Danio rerio

0 known processes

mdh1b

malate dehydrogenase 1b, NAD (soluble)

(Aliases: fk59d03,wu:fk59d03,mdhB,mdh1,zgc:56234)

mdh1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.289
aging GO:0007568 2 0.252
nitrogen compound metabolic process GO:0006807 319 0.183
organelle organization GO:0006996 227 0.161
embryo development ending in birth or egg hatching GO:0009792 271 0.159
single organism metabolic process GO:0044710 217 0.153
spermatid development GO:0007286 2 0.143
pyruvate metabolic process GO:0006090 1 0.135
organophosphate biosynthetic process GO:0090407 23 0.134
muscle structure development GO:0061061 196 0.133
organic cyclic compound metabolic process GO:1901360 301 0.118
spermatid differentiation GO:0048515 2 0.113
response to external stimulus GO:0009605 264 0.103
reproduction GO:0000003 40 0.097
muscle cell differentiation GO:0042692 139 0.095
single organism localization GO:1902578 225 0.094
membrane repolarization GO:0086009 2 0.091
regulation of ion transmembrane transporter activity GO:0032412 2 0.091
cellular biosynthetic process GO:0044249 286 0.090
regulation of cell shape GO:0008360 1 0.082
cellular macromolecule metabolic process GO:0044260 391 0.075
cellular component assembly GO:0022607 170 0.073
small molecule metabolic process GO:0044281 77 0.070
establishment of localization GO:0051234 244 0.067
transport GO:0006810 220 0.066
transmembrane transport GO:0055085 120 0.064
regulation of developmental process GO:0050793 247 0.064
regulation of gene expression GO:0010468 265 0.063
ion transport GO:0006811 114 0.059
single organism transport GO:0044765 206 0.059
muscle cell development GO:0055001 115 0.059
regulation of transmembrane transporter activity GO:0022898 2 0.054
response to chemical GO:0042221 320 0.053
neuron neuron synaptic transmission GO:0007270 1 0.052
generation of neurons GO:0048699 385 0.051
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.051
organic substance biosynthetic process GO:1901576 289 0.050
oxoacid metabolic process GO:0043436 31 0.049
heart development GO:0007507 313 0.049
regulation of establishment of protein localization GO:0070201 4 0.048
cellular protein metabolic process GO:0044267 129 0.047
organic anion transport GO:0015711 15 0.043
establishment of localization in cell GO:0051649 77 0.043
striated muscle cell differentiation GO:0051146 129 0.042
organic acid metabolic process GO:0006082 31 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.041
modification dependent protein catabolic process GO:0019941 3 0.041
response to abiotic stimulus GO:0009628 122 0.041
cytoskeleton organization GO:0007010 96 0.040
locomotion GO:0040011 313 0.039
single organism organelle organization GO:1902589 199 0.039
cellular component assembly involved in morphogenesis GO:0010927 107 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
maintenance of location GO:0051235 4 0.038
regulation of transporter activity GO:0032409 2 0.038
cellular respiration GO:0045333 3 0.038
striated muscle cell development GO:0055002 108 0.037
regulation of reproductive process GO:2000241 4 0.037
system process GO:0003008 185 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
positive regulation of transport GO:0051050 2 0.036
blood vessel development GO:0001568 246 0.035
negative regulation of kinase activity GO:0033673 4 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
gene expression GO:0010467 252 0.033
leukocyte proliferation GO:0070661 1 0.033
regulation of biological quality GO:0065008 263 0.033
negative regulation of sequestering of calcium ion GO:0051283 4 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
synaptic transmission cholinergic GO:0007271 4 0.031
multicellular organismal macromolecule metabolic process GO:0044259 2 0.031
nuclear import GO:0051170 3 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
negative regulation of biological process GO:0048519 304 0.031
phototransduction GO:0007602 2 0.030
adherens junction organization GO:0034332 4 0.030
ribonucleotide biosynthetic process GO:0009260 20 0.030
cellular component biogenesis GO:0044085 178 0.030
regulation of transmembrane transport GO:0034762 18 0.030
multi organism process GO:0051704 134 0.030
nuclear transport GO:0051169 4 0.030
regulation of cell death GO:0010941 103 0.030
cellular component morphogenesis GO:0032989 336 0.029
negative regulation of gene expression GO:0010629 65 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
determination of left right symmetry GO:0007368 179 0.029
somitogenesis GO:0001756 87 0.029
positive regulation of cell death GO:0010942 29 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
negative regulation of cellular process GO:0048523 283 0.028
regulation of intracellular protein transport GO:0033157 3 0.028
sequestering of metal ion GO:0051238 3 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
dicarboxylic acid metabolic process GO:0043648 1 0.027
negative regulation of protein kinase activity GO:0006469 4 0.027
actomyosin structure organization GO:0031032 53 0.027
anion transport GO:0006820 38 0.027
nucleoside triphosphate biosynthetic process GO:0009142 2 0.027
actin cytoskeleton organization GO:0030036 63 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
chordate embryonic development GO:0043009 271 0.027
membrane organization GO:0061024 21 0.026
regulation of programmed cell death GO:0043067 101 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
