Danio rerio

0 known processes

acta2

actin, alpha 2, smooth muscle, aorta

(Aliases: wu:fb63d03)

acta2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic heart tube morphogenesis GO:0003143 108 0.497
digestive tract morphogenesis GO:0048546 231 0.413
heart development GO:0007507 313 0.388
Zebrafish
embryonic organ development GO:0048568 381 0.322
Zebrafish
determination of left right symmetry GO:0007368 179 0.255
heart morphogenesis GO:0003007 156 0.175
Zebrafish
locomotion GO:0040011 313 0.173
negative regulation of cellular process GO:0048523 283 0.156
regulation of response to stimulus GO:0048583 269 0.152
maintenance of location GO:0051235 4 0.149
signal transduction GO:0007165 455 0.147
intracellular receptor signaling pathway GO:0030522 30 0.137
aging GO:0007568 2 0.135
wound healing GO:0042060 90 0.134
determination of bilateral symmetry GO:0009855 204 0.130
positive regulation of transport GO:0051050 2 0.129
determination of heart left right asymmetry GO:0061371 117 0.128
cell migration GO:0016477 237 0.120
morphogenesis of an epithelium GO:0002009 333 0.117
cytokinesis GO:0000910 3 0.106
heart looping GO:0001947 94 0.099
regulation of biological quality GO:0065008 263 0.098
Mouse
polarized epithelial cell differentiation GO:0030859 4 0.097
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.093
pathway restricted smad protein phosphorylation GO:0060389 1 0.092
embryonic heart tube development GO:0035050 133 0.089
Zebrafish
blood vessel endothelial cell migration GO:0043534 18 0.089
cardiac muscle fiber development GO:0048739 3 0.087
purine nucleoside monophosphate catabolic process GO:0009128 4 0.080
phosphate containing compound metabolic process GO:0006796 108 0.079
cell motility GO:0048870 244 0.077
digestive tract development GO:0048565 265 0.076
regulation of localization GO:0032879 104 0.074
regulation of ectoderm development GO:2000383 2 0.067
regulation of transmembrane transporter activity GO:0022898 2 0.064
regionalization GO:0003002 274 0.064
membrane repolarization GO:0086009 2 0.063
response to stress GO:0006950 263 0.059
response to nutrient GO:0007584 3 0.058
single organism metabolic process GO:0044710 217 0.057
chordate embryonic development GO:0043009 271 0.057
epithelial cell differentiation GO:0030855 116 0.056
Human
angiogenesis GO:0001525 158 0.052
lipid storage GO:0019915 1 0.052
organic acid metabolic process GO:0006082 31 0.052
somitogenesis GO:0001756 87 0.051
tube morphogenesis GO:0035239 349 0.050
blood vessel morphogenesis GO:0048514 216 0.048
muscle fiber development GO:0048747 52 0.048
eye development GO:0001654 277 0.048
transport GO:0006810 220 0.047
retina morphogenesis in camera type eye GO:0060042 79 0.047
cellular component assembly involved in morphogenesis GO:0010927 107 0.047
specification of symmetry GO:0009799 204 0.047
trabecula formation GO:0060343 2 0.045
regulation of cell migration GO:0030334 40 0.044
blood vessel development GO:0001568 246 0.043
Human
cell projection assembly GO:0030031 64 0.042
regulation of signaling GO:0023051 235 0.042
regeneration GO:0031099 91 0.040
tissue regeneration GO:0042246 74 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
protein metabolic process GO:0019538 183 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
response to vitamin b3 GO:0033552 2 0.038
oxoacid metabolic process GO:0043436 31 0.038
anterior posterior pattern specification GO:0009952 152 0.037
lipid digestion GO:0044241 3 0.037
modification dependent macromolecule catabolic process GO:0043632 3 0.036
trabecula morphogenesis GO:0061383 2 0.035
regulation of heart growth GO:0060420 2 0.035
astrocyte differentiation GO:0048708 1 0.035
adherens junction organization GO:0034332 4 0.033
sensory organ development GO:0007423 393 0.033
regulation of metabolic process GO:0019222 359 0.032
ameboidal type cell migration GO:0001667 143 0.032
dorsal convergence GO:0060030 14 0.032
localization of cell GO:0051674 244 0.032
proepicardium development GO:0003342 4 0.032
myeloid cell development GO:0061515 32 0.031
cell projection organization GO:0030030 284 0.031
convergent extension involved in gastrulation GO:0060027 71 0.031
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.031
immune response GO:0006955 28 0.030
behavior GO:0007610 74 0.030
response to corticosteroid GO:0031960 1 0.030
cell morphogenesis GO:0000902 289 0.029
striated muscle tissue development GO:0014706 110 0.029
cellular response to growth factor stimulus GO:0071363 39 0.029
cardiac atrium development GO:0003230 4 0.029
cellular component movement GO:0006928 335 0.029
cardiac chamber development GO:0003205 19 0.029
cell aging GO:0007569 2 0.029
regulation of protein depolymerization GO:1901879 1 0.029
cellular protein catabolic process GO:0044257 4 0.028
odontogenesis of dentin containing tooth GO:0042475 1 0.028
muscle system process GO:0003012 20 0.027
Mouse
phagocytosis GO:0006909 3 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.027
cellular potassium ion transport GO:0071804 10 0.027
organelle assembly GO:0070925 110 0.026
phosphorus metabolic process GO:0006793 109 0.026
regulation of locomotion GO:0040012 55 0.026
regulation of cell shape GO:0008360 1 0.026
digestive system development GO:0055123 289 0.026
