Danio rerio

0 known processes

nfatc4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

(Aliases: si:dkeyp-66d1.4)

nfatc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of response to stimulus GO:0048583 269 0.319
negative regulation of feeding behavior GO:2000252 2 0.261
larval development GO:0002164 2 0.218
embryonic organ morphogenesis GO:0048562 274 0.182
multicellular organism growth GO:0035264 4 0.146
regulation of multicellular organism growth GO:0040014 4 0.128
generation of neurons GO:0048699 385 0.120
embryonic organ development GO:0048568 381 0.119
regulation of stem cell differentiation GO:2000736 4 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.106
cartilage development GO:0051216 96 0.102
cell projection organization GO:0030030 284 0.098
digestive tract morphogenesis GO:0048546 231 0.092
extrinsic apoptotic signaling pathway GO:0097191 3 0.091
aromatic compound biosynthetic process GO:0019438 217 0.086
positive regulation of biological process GO:0048518 253 0.085
vasculature development GO:0001944 278 0.080
locomotion GO:0040011 313 0.080
muscle structure development GO:0061061 196 0.080
heart development GO:0007507 313 0.078
tube morphogenesis GO:0035239 349 0.077
positive regulation of cellular process GO:0048522 201 0.074
positive regulation of cell cycle GO:0045787 3 0.071
striated muscle tissue development GO:0014706 110 0.071
signal transduction GO:0007165 455 0.069
regulation of developmental process GO:0050793 247 0.069
regulation of macromolecule metabolic process GO:0060255 317 0.068
connective tissue development GO:0061448 99 0.067
response to stress GO:0006950 263 0.067
embryonic heart tube development GO:0035050 133 0.065
morphogenesis of an epithelium GO:0002009 333 0.065
cellular component movement GO:0006928 335 0.063
regulation of protein transport GO:0051223 3 0.060
skeletal system development GO:0001501 181 0.059
phagocytosis GO:0006909 3 0.058
cellular nitrogen compound biosynthetic process GO:0044271 218 0.058
response to organic substance GO:0010033 153 0.058
determination of left right symmetry GO:0007368 179 0.056
central nervous system neuron differentiation GO:0021953 74 0.056
convergent extension GO:0060026 118 0.055
myotube differentiation GO:0014902 45 0.054
nuclear transport GO:0051169 4 0.054
cellular macromolecule metabolic process GO:0044260 391 0.054
protein localization to nucleus GO:0034504 3 0.052
regulation of endopeptidase activity GO:0052548 23 0.051
cellular response to hormone stimulus GO:0032870 39 0.049
energy reserve metabolic process GO:0006112 2 0.049
smooth muscle contraction GO:0006939 2 0.049
programmed cell death GO:0012501 119 0.048
determination of bilateral symmetry GO:0009855 204 0.048
tissue remodeling GO:0048771 4 0.048
regulation of establishment of protein localization GO:0070201 4 0.047
enzyme linked receptor protein signaling pathway GO:0007167 106 0.047
skeletal system morphogenesis GO:0048705 102 0.046
chordate embryonic development GO:0043009 271 0.046
secondary metabolic process GO:0019748 3 0.046
neuromuscular synaptic transmission GO:0007274 2 0.046
response to wounding GO:0009611 116 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.043
epithelial tube morphogenesis GO:0060562 148 0.043
gland development GO:0048732 143 0.043
kidney development GO:0001822 92 0.042
multi organism process GO:0051704 134 0.042
regulation of reproductive process GO:2000241 4 0.042
apoptotic process GO:0006915 116 0.041
regulation of primary metabolic process GO:0080090 311 0.040
phagocytosis engulfment GO:0006911 1 0.040
nucleocytoplasmic transport GO:0006913 4 0.040
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.040
nucleotide biosynthetic process GO:0009165 21 0.040
specification of symmetry GO:0009799 204 0.040
carbohydrate homeostasis GO:0033500 1 0.039
embryonic skeletal system development GO:0048706 97 0.039
regulation of apoptotic process GO:0042981 98 0.039
phosphate containing compound metabolic process GO:0006796 108 0.038
camera type eye development GO:0043010 222 0.038
endocrine system development GO:0035270 65 0.038
cell growth GO:0016049 57 0.038
regulation of signaling GO:0023051 235 0.037
hormone secretion GO:0046879 2 0.037
death GO:0016265 121 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.036
cell surface receptor signaling pathway GO:0007166 325 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
digestive system development GO:0055123 289 0.036
negative regulation of ras protein signal transduction GO:0046580 1 0.035
glucose import GO:0046323 2 0.034
response to external stimulus GO:0009605 264 0.034
striated muscle cell development GO:0055002 108 0.034
regulation of dna replication GO:0006275 3 0.034
immune system process GO:0002376 241 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.032
regulation of protein import into nucleus GO:0042306 2 0.032
retina development in camera type eye GO:0060041 146 0.032
embryonic limb morphogenesis GO:0030326 2 0.032
