Danio rerio

0 known processes

tspan12

tetraspanin 12

(Aliases: zgc:63880,MGC63880,tm4sf12)

tspan12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.068
aging GO:0007568 2 0.048
maintenance of location GO:0051235 4 0.041
multicellular organism growth GO:0035264 4 0.039
positive regulation of transport GO:0051050 2 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
amine metabolic process GO:0009308 2 0.034
regulation of establishment of protein localization GO:0070201 4 0.033
cellular protein catabolic process GO:0044257 4 0.033
cellular amine metabolic process GO:0044106 2 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
modification dependent protein catabolic process GO:0019941 3 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
lipid storage GO:0019915 1 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
phagocytosis GO:0006909 3 0.029
response to drug GO:0042493 3 0.028
positive regulation of catabolic process GO:0009896 4 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of protein transport GO:0051223 3 0.027
golgi vesicle transport GO:0048193 3 0.027
signal transduction GO:0007165 455 0.027
nitrogen compound metabolic process GO:0006807 319 0.026
mitochondrion organization GO:0007005 4 0.026
response to topologically incorrect protein GO:0035966 2 0.026
gtp metabolic process GO:0046039 4 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
cellular component movement GO:0006928 335 0.025
sensory organ development GO:0007423 393 0.025
meiotic nuclear division GO:0007126 4 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
nuclear transport GO:0051169 4 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
regulation of binding GO:0051098 3 0.024
positive regulation of cell cycle GO:0045787 3 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
regulation of mrna processing GO:0050684 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
gtp catabolic process GO:0006184 2 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
adult behavior GO:0030534 2 0.022
regulation of protein complex assembly GO:0043254 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
protein localization to nucleus GO:0034504 3 0.022
protein import GO:0017038 3 0.022
meiotic cell cycle process GO:1903046 3 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
cytokinesis GO:0000910 3 0.022
regulation of biological quality GO:0065008 263 0.022
transport GO:0006810 220 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
establishment of localization GO:0051234 244 0.021
protein localization to plasma membrane GO:0072659 1 0.021
eye development GO:0001654 277 0.021
organelle fusion GO:0048284 3 0.021
single organism localization GO:1902578 225 0.021
endosomal transport GO:0016197 2 0.021
heterocycle metabolic process GO:0046483 290 0.021
stem cell proliferation GO:0072089 4 0.021
regulation of metabolic process GO:0019222 359 0.021
cellular ketone metabolic process GO:0042180 11 0.021
cell morphogenesis GO:0000902 289 0.021
regulation of cytokine production GO:0001817 3 0.021
response to stress GO:0006950 263 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
cellular component disassembly GO:0022411 1 0.020
response to chemical GO:0042221 320 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
neuron differentiation GO:0030182 353 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
regulation of cell shape GO:0008360 1 0.020
rna metabolic process GO:0016070 219 0.020
biosynthetic process GO:0009058 294 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
regulation of cytoplasmic transport GO:1903649 4 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of mrna splicing via spliceosome GO:0048024 3 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
regulation of synapse organization GO:0050807 3 0.019
membrane fusion GO:0061025 2 0.019
gene expression GO:0010467 252 0.019
nuclear import GO:0051170 3 0.019
protein secretion GO:0009306 1 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
neuron development GO:0048666 262 0.019
regulation of circadian rhythm GO:0042752 4 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of cell activation GO:0050865 1 0.019
regionalization GO:0003002 274 0.019
cellular biosynthetic process GO:0044249 286 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.019
single organism transport GO:0044765 206 0.019
tube morphogenesis GO:0035239 349 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
organic substance biosynthetic process GO:1901576 289 0.019
small molecule metabolic process GO:0044281 77 0.018
cellular respiration GO:0045333 3 0.018
cellular amide metabolic process GO:0043603 4 0.018
central nervous system development GO:0007417 387 0.018
single organism metabolic process GO:0044710 217 0.018
cell projection morphogenesis GO:0048858 244 0.018
autophagy GO:0006914 4 0.018
locomotion GO:0040011 313 0.018
cell migration GO:0016477 237 0.018
cognition GO:0050890 1 0.018
tissue remodeling GO:0048771 4 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of cell communication GO:0010646 232 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
organic acid metabolic process GO:0006082 31 0.018
single organism membrane fusion GO:0044801 2 0.018
protein acetylation GO:0006473 2 0.018
single organism nuclear import GO:1902593 3 0.018
generation of neurons GO:0048699 385 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
negative regulation of biological process GO:0048519 304 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
cellular response to starvation GO:0009267 1 0.018
nucleic acid metabolic process GO:0090304 244 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
