Danio rerio

0 known processes

psmd1

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

(Aliases: MGC55818,zgc:55818)

psmd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.853
Worm
ubiquitin dependent protein catabolic process GO:0006511 3 0.742
Yeast
modification dependent macromolecule catabolic process GO:0043632 3 0.641
Yeast
proteasomal protein catabolic process GO:0010498 2 0.454
aging GO:0007568 2 0.293
Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.282
cellular protein metabolic process GO:0044267 129 0.269
Yeast
lateral inhibition GO:0046331 1 0.241
modification dependent protein catabolic process GO:0019941 3 0.228
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.209
Yeast
regulation of biological quality GO:0065008 263 0.188
cellular protein catabolic process GO:0044257 4 0.147
Yeast
positive regulation of biological process GO:0048518 253 0.123
positive regulation of catabolic process GO:0009896 4 0.108
regulation of protein catabolic process GO:0042176 1 0.103
cellular component assembly GO:0022607 170 0.092
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.091
multicellular organism growth GO:0035264 4 0.089
biosynthetic process GO:0009058 294 0.089
gene expression GO:0010467 252 0.086
establishment of localization GO:0051234 244 0.084
maintenance of location GO:0051235 4 0.082
response to stress GO:0006950 263 0.081
cellular component biogenesis GO:0044085 178 0.079
Yeast
macromolecule biosynthetic process GO:0009059 227 0.079
mrna polyadenylation GO:0006378 2 0.078
regulation of multicellular organism growth GO:0040014 4 0.077
regulation of metabolic process GO:0019222 359 0.077
cellular localization GO:0051641 97 0.076
cellular nitrogen compound metabolic process GO:0034641 290 0.076
organic substance catabolic process GO:1901575 28 0.075
Yeast
macromolecule catabolic process GO:0009057 15 0.075
Yeast
single organism localization GO:1902578 225 0.069
cellular catabolic process GO:0044248 27 0.068
Yeast
fertilization GO:0009566 3 0.067
death GO:0016265 121 0.066
Worm
signal transduction GO:0007165 455 0.064
organism emergence from protective structure GO:0071684 4 0.064
cellular macromolecule biosynthetic process GO:0034645 224 0.063
embryo development ending in birth or egg hatching GO:0009792 271 0.063
Worm
heterocycle biosynthetic process GO:0018130 215 0.060
regulation of protein metabolic process GO:0051246 56 0.060
regulation of response to stimulus GO:0048583 269 0.059
organic substance biosynthetic process GO:1901576 289 0.057
ribonucleoside monophosphate catabolic process GO:0009158 4 0.055
hatching GO:0035188 4 0.055
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.054
organonitrogen compound metabolic process GO:1901564 74 0.054
protein complex assembly GO:0006461 30 0.054
Yeast
response to chemical GO:0042221 320 0.052
nucleic acid metabolic process GO:0090304 244 0.052
regulation of macromolecule metabolic process GO:0060255 317 0.052
regulation of molecular function GO:0065009 70 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
developmental growth GO:0048589 166 0.050
transcription from rna polymerase ii promoter GO:0006366 80 0.050
regulation of peptidase activity GO:0052547 23 0.048
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.048
mitochondrion organization GO:0007005 4 0.048
cellular biosynthetic process GO:0044249 286 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
positive regulation of transport GO:0051050 2 0.046
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.045
protein metabolic process GO:0019538 183 0.045
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.044
transport GO:0006810 220 0.044
cellular macromolecule catabolic process GO:0044265 12 0.043
Yeast
regulation of cellular metabolic process GO:0031323 320 0.042
protein polyubiquitination GO:0000209 4 0.042
spindle assembly involved in mitosis GO:0090307 1 0.041
heterocycle metabolic process GO:0046483 290 0.041
single organism metabolic process GO:0044710 217 0.041
cell death GO:0008219 121 0.041
Worm
locomotor rhythm GO:0045475 3 0.040
single fertilization GO:0007338 3 0.040
protein import GO:0017038 3 0.040
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.039
macromolecular complex assembly GO:0065003 35 0.039
Yeast
immune system process GO:0002376 241 0.038
chordate embryonic development GO:0043009 271 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
Yeast
single organism transport GO:0044765 206 0.037
regulation of catalytic activity GO:0050790 55 0.037
small molecule metabolic process GO:0044281 77 0.036
regulation of proteolysis GO:0030162 24 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
regulation of protein localization to nucleus GO:1900180 2 0.036
proteolysis GO:0006508 38 0.036
Yeast
regulation of protein transport GO:0051223 3 0.035
nucleoside monophosphate catabolic process GO:0009125 4 0.035
regulation of primary metabolic process GO:0080090 311 0.035
regulation of cellular protein metabolic process GO:0032268 52 0.035