developmental growth GO:0048589 166 0.032
syncytium formation GO:0006949 12 0.031
skeletal muscle tissue development GO:0007519 67 0.031
phosphorus metabolic process GO:0006793 109 0.031
response to chemical GO:0042221 320 0.031
regulation of metabolic process GO:0019222 359 0.030
regulation of cell communication GO:0010646 232 0.030
regulation of protein localization to nucleus GO:1900180 2 0.030
urogenital system development GO:0001655 97 0.030
eye development GO:0001654 277 0.029
renal system development GO:0072001 94 0.029
circadian sleep wake cycle GO:0042745 2 0.029
maintenance of location GO:0051235 4 0.029
digestive tract development GO:0048565 265 0.029
stem cell division GO:0017145 1 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.028
regulation of oocyte development GO:0060281 3 0.028
cellular response to organic substance GO:0071310 105 0.028
protein localization GO:0008104 40 0.028
heart jogging GO:0003146 40 0.028
female sex differentiation GO:0046660 4 0.028
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
negative regulation of protein localization to nucleus GO:1900181 2 0.028
regulation of programmed cell death GO:0043067 101 0.028
nitrogen compound metabolic process GO:0006807 319 0.027
regulation of protein targeting GO:1903533 2 0.027
regulation of jak stat cascade GO:0046425 3 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
anatomical structure homeostasis GO:0060249 36 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.026
regulation of protein complex assembly GO:0043254 3 0.026
positive regulation of epithelial cell differentiation GO:0030858 2 0.026
cell migration GO:0016477 237 0.026
gene expression GO:0010467 252 0.026
autophagy GO:0006914 4 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
response to endogenous stimulus GO:0009719 83 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
viral process GO:0016032 1 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
cellular response to external stimulus GO:0071496 2 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
convergent extension involved in gastrulation GO:0060027 71 0.025
spemann organizer formation at the embryonic shield GO:0060063 2 0.025
sensory organ development GO:0007423 393 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
gastrulation GO:0007369 208 0.025
stem cell proliferation GO:0072089 4 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
response to decreased oxygen levels GO:0036293 25 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
regulation of cell death GO:0010941 103 0.024
multicellular organism reproduction GO:0032504 35 0.024
ear development GO:0043583 127 0.024
small molecule metabolic process GO:0044281 77 0.024
retinal ganglion cell axon guidance GO:0031290 35 0.023
hepaticobiliary system development GO:0061008 98 0.023
adult behavior GO:0030534 2 0.023
mesoderm development GO:0007498 88 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of signal transduction GO:0009966 225 0.023
regulation of peptidase activity GO:0052547 23 0.023
synaptic transmission GO:0007268 35 0.022
aging GO:0007568 2 0.022
striated muscle cell differentiation GO:0051146 129 0.022
muscle cell differentiation GO:0042692 139 0.022
regulation of behavior GO:0050795 24 0.022
cell death GO:0008219 121 0.022
skeletal muscle organ development GO:0060538 78 0.022
neuron projection morphogenesis GO:0048812 161 0.022
localization of cell GO:0051674 244 0.022
protein import into nucleus GO:0006606 3 0.022
regulation of protein catabolic process GO:0042176 1 0.022
immune response GO:0006955 28 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
positive regulation of catabolic process GO:0009896 4 0.022
cellular response to lipid GO:0071396 39 0.022
taxis GO:0042330 109 0.021
regulation of gene expression GO:0010468 265 0.021
response to biotic stimulus GO:0009607 97 0.021
ribose phosphate biosynthetic process GO:0046390 20 0.021
negative regulation of signal transduction GO:0009968 94 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.020
regulation of transcription dna templated GO:0006355 213 0.020
heart looping GO:0001947 94 0.020
translational initiation GO:0006413 3 0.020
developmental programmed cell death GO:0010623 4 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
morphogenesis of embryonic epithelium GO:0016331 30 0.020
regulation of cysteine type endopeptidase activity GO:2000116 21 0.020
determination of heart left right asymmetry GO:0061371 117 0.020
regulation of chondrocyte differentiation GO:0032330 1 0.020
cilium organization GO:0044782 71 0.020
intracellular signal transduction GO:0035556 85 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
response to hormone GO:0009725 48 0.020
pathway restricted smad protein phosphorylation GO:0060389 1 0.020
behavior GO:0007610 74 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
skeletal muscle fiber development GO:0048741 35 0.019
regulation of cytokine production GO:0001817 3 0.019