embryonic organ development GO:0048568 381 0.017
localization of cell GO:0051674 244 0.017
neuroblast proliferation GO:0007405 2 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of primary metabolic process GO:0080090 311 0.017
negative regulation of kinase activity GO:0033673 4 0.017
positive regulation of secretion GO:0051047 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
cell motility GO:0048870 244 0.017
system process GO:0003008 185 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
regulation of signaling GO:0023051 235 0.017
germ line stem cell maintenance GO:0030718 2 0.017
regulation of response to stimulus GO:0048583 269 0.017
glucose homeostasis GO:0042593 1 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
camera type eye development GO:0043010 222 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
phagocytosis engulfment GO:0006911 1 0.017
protein import into nucleus GO:0006606 3 0.017
regulation of protein targeting GO:1903533 2 0.017
cell part morphogenesis GO:0032990 246 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
protein complex disassembly GO:0043241 1 0.016
digestive system development GO:0055123 289 0.016
nucleic acid templated transcription GO:0097659 181 0.016
regulation of synapse assembly GO:0051963 3 0.016
regulation of metal ion transport GO:0010959 4 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
exocytosis GO:0006887 1 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
transcription dna templated GO:0006351 181 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
protein polymerization GO:0051258 4 0.016
macromolecular complex disassembly GO:0032984 1 0.016
atp catabolic process GO:0006200 4 0.016
cell projection organization GO:0030030 284 0.016
organelle organization GO:0006996 227 0.016
membrane invagination GO:0010324 1 0.016
response to uv GO:0009411 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
digestive tract morphogenesis GO:0048546 231 0.016
single organism organelle organization GO:1902589 199 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cell substrate adhesion GO:0031589 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.015
peptide transport GO:0015833 1 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
chemosensory behavior GO:0007635 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
response to external stimulus GO:0009605 264 0.015
compound eye development GO:0048749 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
negative regulation of catabolic process GO:0009895 3 0.015
rna biosynthetic process GO:0032774 181 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
protein acylation GO:0043543 3 0.015
synaptic vesicle localization GO:0097479 1 0.015
sensory organ morphogenesis GO:0090596 200 0.015
response to monosaccharide GO:0034284 3 0.015
response to carbohydrate GO:0009743 3 0.015
regulation of inflammatory response GO:0050727 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
heart development GO:0007507 313 0.015
positive regulation of biological process GO:0048518 253 0.015
spermatid development GO:0007286 2 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
protein metabolic process GO:0019538 183 0.015
brain development GO:0007420 293 0.015
regulation of gene expression GO:0010468 265 0.015
synaptic vesicle transport GO:0048489 1 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
vasculature development GO:0001944 278 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
gastrulation GO:0007369 208 0.015
cellular response to nutrient levels GO:0031669 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
stem cell division GO:0017145 1 0.015
cellular component biogenesis GO:0044085 178 0.015
muscle structure development GO:0061061 196 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.014
regulation of developmental process GO:0050793 247 0.014
peptidyl serine modification GO:0018209 2 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
positive regulation of cytokine production GO:0001819 2 0.014
cellular response to radiation GO:0071478 4 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
regulation of jak stat cascade GO:0046425 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
sequestering of metal ion GO:0051238 3 0.014
microtubule organizing center organization GO:0031023 1 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
hormone transport GO:0009914 2 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
protein dephosphorylation GO:0006470 3 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
cellular response to topologically incorrect protein GO:0035967 2 0.014
determination of bilateral symmetry GO:0009855 204 0.014
vacuolar transport GO:0007034 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
hemopoiesis GO:0030097 183 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
positive regulation of translation GO:0045727 1 0.014
spermatid differentiation GO:0048515 2 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
protein polyubiquitination GO:0000209 4 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
chordate embryonic development GO:0043009 271 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
positive regulation of cell activation GO:0050867 1 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
immune system development GO:0002520 191 0.013
somatic muscle development GO:0007525 4 0.013
growth GO:0040007 174 0.013
response to hexose GO:0009746 3 0.013
head development GO:0060322 303 0.013
regulation of protein polymerization GO:0032271 2 0.013
digestive tract development GO:0048565 265 0.013
actin filament polymerization GO:0030041 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