meiotic nuclear division GO:0007126 4 0.034
protein localization to nucleus GO:0034504 3 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
positive regulation of cellular process GO:0048522 201 0.032
growth GO:0040007 174 0.032
negative regulation of cellular process GO:0048523 283 0.032
rrna catabolic process GO:0016075 1 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
regulation of apoptotic process GO:0042981 98 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
regulation of developmental process GO:0050793 247 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
gtp catabolic process GO:0006184 2 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
protein import into nucleus GO:0006606 3 0.029
organic substance transport GO:0071702 58 0.028
neuron differentiation GO:0030182 353 0.028
regulation of nucleocytoplasmic transport GO:0046822 2 0.028
regulation of mrna processing GO:0050684 3 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of protein ubiquitination GO:0031396 3 0.027
single organism nuclear import GO:1902593 3 0.027
protein n linked glycosylation GO:0006487 1 0.027
positive regulation of multicellular organismal process GO:0051240 52 0.027
rna biosynthetic process GO:0032774 181 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
cellular component disassembly GO:0022411 1 0.026
homeostatic process GO:0042592 142 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
regulation of cellular protein catabolic process GO:1903362 1 0.026
rna metabolic process GO:0016070 219 0.025
protein k63 linked ubiquitination GO:0070534 2 0.025
spindle assembly GO:0051225 2 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
programmed cell death GO:0012501 119 0.024
Worm
cell morphogenesis GO:0000902 289 0.024
cell fate commitment GO:0045165 99 0.024
locomotion GO:0040011 313 0.023
nucleus organization GO:0006997 7 0.023
regulation of programmed cell death GO:0043067 101 0.022
oxoacid metabolic process GO:0043436 31 0.022
cellular amine metabolic process GO:0044106 2 0.022
cell migration GO:0016477 237 0.022
negative regulation of mitosis GO:0045839 3 0.022
positive regulation of developmental process GO:0051094 50 0.022
compound eye development GO:0048749 2 0.022
single organism membrane fusion GO:0044801 2 0.022
apoptotic process GO:0006915 116 0.021
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
multi organism process GO:0051704 134 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
phosphorus metabolic process GO:0006793 109 0.020
regulation of protein binding GO:0043393 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of signaling GO:0023051 235 0.020
catabolic process GO:0009056 32 0.020
Yeast
regulation of protein complex assembly GO:0043254 3 0.020
negative regulation of translation GO:0017148 1 0.020
eye development GO:0001654 277 0.020
negative regulation of nuclear division GO:0051784 3 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
protein localization GO:0008104 40 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
rna localization GO:0006403 4 0.020
protein targeting to nucleus GO:0044744 3 0.020
protein complex biogenesis GO:0070271 30 0.020
Yeast
generation of neurons GO:0048699 385 0.020
reproduction GO:0000003 40 0.020
Worm
meiotic spindle organization GO:0000212 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
mitotic sister chromatid segregation GO:0000070 6 0.019
sensory organ development GO:0007423 393 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
cellular amide metabolic process GO:0043603 4 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
regulation of homeostatic process GO:0032844 9 0.019
regulation of hydrolase activity GO:0051336 28 0.019
carbohydrate derivative metabolic process GO:1901135 61 0.018
protein complex subunit organization GO:0071822 46 0.018
Yeast
regulation of nucleoside metabolic process GO:0009118 2 0.018
ribonucleotide metabolic process GO:0009259 27 0.018
atp catabolic process GO:0006200 4 0.018
cellular response to dna damage stimulus GO:0006974 24 0.018
macromolecule localization GO:0033036 54 0.018
mrna export from nucleus GO:0006406 1 0.018
nuclear transport GO:0051169 4 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
rna 3 end processing GO:0031123 2 0.017
dna metabolic process GO:0006259 27 0.017
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.017
posttranscriptional regulation of gene expression GO:0010608 14 0.017
interspecies interaction between organisms GO:0044419 4 0.016
cell cell signaling GO:0007267 52 0.016
cranial nerve development GO:0021545 42 0.016
response to topologically incorrect protein GO:0035966 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of glucose transport GO:0010827 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
pigmentation GO:0043473 85 0.016
autophagy GO:0006914 4 0.016
nuclear pore organization GO:0006999 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.016
golgi vesicle transport GO:0048193 3 0.016
regulation of cell communication GO:0010646 232 0.016
