Danio rerio

0 known processes

dhh

desert hedgehog

dhh biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.049
maintenance of location GO:0051235 4 0.044
cognition GO:0050890 1 0.038
regulation of macromolecule metabolic process GO:0060255 317 0.036
signal transduction GO:0007165 455 0.035
aging GO:0007568 2 0.035
stem cell maintenance GO:0019827 4 0.032
multicellular organism growth GO:0035264 4 0.032
response to chemical GO:0042221 320 0.031
Rat
regulation of cytokine production GO:0001817 3 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
embryonic organ development GO:0048568 381 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
regulation of biological quality GO:0065008 263 0.029
Rat
cell surface receptor signaling pathway GO:0007166 325 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
gene expression GO:0010467 252 0.027
cellular response to external stimulus GO:0071496 2 0.027
nuclear transport GO:0051169 4 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
regulation of protein complex assembly GO:0043254 3 0.026
regulation of metabolic process GO:0019222 359 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
nitrogen compound metabolic process GO:0006807 319 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
positive regulation of catabolic process GO:0009896 4 0.025
phagocytosis GO:0006909 3 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
cellular response to nutrient levels GO:0031669 2 0.025
lipid storage GO:0019915 1 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
negative regulation of biological process GO:0048519 304 0.025
regulation of response to stimulus GO:0048583 269 0.024
response to drug GO:0042493 3 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
response to external stimulus GO:0009605 264 0.024
nucleic acid metabolic process GO:0090304 244 0.024
heterocycle metabolic process GO:0046483 290 0.024
sensory organ development GO:0007423 393 0.024
positive regulation of transport GO:0051050 2 0.024
system process GO:0003008 185 0.023
Rat
rna metabolic process GO:0016070 219 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
adult behavior GO:0030534 2 0.023
cellular component movement GO:0006928 335 0.023
positive regulation of cell cycle GO:0045787 3 0.023
gland development GO:0048732 143 0.023
immune system process GO:0002376 241 0.023
single organism metabolic process GO:0044710 217 0.022
neuron differentiation GO:0030182 353 0.022
cell projection morphogenesis GO:0048858 244 0.022
cell morphogenesis GO:0000902 289 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
organic substance biosynthetic process GO:1901576 289 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of signal transduction GO:0009966 225 0.022
regulation of mrna processing GO:0050684 3 0.022
response to carbohydrate GO:0009743 3 0.022
autophagy GO:0006914 4 0.022
mitochondrion organization GO:0007005 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of cell activation GO:0050865 1 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
eye development GO:0001654 277 0.021
heart development GO:0007507 313 0.021
leukocyte proliferation GO:0070661 1 0.021
regulation of blood pressure GO:0008217 1 0.021
central nervous system development GO:0007417 387 0.021
regulation of protein transport GO:0051223 3 0.021
amine metabolic process GO:0009308 2 0.021
regulation of blood vessel size GO:0050880 2 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
regulation of protein catabolic process GO:0042176 1 0.021
stem cell proliferation GO:0072089 4 0.020
tissue remodeling GO:0048771 4 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
cell projection organization GO:0030030 284 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
regulation of reproductive process GO:2000241 4 0.020
head development GO:0060322 303 0.020
immune system development GO:0002520 191 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
regulation of primary metabolic process GO:0080090 311 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
establishment of localization GO:0051234 244 0.019
digestive system development GO:0055123 289 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of signaling GO:0023051 235 0.019
vasculature development GO:0001944 278 0.019
regulation of tube size GO:0035150 2 0.019
regulation of metal ion transport GO:0010959 4 0.019
regulation of synapse assembly GO:0051963 3 0.019
cellular component disassembly GO:0022411 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
chordate embryonic development GO:0043009 271 0.019
cell part morphogenesis GO:0032990 246 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
protein import into nucleus GO:0006606 3 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of cellular metabolic process GO:0031323 320 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of gene expression GO:0010468 265 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
protein import GO:0017038 3 0.018
response to hexose GO:0009746 3 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
generation of neurons GO:0048699 385 0.018
negative regulation of catabolic process GO:0009895 3 0.018
protein heterooligomerization GO:0051291 1 0.018
cellular biosynthetic process GO:0044249 286 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of developmental process GO:0050793 247 0.018
positive regulation of cytokine production GO:0001819 2 0.018
regulation of biosynthetic process GO:0009889 250 0.018
exocytosis GO:0006887 1 0.018
protein metabolic process GO:0019538 183 0.018