response to glucose GO:0009749 3 0.013
blood vessel development GO:0001568 246 0.013
regulation of blood pressure GO:0008217 1 0.013
regulation of rna metabolic process GO:0051252 224 0.013
homeostatic process GO:0042592 142 0.013
spindle assembly GO:0051225 2 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
b cell activation GO:0042113 2 0.013
protein homooligomerization GO:0051260 3 0.013
centrosome organization GO:0051297 1 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
mitotic cytokinesis GO:0000281 3 0.013
regulation of cell projection assembly GO:0060491 4 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
positive regulation of cellular process GO:0048522 201 0.013
cell matrix adhesion GO:0007160 4 0.012
secondary metabolic process GO:0019748 3 0.012
cellular component assembly GO:0022607 170 0.012
regulation of transcription dna templated GO:0006355 213 0.012
nuclear export GO:0051168 1 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
immune system process GO:0002376 241 0.012
rna localization GO:0006403 4 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
mitochondrial transport GO:0006839 2 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
cilium morphogenesis GO:0060271 85 0.012
axon development GO:0061564 166 0.012
carbohydrate homeostasis GO:0033500 1 0.012
antimicrobial humoral response GO:0019730 2 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
developmental growth GO:0048589 166 0.012
single fertilization GO:0007338 3 0.012
axonogenesis GO:0007409 152 0.012
regulation of dna replication GO:0006275 3 0.012
cellular response to light stimulus GO:0071482 4 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
response to organic substance GO:0010033 153 0.012
neurotransmitter transport GO:0006836 2 0.012
specification of symmetry GO:0009799 204 0.012
positive regulation of immune effector process GO:0002699 3 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
sequestering of calcium ion GO:0051208 3 0.012
organism emergence from protective structure GO:0071684 4 0.012
glial cell migration GO:0008347 3 0.012
negative regulation of defense response GO:0031348 2 0.012
leukocyte proliferation GO:0070661 1 0.011
neuron projection development GO:0031175 180 0.011
response to hydrogen peroxide GO:0042542 3 0.011
neurotransmitter secretion GO:0007269 2 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
cytokinetic process GO:0032506 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
somatic stem cell maintenance GO:0035019 1 0.011
lateral inhibition GO:0046331 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of muscle contraction GO:0006937 3 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
fertilization GO:0009566 3 0.011
regulation of exocytosis GO:0017157 1 0.011
entrainment of circadian clock GO:0009649 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
protein stabilization GO:0050821 2 0.011
response to alkaloid GO:0043279 2 0.011
transmembrane transport GO:0055085 120 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of localization GO:0032879 104 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
wnt signaling pathway GO:0016055 80 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
response to unfolded protein GO:0006986 2 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
developmental programmed cell death GO:0010623 4 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
double strand break repair GO:0006302 3 0.011
angiogenesis GO:0001525 158 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
cellular localization GO:0051641 97 0.011
alcohol biosynthetic process GO:0046165 2 0.011
adherens junction organization GO:0034332 4 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
blood vessel morphogenesis GO:0048514 216 0.011
eye morphogenesis GO:0048592 144 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
post embryonic organ development GO:0048569 4 0.011
negative regulation of secretion GO:0051048 2 0.011
multi organism cellular process GO:0044764 2 0.011
hormone biosynthetic process GO:0042446 3 0.011
female gonad development GO:0008585 4 0.011
hormone secretion GO:0046879 2 0.011
response to nutrient GO:0007584 3 0.011
epithelial cell differentiation GO:0030855 116 0.010
negative regulation of protein transport GO:0051224 3 0.010
macromolecule modification GO:0043412 111 0.010
primary neural tube formation GO:0014020 1 0.010
apoptotic process GO:0006915 116 0.010
female sex differentiation GO:0046660 4 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
regulation of growth rate GO:0040009 1 0.010
response to wounding GO:0009611 116 0.010
lamellipodium assembly GO:0030032 1 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
appendage development GO:0048736 80 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cell death GO:0008219 121 0.010
regulation of hormone secretion GO:0046883 2 0.010
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
death GO:0016265 121 0.010
nucleobase containing compound transport GO:0015931 2 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
nucleic acid transport GO:0050657 2 0.010
small molecule catabolic process GO:0044282 3 0.010
er nucleus signaling pathway GO:0006984 2 0.010
anterior posterior pattern specification GO:0009952 152 0.010
regulation of ras gtpase activity GO:0032318 2 0.010
regulation of transporter activity GO:0032409 2 0.010

tspan12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
nervous system disease DOID:863 0 0.020
Human
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.013
eye disease DOID:5614 0 0.011
Human
eye and adnexa disease DOID:1492 0 0.011
Human
sensory system disease DOID:0050155 0 0.011
Human