Danio rerio

32 known processes

mapkapk2a

mitogen-activated protein kinase-activated protein kinase 2a

(Aliases: wu:fc56c10,wu:fb30e10,wu:fi03a01,mapkapk2)

mapkapk2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.497
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.353
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.304
Fly
modification dependent protein catabolic process GO:0019941 3 0.252
signal transduction GO:0007165 455 0.203
Human Mouse Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.197
organelle organization GO:0006996 227 0.194
cellular macromolecule metabolic process GO:0044260 391 0.189
Human Mouse
tube morphogenesis GO:0035239 349 0.188
ubiquitin dependent protein catabolic process GO:0006511 3 0.172
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.170
modification dependent macromolecule catabolic process GO:0043632 3 0.162
negative regulation of cellular process GO:0048523 283 0.161
establishment of localization GO:0051234 244 0.158
Mouse
regulation of metabolic process GO:0019222 359 0.155
Human Mouse Fly
regulation of cell death GO:0010941 103 0.150
cellular aromatic compound metabolic process GO:0006725 295 0.149
nucleobase containing compound metabolic process GO:0006139 274 0.143
negative regulation of biological process GO:0048519 304 0.142
digestive system development GO:0055123 289 0.133
response to topologically incorrect protein GO:0035966 2 0.124
cellular nitrogen compound metabolic process GO:0034641 290 0.123
larval development GO:0002164 2 0.119
positive regulation of transport GO:0051050 2 0.115
rna metabolic process GO:0016070 219 0.104
gastrulation with mouth forming second GO:0001702 44 0.098
negative regulation of cell communication GO:0010648 96 0.097
regulation of translational initiation GO:0006446 1 0.097
nuclear transport GO:0051169 4 0.096
proteasomal protein catabolic process GO:0010498 2 0.094
regulation of biosynthetic process GO:0009889 250 0.093
apoptotic process GO:0006915 116 0.091
response to organic substance GO:0010033 153 0.091
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.089
odontogenesis of dentin containing tooth GO:0042475 1 0.089
cellular response to organic substance GO:0071310 105 0.089
Human
regulation of signal transduction GO:0009966 225 0.089
Fly
digestive tract development GO:0048565 265 0.089
cell surface receptor signaling pathway GO:0007166 325 0.087
Human
cellular protein catabolic process GO:0044257 4 0.087
stem cell proliferation GO:0072089 4 0.087
organic substance biosynthetic process GO:1901576 289 0.086
organic cyclic compound metabolic process GO:1901360 301 0.084
regulation of cell communication GO:0010646 232 0.084
Fly
protein metabolic process GO:0019538 183 0.083
Human Mouse
cellular response to chemical stimulus GO:0070887 157 0.083
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.081
response to chemical GO:0042221 320 0.080
Human Mouse
locomotion GO:0040011 313 0.079
negative regulation of signal transduction GO:0009968 94 0.079
nucleic acid metabolic process GO:0090304 244 0.078
guanosine containing compound metabolic process GO:1901068 4 0.077
cellular protein metabolic process GO:0044267 129 0.076
Human Mouse
gene expression GO:0010467 252 0.075
Human Mouse
central nervous system development GO:0007417 387 0.073
single organism localization GO:1902578 225 0.071
stem cell division GO:0017145 1 0.071
response to other organism GO:0051707 97 0.069
Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.069
morphogenesis of an epithelial sheet GO:0002011 49 0.068
autophagy GO:0006914 4 0.066
hematopoietic or lymphoid organ development GO:0048534 191 0.066
meiotic nuclear division GO:0007126 4 0.066
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.065
organelle fusion GO:0048284 3 0.065
nitrogen compound metabolic process GO:0006807 319 0.065
cellular biosynthetic process GO:0044249 286 0.064
single fertilization GO:0007338 3 0.064
single organism organelle organization GO:1902589 199 0.064
regulation of primary metabolic process GO:0080090 311 0.063
oocyte construction GO:0007308 5 0.063
er nucleus signaling pathway GO:0006984 2 0.063
regulation of apoptotic process GO:0042981 98 0.063
morphogenesis of an epithelium GO:0002009 333 0.062
embryo development ending in birth or egg hatching GO:0009792 271 0.062
embryonic organ development GO:0048568 381 0.061
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.060
cellular component disassembly GO:0022411 1 0.060
negative regulation of protein phosphorylation GO:0001933 4 0.059
death GO:0016265 121 0.059
nucleocytoplasmic transport GO:0006913 4 0.058
establishment of localization in cell GO:0051649 77 0.057
regulation of mrna processing GO:0050684 3 0.057
cell death GO:0008219 121 0.056
regulation of cellular protein metabolic process GO:0032268 52 0.056
negative regulation of signaling GO:0023057 96 0.055