protein metabolic process GO:0019538 183 0.026
cell cycle GO:0007049 93 0.026
alternative mrna splicing via spliceosome GO:0000380 1 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
cytosolic calcium ion transport GO:0060401 3 0.025
mitochondrion organization GO:0007005 4 0.025
regulation of cellular component organization GO:0051128 86 0.025
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.025
cell part morphogenesis GO:0032990 246 0.025
positive regulation of cellular process GO:0048522 201 0.024
inorganic cation transmembrane transport GO:0098662 50 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
cation transmembrane transport GO:0098655 65 0.024
peptide transport GO:0015833 1 0.024
positive regulation of programmed cell death GO:0043068 29 0.024
cellular component movement GO:0006928 335 0.024
heterocycle metabolic process GO:0046483 290 0.024
localization of cell GO:0051674 244 0.023
lipid storage GO:0019915 1 0.023
synaptic vesicle transport GO:0048489 1 0.023
mitochondrial transport GO:0006839 2 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
establishment of synaptic vesicle localization GO:0097480 1 0.023
cell morphogenesis GO:0000902 289 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
ion transmembrane transport GO:0034220 91 0.023
regulation of cell projection assembly GO:0060491 4 0.023
organelle assembly GO:0070925 110 0.023
organic substance transport GO:0071702 58 0.023
protein import GO:0017038 3 0.022
regulation of cell activation GO:0050865 1 0.022
calcium mediated signaling GO:0019722 2 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
neuromuscular synaptic transmission GO:0007274 2 0.021
cell cycle process GO:0022402 53 0.021
regulation of protein polymerization GO:0032271 2 0.021
cell substrate adhesion GO:0031589 4 0.021
regulation of protein transport GO:0051223 3 0.021
regulation of metal ion transport GO:0010959 4 0.021
action potential GO:0001508 19 0.021
organelle localization GO:0051640 49 0.021
amine metabolic process GO:0009308 2 0.021
ribose phosphate biosynthetic process GO:0046390 20 0.021
sequestering of calcium ion GO:0051208 3 0.020
oxidation reduction process GO:0055114 41 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
nucleoside biosynthetic process GO:0009163 2 0.020
positive regulation of striated muscle cell differentiation GO:0051155 1 0.020
response to stress GO:0006950 263 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
protein import into nucleus GO:0006606 3 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of membrane potential GO:0042391 23 0.020
growth GO:0040007 174 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.019
multicellular organismal metabolic process GO:0044236 2 0.019
regulation of calcium ion transport GO:0051924 2 0.019
adult behavior GO:0030534 2 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.019
regulation of molecular function GO:0065009 70 0.019
response to glucose GO:0009749 3 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.019
b cell activation GO:0042113 2 0.019
cellular localization GO:0051641 97 0.019
release of sequestered calcium ion into cytosol GO:0051209 3 0.019
monovalent inorganic cation transport GO:0015672 42 0.018
regulation of receptor activity GO:0010469 2 0.018
potassium ion transport GO:0006813 10 0.018
multicellular organismal response to stress GO:0033555 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
establishment of organelle localization GO:0051656 45 0.018
gliogenesis GO:0042063 45 0.018
purine ribonucleoside biosynthetic process GO:0046129 2 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.017
negative regulation of protein transport GO:0051224 3 0.017
regulation of hormone secretion GO:0046883 2 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
biosynthetic process GO:0009058 294 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
cell death GO:0008219 121 0.017
macromolecule modification GO:0043412 111 0.017
regulation of membrane repolarization GO:0060306 1 0.017
actin filament polymerization GO:0030041 2 0.017
mitotic cell cycle GO:0000278 64 0.017
regulation of signal transduction GO:0009966 225 0.017
cell projection assembly GO:0030031 64 0.017
response to hexose GO:0009746 3 0.017
cellular protein modification process GO:0006464 100 0.017
meiotic nuclear division GO:0007126 4 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
vasculature development GO:0001944 278 0.017
cell aging GO:0007569 2 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
cation transport GO:0006812 81 0.016
signal transduction GO:0007165 455 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
hormone secretion GO:0046879 2 0.016
regulation of protein complex assembly GO:0043254 3 0.016
actin filament based process GO:0030029 64 0.016
response to carbohydrate GO:0009743 3 0.016
single organism biosynthetic process GO:0044711 71 0.016
regulation of circadian rhythm GO:0042752 4 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
regulation of metabolic process GO:0019222 359 0.016
determination of bilateral symmetry GO:0009855 204 0.015
homeostatic process GO:0042592 142 0.015
lymphocyte proliferation GO:0046651 1 0.015
regulation of glial cell differentiation GO:0045685 4 0.015
carbohydrate derivative biosynthetic process GO:1901137 43 0.015
programmed cell death GO:0012501 119 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
response to fluid shear stress GO:0034405 2 0.015
