Danio rerio

0 known processes

npsnl

nephrosin-like

npsnl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.079
i kappab kinase nf kappab signaling GO:0007249 4 0.056
hematopoietic or lymphoid organ development GO:0048534 191 0.049
nucleic acid metabolic process GO:0090304 244 0.048
positive regulation of transport GO:0051050 2 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.038
single organism localization GO:1902578 225 0.038
cellular response to lipopolysaccharide GO:0071222 3 0.037
organic substance biosynthetic process GO:1901576 289 0.036
transport GO:0006810 220 0.036
nitrogen compound metabolic process GO:0006807 319 0.035
regulation of metabolic process GO:0019222 359 0.035
organic cyclic compound metabolic process GO:1901360 301 0.035
establishment of localization GO:0051234 244 0.035
regulation of cytokine production GO:0001817 3 0.035
establishment of protein localization to organelle GO:0072594 4 0.034
rna biosynthetic process GO:0032774 181 0.034
response to chemical GO:0042221 320 0.034
cellular response to biotic stimulus GO:0071216 3 0.033
gene expression GO:0010467 252 0.033
nuclear transport GO:0051169 4 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
aging GO:0007568 2 0.031
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.031
regulation of biosynthetic process GO:0009889 250 0.031
protein localization to nucleus GO:0034504 3 0.031
regulation of nucleic acid templated transcription GO:1903506 213 0.030
response to stress GO:0006950 263 0.029
cellular amine metabolic process GO:0044106 2 0.029
toll like receptor signaling pathway GO:0002224 4 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
hemopoiesis GO:0030097 183 0.029
multicellular organism growth GO:0035264 4 0.029
cellular response to molecule of bacterial origin GO:0071219 3 0.029
immune system process GO:0002376 241 0.028
cellular biosynthetic process GO:0044249 286 0.028
cellular response to external stimulus GO:0071496 2 0.028
regulation of signal transduction GO:0009966 225 0.028
rna metabolic process GO:0016070 219 0.028
single organism transport GO:0044765 206 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.027
embryonic organ development GO:0048568 381 0.027
signal transduction GO:0007165 455 0.027
nucleic acid templated transcription GO:0097659 181 0.027
response to external stimulus GO:0009605 264 0.026
protein targeting to nucleus GO:0044744 3 0.026
regulation of protein targeting GO:1903533 2 0.026
heterocycle metabolic process GO:0046483 290 0.026
regulation of response to stimulus GO:0048583 269 0.026
aromatic compound biosynthetic process GO:0019438 217 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
regulation of rna biosynthetic process GO:2001141 213 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
positive regulation of immune effector process GO:0002699 3 0.025
biosynthetic process GO:0009058 294 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
regulation of cell activation GO:0050865 1 0.024
positive regulation of biological process GO:0048518 253 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
phagocytosis GO:0006909 3 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
eye development GO:0001654 277 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
cellular macromolecule metabolic process GO:0044260 391 0.023
regulation of protein complex assembly GO:0043254 3 0.023
regulation of rna metabolic process GO:0051252 224 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
regulation of transcription dna templated GO:0006355 213 0.023
tube morphogenesis GO:0035239 349 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.022
response to external biotic stimulus GO:0043207 97 0.022
transcription dna templated GO:0006351 181 0.022
regulation of primary metabolic process GO:0080090 311 0.022
protein import into nucleus GO:0006606 3 0.022
response to other organism GO:0051707 97 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of protein transport GO:0051223 3 0.022
response to alkaloid GO:0043279 2 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
regulation of synaptic plasticity GO:0048167 1 0.021
protein metabolic process GO:0019538 183 0.021
maintenance of location GO:0051235 4 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
amine metabolic process GO:0009308 2 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.020
single organism nuclear import GO:1902593 3 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
regulation of signaling GO:0023051 235 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
regulation of blood pressure GO:0008217 1 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
erythrocyte homeostasis GO:0034101 55 0.019
camera type eye development GO:0043010 222 0.019
regulation of mrna processing GO:0050684 3 0.019
sleep GO:0030431 1 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
sensory organ development GO:0007423 393 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
b cell activation GO:0042113 2 0.018
positive regulation of cytokine production GO:0001819 2 0.018
nuclear import GO:0051170 3 0.018
protein import GO:0017038 3 0.018
cellular ketone metabolic process GO:0042180 11 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
protein heterooligomerization GO:0051291 1 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
cognition GO:0050890 1 0.018
tetrapyrrole metabolic process GO:0033013 10 0.018
heme metabolic process GO:0042168 9 0.018
cytokinesis GO:0000910 3 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
regulation of protein catabolic process GO:0042176 1 0.018
system process GO:0003008 185 0.017
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.017
regulation of biological quality GO:0065008 263 0.017
response to organic substance GO:0010033 153 0.017
rna localization GO:0006403 4 0.017
regulation of gene expression GO:0010468 265 0.017
ion transport GO:0006811 114 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
ion transmembrane transport GO:0034220 91 0.017
transmembrane transport GO:0055085 120 0.017
regulation of cell communication GO:0010646 232 0.017
autophagy GO:0006914 4 0.017
organelle organization GO:0006996 227 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
cellular component biogenesis GO:0044085 178 0.017