regulation of cellular biosynthetic process GO:0031326 245 0.055
regulation of response to stimulus GO:0048583 269 0.055
Mouse Fly
positive regulation of map kinase activity GO:0043406 3 0.054
response to abiotic stimulus GO:0009628 122 0.054
Fly
single organism transport GO:0044765 206 0.054
phosphate containing compound metabolic process GO:0006796 108 0.053
regulation of macromolecule biosynthetic process GO:0010556 225 0.052
gtp metabolic process GO:0046039 4 0.051
cellular response to unfolded protein GO:0034620 2 0.051
endoplasmic reticulum unfolded protein response GO:0030968 2 0.051
cell migration GO:0016477 237 0.051
immune system development GO:0002520 191 0.051
macromolecule biosynthetic process GO:0009059 227 0.050
segmentation GO:0035282 97 0.050
spindle assembly GO:0051225 2 0.050
biosynthetic process GO:0009058 294 0.049
programmed cell death GO:0012501 119 0.049
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.048
response to external biotic stimulus GO:0043207 97 0.048
Mouse
response to drug GO:0042493 3 0.048
hemopoiesis GO:0030097 183 0.048
transport GO:0006810 220 0.048
Mouse
gtp catabolic process GO:0006184 2 0.048
translational initiation GO:0006413 3 0.048
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.047
response to unfolded protein GO:0006986 2 0.047
positive regulation of secretion GO:0051047 1 0.047
positive regulation of secretion by cell GO:1903532 1 0.047
epiboly GO:0090504 41 0.047
regulation of developmental process GO:0050793 247 0.047
Fly
positive regulation of catabolic process GO:0009896 4 0.047
heterocycle metabolic process GO:0046483 290 0.046
protein dephosphorylation GO:0006470 3 0.046
cellular response to topologically incorrect protein GO:0035967 2 0.046
g1 s transition of mitotic cell cycle GO:0000082 1 0.045
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.045
protein targeting to nucleus GO:0044744 3 0.044
regulation of hormone secretion GO:0046883 2 0.043
translation GO:0006412 5 0.043
regulation of localization GO:0032879 104 0.043
growth GO:0040007 174 0.043
axis specification GO:0009798 43 0.043
gastrulation GO:0007369 208 0.042
regulation of cell activation GO:0050865 1 0.042
head development GO:0060322 303 0.042
brain development GO:0007420 293 0.042
negative regulation of protein kinase activity GO:0006469 4 0.042
eye development GO:0001654 277 0.042
transcription dna templated GO:0006351 181 0.042
regulation of mrna splicing via spliceosome GO:0048024 3 0.041
protein import into nucleus GO:0006606 3 0.041
response to biotic stimulus GO:0009607 97 0.041
Mouse
peptidyl serine modification GO:0018209 2 0.041
Human
chordate embryonic development GO:0043009 271 0.041
cell cycle g1 s phase transition GO:0044843 1 0.041
meiotic cell cycle process GO:1903046 3 0.041
multicellular organism growth GO:0035264 4 0.040
small molecule metabolic process GO:0044281 77 0.040
peptide transport GO:0015833 1 0.040
regulation of nucleotide catabolic process GO:0030811 2 0.040
cellular protein modification process GO:0006464 100 0.040
Human Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.039
regulation of cellular ketone metabolic process GO:0010565 7 0.039
intracellular signal transduction GO:0035556 85 0.039
Fly
single organism metabolic process GO:0044710 217 0.039
Fly
striated muscle cell differentiation GO:0051146 129 0.039
mitochondrion organization GO:0007005 4 0.038
regulation of establishment of protein localization GO:0070201 4 0.038
regionalization GO:0003002 274 0.038
anterior posterior pattern specification GO:0009952 152 0.038
rna biosynthetic process GO:0032774 181 0.038
protein modification process GO:0036211 100 0.038
Human Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.037
regulation of stem cell proliferation GO:0072091 2 0.037
protein import GO:0017038 3 0.037
regulation of protein ubiquitination GO:0031396 3 0.037
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.037
glial cell proliferation GO:0014009 4 0.037
protein polyubiquitination GO:0000209 4 0.037
positive regulation of cellular catabolic process GO:0031331 3 0.037
single organism membrane fusion GO:0044801 2 0.037
heterocycle biosynthetic process GO:0018130 215 0.036
mrna metabolic process GO:0016071 20 0.036
cellular component assembly GO:0022607 170 0.036
negative regulation of reproductive process GO:2000242 3 0.036
hormone transport GO:0009914 2 0.036
stem cell fate commitment GO:0048865 1 0.036
regulation of stem cell differentiation GO:2000736 4 0.036
digestive tract morphogenesis GO:0048546 231 0.036
immune system process GO:0002376 241 0.036
Mouse
maternal determination of anterior posterior axis embryo GO:0008358 4 0.035
response to stress GO:0006950 263 0.035
Human Mouse Fly
convergent extension GO:0060026 118 0.035
protein k48 linked ubiquitination GO:0070936 1 0.035
mrna processing GO:0006397 14 0.035
guanosine containing compound catabolic process GO:1901069 2 0.034