purine containing compound metabolic process GO:0072521 29 0.015
protein modification process GO:0036211 100 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
phagocytosis GO:0006909 3 0.015
single organism nuclear import GO:1902593 3 0.015
apoptotic process GO:0006915 116 0.014
protein homooligomerization GO:0051260 3 0.014
embryonic heart tube development GO:0035050 133 0.014
regulation of cell communication GO:0010646 232 0.014
angiogenesis GO:0001525 158 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
cellular response to external stimulus GO:0071496 2 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
regulation of response to stimulus GO:0048583 269 0.014
inorganic ion transmembrane transport GO:0098660 57 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
central nervous system development GO:0007417 387 0.014
nucleobase containing compound transport GO:0015931 2 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
regulation of apoptotic process GO:0042981 98 0.014
protein polymerization GO:0051258 4 0.014
behavior GO:0007610 74 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
positive regulation of catabolic process GO:0009896 4 0.014
macromolecular complex disassembly GO:0032984 1 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
single organism carbohydrate metabolic process GO:0044723 12 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
cellular component disassembly GO:0022411 1 0.014
heterocycle biosynthetic process GO:0018130 215 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
cell matrix adhesion GO:0007160 4 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
mononuclear cell proliferation GO:0032943 1 0.013
astrocyte differentiation GO:0048708 1 0.013
positive regulation of translation GO:0045727 1 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
regulation of binding GO:0051098 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
neuron development GO:0048666 262 0.013
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
nucleotide metabolic process GO:0009117 28 0.013
cell projection organization GO:0030030 284 0.013
rna metabolic process GO:0016070 219 0.013
atp catabolic process GO:0006200 4 0.013
hard palate development GO:0060022 4 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
neurological system process GO:0050877 62 0.012
regulation of protein targeting GO:1903533 2 0.012
myotube differentiation GO:0014902 45 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
purine containing compound biosynthetic process GO:0072522 20 0.012
regulation of mrna processing GO:0050684 3 0.012
taxis GO:0042330 109 0.012
meiotic chromosome segregation GO:0045132 3 0.012
hormone transport GO:0009914 2 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
response to monosaccharide GO:0034284 3 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
cellular protein catabolic process GO:0044257 4 0.012
nucleic acid metabolic process GO:0090304 244 0.012
regulation of protein depolymerization GO:1901879 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
regulation of cysteine type endopeptidase activity GO:2000116 21 0.012
death GO:0016265 121 0.012
axonogenesis GO:0007409 152 0.012
specification of symmetry GO:0009799 204 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
multicellular organismal signaling GO:0035637 22 0.012
phosphorus metabolic process GO:0006793 109 0.012
developmental growth GO:0048589 166 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
nucleic acid transport GO:0050657 2 0.012
protein localization to nucleus GO:0034504 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of localization GO:0032879 104 0.011
astral microtubule organization GO:0030953 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
cilium morphogenesis GO:0060271 85 0.011
response to drug GO:0042493 3 0.011
small molecule catabolic process GO:0044282 3 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
negative regulation of cell death GO:0060548 60 0.011
protein secretion GO:0009306 1 0.011
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.011
lipid homeostasis GO:0055088 3 0.011
organophosphate metabolic process GO:0019637 37 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
transmission of nerve impulse GO:0019226 19 0.011
glucose homeostasis GO:0042593 1 0.011
multicellular organism reproduction GO:0032504 35 0.011
zymogen activation GO:0031638 3 0.011
multicellular organism growth GO:0035264 4 0.011
growth plate cartilage morphogenesis GO:0003422 1 0.011
chemotaxis GO:0006935 104 0.011
heart looping GO:0001947 94 0.011
regulation of filopodium assembly GO:0051489 2 0.011
neuroblast proliferation GO:0007405 2 0.011
nucleoside phosphate biosynthetic process GO:1901293 21 0.011
organelle fusion GO:0048284 3 0.011
protein stabilization GO:0050821 2 0.011
regulation of blood pressure GO:0008217 1 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of sodium ion transmembrane transport GO:1902305 1 0.010
negative regulation of molecular function GO:0044092 23 0.010
protein targeting to nucleus GO:0044744 3 0.010
cognition GO:0050890 1 0.010
nucleic acid templated transcription GO:0097659 181 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
tube morphogenesis GO:0035239 349 0.010
hemopoiesis GO:0030097 183 0.010
single fertilization GO:0007338 3 0.010
cellular response to nutrient levels GO:0031669 2 0.010

mdh1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.011
disease of metabolism DOID:0014667 0 0.010