biosynthetic process GO:0009058 294 0.018
protein localization to nucleus GO:0034504 3 0.018
cellular ketone metabolic process GO:0042180 11 0.018
protein acetylation GO:0006473 2 0.018
cellular protein catabolic process GO:0044257 4 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
response to glucocorticoid GO:0051384 1 0.017
peptide metabolic process GO:0006518 1 0.017
organic acid metabolic process GO:0006082 31 0.017
specification of symmetry GO:0009799 204 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
membrane fusion GO:0061025 2 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
mononuclear cell proliferation GO:0032943 1 0.017
response to monosaccharide GO:0034284 3 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
response to stress GO:0006950 263 0.017
single organism nuclear import GO:1902593 3 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
b cell activation GO:0042113 2 0.016
cell migration GO:0016477 237 0.016
cellular response to starvation GO:0009267 1 0.016
positive regulation of cell activation GO:0050867 1 0.016
localization of cell GO:0051674 244 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
response to corticosteroid GO:0031960 1 0.016
regulation of inflammatory response GO:0050727 2 0.016
protein dephosphorylation GO:0006470 3 0.016
organelle fusion GO:0048284 3 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
positive regulation of secretion GO:0051047 1 0.016
female sex differentiation GO:0046660 4 0.016
hemopoiesis GO:0030097 183 0.016
lipid catabolic process GO:0016042 4 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
nuclear import GO:0051170 3 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
homeostatic process GO:0042592 142 0.015
cytokinesis GO:0000910 3 0.015
transcription dna templated GO:0006351 181 0.015
protein acylation GO:0043543 3 0.015
regulation of cell communication GO:0010646 232 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
locomotion GO:0040011 313 0.015
regulation of binding GO:0051098 3 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
response to organic substance GO:0010033 153 0.015
Rat
modification dependent protein catabolic process GO:0019941 3 0.015
sensory organ morphogenesis GO:0090596 200 0.015
blood vessel development GO:0001568 246 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
inner ear development GO:0048839 126 0.015
digestive tract development GO:0048565 265 0.015
chemosensory behavior GO:0007635 1 0.015
female gonad development GO:0008585 4 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of dendrite development GO:0050773 3 0.015
nucleic acid templated transcription GO:0097659 181 0.015
macroautophagy GO:0016236 1 0.015
developmental growth GO:0048589 166 0.015
regulation of protein targeting GO:1903533 2 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
positive regulation of immune effector process GO:0002699 3 0.015
phagocytosis engulfment GO:0006911 1 0.015
regulation of cell shape GO:0008360 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
secondary metabolic process GO:0019748 3 0.015
cell motility GO:0048870 244 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
peptide transport GO:0015833 1 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
retina development in camera type eye GO:0060041 146 0.014
negative regulation of cellular process GO:0048523 283 0.014
hormone secretion GO:0046879 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
camera type eye development GO:0043010 222 0.014
cellular amide metabolic process GO:0043603 4 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
cell death GO:0008219 121 0.014
protein secretion GO:0009306 1 0.014
meiotic cell cycle process GO:1903046 3 0.014
brain development GO:0007420 293 0.014
stem cell division GO:0017145 1 0.014
regionalization GO:0003002 274 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
response to alkaloid GO:0043279 2 0.014
single organism membrane fusion GO:0044801 2 0.014
response to nutrient GO:0007584 3 0.014
rna biosynthetic process GO:0032774 181 0.014
negative regulation of protein transport GO:0051224 3 0.014
carbohydrate homeostasis GO:0033500 1 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
blood vessel morphogenesis GO:0048514 216 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
cellular response to oxygen levels GO:0071453 1 0.014
cell substrate adhesion GO:0031589 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
oxoacid metabolic process GO:0043436 31 0.014
lymphocyte proliferation GO:0046651 1 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of cell projection assembly GO:0060491 4 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
hormone transport GO:0009914 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.014
regulation of circadian rhythm GO:0042752 4 0.014
regulation of organ growth GO:0046620 3 0.014
response to glucose GO:0009749 3 0.014
endocrine process GO:0050886 2 0.013
response to uv GO:0009411 3 0.013
neuroblast proliferation GO:0007405 2 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
determination of bilateral symmetry GO:0009855 204 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
single organism localization GO:1902578 225 0.013
somatic muscle development GO:0007525 4 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
cellular response to radiation GO:0071478 4 0.013
organelle organization GO:0006996 227 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
protein polymerization GO:0051258 4 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
