3 0.018
muscle cell development GO:0055001 115 0.017
synaptic vesicle transport GO:0048489 1 0.017
Mouse
cellular biosynthetic process GO:0044249 286 0.017
cellular protein catabolic process GO:0044257 4 0.017
axon development GO:0061564 166 0.017
alcohol biosynthetic process GO:0046165 2 0.017
muscle cell differentiation GO:0042692 139 0.017
cellular modified amino acid metabolic process GO:0006575 3 0.017
response to biotic stimulus GO:0009607 97 0.017
retinoic acid receptor signaling pathway GO:0048384 16 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
neuron development GO:0048666 262 0.017
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.017
renal system development GO:0072001 94 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.016
cell aging GO:0007569 2 0.016
digestive tract development GO:0048565 265 0.016
hemopoiesis GO:0030097 183 0.016
cell projection organization GO:0030030 284 0.016
Human Mouse
regulation of organelle assembly GO:1902115 4 0.016
response to monosaccharide GO:0034284 3 0.016
adherens junction maintenance GO:0034334 2 0.016
catabolic process GO:0009056 32 0.016
cell morphogenesis GO:0000902 289 0.016
Mouse
cell death GO:0008219 121 0.016
cell part morphogenesis GO:0032990 246 0.016
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
cortical cytoskeleton organization GO:0030865 1 0.016
smooth muscle contraction GO:0006939 2 0.016
developmental pigmentation GO:0048066 48 0.015
transport GO:0006810 220 0.015
Mouse
establishment of localization in cell GO:0051649 77 0.015
Mouse
regulation of apoptotic process GO:0042981 98 0.015
rna transport GO:0050658 2 0.015
b cell activation GO:0042113 2 0.015
positive regulation of secretion GO:0051047 1 0.015
Mouse
epithelial tube morphogenesis GO:0060562 148 0.015
vesicle organization GO:0016050 6 0.015
Mouse
nucleic acid transport GO:0050657 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
regulation of intracellular ph GO:0051453 1 0.015
activation of mapk activity GO:0000187 3 0.015
regulation of synapse assembly GO:0051963 3 0.015
response to stress GO:0006950 263 0.015
Mouse
synaptic transmission GO:0007268 35 0.015
Mouse
cell cell recognition GO:0009988 1 0.015
regulation of nervous system development GO:0051960 90 0.015
intracellular transport GO:0046907 32 0.015
Mouse
cell motility GO:0048870 244 0.015
phagocytosis engulfment GO:0006911 1 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
neuron projection morphogenesis GO:0048812 161 0.015
Mouse
carboxylic acid catabolic process GO:0046395 3 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
response to vitamin GO:0033273 3 0.014
cytoplasmic transport GO:0016482 11 0.014
response to other organism GO:0051707 97 0.014
positive regulation of developmental process GO:0051094 50 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
blood vessel morphogenesis GO:0048514 216 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
melanosome organization GO:0032438 4 0.014
cellular amide metabolic process GO:0043603 4 0.014
response to drug GO:0042493 3 0.014
liver development GO:0001889 96 0.014
localization of cell GO:0051674 244 0.014
protein acetylation GO:0006473 2 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
posterior lateral line system development GO:0048915 46 0.014
superoxide metabolic process GO:0006801 2 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
regulation of inflammatory response GO:0050727 2 0.014
dopamine metabolic process GO:0042417 2 0.014
multicellular organism growth GO:0035264 4 0.013
mesoderm development GO:0007498 88 0.013
cortical actin cytoskeleton organization GO:0030866 1 0.013
lateral inhibition GO:0046331 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of developmental process GO:0050793 247 0.013
tube morphogenesis GO:0035239 349 0.013
muscle structure development GO:0061061 196 0.013
vasculature development GO:0001944 278 0.013
negative regulation of biological process GO:0048519 304 0.013
cell substrate adhesion GO:0031589 4 0.013
response to inorganic substance GO:0010035 38 0.013
response to corticosteroid GO:0031960 1 0.013
endosome to lysosome transport GO:0008333 1 0.013
regulation of blood pressure GO:0008217 1 0.013
organic substance biosynthetic process GO:1901576 289 0.013
response to glucose GO:0009749 3 0.013
positive regulation of striated muscle cell differentiation GO:0051155 1 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
cellular component movement GO:0006928 335 0.013
Mouse
regulation of neurogenesis GO:0050767 87 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
protein localization to vacuole GO:0072665 1 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
cellular response to external stimulus GO:0071496 2 0.013
retina development in camera type eye GO:0060041 146 0.013
monoamine transport GO:0015844 1 0.013
Mouse
positive regulation of leukocyte differentiation GO:1902107 1 0.013
phosphorus metabolic process GO:0006793 109 0.013
catecholamine biosynthetic process GO:0042423 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
establishment of rna localization GO:0051236 3 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
antimicrobial humoral response GO:0019730 2 0.012
lipid digestion GO:0044241 3 0.012
regulation of blood coagulation GO:0030193 1 0.012
head development GO:0060322 303 0.012
golgi vesicle transport GO:0048193 3 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
peptide metabolic process GO:0006518 1 0.012
heart contraction GO:0060047 71 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
meiotic nuclear division GO:0007126 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
b cell mediated immunity GO:0019724 3 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
lipid catabolic process GO:0016042 4 0.012
negative regulation of cellular process GO:0048523 283 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
angiogenesis GO:0001525 158 0.012
vacuolar transport GO:0007034 2 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of catalytic activity GO:0050790 55 0.012
notochord development GO:0030903 54 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
hepaticobiliary system development GO:0061008 98 0.012
sequestering of calcium ion GO:0051208 3 0.012
response to hypoxia GO:0001666 25 0.012
pigment cell differentiation GO:0050931 38 0.011
regulation of protein catabolic process GO:0042176 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell junction maintenance GO:0034331 2 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
eye development GO:0001654 277 0.011
positive regulation of cell division GO:0051781 2 0.011
astrocyte differentiation GO:0048708 1 0.011
cilium organization GO:0044782 71 0.011
single organism intracellular transport GO:1902582 25 0.011
Mouse
regulation of localization GO:0032879 104 0.011
Mouse
wound healing GO:0042060 90 0.011
Mouse
embryonic organ development GO:0048568 381 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
response to ketone GO:1901654 1 0.011
digestive tract mesoderm development GO:0007502 1 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
notch signaling pathway GO:0007219 35 0.011
camera type eye development GO:0043010 222 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
death GO:0016265 121 0.010
heart morphogenesis GO:0003007 156 0.010
regulation of metal ion transport GO:0010959 4 0.010
cellular component morphogenesis GO:0032989 336 0.010
Mouse
immunoglobulin mediated immune response GO:0016064 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
glucose homeostasis GO:0042593 1 0.010
muscle tissue development GO:0060537 110 0.010
actin cytoskeleton organization GO:0030036 63 0.010
Mouse
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
germ line stem cell division GO:0042078 1 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
protein modification by small protein removal GO:0070646 1 0.010
tissue migration GO:0090130 37 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
Mouse
regulation of nucleotide metabolic process GO:0006140 17 0.010
cell projection assembly GO:0030031 64 0.010
centrosome cycle GO:0007098 1 0.010
lateral line system development GO:0048925 76 0.010
nucleobase containing compound transport GO:0015931 2 0.010
regulation of gene expression GO:0010468 265 0.010
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
muscle fiber development GO:0048747 52 0.010

dtnbp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.021
immune system disease DOID:2914 0 0.019
hematopoietic system disease DOID:74 0 0.019
retinal disease DOID:5679 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
disease of metabolism DOID:0014667 0 0.011