Danio rerio

13 known processes

lbx2

ladybird homeobox homolog 2 (Drosophila)

(Aliases: lbx1h,zgc:92170,homeobox,lbx,lbx1,SI:zC207O21.2,wu:fc26c12,fc26c12)

lbx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal muscle tissue development GO:0007519 67 0.524
Fly
skeletal muscle organ development GO:0060538 78 0.380
Fly
somatic muscle development GO:0007525 4 0.304
posterior lateral line system development GO:0048915 46 0.261
muscle structure development GO:0061061 196 0.222
skin development GO:0043588 54 0.167
Fly
myotube differentiation GO:0014902 45 0.150
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.141
embryonic organ morphogenesis GO:0048562 274 0.140
skeletal muscle thin filament assembly GO:0030240 4 0.123
mechanosensory lateral line system development GO:0048881 49 0.118
post embryonic organ development GO:0048569 4 0.117
Fly
embryonic limb morphogenesis GO:0030326 2 0.117
posterior lateral line development GO:0048916 38 0.115
negative regulation of biological process GO:0048519 304 0.115
Fly
cellular component morphogenesis GO:0032989 336 0.114
Fly
mesenchyme development GO:0060485 127 0.114
tube morphogenesis GO:0035239 349 0.113
multicellular organismal signaling GO:0035637 22 0.108
inner ear development GO:0048839 126 0.096
nitrogen compound metabolic process GO:0006807 319 0.096
Fly
somite specification GO:0001757 12 0.086
lateral line development GO:0048882 66 0.085
cellular nitrogen compound biosynthetic process GO:0044271 218 0.078
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.071
Fly
striated muscle cell differentiation GO:0051146 129 0.068
Fly
adult behavior GO:0030534 2 0.061
venous blood vessel morphogenesis GO:0048845 3 0.058
facial nerve morphogenesis GO:0021610 1 0.054
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.053
Fly
cardiac muscle fiber development GO:0048739 3 0.052
outflow tract morphogenesis GO:0003151 1 0.052
axonal fasciculation GO:0007413 11 0.051
glial cell migration GO:0008347 3 0.051
immune system process GO:0002376 241 0.050
regulation of gene expression GO:0010468 265 0.050
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.050
Fly
stem cell differentiation GO:0048863 117 0.049
regulation of metabolic process GO:0019222 359 0.047
Fly
lateral line system development GO:0048925 76 0.046
reactive nitrogen species metabolic process GO:2001057 0 0.046
positive regulation of transport GO:0051050 2 0.045
sensory system development GO:0048880 76 0.045
regulation of sarcomere organization GO:0060297 2 0.045
cranial nerve development GO:0021545 42 0.044
syncytium formation GO:0006949 12 0.043
Fly
heart development GO:0007507 313 0.043
voluntary skeletal muscle contraction GO:0003010 4 0.042
regulation of neutrophil migration GO:1902622 6 0.042
single organism organelle organization GO:1902589 199 0.041
ear development GO:0043583 127 0.040
cell migration GO:0016477 237 0.040
Fly
epithelial cell differentiation GO:0030855 116 0.039
actin filament based movement GO:0030048 1 0.039
brain development GO:0007420 293 0.039
syncytium formation by plasma membrane fusion GO:0000768 12 0.039
Fly
morphogenesis of an epithelium GO:0002009 333 0.037
response to stress GO:0006950 263 0.037
single organism membrane fusion GO:0044801 2 0.037
transmission of nerve impulse GO:0019226 19 0.037
semicircular canal development GO:0060872 24 0.036
cranial ganglion development GO:0061550 3 0.036
lymphoid lineage cell migration into thymus GO:0097535 4 0.035
larval development GO:0002164 2 0.035
regulation of developmental process GO:0050793 247 0.034
Fly
neuronal action potential GO:0019228 18 0.034
cell projection organization GO:0030030 284 0.034
Fly
myotome development GO:0061055 1 0.033
striated muscle cell development GO:0055002 108 0.032
regulation of primary metabolic process GO:0080090 311 0.032
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.032
Fly
embryonic organ development GO:0048568 381 0.031
axon regeneration GO:0031103 14 0.031
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.031
epithelial tube morphogenesis GO:0060562 148 0.030
system process GO:0003008 185 0.030
negative regulation of axon guidance GO:1902668 1 0.030
cell morphogenesis GO:0000902 289 0.030
Fly
regulation of cell shape GO:0008360 1 0.030
spermatid differentiation GO:0048515 2 0.030
nitric oxide biosynthetic process GO:0006809 2 0.030
growth GO:0040007 174 0.029
blood vessel development GO:0001568 246 0.028
extraocular skeletal muscle development GO:0002074 3 0.028
response to alkaloid GO:0043279 2 0.027
cartilage condensation GO:0001502 3 0.027