negative regulation of protein transport GO:0051224 3 0.019
axon guidance GO:0007411 86 0.019
compound eye development GO:0048749 2 0.019
regulation of growth GO:0040008 42 0.019
long chain fatty acid transport GO:0015909 1 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
cellular response to hypoxia GO:0071456 1 0.018
cell part morphogenesis GO:0032990 246 0.018
transport GO:0006810 220 0.018
protein polymerization GO:0051258 4 0.018
organic acid metabolic process GO:0006082 31 0.018
mesodermal cell fate specification GO:0007501 12 0.018
cardiac cell fate commitment GO:0060911 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
definitive hemopoiesis GO:0060216 18 0.018
motor neuron axon guidance GO:0008045 23 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
melanin metabolic process GO:0006582 2 0.018
regulation of lipid catabolic process GO:0050994 2 0.018
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.018
nucleoside phosphate biosynthetic process GO:1901293 21 0.017
embryonic skeletal joint development GO:0072498 3 0.017
positive regulation of programmed cell death GO:0043068 29 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
regeneration GO:0031099 91 0.017
amine metabolic process GO:0009308 2 0.017
single organism metabolic process GO:0044710 217 0.017
chemotaxis GO:0006935 104 0.017
negative regulation of reproductive process GO:2000242 3 0.017
cellular response to estrogen stimulus GO:0071391 24 0.017
somitogenesis GO:0001756 87 0.017
regulation of inflammatory response GO:0050727 2 0.017
oxoacid metabolic process GO:0043436 31 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
cardiogenic plate morphogenesis GO:0003142 1 0.017
response to corticosteroid GO:0031960 1 0.017
oocyte maturation GO:0001556 4 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.016
bmp signaling pathway involved in heart development GO:0061312 15 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
glial cell differentiation GO:0010001 42 0.016
canonical wnt signaling pathway GO:0060070 48 0.016
positive regulation of metabolic process GO:0009893 108 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
negative regulation of cellular process GO:0048523 283 0.016
positive regulation of cell death GO:0010942 29 0.016
collagen fibril organization GO:0030199 1 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
establishment of localization GO:0051234 244 0.016
protein import GO:0017038 3 0.016
neuron projection guidance GO:0097485 86 0.016
positive regulation of cell communication GO:0010647 56 0.016
tetrapyrrole metabolic process GO:0033013 10 0.016
regulation of binding GO:0051098 3 0.016
sequestering of calcium ion GO:0051208 3 0.016
cell cell signaling GO:0007267 52 0.016
single organism nuclear import GO:1902593 3 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
nuclear import GO:0051170 3 0.015
cellular component morphogenesis GO:0032989 336 0.015
single organism localization GO:1902578 225 0.015
cell motility GO:0048870 244 0.015
multi organism cellular process GO:0044764 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular response to nutrient levels GO:0031669 2 0.015
growth GO:0040007 174 0.015
interspecies interaction between organisms GO:0044419 4 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
tissue regeneration GO:0042246 74 0.015
positive regulation of cell differentiation GO:0045597 30 0.015
regulation of hydrolase activity GO:0051336 28 0.015
glucose homeostasis GO:0042593 1 0.015
cognition GO:0050890 1 0.015
cellular amine metabolic process GO:0044106 2 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of locomotion GO:0040012 55 0.014
cellular response to starvation GO:0009267 1 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
single organism cellular localization GO:1902580 46 0.014
blood vessel development GO:0001568 246 0.014
regulation of epithelial to mesenchymal transition GO:0010717 3 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of immune effector process GO:0002699 3 0.014
cellular protein modification process GO:0006464 100 0.014
negative regulation of cytokine production GO:0001818 1 0.014
mesenchyme development GO:0060485 127 0.014
single organism transport GO:0044765 206 0.014
cellular response to stress GO:0033554 62 0.014
apoptotic process involved in morphogenesis GO:0060561 2 0.014
neurotransmitter transport GO:0006836 2 0.014
central nervous system development GO:0007417 387 0.014
carbohydrate derivative biosynthetic process GO:1901137 43 0.014
protein secretion GO:0009306 1 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.014
digestive tract mesoderm development GO:0007502 1 0.014
regulation of biological quality GO:0065008 263 0.014
blood vessel morphogenesis GO:0048514 216 0.014
regulation of histone deacetylation GO:0031063 2 0.014
regulation of protein metabolic process GO:0051246 56 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
response to abiotic stimulus GO:0009628 122 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