regulation of reproductive process GO:2000241 4 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
response to external stimulus GO:0009605 264 0.034
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.034
Fly
hormone secretion GO:0046879 2 0.034
rna localization GO:0006403 4 0.033
erk1 and erk2 cascade GO:0070371 4 0.033
vasculature development GO:0001944 278 0.033
muscle structure development GO:0061061 196 0.033
nuclear import GO:0051170 3 0.033
fertilization GO:0009566 3 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
establishment of epithelial cell polarity GO:0090162 2 0.033
muscle cell differentiation GO:0042692 139 0.033
cytoskeleton organization GO:0007010 96 0.033
alternative mrna splicing via spliceosome GO:0000380 1 0.033
organelle assembly GO:0070925 110 0.033
production of molecular mediator of immune response GO:0002440 2 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
heart development GO:0007507 313 0.032
regulation of protein metabolic process GO:0051246 56 0.032
peptide metabolic process GO:0006518 1 0.032
antimicrobial humoral response GO:0019730 2 0.031
single organism nuclear import GO:1902593 3 0.031
regulation of biological quality GO:0065008 263 0.031
Human Mouse Fly
cellular amine metabolic process GO:0044106 2 0.031
blood vessel development GO:0001568 246 0.031
establishment of protein localization to plasma membrane GO:0090002 1 0.031
cortical cytoskeleton organization GO:0030865 1 0.030
regulation of cytokine production GO:0001817 3 0.030
Human Mouse
exocytosis GO:0006887 1 0.029
regulation of synapse organization GO:0050807 3 0.029
regulation of intracellular protein transport GO:0033157 3 0.029
protein localization to plasma membrane GO:0072659 1 0.029
chemosensory behavior GO:0007635 1 0.029
meiosis i GO:0007127 1 0.029
regulation of protein complex assembly GO:0043254 3 0.029
cell adhesion GO:0007155 40 0.029
Fly
mitotic dna integrity checkpoint GO:0044774 4 0.029
positive regulation of response to stimulus GO:0048584 80 0.029
Mouse
regulation of protein catabolic process GO:0042176 1 0.029
regulation of programmed cell death GO:0043067 101 0.029
homeostatic process GO:0042592 142 0.029
osteoclast differentiation GO:0030316 1 0.028
regulation of protein targeting GO:1903533 2 0.028
positive regulation of cellular process GO:0048522 201 0.028
rna splicing GO:0008380 16 0.028
regulation of rna metabolic process GO:0051252 224 0.028
positive regulation of cell activation GO:0050867 1 0.028
regulation of glucose import GO:0046324 1 0.028
regulation of catalytic activity GO:0050790 55 0.028
regeneration GO:0031099 91 0.027
neuron differentiation GO:0030182 353 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
spermatid differentiation GO:0048515 2 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
amine metabolic process GO:0009308 2 0.027
actin cytoskeleton organization GO:0030036 63 0.027
membrane fusion GO:0061025 2 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
positive regulation of protein polymerization GO:0032273 2 0.026
blood vessel morphogenesis GO:0048514 216 0.026
regulation of defense response to virus by host GO:0050691 1 0.026
entrainment of circadian clock GO:0009649 2 0.026
cellular component movement GO:0006928 335 0.026
mitotic dna damage checkpoint GO:0044773 4 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
response to wounding GO:0009611 116 0.026
cortical actin cytoskeleton organization GO:0030866 1 0.026
regulation of signaling GO:0023051 235 0.026
Fly
microtubule cytoskeleton organization GO:0000226 33 0.026
establishment or maintenance of cell polarity GO:0007163 29 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
ameboidal type cell migration GO:0001667 143 0.025
female sex differentiation GO:0046660 4 0.025
stem cell maintenance GO:0019827 4 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
phagocytosis GO:0006909 3 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
negative regulation of kinase activity GO:0033673 4 0.025
g2 dna damage checkpoint GO:0031572 3 0.025
Human
adherens junction organization GO:0034332 4 0.024
regulation of protein transport GO:0051223 3 0.024
response to glucose GO:0009749 3 0.024
neurotransmitter transport GO:0006836 2 0.024
response to endogenous stimulus GO:0009719 83 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
cytokinesis GO:0000910 3 0.024
primary neural tube formation GO:0014020 1 0.024
phosphorylation GO:0016310 69 0.024
positive regulation of biological process GO:0048518 253 0.024
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.024
regulation of gtp catabolic process GO:0033124 2 0.023
regulation of skeletal muscle tissue development GO:0048641 4 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
regulation of autophagy GO:0010506 3 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
Human
striated muscle cell development GO:0055002 108 0.023
