Danio rerio

0 known processes

hyou1

hypoxia up-regulated 1

(Aliases: id:ibd5056,wu:fd14c05,zgc:56019)

hyou1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to topologically incorrect protein GO:0035967 2 0.962
endoplasmic reticulum unfolded protein response GO:0030968 2 0.881
signal transduction GO:0007165 455 0.649
modification dependent protein catabolic process GO:0019941 3 0.614
response to topologically incorrect protein GO:0035966 2 0.590
cellular response to unfolded protein GO:0034620 2 0.515
response to endoplasmic reticulum stress GO:0034976 6 0.508
ubiquitin dependent protein catabolic process GO:0006511 3 0.496
er nucleus signaling pathway GO:0006984 2 0.454
response to unfolded protein GO:0006986 2 0.448
larval development GO:0002164 2 0.425
cellular macromolecule biosynthetic process GO:0034645 224 0.371
response to stress GO:0006950 263 0.340
Mouse Rat
cellular protein catabolic process GO:0044257 4 0.333
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.258
response to organic substance GO:0010033 153 0.245
proteasomal protein catabolic process GO:0010498 2 0.226
cellular response to organic substance GO:0071310 105 0.210
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.197
modification dependent macromolecule catabolic process GO:0043632 3 0.165
cellular protein metabolic process GO:0044267 129 0.165
aging GO:0007568 2 0.148
protein metabolic process GO:0019538 183 0.144
response to chemical GO:0042221 320 0.135
cellular response to chemical stimulus GO:0070887 157 0.134
cellular biosynthetic process GO:0044249 286 0.132
cellular macromolecule metabolic process GO:0044260 391 0.131
regulation of response to stimulus GO:0048583 269 0.124
cell death GO:0008219 121 0.121
cellular component biogenesis GO:0044085 178 0.121
growth GO:0040007 174 0.116
embryo development ending in birth or egg hatching GO:0009792 271 0.108
tube morphogenesis GO:0035239 349 0.103
response to external stimulus GO:0009605 264 0.096
regulation of signaling GO:0023051 235 0.095
embryonic organ development GO:0048568 381 0.091
cell substrate junction assembly GO:0007044 2 0.088
regulation of cell death GO:0010941 103 0.088
multicellular organism growth GO:0035264 4 0.085
regulation of biological quality GO:0065008 263 0.077
positive regulation of secretion by cell GO:1903532 1 0.075
biosynthetic process GO:0009058 294 0.074
regulation of cell communication GO:0010646 232 0.072
purine nucleoside monophosphate catabolic process GO:0009128 4 0.071
maintenance of location GO:0051235 4 0.069
regulation of multicellular organism growth GO:0040014 4 0.068
lipid storage GO:0019915 1 0.067
programmed cell death GO:0012501 119 0.063
organonitrogen compound metabolic process GO:1901564 74 0.062
response to heat GO:0009408 6 0.059
protein n linked glycosylation GO:0006487 1 0.058
brain development GO:0007420 293 0.058
regulation of multicellular organismal process GO:0051239 277 0.054
cellular component assembly GO:0022607 170 0.053
regulation of signal transduction GO:0009966 225 0.053
cellular response to stress GO:0033554 62 0.052
ion transport GO:0006811 114 0.051
response to biotic stimulus GO:0009607 97 0.049
regulation of nucleoside metabolic process GO:0009118 2 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
organic substance biosynthetic process GO:1901576 289 0.047
death GO:0016265 121 0.046
regulation of cytokine production GO:0001817 3 0.046
head development GO:0060322 303 0.045
positive regulation of nuclease activity GO:0032075 1 0.045
transmembrane transport GO:0055085 120 0.045
determination of left right symmetry GO:0007368 179 0.045
fin development GO:0033333 77 0.043
cellular response to nutrient levels GO:0031669 2 0.043
specification of symmetry GO:0009799 204 0.042
positive regulation of metabolic process GO:0009893 108 0.041
cell motility GO:0048870 244 0.041
regulation of metabolic process GO:0019222 359 0.040
negative regulation of cell communication GO:0010648 96 0.040
glycoprotein metabolic process GO:0009100 23 0.040
digestive system development GO:0055123 289 0.039
system process GO:0003008 185 0.038
positive regulation of cell activation GO:0050867 1 0.038
pectoral fin development GO:0033339 50 0.038
regulation of biosynthetic process GO:0009889 250 0.037
sensory organ development GO:0007423 393 0.035
regulation of neurotransmitter secretion GO:0046928 1 0.034
response to external biotic stimulus GO:0043207 97 0.034
cellular response to extracellular stimulus GO:0031668 2 0.033
response to virus GO:0009615 21 0.033
regulation of blood vessel size GO:0050880 2 0.032
amine metabolic process GO:0009308 2 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
positive regulation of immune effector process GO:0002699 3 0.032
central nervous system development GO:0007417 387 0.032
organophosphate biosynthetic process GO:0090407 23 0.032
regulation of nuclease activity GO:0032069 1 0.032
heart development GO:0007507 313 0.031
positive regulation of multicellular organismal process GO:0051240 52 0.031
response to temperature stimulus GO:0009266 15 0.031
cation transmembrane transport GO:0098655 65 0.031
regulation of protein ubiquitination GO:0031396 3 0.030
gtp metabolic process GO:0046039 4 0.030
regulation of nucleotide catabolic process GO:0030811 2 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