camera type eye development GO:0043010 222 0.025
positive regulation of cellular process GO:0048522 201 0.025
sensory system development GO:0048880 76 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
gastrulation GO:0007369 208 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.025
ion transmembrane transport GO:0034220 91 0.025
striated muscle cell development GO:0055002 108 0.024
cardiac atrium morphogenesis GO:0003209 2 0.024
striated muscle cell differentiation GO:0051146 129 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
protein complex subunit organization GO:0071822 46 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
cellular response to nutrient levels GO:0031669 2 0.023
extracellular structure organization GO:0043062 27 0.023
regulation of behavior GO:0050795 24 0.023
actin cytoskeleton organization GO:0030036 63 0.023
cardiac chamber morphogenesis GO:0003206 12 0.022
regulation of protein metabolic process GO:0051246 56 0.022
axis elongation involved in somitogenesis GO:0090245 2 0.022
cellular component biogenesis GO:0044085 178 0.022
larval development GO:0002164 2 0.022
regulation of cell communication GO:0010646 232 0.022
heterocycle metabolic process GO:0046483 290 0.022
reactive oxygen species biosynthetic process GO:1903409 1 0.022
endocardial cushion formation GO:0003272 2 0.022
Zebrafish
modification dependent protein catabolic process GO:0019941 3 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
cell substrate adhesion GO:0031589 4 0.021
response to ketone GO:1901654 1 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
response to vitamin GO:0033273 3 0.021
intracellular signal transduction GO:0035556 85 0.021
muscle tissue development GO:0060537 110 0.021
stem cell proliferation GO:0072089 4 0.021
actin filament based movement GO:0030048 1 0.021
mesendoderm migration GO:0090133 2 0.021
endocardial cushion development GO:0003197 6 0.021
Zebrafish
pigmentation GO:0043473 85 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
response to glucocorticoid GO:0051384 1 0.021
cellular response to external stimulus GO:0071496 2 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
cellular lipid metabolic process GO:0044255 36 0.020
response to external stimulus GO:0009605 264 0.020
Human
regulation of cell motility GO:2000145 46 0.020
retinal metabolic process GO:0042574 3 0.020
lateral line system development GO:0048925 76 0.019
hormone secretion GO:0046879 2 0.019
negative regulation of heart contraction GO:0045822 2 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
proteasomal protein catabolic process GO:0010498 2 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
endocardial cushion morphogenesis GO:0003203 3 0.018
Zebrafish
neural crest cell differentiation GO:0014033 72 0.018
ectoderm formation GO:0001705 2 0.018
regulation of wound healing GO:0061041 2 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
brain development GO:0007420 293 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
somite development GO:0061053 96 0.018
atp catabolic process GO:0006200 4 0.018
muscle cell differentiation GO:0042692 139 0.018
positive regulation of immune system process GO:0002684 17 0.018
venous blood vessel development GO:0060841 9 0.018
oogenesis GO:0048477 14 0.017
cell cycle arrest GO:0007050 1 0.017
cellular aldehyde metabolic process GO:0006081 4 0.017
endocrine hormone secretion GO:0060986 2 0.017
circulatory system process GO:0003013 87 0.017
Mouse
multi organism process GO:0051704 134 0.017
Human
cardiac muscle cell development GO:0055013 20 0.017
positive regulation of endothelial cell proliferation GO:0001938 1 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
diterpenoid metabolic process GO:0016101 15 0.017
skeletal muscle organ development GO:0060538 78 0.017
lateral line development GO:0048882 66 0.017
single organism transport GO:0044765 206 0.017
retinoic acid receptor signaling pathway GO:0048384 16 0.017
response to mercury ion GO:0046689 1 0.017
pyruvate metabolic process GO:0006090 1 0.017
skeletal muscle tissue development GO:0007519 67 0.017
skeletal muscle fiber development GO:0048741 35 0.017
muscle organ development GO:0007517 101 0.016
bmp signaling pathway GO:0030509 52 0.016
multicellular organismal signaling GO:0035637 22 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
signal transduction by phosphorylation GO:0023014 18 0.016
regulation of membrane potential GO:0042391 23 0.016
tissue remodeling GO:0048771 4 0.016
cellular protein metabolic process GO:0044267 129 0.016
regulation of cell projection assembly GO:0060491 4 0.016
lymphoid lineage cell migration into thymus GO:0097535 4 0.016
myotube differentiation GO:0014902 45 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.016
cellular response to oxygen levels GO:0071453 1 0.016
immune system development GO:0002520 191 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cell substrate junction assembly GO:0007044 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
nucleoside biosynthetic process GO:0009163 2 0.015
mesoderm morphogenesis GO:0048332 51 0.015
epiboly GO:0090504 41 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