axon development GO:0061564 166 0.013
regulation of localization GO:0032879 104 0.013
positive regulation of cell division GO:0051781 2 0.013
wnt signaling pathway GO:0016055 80 0.013
anterior posterior pattern specification GO:0009952 152 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of blood pressure GO:0008217 1 0.013
wound healing GO:0042060 90 0.013
fatty acid transport GO:0015908 1 0.013
defense response GO:0006952 47 0.013
regulation of circadian rhythm GO:0042752 4 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
membrane repolarization GO:0086009 2 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
angiogenesis GO:0001525 158 0.013
reproductive process GO:0022414 40 0.013
regulation of cytokine mediated signaling pathway GO:0001959 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of cellular response to growth factor stimulus GO:0090287 35 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
regulation of circadian sleep wake cycle GO:0042749 1 0.013
myotube cell development GO:0014904 35 0.013
energy homeostasis GO:0097009 3 0.013
lipid storage GO:0019915 1 0.012
regulation of multicellular organismal metabolic process GO:0044246 2 0.012
inner ear development GO:0048839 126 0.012
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.012
negative regulation of biological process GO:0048519 304 0.012
single organism organelle organization GO:1902589 199 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
type b pancreatic cell development GO:0003323 4 0.012
regulation of autophagy GO:0010506 3 0.012
stem cell development GO:0048864 82 0.012
heterocycle metabolic process GO:0046483 290 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
macromolecule localization GO:0033036 54 0.012
metal ion homeostasis GO:0055065 26 0.012
muscle tissue development GO:0060537 110 0.012
antimicrobial humoral response GO:0019730 2 0.012
positive regulation of signal transduction GO:0009967 56 0.012
myeloid cell development GO:0061515 32 0.012
homeostatic process GO:0042592 142 0.012
negative regulation of protein kinase activity GO:0006469 4 0.011
purine ribonucleotide biosynthetic process GO:0009152 20 0.011
regulation of catalytic activity GO:0050790 55 0.011
bmp signaling pathway GO:0030509 52 0.011
optokinetic behavior GO:0007634 9 0.011
peptide transport GO:0015833 1 0.011
inner ear morphogenesis GO:0042472 63 0.011
system process GO:0003008 185 0.011
rna metabolic process GO:0016070 219 0.011
appendage development GO:0048736 80 0.011
regulation of cellular component organization GO:0051128 86 0.011
feeding behavior GO:0007631 5 0.011
photoreceptor cell outer segment organization GO:0035845 9 0.011
protein metabolic process GO:0019538 183 0.011
regulation of bone mineralization GO:0030500 2 0.011
cellular ketone metabolic process GO:0042180 11 0.011
convergent extension involved in organogenesis GO:0060029 10 0.011
negative regulation of cell communication GO:0010648 96 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
negative regulation of defense response GO:0031348 2 0.011
negative regulation of molecular function GO:0044092 23 0.011
regulation of cell differentiation GO:0045595 142 0.011
positive regulation of response to stimulus GO:0048584 80 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
positive regulation of neuron death GO:1901216 1 0.010
ribonucleotide biosynthetic process GO:0009260 20 0.010
cranial nerve development GO:0021545 42 0.010
cellular component assembly GO:0022607 170 0.010
endocardial cushion formation GO:0003272 2 0.010
regulation of organ morphogenesis GO:2000027 35 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
negative regulation of catabolic process GO:0009895 3 0.010
cation transport GO:0006812 81 0.010
cytoskeleton organization GO:0007010 96 0.010
determination of left right asymmetry in nervous system GO:0035545 4 0.010
mesoderm formation GO:0001707 43 0.010
positive regulation of developmental process GO:0051094 50 0.010
phosphorylation GO:0016310 69 0.010
mucopolysaccharide metabolic process GO:1903510 2 0.010
cellular response to interferon gamma GO:0071346 1 0.010
regulation of molecular function GO:0065009 70 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
spinal cord motor neuron differentiation GO:0021522 26 0.010
head development GO:0060322 303 0.010
appendage morphogenesis GO:0035107 56 0.010
fatty acid beta oxidation GO:0006635 1 0.010
neuron projection development GO:0031175 180 0.010
establishment of localization in cell GO:0051649 77 0.010

nfatc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.211
disease of metabolism DOID:0014667 0 0.059
bone development disease DOID:0080006 0 0.040
bone disease DOID:0080001 0 0.040
dysostosis DOID:1934 0 0.040
musculoskeletal system disease DOID:17 0 0.040
connective tissue disease DOID:65 0 0.040
synostosis DOID:11971 0 0.040
cardiovascular system disease DOID:1287 0 0.029
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015