Danio rerio

0 known processes

lin52

lin-52 homolog (C. elegans)

(Aliases: zgc:153771,im:7159269)

lin52 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 313 0.232
embryo development ending in birth or egg hatching GO:0009792 271 0.180
Worm
aging GO:0007568 2 0.146
ubiquitin dependent protein catabolic process GO:0006511 3 0.133
larval development GO:0002164 2 0.127
Worm
localization of cell GO:0051674 244 0.116
signal transduction GO:0007165 455 0.110
Worm
cellular component movement GO:0006928 335 0.106
mitotic g2 m transition checkpoint GO:0044818 3 0.102
cell motility GO:0048870 244 0.096
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.080
cellular macromolecule metabolic process GO:0044260 391 0.079
single organism metabolic process GO:0044710 217 0.072
protein metabolic process GO:0019538 183 0.071
organic cyclic compound metabolic process GO:1901360 301 0.070
regulation of macromolecule biosynthetic process GO:0010556 225 0.067
heterocycle metabolic process GO:0046483 290 0.065
proteasomal protein catabolic process GO:0010498 2 0.065
regulation of metabolic process GO:0019222 359 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
generation of neurons GO:0048699 385 0.061
regulation of signal transduction GO:0009966 225 0.058
Worm
embryonic organ development GO:0048568 381 0.058
heart development GO:0007507 313 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
regulation of meiotic cell cycle GO:0051445 1 0.055
modification dependent macromolecule catabolic process GO:0043632 3 0.054
single organism organelle organization GO:1902589 199 0.054
cell migration GO:0016477 237 0.053
regulation of protein ubiquitination GO:0031396 3 0.052
cellular nitrogen compound metabolic process GO:0034641 290 0.052
cell projection organization GO:0030030 284 0.052
g2 dna damage checkpoint GO:0031572 3 0.050
mitotic dna integrity checkpoint GO:0044774 4 0.049
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.049
modification dependent protein catabolic process GO:0019941 3 0.049
regulation of binding GO:0051098 3 0.048
cellular component biogenesis GO:0044085 178 0.046
negative regulation of biological process GO:0048519 304 0.046
Worm
response to external stimulus GO:0009605 264 0.045
cell projection morphogenesis GO:0048858 244 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.044
regulation of transcription dna templated GO:0006355 213 0.044
organic cyclic compound biosynthetic process GO:1901362 223 0.043
regulation of protein catabolic process GO:0042176 1 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.042
cellular protein catabolic process GO:0044257 4 0.042
regulation of cell communication GO:0010646 232 0.041
Worm
meiotic nuclear division GO:0007126 4 0.041
cytokinesis GO:0000910 3 0.041
cellular biosynthetic process GO:0044249 286 0.040
regulation of signaling GO:0023051 235 0.039
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.039
response to chemical GO:0042221 320 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
negative regulation of cell death GO:0060548 60 0.037
positive regulation of catabolic process GO:0009896 4 0.037
response to stress GO:0006950 263 0.037
single organism nuclear import GO:1902593 3 0.036
positive regulation of cell cycle GO:0045787 3 0.035
cytoskeleton dependent cytokinesis GO:0061640 3 0.035
tube morphogenesis GO:0035239 349 0.035
rna biosynthetic process GO:0032774 181 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
cell part morphogenesis GO:0032990 246 0.034
chordate embryonic development GO:0043009 271 0.034
neuron development GO:0048666 262 0.034
angiogenesis GO:0001525 158 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
protein import into nucleus GO:0006606 3 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
neuron differentiation GO:0030182 353 0.033
organelle organization GO:0006996 227 0.033
macromolecule modification GO:0043412 111 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
embryonic organ morphogenesis GO:0048562 274 0.032
transcription from rna polymerase ii promoter GO:0006366 80 0.032
reproductive process GO:0022414 40 0.032
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
regulation of response to stimulus GO:0048583 269 0.032
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
cellular response to external stimulus GO:0071496 2 0.032
cell morphogenesis GO:0000902 289 0.031
response to other organism GO:0051707 97 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
cellular component assembly GO:0022607 170 0.031
protein import GO:0017038 3 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
regulation of primary metabolic process GO:0080090 311 0.029
cell death GO:0008219 121 0.029
cellular response to nutrient levels GO:0031669 2 0.029
protein localization to nucleus GO:0034504 3 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
phosphate containing compound metabolic process GO:0006796 108 0.028