negative regulation of innate immune response GO:0045824 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
response to fatty acid GO:0070542 5 0.015
negative regulation of kinase activity GO:0033673 4 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
gene expression GO:0010467 252 0.015
glomerulus vasculature development GO:0072012 2 0.015
Human
apoptotic process involved in development GO:1902742 2 0.015
membrane hyperpolarization GO:0060081 1 0.014
regulation of binding GO:0051098 3 0.014
positive regulation of protein kinase b signaling GO:0051897 1 0.014
cellular amine metabolic process GO:0044106 2 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
cellular ketone metabolic process GO:0042180 11 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
cell part morphogenesis GO:0032990 246 0.014
hormone transport GO:0009914 2 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
regulation of cardiac muscle tissue development GO:0055024 1 0.014
regulation of ectodermal cell fate specification GO:0042665 2 0.014
interspecies interaction between organisms GO:0044419 4 0.013
positive regulation of muscle tissue development GO:1901863 1 0.013
small molecule metabolic process GO:0044281 77 0.013
actin filament based process GO:0030029 64 0.013
mitochondrion organization GO:0007005 4 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
regulation of cell cycle GO:0051726 52 0.013
epithelium migration GO:0090132 25 0.013
glial cell migration GO:0008347 3 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
cardiac muscle cell differentiation GO:0055007 30 0.013
rhodopsin mediated signaling pathway GO:0016056 1 0.013
taxis GO:0042330 109 0.013
innate immune response GO:0045087 13 0.013
segmentation GO:0035282 97 0.013
response to carbohydrate GO:0009743 3 0.013
response to prostaglandin GO:0034694 5 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of translation GO:0045727 1 0.012
osteoclast differentiation GO:0030316 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
Mouse
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.012
optic placode formation involved in camera type eye formation GO:0046619 3 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
negative regulation of biological process GO:0048519 304 0.012
regulation of bone mineralization GO:0030500 2 0.012
single organism localization GO:1902578 225 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
cellular response to unfolded protein GO:0034620 2 0.011
response to monosaccharide GO:0034284 3 0.011
ovulation cycle GO:0042698 2 0.011
extracellular matrix organization GO:0030198 27 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
calcium mediated signaling GO:0019722 2 0.011
establishment of apical basal cell polarity GO:0035089 2 0.011
osteoclast development GO:0036035 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
response to wounding GO:0009611 116 0.011
lipid metabolic process GO:0006629 52 0.011
cellular response to starvation GO:0009267 1 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
response to external biotic stimulus GO:0043207 97 0.011
Human
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
sensory organ morphogenesis GO:0090596 200 0.011
system process GO:0003008 185 0.011
Mouse
actin mediated cell contraction GO:0070252 1 0.011
regulation of hormone secretion GO:0046883 2 0.011
epithelial cell development GO:0002064 42 0.011
Human
lymphoid lineage cell migration GO:0097534 4 0.011
left right pattern formation GO:0060972 19 0.011
cardiac ventricle development GO:0003231 9 0.011
regulation of peptidase activity GO:0052547 23 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of eye photoreceptor cell development GO:0042478 2 0.011
cellular component assembly GO:0022607 170 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
muscle contraction GO:0006936 18 0.011
Mouse
oxidoreduction coenzyme metabolic process GO:0006733 1 0.011
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.010
muscle cell development GO:0055001 115 0.010
g2 m transition of mitotic cell cycle GO:0000086 4 0.010
phosphorylation GO:0016310 69 0.010
regulation of myotube differentiation GO:0010830 2 0.010
female gonad development GO:0008585 4 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
camera type eye morphogenesis GO:0048593 108 0.010
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.010
immune system process GO:0002376 241 0.010
small molecule catabolic process GO:0044282 3 0.010
response to glucose GO:0009749 3 0.010
regulation of cell activation GO:0050865 1 0.010
female sex differentiation GO:0046660 4 0.010
transmembrane transport GO:0055085 120 0.010
mesoderm development GO:0007498 88 0.010
locomotor rhythm GO:0045475 3 0.010
regulation of mapk cascade GO:0043408 14 0.010
forebrain development GO:0030900 96 0.010

acta2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.076
muscular disease DOID:0080000 0 0.076
disease of anatomical entity DOID:7 0 0.076
Human
musculoskeletal system disease DOID:17 0 0.076
muscle tissue disease DOID:66 0 0.076
heart disease DOID:114 0 0.071
cardiomyopathy DOID:0050700 0 0.071
intrinsic cardiomyopathy DOID:0060036 0 0.071
cardiovascular system disease DOID:1287 0 0.071
Human
disease of metabolism DOID:0014667 0 0.050