Danio rerio

0 known processes

speg

SPEG complex locus

(Aliases: im:6912258,wu:fc31c10,fc31c10,apeg1)

speg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.076
nitrogen compound metabolic process GO:0006807 319 0.068
Worm
aging GO:0007568 2 0.060
cellular biosynthetic process GO:0044249 286 0.056
response to chemical GO:0042221 320 0.054
embryonic organ development GO:0048568 381 0.053
regulation of cellular metabolic process GO:0031323 320 0.052
Worm
maintenance of location GO:0051235 4 0.052
rna metabolic process GO:0016070 219 0.050
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
Worm
cellular macromolecule metabolic process GO:0044260 391 0.048
signal transduction GO:0007165 455 0.047
cellular nitrogen compound metabolic process GO:0034641 290 0.046
Worm
meiotic nuclear division GO:0007126 4 0.045
specification of symmetry GO:0009799 204 0.044
response to organic substance GO:0010033 153 0.044
regulation of multicellular organism growth GO:0040014 4 0.044
organic cyclic compound metabolic process GO:1901360 301 0.042
Worm
amine metabolic process GO:0009308 2 0.041
phagocytosis GO:0006909 3 0.041
biosynthetic process GO:0009058 294 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
regulation of primary metabolic process GO:0080090 311 0.040
Worm
tube morphogenesis GO:0035239 349 0.039
cellular ketone metabolic process GO:0042180 11 0.039
embryonic organ morphogenesis GO:0048562 274 0.039
gene expression GO:0010467 252 0.038
heterocycle metabolic process GO:0046483 290 0.038
Worm
positive regulation of transport GO:0051050 2 0.038
heterocycle biosynthetic process GO:0018130 215 0.037
regulation of response to stimulus GO:0048583 269 0.037
Worm
morphogenesis of an epithelium GO:0002009 333 0.037
determination of left right symmetry GO:0007368 179 0.037
aromatic compound biosynthetic process GO:0019438 217 0.036
determination of bilateral symmetry GO:0009855 204 0.035
eye development GO:0001654 277 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.035
gland development GO:0048732 143 0.035
lipid storage GO:0019915 1 0.035
multicellular organism growth GO:0035264 4 0.035
organic substance biosynthetic process GO:1901576 289 0.034
cellular component movement GO:0006928 335 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.034
cellular amine metabolic process GO:0044106 2 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
protein localization to plasma membrane GO:0072659 1 0.031
organic acid metabolic process GO:0006082 31 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
Worm
regulation of biological quality GO:0065008 263 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
Worm
cell surface receptor signaling pathway GO:0007166 325 0.031
stem cell maintenance GO:0019827 4 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
regulation of cell communication GO:0010646 232 0.030
Worm
regulation of multicellular organismal process GO:0051239 277 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
Worm
regulation of reproductive process GO:2000241 4 0.030
regulation of dendrite development GO:0050773 3 0.030
regulation of meiotic cell cycle GO:0051445 1 0.029
sensory organ development GO:0007423 393 0.029
positive regulation of cellular process GO:0048522 201 0.029
Worm
carboxylic acid metabolic process GO:0019752 22 0.029
regulation of metabolic process GO:0019222 359 0.029
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
regulation of biosynthetic process GO:0009889 250 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
single organism metabolic process GO:0044710 217 0.028
Worm
regulation of gene expression GO:0010468 265 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
nucleic acid metabolic process GO:0090304 244 0.028
regulation of developmental process GO:0050793 247 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
oxoacid metabolic process GO:0043436 31 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
cell migration GO:0016477 237 0.027
positive regulation of immune effector process GO:0002699 3 0.026
neuron differentiation GO:0030182 353 0.026
response to carbohydrate GO:0009743 3 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
camera type eye development GO:0043010 222 0.026
regulation of rna metabolic process GO:0051252 224 0.026
muscle cell differentiation GO:0042692 139 0.026
Mouse Rat Worm
small molecule metabolic process GO:0044281 77 0.026
Worm
localization of cell GO:0051674 244 0.026
cognition GO:0050890 1 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
Worm
cell morphogenesis GO:0000902 289 0.025
regulation of signal transduction GO:0009966 225 0.024
Worm
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.024
rna biosynthetic process GO:0032774 181 0.024
positive regulation of metabolic process GO:0009893 108 0.024
Worm
sleep GO:0030431 1 0.024
generation of neurons GO:0048699 385 0.024
cell motility GO:0048870 244 0.024
phosphorus metabolic process GO:0006793 109 0.024
Worm
neurotransmitter transport GO:0006836 2 0.024
regulation of cytokine production GO:0001817 3 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
Worm
response to hexose GO:0009746 3 0.024
muscle structure development GO:0061061 196 0.023
Mouse Rat Worm
negative regulation of biological process GO:0048519 304 0.023
response to monosaccharide GO:0034284 3 0.023
response to stress GO:0006950 263 0.023
glucose homeostasis GO:0042593 1 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.023
lipid catabolic process GO:0016042 4 0.022
cellular response to external stimulus GO:0071496 2 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
central nervous system development GO:0007417 387 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
gastrulation GO:0007369 208 0.021
mesenchyme development GO:0060485 127 0.021
digestive tract development GO:0048565 265 0.021
positive regulation of biological process GO:0048518 253 0.021
Worm
chordate embryonic development GO:0043009 271 0.021