positive regulation of defense response to virus by host GO:0002230 0 0.023
actin filament based process GO:0030029 64 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
regulation of meiotic cell cycle GO:0051445 1 0.022
response to radiation GO:0009314 51 0.022
posttranscriptional regulation of gene expression GO:0010608 14 0.022
Human Mouse
regulation of cell shape GO:0008360 1 0.022
Fly
somitogenesis GO:0001756 87 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
generation of neurons GO:0048699 385 0.022
female gonad development GO:0008585 4 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
development of primary female sexual characteristics GO:0046545 4 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
response to bacterium GO:0009617 58 0.022
Mouse
negative regulation of catabolic process GO:0009895 3 0.022
positive regulation of immune effector process GO:0002699 3 0.022
regulation of transport GO:0051049 45 0.021
mitotic g2 m transition checkpoint GO:0044818 3 0.021
positive regulation of cell cycle GO:0045787 3 0.021
protein localization to nucleus GO:0034504 3 0.021
negative regulation of mapk cascade GO:0043409 4 0.021
response to monosaccharide GO:0034284 3 0.021
negative regulation of nuclear division GO:0051784 3 0.021
activation of mapk activity GO:0000187 3 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
cellular response to stress GO:0033554 62 0.021
Human Fly
negative regulation of stem cell differentiation GO:2000737 2 0.020
regulation of exocytosis GO:0017157 1 0.020
angiogenesis GO:0001525 158 0.020
cellular ketone metabolic process GO:0042180 11 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
catabolic process GO:0009056 32 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
localization of cell GO:0051674 244 0.020
atp catabolic process GO:0006200 4 0.020
microtubule organizing center organization GO:0031023 1 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
regulation of photoreceptor cell differentiation GO:0046532 2 0.020
skeletal system development GO:0001501 181 0.020
regulation of neurogenesis GO:0050767 87 0.020
ribosomal small subunit biogenesis GO:0042274 2 0.020
negative regulation of developmental process GO:0051093 65 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.019
developmental growth GO:0048589 166 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
pole plasm assembly GO:0007315 4 0.019
negative regulation of intracellular signal transduction GO:1902532 22 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of cell development GO:0060284 100 0.019
neurotransmitter secretion GO:0007269 2 0.019
response to carbohydrate GO:0009743 3 0.019
embryonic limb morphogenesis GO:0030326 2 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
carbohydrate homeostasis GO:0033500 1 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
negative regulation of muscle cell differentiation GO:0051148 1 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
negative regulation of epithelial cell proliferation GO:0050680 1 0.019
regulation of transcription dna templated GO:0006355 213 0.019
positive regulation of metabolic process GO:0009893 108 0.019
tube closure GO:0060606 1 0.019
aging GO:0007568 2 0.018
Worm
developmental growth involved in morphogenesis GO:0060560 86 0.018
spermatid development GO:0007286 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
germ line stem cell division GO:0042078 1 0.018
cellular component biogenesis GO:0044085 178 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
macromolecule modification GO:0043412 111 0.018
Human Mouse
regulation of glial cell proliferation GO:0060251 4 0.018
protein polymerization GO:0051258 4 0.018
camera type eye development GO:0043010 222 0.018
regulation of cell motility GO:2000145 46 0.018
regulation of synapse assembly GO:0051963 3 0.018
positive regulation of multi organism process GO:0043902 3 0.018
negative regulation of cytokine production GO:0001818 1 0.018
system process GO:0003008 185 0.018
centrosome cycle GO:0007098 1 0.018
macromolecular complex disassembly GO:0032984 1 0.018
regulation of vesicle mediated transport GO:0060627 9 0.017
regulation of cellular response to growth factor stimulus GO:0090287 35 0.017
regulation of circadian rhythm GO:0042752 4 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
cell projection organization GO:0030030 284 0.017
regulation of cell differentiation GO:0045595 142 0.017
rna processing GO:0006396 25 0.017
ovulation cycle GO:0042698 2 0.017
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.017
cellular response to hormone stimulus GO:0032870 39 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
sensory organ development GO:0007423 393 0.017
Mouse
microtubule based process GO:0007017 60 0.017
response to uv GO:0009411 3 0.017
mononuclear cell proliferation GO:0032943 1 0.017