intracellular signal transduction GO:0035556 85 0.029
negative regulation of cell death GO:0060548 60 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
negative regulation of cellular catabolic process GO:0031330 3 0.029
cation transport GO:0006812 81 0.029
cell surface receptor signaling pathway GO:0007166 325 0.028
regulation of gene expression GO:0010468 265 0.028
regulation of muscle contraction GO:0006937 3 0.028
response to oxygen containing compound GO:1901700 55 0.028
regulation of programmed cell death GO:0043067 101 0.028
inorganic ion transmembrane transport GO:0098660 57 0.027
protein modification process GO:0036211 100 0.027
carbohydrate derivative biosynthetic process GO:1901137 43 0.027
exocytosis GO:0006887 1 0.027
negative regulation of signaling GO:0023057 96 0.027
single organism metabolic process GO:0044710 217 0.027
homeostatic process GO:0042592 142 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.026
regulation of production of molecular mediator of immune response GO:0002700 1 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
regulation of metal ion transport GO:0010959 4 0.026
regulation of developmental process GO:0050793 247 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
protein import GO:0017038 3 0.025
positive regulation of secretion GO:0051047 1 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
positive regulation of cytokine production GO:0001819 2 0.025
cell migration GO:0016477 237 0.024
developmental pigmentation GO:0048066 48 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
heart process GO:0003015 71 0.024
regulation of molecular function GO:0065009 70 0.024
cell projection morphogenesis GO:0048858 244 0.024
organic substance catabolic process GO:1901575 28 0.024
peptide metabolic process GO:0006518 1 0.024
positive regulation of biological process GO:0048518 253 0.024
regulation of cardiac muscle contraction GO:0055117 2 0.024
determination of bilateral symmetry GO:0009855 204 0.024
circulatory system process GO:0003013 87 0.024
collagen metabolic process GO:0032963 2 0.023
cellular amine metabolic process GO:0044106 2 0.023
chordate embryonic development GO:0043009 271 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
regulation of autophagy GO:0010506 3 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
apoptotic process GO:0006915 116 0.022
regulation of apoptotic process GO:0042981 98 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of tube size GO:0035150 2 0.021
rna biosynthetic process GO:0032774 181 0.021
water homeostasis GO:0030104 4 0.021
atp catabolic process GO:0006200 4 0.020
immune system development GO:0002520 191 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
negative regulation of cellular process GO:0048523 283 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
epithelial tube morphogenesis GO:0060562 148 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
single organism localization GO:1902578 225 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
regulation of growth GO:0040008 42 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
mesenchyme development GO:0060485 127 0.019
transport GO:0006810 220 0.019
proteolysis GO:0006508 38 0.018
cellular response to starvation GO:0009267 1 0.018
cellular catabolic process GO:0044248 27 0.018
ovulation cycle process GO:0022602 2 0.018
negative regulation of biological process GO:0048519 304 0.018
endodermal digestive tract morphogenesis GO:0061031 2 0.018
otolith development GO:0048840 32 0.018
macromolecule biosynthetic process GO:0009059 227 0.017
locomotion GO:0040011 313 0.017
erythrocyte development GO:0048821 24 0.017
response to wounding GO:0009611 116 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
regulation of gtpase activity GO:0043087 2 0.017
response to ethanol GO:0045471 6 0.017
response to other organism GO:0051707 97 0.017
positive regulation of cell cycle GO:0045787 3 0.017
regulation of developmental growth GO:0048638 38 0.016
embryonic heart tube development GO:0035050 133 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
immunoglobulin mediated immune response GO:0016064 3 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
response to alcohol GO:0097305 14 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
nuclear export GO:0051168 1 0.016
calcium mediated signaling GO:0019722 2 0.016
positive regulation of immune system process GO:0002684 17 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
positive regulation of cellular process GO:0048522 201 0.016
regulation of localization GO:0032879 104 0.016
regulation of cell activation GO:0050865 1 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
positive regulation of transport GO:0051050 2 0.016
phosphate containing compound metabolic process GO:0006796 108 0.015
heart contraction GO:0060047 71 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
blood circulation GO:0008015 87 0.015
autophagy GO:0006914 4 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
intrinsic apoptotic signaling pathway GO:0097193 20 0.015
type i interferon production GO:0032606 2 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
carbohydrate homeostasis GO:0033500 1 0.015
midbrain development GO:0030901 28 0.015
cell morphogenesis GO:0000902 289 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