Mouse
cell projection morphogenesis GO:0048858 244 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
regulation of mrna processing GO:0050684 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
sensory organ morphogenesis GO:0090596 200 0.021
response to external stimulus GO:0009605 264 0.021
heart development GO:0007507 313 0.021
Mouse
transcription dna templated GO:0006351 181 0.020
positive regulation of catabolic process GO:0009896 4 0.020
Worm
epithelial tube morphogenesis GO:0060562 148 0.020
negative regulation of cellular process GO:0048523 283 0.020
positive regulation of cell cycle GO:0045787 3 0.020
regulation of signaling GO:0023051 235 0.020
Worm
guanosine containing compound metabolic process GO:1901068 4 0.020
Worm
embryonic heart tube development GO:0035050 133 0.020
membrane fusion GO:0061025 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.019
meiotic cell cycle process GO:1903046 3 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
Worm
nucleic acid templated transcription GO:0097659 181 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of circadian rhythm GO:0042752 4 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
vasculature development GO:0001944 278 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
pancreas development GO:0031016 84 0.019
response to drug GO:0042493 3 0.019
regulation of blood pressure GO:0008217 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.018
peptidyl serine modification GO:0018209 2 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
system process GO:0003008 185 0.018
fertilization GO:0009566 3 0.018
stem cell differentiation GO:0048863 117 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
spermatid differentiation GO:0048515 2 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
protein localization to nucleus GO:0034504 3 0.018
spermatid development GO:0007286 2 0.018
somatic muscle development GO:0007525 4 0.018
homeostatic process GO:0042592 142 0.018
locomotion GO:0040011 313 0.018
Worm
cellular protein catabolic process GO:0044257 4 0.018
stem cell proliferation GO:0072089 4 0.018
golgi vesicle transport GO:0048193 3 0.018
cartilage development GO:0051216 96 0.017
carbohydrate homeostasis GO:0033500 1 0.017
regulation of inflammatory response GO:0050727 2 0.017
response to glucose GO:0009749 3 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of systemic arterial blood pressure GO:0003073 1 0.017
adult behavior GO:0030534 2 0.017
hepaticobiliary system development GO:0061008 98 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
cell substrate adhesion GO:0031589 4 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
regulation of transcription dna templated GO:0006355 213 0.017
regulation of tube size GO:0035150 2 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of dendrite morphogenesis GO:0048814 3 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
chemotaxis GO:0006935 104 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
Mouse
regulation of cell differentiation GO:0045595 142 0.016
locomotor rhythm GO:0045475 3 0.016
germ line stem cell maintenance GO:0030718 2 0.016
nuclear transport GO:0051169 4 0.016
developmental growth GO:0048589 166 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
Worm
digestive system development GO:0055123 289 0.016
single organism nuclear import GO:1902593 3 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
regulation of cell activation GO:0050865 1 0.016
synaptic vesicle localization GO:0097479 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
brain development GO:0007420 293 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
blood vessel development GO:0001568 246 0.016
interspecies interaction between organisms GO:0044419 4 0.016
skeletal system development GO:0001501 181 0.016
cellular response to starvation GO:0009267 1 0.016
neuron development GO:0048666 262 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
gtp metabolic process GO:0046039 4 0.016
Worm
g protein coupled receptor signaling pathway GO:0007186 74 0.016
cellular component morphogenesis GO:0032989 336 0.016
Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
immune system development GO:0002520 191 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cell projection organization GO:0030030 284 0.015
immune system process GO:0002376 241 0.015
regulation of binding GO:0051098 3 0.015
positive regulation of secretion GO:0051047 1 0.015
endocrine system development GO:0035270 65 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
protein import GO:0017038 3 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
gtp catabolic process GO:0006184 2 0.015
Worm
regionalization GO:0003002 274 0.015
tissue remodeling GO:0048771 4 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
cellular lipid catabolic process GO:0044242 3 0.015
cell part morphogenesis GO:0032990 246 0.015
neurotransmitter secretion GO:0007269 2 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
female sex differentiation GO:0046660 4 0.015
positive regulation of cell activation GO:0050867 1 0.014
small molecule catabolic process GO:0044282 3 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
phagocytosis engulfment GO:0006911 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
digestive tract morphogenesis GO:0048546 231 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
nuclear export GO:0051168 1 0.014
hemopoiesis GO:0030097 183 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
cellular response to organic substance GO:0071310 105 0.014
dicarboxylic acid transport GO:0006835 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
liver development GO:0001889 96 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
notochord development GO:0030903 54 0.014
multi organism process GO:0051704 134 0.014
eye morphogenesis GO:0048592 144 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