protein complex subunit organization GO:0071822 46 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
actin filament polymerization GO:0030041 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
somite development GO:0061053 96 0.016
cognition GO:0050890 1 0.016
cell matrix adhesion GO:0007160 4 0.016
negative regulation of metabolic process GO:0009892 86 0.016
negative regulation of map kinase activity GO:0043407 2 0.016
regulation of glucose transport GO:0010827 1 0.016
positive regulation of exocytosis GO:0045921 1 0.016
pigmentation GO:0043473 85 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
defense response to other organism GO:0098542 33 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
protein complex disassembly GO:0043241 1 0.016
regulation of gtpase activity GO:0043087 2 0.016
calcium mediated signaling GO:0019722 2 0.016
cellular localization GO:0051641 97 0.016
cellular macromolecule catabolic process GO:0044265 12 0.016
regulation of tube size GO:0035150 2 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
single organism cellular localization GO:1902580 46 0.016
synaptic vesicle transport GO:0048489 1 0.016
embryonic pattern specification GO:0009880 44 0.016
regulation of protein localization to plasma membrane GO:1903076 1 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
cellular response to nutrient levels GO:0031669 2 0.015
embryonic skeletal system development GO:0048706 97 0.015
organic acid metabolic process GO:0006082 31 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
regulation of organ growth GO:0046620 3 0.015
multi organism process GO:0051704 134 0.015
Mouse
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
centrosome duplication GO:0051298 1 0.015
mitotic sister chromatid segregation GO:0000070 6 0.015
er to golgi vesicle mediated transport GO:0006888 1 0.015
maintenance of location GO:0051235 4 0.015
mitotic g2 dna damage checkpoint GO:0007095 3 0.015
muscle tissue development GO:0060537 110 0.015
macromolecular complex assembly GO:0065003 35 0.015
locomotor rhythm GO:0045475 3 0.015
compound eye development GO:0048749 2 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
golgi vesicle transport GO:0048193 3 0.015
developmental maturation GO:0021700 34 0.015
positive regulation of translation GO:0045727 1 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
cellular response to external stimulus GO:0071496 2 0.014
organelle localization GO:0051640 49 0.014
heart looping GO:0001947 94 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
somatic muscle development GO:0007525 4 0.014
cellular amino acid biosynthetic process GO:0008652 2 0.014
tissue remodeling GO:0048771 4 0.014
ion homeostasis GO:0050801 41 0.014
protein complex assembly GO:0006461 30 0.014
cell proliferation GO:0008283 80 0.014
regulation of locomotion GO:0040012 55 0.014
negative regulation of translation GO:0017148 1 0.014
regulation of jun kinase activity GO:0043506 3 0.014
b cell activation GO:0042113 2 0.014
neurological system process GO:0050877 62 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
cellular response to starvation GO:0009267 1 0.014
somatic stem cell maintenance GO:0035019 1 0.014
epithelial structure maintenance GO:0010669 8 0.014
regulation of blood vessel size GO:0050880 2 0.014
insulin like growth factor receptor signaling pathway GO:0048009 4 0.014
specification of symmetry GO:0009799 204 0.014
response to corticosteroid GO:0031960 1 0.014
synaptic vesicle localization GO:0097479 1 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
intracellular mrna localization GO:0008298 1 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
taxis GO:0042330 109 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
divalent inorganic cation homeostasis GO:0072507 22 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
regulation of response to nutrient levels GO:0032107 1 0.013
protein complex biogenesis GO:0070271 30 0.013
protein stabilization GO:0050821 2 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
calcium ion dependent exocytosis GO:0017156 1 0.013
lamellipodium organization GO:0097581 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
oxoacid metabolic process GO:0043436 31 0.013
nucleic acid transport GO:0050657 2 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
negative regulation of multi organism process GO:0043901 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
nucleobase containing compound transport GO:0015931 2 0.013
meiotic chromosome segregation GO:0045132 3 0.013
cellular response to oxygen containing compound GO:1901701 20 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
glial cell migration GO:0008347 3 0.013
meiotic spindle organization GO:0000212 1 0.013

mapkapk2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.065
disease of metabolism DOID:0014667 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014