biosynthetic process GO:0009058 294 0.028
cellular component morphogenesis GO:0032989 336 0.028
stem cell proliferation GO:0072089 4 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
cellular protein metabolic process GO:0044267 129 0.027
multicellular organism growth GO:0035264 4 0.027
amine metabolic process GO:0009308 2 0.027
gene expression GO:0010467 252 0.027
transport GO:0006810 220 0.027
nuclear import GO:0051170 3 0.026
protein modification process GO:0036211 100 0.026
lateral inhibition GO:0046331 1 0.026
lipid storage GO:0019915 1 0.026
regulation of cell death GO:0010941 103 0.026
transcription dna templated GO:0006351 181 0.026
multi organism process GO:0051704 134 0.026
Worm
blood vessel development GO:0001568 246 0.025
cellular protein modification process GO:0006464 100 0.025
single organism localization GO:1902578 225 0.025
organelle assembly GO:0070925 110 0.025
protein targeting to nucleus GO:0044744 3 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.025
response to drug GO:0042493 3 0.025
phosphorus metabolic process GO:0006793 109 0.025
intracellular signal transduction GO:0035556 85 0.024
regulation of biological quality GO:0065008 263 0.024
nucleic acid metabolic process GO:0090304 244 0.023
somitogenesis GO:0001756 87 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
Worm
adult behavior GO:0030534 2 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
death GO:0016265 121 0.023
autophagy GO:0006914 4 0.022
ribosomal small subunit biogenesis GO:0042274 2 0.022
nucleic acid templated transcription GO:0097659 181 0.022
maintenance of location GO:0051235 4 0.022
regulation of gene expression GO:0010468 265 0.022
negative regulation of metabolic process GO:0009892 86 0.022
protein acylation GO:0043543 3 0.022
protein acetylation GO:0006473 2 0.021
cellular amine metabolic process GO:0044106 2 0.021
somite development GO:0061053 96 0.021
organism emergence from protective structure GO:0071684 4 0.021
negative regulation of signal transduction GO:0009968 94 0.021
Worm
regulation of apoptotic process GO:0042981 98 0.021
single organism reproductive process GO:0044702 40 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
apoptotic process GO:0006915 116 0.021
compound eye development GO:0048749 2 0.021
cellular response to stress GO:0033554 62 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
mitochondrion organization GO:0007005 4 0.021
meiotic cell cycle process GO:1903046 3 0.021
determination of left right symmetry GO:0007368 179 0.020
rna localization GO:0006403 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
regulation of developmental process GO:0050793 247 0.020
Worm
establishment of localization GO:0051234 244 0.020
regulation of biosynthetic process GO:0009889 250 0.020
mitotic g2 dna damage checkpoint GO:0007095 3 0.020
morphogenesis of an epithelium GO:0002009 333 0.019
nuclear transport GO:0051169 4 0.019
epithelial cell differentiation GO:0030855 116 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
small molecule metabolic process GO:0044281 77 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
vasculature development GO:0001944 278 0.019
cognition GO:0050890 1 0.019
rna metabolic process GO:0016070 219 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
blood vessel morphogenesis GO:0048514 216 0.018
cellular response to starvation GO:0009267 1 0.018
positive regulation of cell communication GO:0010647 56 0.018
cell aging GO:0007569 2 0.018
negative regulation of kinase activity GO:0033673 4 0.018
positive regulation of transport GO:0051050 2 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of programmed cell death GO:0043067 101 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
regulation of rna metabolic process GO:0051252 224 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
positive regulation of metabolic process GO:0009893 108 0.017
specification of symmetry GO:0009799 204 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.016
hatching GO:0035188 4 0.016
regulation of synapse organization GO:0050807 3 0.016
cellular response to dna damage stimulus GO:0006974 24 0.016
macroautophagy GO:0016236 1 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
gtp catabolic process GO:0006184 2 0.016
immune system process GO:0002376 241 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
pharyngeal muscle development GO:0043282 4 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
regulation of protein targeting GO:1903533 2 0.015
cell fate specification GO:0001708 68 0.015
neuroblast proliferation GO:0007405 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
energy reserve metabolic process GO:0006112 2 0.015
negative regulation of signaling GO:0023057 96 0.015
Worm
regulation of protein transport GO:0051223 3 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
organic substance biosynthetic process GO:1901576 289 0.015
regulation of synapse assembly GO:0051963 3 0.015