nucleoside phosphate metabolic process GO:0006753 28 0.015
cell cell signaling involved in cell fate commitment GO:0045168 12 0.015
mitotic nuclear division GO:0007067 18 0.015
cellular macromolecular complex assembly GO:0034622 24 0.015
Yeast
head development GO:0060322 303 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
meiotic cell cycle process GO:1903046 3 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of binding GO:0051098 3 0.015
positive regulation of protein metabolic process GO:0051247 23 0.015
cellular response to external stimulus GO:0071496 2 0.015
regulation of protein targeting GO:1903533 2 0.015
mrna 3 end processing GO:0031124 2 0.015
negative regulation of proteolysis GO:0045861 10 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.014
negative regulation of ras protein signal transduction GO:0046580 1 0.014
dna templated transcription elongation GO:0006354 3 0.014
regulation of signal transduction GO:0009966 225 0.014
skeletal system development GO:0001501 181 0.014
regulation of developmental growth GO:0048638 38 0.014
organelle localization GO:0051640 49 0.014
nuclear import GO:0051170 3 0.014
regulation of growth GO:0040008 42 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
positive regulation of catalytic activity GO:0043085 25 0.014
positive regulation of peptidase activity GO:0010952 10 0.014
negative regulation of metabolic process GO:0009892 86 0.014
neuroblast proliferation GO:0007405 2 0.014
protein polymerization GO:0051258 4 0.014
negative regulation of chromosome organization GO:2001251 1 0.013
protein depolymerization GO:0051261 1 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of cell death GO:0010941 103 0.013
response to biotic stimulus GO:0009607 97 0.013
cellular response to stress GO:0033554 62 0.013
negative regulation of biological process GO:0048519 304 0.013
positive regulation of metabolic process GO:0009893 108 0.013
protein modification by small protein removal GO:0070646 1 0.013
establishment of rna localization GO:0051236 3 0.013
membrane fusion GO:0061025 2 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
response to external stimulus GO:0009605 264 0.013
mrna transport GO:0051028 2 0.013
positive regulation of endopeptidase activity GO:0010950 10 0.013
rna polyadenylation GO:0043631 2 0.013
single organism cellular localization GO:1902580 46 0.013
amine metabolic process GO:0009308 2 0.013
positive regulation of proteolysis GO:0045862 10 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
protein secretion GO:0009306 1 0.012
positive regulation of molecular function GO:0044093 33 0.012
positive regulation of histone modification GO:0031058 1 0.012
phagocytosis GO:0006909 3 0.012
negative regulation of cell death GO:0060548 60 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
response to organic substance GO:0010033 153 0.011
peptide metabolic process GO:0006518 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
cytokinesis GO:0000910 3 0.011
establishment of localization in cell GO:0051649 77 0.011
nucleic acid transport GO:0050657 2 0.011
negative regulation of cellular protein metabolic process GO:0032269 16 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
response to hexose GO:0009746 3 0.011
establishment of vesicle localization GO:0051650 24 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
cytoplasm organization GO:0007028 4 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
mitotic metaphase plate congression GO:0007080 1 0.011
single organism organelle organization GO:1902589 199 0.011
cell cell recognition GO:0009988 1 0.011
regulation of chromosome segregation GO:0051983 1 0.011
stem cell division GO:0017145 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
regionalization GO:0003002 274 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
embryonic skeletal system development GO:0048706 97 0.011
positive regulation of signal transduction GO:0009967 56 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
mitotic cell cycle GO:0000278 64 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
ncrna catabolic process GO:0034661 1 0.010
cell cycle process GO:0022402 53 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
fin regeneration GO:0031101 51 0.010
double strand break repair GO:0006302 3 0.010
nuclear envelope organization GO:0006998 2 0.010
cell motility GO:0048870 244 0.010
lipid storage GO:0019915 1 0.010
stem cell proliferation GO:0072089 4 0.010
cellular protein complex assembly GO:0043623 19 0.010
Yeast
positive regulation of chromatin modification GO:1903310 1 0.010
nucleic acid templated transcription GO:0097659 181 0.010
carbohydrate derivative biosynthetic process GO:1901137 43 0.010
regulation of inflammatory response GO:0050727 2 0.010
organelle fission GO:0048285 23 0.010

psmd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
nervous system disease DOID:863 0 0.080
central nervous system disease DOID:331 0 0.037
tauopathy DOID:680 0 0.037
neurodegenerative disease DOID:1289 0 0.037