Danio rerio

0 known processes

letm2

leucine zipper-EF-hand containing transmembrane protein 2

letm2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.078
establishment of protein localization to organelle GO:0072594 4 0.065
biosynthetic process GO:0009058 294 0.053
system process GO:0003008 185 0.042
regulation of protein localization to nucleus GO:1900180 2 0.040
organic acid metabolic process GO:0006082 31 0.039
response to external stimulus GO:0009605 264 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
nucleoside phosphate biosynthetic process GO:1901293 21 0.037
single organism transport GO:0044765 206 0.035
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.035
aging GO:0007568 2 0.035
dicarboxylic acid transport GO:0006835 1 0.034
single organism nuclear import GO:1902593 3 0.033
nucleobase containing compound biosynthetic process GO:0034654 205 0.032
pyruvate metabolic process GO:0006090 1 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
protein targeting to nucleus GO:0044744 3 0.030
multicellular organism growth GO:0035264 4 0.030
protein localization to nucleus GO:0034504 3 0.030
larval development GO:0002164 2 0.029
single organism metabolic process GO:0044710 217 0.029
protein metabolic process GO:0019538 183 0.029
nucleotide biosynthetic process GO:0009165 21 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
intracellular signal transduction GO:0035556 85 0.028
exocytosis GO:0006887 1 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
regulation of circadian rhythm GO:0042752 4 0.027
growth GO:0040007 174 0.027
cellular biosynthetic process GO:0044249 286 0.026
protein import GO:0017038 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
phagocytosis GO:0006909 3 0.025
regulation of intracellular protein transport GO:0033157 3 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
organic substance biosynthetic process GO:1901576 289 0.024
mitochondrial transport GO:0006839 2 0.024
regulation of biosynthetic process GO:0009889 250 0.024
i kappab kinase nf kappab signaling GO:0007249 4 0.023
response to ketone GO:1901654 1 0.023
mitochondrion organization GO:0007005 4 0.023
protein import into nucleus GO:0006606 3 0.022
establishment of localization GO:0051234 244 0.022
transport GO:0006810 220 0.022
regulation of gene expression GO:0010468 265 0.022
response to biotic stimulus GO:0009607 97 0.022
golgi vesicle transport GO:0048193 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
hormone transport GO:0009914 2 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
cortical cytoskeleton organization GO:0030865 1 0.021
positive regulation of transport GO:0051050 2 0.020
multi organism cellular process GO:0044764 2 0.020
anterior posterior pattern specification GO:0009952 152 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
hormone secretion GO:0046879 2 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
endocrine process GO:0050886 2 0.020
response to other organism GO:0051707 97 0.020
amino acid transport GO:0006865 2 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
peptidyl serine phosphorylation GO:0018105 1 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
steroid hormone secretion GO:0035929 1 0.019
cytokinesis GO:0000910 3 0.019
response to chemical GO:0042221 320 0.019
negative regulation of protein complex assembly GO:0031333 1 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.018
regulation of response to stimulus GO:0048583 269 0.018
er to golgi vesicle mediated transport GO:0006888 1 0.018
neurotransmitter transport GO:0006836 2 0.018
positive regulation of neuron apoptotic process GO:0043525 1 0.018
regulation of cell communication GO:0010646 232 0.018
entrainment of circadian clock by photoperiod GO:0043153 1 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of protein transport GO:0051223 3 0.017
endoplasmic reticulum unfolded protein response GO:0030968 2 0.017
response to alkaloid GO:0043279 2 0.017
interspecies interaction between organisms GO:0044419 4 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
peptide transport GO:0015833 1 0.017
response to light stimulus GO:0009416 46 0.017
cellular amine metabolic process GO:0044106 2 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
digestive system development GO:0055123 289 0.016
regulation of protein targeting GO:1903533 2 0.016
digestive tract development GO:0048565 265 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
immune system process GO:0002376 241 0.015
regulation of tube size GO:0035150 2 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
phosphorus metabolic process GO:0006793 109 0.015
peptidyl serine modification GO:0018209 2 0.015
locomotor rhythm GO:0045475 3 0.015
positive regulation of wound healing GO:0090303 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of binding GO:0051098 3 0.015
gene expression GO:0010467 252 0.015
response to external biotic stimulus GO:0043207 97 0.015
oxoacid metabolic process GO:0043436 31 0.015
ear development GO:0043583 127 0.014
entrainment of circadian clock GO:0009649 2 0.014
organic substance transport GO:0071702 58 0.014
nuclear import GO:0051170 3 0.014
ion transport GO:0006811 114 0.014
cognition GO:0050890 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
positive regulation of cell cycle GO:0045787 3 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
positive regulation of catabolic process GO:0009896 4 0.014
response to hydrogen peroxide GO:0042542 3 0.014
regulation of neurotransmitter transport GO:0051588 1 0.013
rna biosynthetic process GO:0032774 181 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
response to topologically incorrect protein GO:0035966 2 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of reproductive process GO:2000241 4 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of muscle contraction GO:0006937 3 0.013
response to stress GO:0006950 263 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
single organism biosynthetic process GO:0044711 71 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
er nucleus signaling pathway GO:0006984 2 0.013
anion transport GO:0006820 38 0.012
regulation of metal ion transport GO:0010959 4 0.012
cation transport GO:0006812 81 0.012
central nervous system development GO:0007417 387 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
interaction with host GO:0051701 4 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of metabolic process GO:0019222 359 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
response to unfolded protein GO:0006986 2 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of inflammatory response GO:0050727 2 0.012
determination of bilateral symmetry GO:0009855 204 0.012
autophagy GO:0006914 4 0.012
amine metabolic process GO:0009308 2 0.012
ovulation cycle process GO:0022602 2 0.012
regulation of programmed cell death GO:0043067 101 0.012
regulation of wound healing GO:0061041 2 0.012
adult behavior GO:0030534 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
response to uv GO:0009411 3 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
digestive tract morphogenesis GO:0048546 231 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
nuclear transport GO:0051169 4 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of hormone secretion GO:0046883 2 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
regulation of blood vessel size GO:0050880 2 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
cell substrate adhesion GO:0031589 4 0.011
cellular response to radiation GO:0071478 4 0.011
cellular ketone metabolic process GO:0042180 11 0.011
regulation of rna metabolic process GO:0051252 224 0.011
apoptotic process GO:0006915 116 0.011
regulation of transcription dna templated GO:0006355 213 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
glucose homeostasis GO:0042593 1 0.011
p38mapk cascade GO:0038066 1 0.011
viral process GO:0016032 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
membrane fusion GO:0061025 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
regulation of multicellular organismal process GO:0051239 277 0.010
ras protein signal transduction GO:0007265 7 0.010
response to inorganic substance GO:0010035 38 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
purine ribonucleoside biosynthetic process GO:0046129 2 0.010
regulation of calcium ion transport GO:0051924 2 0.010
membrane invagination GO:0010324 1 0.010
nucleic acid templated transcription GO:0097659 181 0.010
regulation of cytokine production GO:0001817 3 0.010
coenzyme biosynthetic process GO:0009108 2 0.010
regionalization GO:0003002 274 0.010
negative regulation of catabolic process GO:0009895 3 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
rna modification GO:0009451 2 0.010
regulation of protein binding GO:0043393 3 0.010
gtp metabolic process GO:0046039 4 0.010
positive regulation of biological process GO:0048518 253 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
phosphorylation GO:0016310 69 0.010
negative regulation of multi organism process GO:0043901 3 0.010

letm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.012