establishment or maintenance of cell polarity GO:0007163 29 0.027
response to axon injury GO:0048678 14 0.027
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.027
regulation of dendrite development GO:0050773 3 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
Fly
skeletal myofibril assembly GO:0014866 7 0.025
regulation of gene expression epigenetic GO:0040029 11 0.025
transcription dna templated GO:0006351 181 0.025
Fly
head development GO:0060322 303 0.025
inositol lipid mediated signaling GO:0048017 2 0.025
negative regulation of metabolic process GO:0009892 86 0.025
Fly
epithelium migration GO:0090132 25 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
Fly
twitch skeletal muscle contraction GO:0014721 4 0.024
muscle organ development GO:0007517 101 0.024
Fly
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
regulation of heart growth GO:0060420 2 0.024
histone h3 k4 methylation GO:0051568 2 0.024
neuron differentiation GO:0030182 353 0.023
Fly
nitric oxide metabolic process GO:0046209 2 0.023
multi organism process GO:0051704 134 0.022
nucleic acid metabolic process GO:0090304 244 0.022
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
regulation of synapse organization GO:0050807 3 0.022
cell aggregation GO:0098743 3 0.022
leukocyte homeostasis GO:0001776 2 0.022
positive regulation of cellular biosynthetic process GO:0031328 68 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
fertilization GO:0009566 3 0.022
olfactory bulb development GO:0021772 4 0.021
lymphoid lineage cell migration GO:0097534 4 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
polarized epithelial cell differentiation GO:0030859 4 0.020
membrane fusion GO:0061025 2 0.020
positive regulation of transcription dna templated GO:0045893 57 0.020
regulation of mrna processing GO:0050684 3 0.020
axon development GO:0061564 166 0.020
negative regulation of muscle tissue development GO:1901862 2 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
Fly
peripheral nervous system development GO:0007422 55 0.019
protein stabilization GO:0050821 2 0.019
myeloid cell homeostasis GO:0002262 56 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
cellular aldehyde metabolic process GO:0006081 4 0.018
somite development GO:0061053 96 0.018
embryonic skeletal joint morphogenesis GO:0060272 3 0.018
proximal distal pattern formation GO:0009954 1 0.018
cell motility GO:0048870 244 0.018
Fly
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
cardiac muscle cell differentiation GO:0055007 30 0.018
regulation of protein catabolic process GO:0042176 1 0.018
segment specification GO:0007379 12 0.018
anatomical structure arrangement GO:0048532 2 0.018
muscle cell development GO:0055001 115 0.018
myofibril assembly GO:0030239 48 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.017
rna biosynthetic process GO:0032774 181 0.017
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
Fly
regulation of cytoskeleton organization GO:0051493 11 0.017
neutrophil homeostasis GO:0001780 1 0.017
mitochondrion organization GO:0007005 4 0.017
myeloid leukocyte migration GO:0097529 12 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
Fly
organic acid metabolic process GO:0006082 31 0.016
response to glucocorticoid GO:0051384 1 0.016
neuroblast differentiation GO:0014016 1 0.016
centrosome organization GO:0051297 1 0.016
regulation of circadian rhythm GO:0042752 4 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
hindbrain development GO:0030902 91 0.016
retinal metabolic process GO:0042574 3 0.015
regulation of localization GO:0032879 104 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
Fly
response to oxygen containing compound GO:1901700 55 0.015
muscle tissue development GO:0060537 110 0.015
Fly
amine metabolic process GO:0009308 2 0.015
digestive system development GO:0055123 289 0.015
pigmentation GO:0043473 85 0.015
positive regulation of cellular process GO:0048522 201 0.015
cell recognition GO:0008037 19 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
embryonic skeletal system development GO:0048706 97 0.015
mesenchymal cell development GO:0014031 78 0.015
cardiocyte differentiation GO:0035051 44 0.015
oxoacid metabolic process GO:0043436 31 0.015
gene expression GO:0010467 252 0.015
Fly
regulation of stem cell differentiation GO:2000736 4 0.014
cell projection morphogenesis GO:0048858 244 0.014
Fly
immune system development GO:0002520 191 0.014
primary neural tube formation GO:0014020 1 0.014
neutrophil migration GO:1990266 10 0.014
forebrain cell migration GO:0021885 1 0.014