mesoderm development GO:0007498 88 0.015
regulation of binding GO:0051098 3 0.015
negative regulation of signal transduction GO:0009968 94 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
lateral line system development GO:0048925 76 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
meiotic nuclear division GO:0007126 4 0.014
catabolic process GO:0009056 32 0.014
response to drug GO:0042493 3 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
cellular macromolecule catabolic process GO:0044265 12 0.014
macromolecule modification GO:0043412 111 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
neurotransmitter secretion GO:0007269 2 0.014
positive regulation of translation GO:0045727 1 0.014
response to abiotic stimulus GO:0009628 122 0.014
Rat
developmental growth GO:0048589 166 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.014
organism emergence from protective structure GO:0071684 4 0.013
digestive tract morphogenesis GO:0048546 231 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
single organism organelle organization GO:1902589 199 0.013
posterior lateral line neuromast development GO:0048919 20 0.013
positive regulation of catabolic process GO:0009896 4 0.013
cellular protein modification process GO:0006464 100 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
hormone transport GO:0009914 2 0.013
b cell activation GO:0042113 2 0.013
nucleotide metabolic process GO:0009117 28 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
hormone secretion GO:0046879 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
ear development GO:0043583 127 0.012
oxoacid metabolic process GO:0043436 31 0.012
single organism biosynthetic process GO:0044711 71 0.012
toxin transport GO:1901998 2 0.012
negative regulation of blood circulation GO:1903523 2 0.012
calcium ion import GO:0070509 4 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
small molecule metabolic process GO:0044281 77 0.012
positive regulation of multi organism process GO:0043902 3 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
cellular localization GO:0051641 97 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
heterocycle metabolic process GO:0046483 290 0.012
regulation of purine nucleotide metabolic process GO:1900542 17 0.012
response to endogenous stimulus GO:0009719 83 0.012
generation of neurons GO:0048699 385 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
peptide transport GO:0015833 1 0.012
purine ribonucleotide biosynthetic process GO:0009152 20 0.012
establishment of localization GO:0051234 244 0.012
dna catabolic process GO:0006308 1 0.012
neuron development GO:0048666 262 0.012
defense response to fungus GO:0050832 2 0.012
multi organism process GO:0051704 134 0.012
macromolecule catabolic process GO:0009057 15 0.011
regulation of apoptotic signaling pathway GO:2001233 12 0.011
pigmentation GO:0043473 85 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
hemopoiesis GO:0030097 183 0.011
protein targeting to membrane GO:0006612 1 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
gene expression GO:0010467 252 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
regulation of inflammatory response GO:0050727 2 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
negative regulation of catabolic process GO:0009895 3 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of protein binding GO:0043393 3 0.011
b cell mediated immunity GO:0019724 3 0.011
response to hypoxia GO:0001666 25 0.011
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
olfactory lobe development GO:0021988 4 0.011
stem cell maintenance GO:0019827 4 0.011
erythrocyte differentiation GO:0030218 54 0.011
negative regulation of autophagy GO:0010507 1 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
nitric oxide metabolic process GO:0046209 2 0.011
positive regulation of camp metabolic process GO:0030816 2 0.011
positive regulation of transcription dna templated GO:0045893 57 0.010
ovulation cycle GO:0042698 2 0.010
iron ion transmembrane transport GO:0034755 3 0.010
skeletal system development GO:0001501 181 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
recombinational repair GO:0000725 1 0.010
female gonad development GO:0008585 4 0.010
ion transmembrane transport GO:0034220 91 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
response to bacterium GO:0009617 58 0.010
nucleoside phosphate metabolic process GO:0006753 28 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
mononuclear cell proliferation GO:0032943 1 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
nuclear import GO:0051170 3 0.010
regulation of cell motility GO:2000145 46 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.010
cranial ganglion development GO:0061550 3 0.010
regulation of protein catabolic process GO:0042176 1 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010

hyou1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.133
nervous system disease DOID:863 0 0.026
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
auditory system disease DOID:2742 0 0.016
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.016
nonsyndromic deafness DOID:0050563 0 0.016
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014
connective tissue disease DOID:65 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011