neurotransmitter transport GO:0006836 2 0.013
compound eye development GO:0048749 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
multicellular organismal response to stress GO:0033555 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
cellular component assembly GO:0022607 170 0.013
digestive tract morphogenesis GO:0048546 231 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
membrane invagination GO:0010324 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
mesenchyme development GO:0060485 127 0.013
growth GO:0040007 174 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
glucose homeostasis GO:0042593 1 0.013
single organism transport GO:0044765 206 0.013
regulation of gtpase activity GO:0043087 2 0.013
death GO:0016265 121 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
developmental programmed cell death GO:0010623 4 0.013
small molecule metabolic process GO:0044281 77 0.013
synaptic vesicle localization GO:0097479 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
regulation of autophagy GO:0010506 3 0.012
post embryonic organ development GO:0048569 4 0.012
ear development GO:0043583 127 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
negative regulation of kinase activity GO:0033673 4 0.012
multi organism process GO:0051704 134 0.012
protein complex disassembly GO:0043241 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
glial cell migration GO:0008347 3 0.012
angiogenesis GO:0001525 158 0.012
sleep GO:0030431 1 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
determination of left right symmetry GO:0007368 179 0.012
axonogenesis GO:0007409 152 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
meiotic nuclear division GO:0007126 4 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
response to biotic stimulus GO:0009607 97 0.012
transport GO:0006810 220 0.012
response to external biotic stimulus GO:0043207 97 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
single fertilization GO:0007338 3 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
regulation of transporter activity GO:0032409 2 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
neuron development GO:0048666 262 0.012
multi organism cellular process GO:0044764 2 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of dna replication GO:0006275 3 0.012
atp catabolic process GO:0006200 4 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
cellular response to hypoxia GO:0071456 1 0.012
smooth muscle contraction GO:0006939 2 0.011
lipid homeostasis GO:0055088 3 0.011
viral process GO:0016032 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
response to vitamin GO:0033273 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of cellular process GO:0048522 201 0.011
apoptotic process GO:0006915 116 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
muscle structure development GO:0061061 196 0.011
regulation of rna metabolic process GO:0051252 224 0.011
epidermal cell fate specification GO:0009957 4 0.011
intracellular signal transduction GO:0035556 85 0.011
negative regulation of secretion GO:0051048 2 0.011
regulation of cell death GO:0010941 103 0.011
liver development GO:0001889 96 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
single organism organelle organization GO:1902589 199 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
germ line stem cell maintenance GO:0030718 2 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
adherens junction organization GO:0034332 4 0.011
blood circulation GO:0008015 87 0.011
cellular protein metabolic process GO:0044267 129 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
positive regulation of cell killing GO:0031343 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
cellular component biogenesis GO:0044085 178 0.011
neuron projection morphogenesis GO:0048812 161 0.011
neurotransmitter secretion GO:0007269 2 0.011
golgi vesicle transport GO:0048193 3 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
double strand break repair GO:0006302 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
trabecula morphogenesis GO:0061383 2 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
sequestering of metal ion GO:0051238 3 0.011
anterior posterior pattern specification GO:0009952 152 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
regulation of endocrine process GO:0044060 2 0.011
small molecule catabolic process GO:0044282 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
rna localization GO:0006403 4 0.011
protein homooligomerization GO:0051260 3 0.011
negative regulation of secretion by cell GO:1903531 2 0.010
negative regulation of metabolic process GO:0009892 86 0.010
rna 3 end processing GO:0031123 2 0.010
regulation of localization GO:0032879 104 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of apoptotic process GO:0042981 98 0.010
negative regulation of cytokine production GO:0001818 1 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
regulation of growth rate GO:0040009 1 0.010
mesoderm development GO:0007498 88 0.010
hepaticobiliary system development GO:0061008 98 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
programmed cell death GO:0012501 119 0.010
sensory perception of pain GO:0019233 1 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
regulation of jak stat cascade GO:0046425 3 0.010
actin filament polymerization GO:0030041 2 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010

dhh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.010