dna templated transcription elongation GO:0006354 3 0.015
mitotic nuclear division GO:0007067 18 0.015
anterior posterior pattern specification GO:0009952 152 0.015
cell projection assembly GO:0030031 64 0.015
regulation of cellular component organization GO:0051128 86 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
mitotic cytokinesis GO:0000281 3 0.015
system process GO:0003008 185 0.015
regulation of receptor activity GO:0010469 2 0.015
oxoacid metabolic process GO:0043436 31 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
organic acid metabolic process GO:0006082 31 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
neuron projection development GO:0031175 180 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
Worm
negative regulation of protein kinase activity GO:0006469 4 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
female meiotic division GO:0007143 2 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
homeostatic process GO:0042592 142 0.014
regulation of embryonic development GO:0045995 47 0.014
response to biotic stimulus GO:0009607 97 0.014
regulation of response to stress GO:0080134 36 0.014
digestive system development GO:0055123 289 0.014
eye development GO:0001654 277 0.014
heart morphogenesis GO:0003007 156 0.014
sensory organ development GO:0007423 393 0.014
neuron projection morphogenesis GO:0048812 161 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
Worm
cellular response to extracellular stimulus GO:0031668 2 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
digestive tract development GO:0048565 265 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
muscle structure development GO:0061061 196 0.013
axonogenesis GO:0007409 152 0.013
proteolysis GO:0006508 38 0.013
tube closure GO:0060606 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
sex determination GO:0007530 1 0.013
cellular component disassembly GO:0022411 1 0.013
negative regulation of cellular process GO:0048523 283 0.013
Worm
regulation of metal ion transport GO:0010959 4 0.013
programmed cell death GO:0012501 119 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
chemotaxis GO:0006935 104 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.012
response to external biotic stimulus GO:0043207 97 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
regulation of cell projection assembly GO:0060491 4 0.012
cilium morphogenesis GO:0060271 85 0.012
protein secretion GO:0009306 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
protein phosphorylation GO:0006468 47 0.012
single organism membrane fusion GO:0044801 2 0.012
peptidyl serine modification GO:0018209 2 0.012
actin filament based movement GO:0030048 1 0.012
negative regulation of cell communication GO:0010648 96 0.012
Worm
phosphorylation GO:0016310 69 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
single organism transport GO:0044765 206 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of reproductive process GO:2000241 4 0.012
growth GO:0040007 174 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
dna biosynthetic process GO:0071897 3 0.012
camera type eye development GO:0043010 222 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.011
actin mediated cell contraction GO:0070252 1 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of transporter activity GO:0032409 2 0.011
cell proliferation GO:0008283 80 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
gland development GO:0048732 143 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
neurological system process GO:0050877 62 0.011
meiotic chromosome segregation GO:0045132 3 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
protein dephosphorylation GO:0006470 3 0.011
phagocytosis GO:0006909 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
spermatid development GO:0007286 2 0.011
primary neural tube formation GO:0014020 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
protein localization to plasma membrane GO:0072659 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
gtp metabolic process GO:0046039 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
atp catabolic process GO:0006200 4 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
multi organism reproductive process GO:0044703 36 0.010
Worm
negative regulation of stem cell differentiation GO:2000737 2 0.010
regulation of cell cycle GO:0051726 52 0.010
catabolic process GO:0009056 32 0.010
developmental process involved in reproduction GO:0003006 27 0.010
mesenchyme development GO:0060485 127 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
cilium organization GO:0044782 71 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of cell shape GO:0008360 1 0.010
regulation of protein binding GO:0043393 3 0.010
positive regulation of jnk cascade GO:0046330 3 0.010

lin52 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.014
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.012