negative regulation of mapk cascade GO:0043409 4 0.017
stem cell proliferation GO:0072089 4 0.017
cellular protein catabolic process GO:0044257 4 0.017
porphyrin containing compound metabolic process GO:0006778 10 0.017
antimicrobial humoral response GO:0019730 2 0.017
homeostatic process GO:0042592 142 0.017
cellular response to extracellular stimulus GO:0031668 2 0.016
cellular component disassembly GO:0022411 1 0.016
protein secretion GO:0009306 1 0.016
iron ion homeostasis GO:0055072 4 0.016
positive regulation of catabolic process GO:0009896 4 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
regulation of circadian rhythm GO:0042752 4 0.016
mitochondrion organization GO:0007005 4 0.016
rhombomere 5 development GO:0021571 4 0.016
positive regulation of cell killing GO:0031343 2 0.016
peptide transport GO:0015833 1 0.016
porphyrin containing compound biosynthetic process GO:0006779 8 0.016
positive regulation of cell activation GO:0050867 1 0.016
wnt signaling pathway GO:0016055 80 0.016
protein acetylation GO:0006473 2 0.016
gtp catabolic process GO:0006184 2 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
cell killing GO:0001906 2 0.015
small molecule metabolic process GO:0044281 77 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
protein polymerization GO:0051258 4 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
mononuclear cell proliferation GO:0032943 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
regulation of metal ion transport GO:0010959 4 0.015
negative regulation of cellular process GO:0048523 283 0.015
gtp metabolic process GO:0046039 4 0.015
cellular component movement GO:0006928 335 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
lipid storage GO:0019915 1 0.014
protein localization to plasma membrane GO:0072659 1 0.014
synaptic transmission cholinergic GO:0007271 4 0.014
neuron development GO:0048666 262 0.014
cell projection organization GO:0030030 284 0.014
myeloid cell homeostasis GO:0002262 56 0.014
generation of neurons GO:0048699 385 0.014
cell morphogenesis GO:0000902 289 0.014
lymphocyte proliferation GO:0046651 1 0.014
synaptic target recognition GO:0008039 1 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
immune system development GO:0002520 191 0.014
cell substrate adhesion GO:0031589 4 0.014
cell matrix adhesion GO:0007160 4 0.014
regulation of inflammatory response GO:0050727 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
macromolecular complex disassembly GO:0032984 1 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
compound eye development GO:0048749 2 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
neuron differentiation GO:0030182 353 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
programmed cell death GO:0012501 119 0.013
negative regulation of metabolic process GO:0009892 86 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
response to biotic stimulus GO:0009607 97 0.013
inorganic anion transport GO:0015698 25 0.013
oxoacid metabolic process GO:0043436 31 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
monovalent inorganic cation transport GO:0015672 42 0.013
myeloid cell differentiation GO:0030099 86 0.013
determination of bilateral symmetry GO:0009855 204 0.013
cellular amide metabolic process GO:0043603 4 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
cellular response to starvation GO:0009267 1 0.013
protein dephosphorylation GO:0006470 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
cellular localization GO:0051641 97 0.013
retina development in camera type eye GO:0060041 146 0.012
cellular response to nutrient levels GO:0031669 2 0.012
locomotor rhythm GO:0045475 3 0.012
determination of left right symmetry GO:0007368 179 0.012
cell part morphogenesis GO:0032990 246 0.012
amino acid transport GO:0006865 2 0.012
cation transport GO:0006812 81 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
leukocyte proliferation GO:0070661 1 0.012
protein complex localization GO:0031503 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
muscle structure development GO:0061061 196 0.012
response to drug GO:0042493 3 0.012
regulation of dendrite development GO:0050773 3 0.012
protein homooligomerization GO:0051260 3 0.012
neurotransmitter transport GO:0006836 2 0.012
stem cell maintenance GO:0019827 4 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
somatic muscle development GO:0007525 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
defense response to fungus GO:0050832 2 0.011
sodium ion transport GO:0006814 24 0.011
central nervous system development GO:0007417 387 0.011
adult behavior GO:0030534 2 0.011
bone remodeling GO:0046849 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
protein acylation GO:0043543 3 0.011
regulation of developmental process GO:0050793 247 0.011
regulation of binding GO:0051098 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
endosomal transport GO:0016197 2 0.011
response to abiotic stimulus GO:0009628 122 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
nucleic acid transport GO:0050657 2 0.011
multi organism process GO:0051704 134 0.010
apoptotic process GO:0006915 116 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
response to carbohydrate GO:0009743 3 0.010
negative regulation of signal transduction GO:0009968 94 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
regulation of cell killing GO:0031341 2 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
heart looping GO:0001947 94 0.010
growth GO:0040007 174 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
organic acid metabolic process GO:0006082 31 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
single organism membrane fusion GO:0044801 2 0.010
rna transport GO:0050658 2 0.010
positive regulation of secretion GO:0051047 1 0.010
membrane fusion GO:0061025 2 0.010
cilium morphogenesis GO:0060271 85 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
neurological system process GO:0050877 62 0.010
regulation of tube size GO:0035150 2 0.010
response to amphetamine GO:0001975 1 0.010
gas transport GO:0015669 3 0.010

npsnl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of metabolism DOID:0014667 0 0.016
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.012