digestive tract morphogenesis GO:0048546 231 0.014
response to external stimulus GO:0009605 264 0.014
positive regulation of cell cycle GO:0045787 3 0.014
lamellipodium organization GO:0097581 1 0.014
tissue migration GO:0090130 37 0.014
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.014
regulation of cell development GO:0060284 100 0.014
Fly
retinoic acid metabolic process GO:0042573 9 0.013
regulation of blood vessel size GO:0050880 2 0.013
response to biotic stimulus GO:0009607 97 0.013
maintenance of location GO:0051235 4 0.013
heterocycle metabolic process GO:0046483 290 0.013
Fly
response to activity GO:0014823 14 0.013
regulation of cellular extravasation GO:0002691 1 0.013
branchiomotor neuron axon guidance GO:0021785 1 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
positive regulation of muscle cell differentiation GO:0051149 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
Fly
action potential GO:0001508 19 0.013
sensory organ development GO:0007423 393 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
skeletal muscle fiber development GO:0048741 35 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
neuron migration GO:0001764 22 0.013
cell chemotaxis GO:0060326 17 0.013
regulation of organelle assembly GO:1902115 4 0.013
epidermal cell fate specification GO:0009957 4 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
Fly
cellular amino acid metabolic process GO:0006520 7 0.013
astrocyte differentiation GO:0048708 1 0.013
chemotaxis GO:0006935 104 0.012
cell cycle GO:0007049 93 0.012
appendage development GO:0048736 80 0.012
Fly
neuron projection regeneration GO:0031102 16 0.012
regulation of muscle contraction GO:0006937 3 0.012
multicellular organismal response to stress GO:0033555 2 0.012
regulation of actin cytoskeleton organization GO:0032956 8 0.012
blood vessel morphogenesis GO:0048514 216 0.012
cellular protein catabolic process GO:0044257 4 0.012
biosynthetic process GO:0009058 294 0.012
Fly
response to chemical GO:0042221 320 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
b cell activation GO:0042113 2 0.012
dna biosynthetic process GO:0071897 3 0.012
embryonic viscerocranium morphogenesis GO:0048703 52 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
diterpenoid biosynthetic process GO:0016102 7 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
Fly
atp catabolic process GO:0006200 4 0.011
somitogenesis GO:0001756 87 0.011
skeletal muscle contraction GO:0003009 5 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
Fly
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of neurological system process GO:0031644 2 0.011
cellular macromolecule metabolic process GO:0044260 391 0.011
Fly
meiotic chromosome segregation GO:0045132 3 0.011
microtubule organizing center organization GO:0031023 1 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
pronephros development GO:0048793 69 0.011
morphogenesis of embryonic epithelium GO:0016331 30 0.011
axon ensheathment GO:0008366 18 0.011
regulation of locomotion GO:0040012 55 0.011
response to organic cyclic compound GO:0014070 51 0.011
centrosome cycle GO:0007098 1 0.011
determination of bilateral symmetry GO:0009855 204 0.011
olfactory placode development GO:0071698 12 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
periodic partitioning GO:0007365 1 0.011
epidermis development GO:0008544 48 0.011
Fly
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
sexual reproduction GO:0019953 36 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
regeneration GO:0031099 91 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.010
cardiac muscle myosin thick filament assembly GO:0071690 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
axon ensheathment in central nervous system GO:0032291 2 0.010
regulation of cell projection assembly GO:0060491 4 0.010
response to vitamin GO:0033273 3 0.010
taxis GO:0042330 109 0.010
lipid storage GO:0019915 1 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.010
neuron recognition GO:0008038 18 0.010
single fertilization GO:0007338 3 0.010
negative regulation of neuron projection regeneration GO:0070571 4 0.010
digestive tract development GO:0048565 265 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
Fly

lbx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
bone disease DOID:0080001 0 0.022
musculoskeletal system disease DOID:17 0 0.022
connective tissue disease DOID:65 0 0.022
sensory system disease DOID:0050155 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
auditory system disease DOID:2742 0 0.012
nonsyndromic deafness DOID:0050563 0 0.012