synaptic vesicle transport GO:0048489 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
cellular protein metabolic process GO:0044267 129 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
neuron projection development GO:0031175 180 0.013
antimicrobial humoral response GO:0019730 2 0.013
organelle organization GO:0006996 227 0.013
Worm
autophagy GO:0006914 4 0.013
mitochondrion organization GO:0007005 4 0.013
compound eye development GO:0048749 2 0.013
regulation of dna replication GO:0006275 3 0.013
intracellular signal transduction GO:0035556 85 0.013
single organism organelle organization GO:1902589 199 0.013
Worm
dorsal ventral pattern formation GO:0009953 125 0.013
nuclear import GO:0051170 3 0.013
regulation of synapse organization GO:0050807 3 0.013
angiogenesis GO:0001525 158 0.013
axon development GO:0061564 166 0.013
growth GO:0040007 174 0.013
regulation of transporter activity GO:0032409 2 0.013
macromolecule modification GO:0043412 111 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
Worm
regulation of cell projection assembly GO:0060491 4 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
Worm
protein targeting to nucleus GO:0044744 3 0.013
neuroblast proliferation GO:0007405 2 0.013
positive regulation of camp biosynthetic process GO:0030819 2 0.013
membrane invagination GO:0010324 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
mesenchymal cell development GO:0014031 78 0.013
protein import into nucleus GO:0006606 3 0.013
ear development GO:0043583 127 0.013
heart morphogenesis GO:0003007 156 0.013
cellular amide metabolic process GO:0043603 4 0.013
regulation of blood vessel size GO:0050880 2 0.013
hormone secretion GO:0046879 2 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
renal system development GO:0072001 94 0.013
secondary metabolic process GO:0019748 3 0.013
female gonad development GO:0008585 4 0.013
blood vessel morphogenesis GO:0048514 216 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
Worm
taxis GO:0042330 109 0.012
glial cell migration GO:0008347 3 0.012
regulation of cell development GO:0060284 100 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
cellular component assembly GO:0022607 170 0.012
Worm
internal protein amino acid acetylation GO:0006475 2 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of cellular component organization GO:0051128 86 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of protein targeting GO:1903533 2 0.012
hatching GO:0035188 4 0.012
blood circulation GO:0008015 87 0.012
fin development GO:0033333 77 0.012
hormone transport GO:0009914 2 0.012
atp catabolic process GO:0006200 4 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
cellular response to hypoxia GO:0071456 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
Worm
response to wounding GO:0009611 116 0.012
startle response GO:0001964 4 0.012
regulation of jak stat cascade GO:0046425 3 0.012
heart looping GO:0001947 94 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
adherens junction organization GO:0034332 4 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
mesoderm development GO:0007498 88 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
peptide transport GO:0015833 1 0.012
gas transport GO:0015669 3 0.012
stem cell development GO:0048864 82 0.011
chemosensory behavior GO:0007635 1 0.011
inner ear development GO:0048839 126 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of muscle contraction GO:0006937 3 0.011
negative regulation of signal transduction GO:0009968 94 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
negative regulation of catabolic process GO:0009895 3 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
protein metabolic process GO:0019538 183 0.011
transport GO:0006810 220 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
lipid homeostasis GO:0055088 3 0.011
protein acetylation GO:0006473 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
response to external biotic stimulus GO:0043207 97 0.011
meiotic chromosome segregation GO:0045132 3 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
single organism localization GO:1902578 225 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
response to lipid GO:0033993 60 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
response to vitamin GO:0033273 3 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
directional locomotion GO:0033058 1 0.011
phosphorylation GO:0016310 69 0.011
water homeostasis GO:0030104 4 0.011
protein modification process GO:0036211 100 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
negative regulation of signaling GO:0023057 96 0.010
regulation of wound healing GO:0061041 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
rna localization GO:0006403 4 0.010
response to biotic stimulus GO:0009607 97 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
regulation of endocrine process GO:0044060 2 0.010
cell killing GO:0001906 2 0.010
b cell activation GO:0042113 2 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
negative regulation of metabolic process GO:0009892 86 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
regulation of protein complex assembly GO:0043254 3 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
single organism biosynthetic process GO:0044711 71 0.010
regulation of localization GO:0032879 104 0.010
death GO:0016265 121 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
Worm
inositol lipid mediated signaling GO:0048017 2 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
single organism membrane fusion GO:0044801 2 0.010
hindbrain development GO:0030902 91 0.010
response to endogenous stimulus GO:0009719 83 0.010
positive regulation of reproductive process GO:2000243 2 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
Worm
axon guidance GO:0007411 86 0.010

speg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
Human
musculoskeletal system disease DOID:17 0 0.012
Human
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.011