Danio rerio

0 known processes

plekhg4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

(Aliases: wu:fd99e06)

plekhg4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endothelial cell fate commitment GO:0060839 3 0.734
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.548
lymphatic endothelial cell fate commitment GO:0060838 1 0.540
sensory organ development GO:0007423 393 0.515
cellular biosynthetic process GO:0044249 286 0.502
signal transduction GO:0007165 455 0.448
biosynthetic process GO:0009058 294 0.438
digestive system development GO:0055123 289 0.432
transcription from rna polymerase iii promoter GO:0006383 1 0.421
nitrogen compound metabolic process GO:0006807 319 0.419
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.393
intracellular receptor signaling pathway GO:0030522 30 0.357
head development GO:0060322 303 0.334
regulation of rna metabolic process GO:0051252 224 0.329
organic cyclic compound biosynthetic process GO:1901362 223 0.313
central nervous system development GO:0007417 387 0.306
heterocycle biosynthetic process GO:0018130 215 0.290
lymph vessel development GO:0001945 27 0.272
lymphangiogenesis GO:0001946 25 0.271
regulation of fatty acid metabolic process GO:0019217 1 0.264
establishment of localization GO:0051234 244 0.250
generation of neurons GO:0048699 385 0.246
regulation of transcription dna templated GO:0006355 213 0.240
ear development GO:0043583 127 0.234
gene expression GO:0010467 252 0.229
lymphatic endothelial cell differentiation GO:0060836 1 0.223
negative regulation of cellular biosynthetic process GO:0031327 55 0.216
negative regulation of gene expression GO:0010629 65 0.211
cellular nitrogen compound metabolic process GO:0034641 290 0.209
lymph vessel morphogenesis GO:0036303 25 0.209
regulation of metabolic process GO:0019222 359 0.199
camera type eye development GO:0043010 222 0.193
regulation of nucleic acid templated transcription GO:1903506 213 0.191
regulation of gene expression GO:0010468 265 0.190
cell surface receptor signaling pathway GO:0007166 325 0.190
lipid storage GO:0019915 1 0.188
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.181
regulation of response to stimulus GO:0048583 269 0.176
negative regulation of biosynthetic process GO:0009890 55 0.172
negative regulation of cell communication GO:0010648 96 0.168
aromatic compound biosynthetic process GO:0019438 217 0.168
epithelial cell differentiation GO:0030855 116 0.165
larval development GO:0002164 2 0.164
regulation of macromolecule biosynthetic process GO:0010556 225 0.157
nucleic acid templated transcription GO:0097659 181 0.152
positive regulation of biological process GO:0048518 253 0.149
negative regulation of cellular process GO:0048523 283 0.147
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.146
kidney development GO:0001822 92 0.146
regulation of primary metabolic process GO:0080090 311 0.141
rna biosynthetic process GO:0032774 181 0.140
organic substance biosynthetic process GO:1901576 289 0.138
neuron development GO:0048666 262 0.137
skeletal muscle tissue development GO:0007519 67 0.136
negative regulation of rna metabolic process GO:0051253 48 0.135
nucleic acid metabolic process GO:0090304 244 0.133
regulation of macromolecule metabolic process GO:0060255 317 0.132
transcription dna templated GO:0006351 181 0.132
stem cell proliferation GO:0072089 4 0.131
regulation of signaling GO:0023051 235 0.130
morphogenesis of an epithelium GO:0002009 333 0.126
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.124
neural tube development GO:0021915 62 0.121
cellular nitrogen compound biosynthetic process GO:0044271 218 0.121
response to organic substance GO:0010033 153 0.114
negative regulation of metabolic process GO:0009892 86 0.113
cell death GO:0008219 121 0.110
rna metabolic process GO:0016070 219 0.110
heterocycle metabolic process GO:0046483 290 0.106
macromolecule biosynthetic process GO:0009059 227 0.106
axon ensheathment in central nervous system GO:0032291 2 0.105
negative regulation of cellular metabolic process GO:0031324 77 0.103
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.101
inner ear development GO:0048839 126 0.101
regulation of cellular biosynthetic process GO:0031326 245 0.097
neuroblast proliferation GO:0007405 2 0.097
single organism localization GO:1902578 225 0.097
axonogenesis GO:0007409 152 0.096
neural tube formation GO:0001841 16 0.095
brain development GO:0007420 293 0.094
notochord development GO:0030903 54 0.093
regulation of biosynthetic process GO:0009889 250 0.092
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.090
eye development GO:0001654 277 0.089
positive regulation of transport GO:0051050 2 0.089
negative regulation of signal transduction GO:0009968 94 0.087
positive regulation of gene expression GO:0010628 71 0.086
cellular aromatic compound metabolic process GO:0006725 295 0.086
neuron differentiation GO:0030182 353 0.086
negative regulation of signaling GO:0023057 96 0.085
ear morphogenesis GO:0042471 64 0.085
positive regulation of cellular process GO:0048522 201 0.085
nucleobase containing compound biosynthetic process GO:0034654 205 0.084
embryonic organ development GO:0048568 381 0.083
notch signaling pathway GO:0007219 35 0.083
negative regulation of biological process GO:0048519 304 0.082
transport GO:0006810 220 0.082
negative regulation of nucleic acid templated transcription GO:1903507 45 0.081
forebrain development GO:0030900 96 0.081
regulation of biological quality GO:0065008 263 0.081
regulation of signal transduction GO:0009966 225 0.080
negative regulation of transcription dna templated GO:0045892 45 0.080
response to stress GO:0006950 263 0.079
biological adhesion GO:0022610 40 0.079
positive regulation of rna biosynthetic process GO:1902680 57 0.075
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.075
cellular macromolecule biosynthetic process GO:0034645 224 0.075
localization of cell GO:0051674 244 0.074
neuron projection development GO:0031175 180 0.074
negative regulation of macromolecule metabolic process GO:0010605 76 0.074
regulation of apoptotic process GO:0042981 98 0.073
erk1 and erk2 cascade GO:0070371 4 0.073
organic cyclic compound metabolic process GO:1901360 301 0.073
organelle organization GO:0006996 227 0.072
cellular macromolecule metabolic process GO:0044260 391 0.071
sensory organ morphogenesis GO:0090596 200 0.071
gland development GO:0048732 143 0.071
cellular component morphogenesis GO:0032989 336 0.071
response to chemical GO:0042221 320 0.070
digestive tract development GO:0048565 265 0.070
regulation of developmental process GO:0050793 247 0.069
regulation of cell communication GO:0010646 232 0.068
transcription from rna polymerase ii promoter GO:0006366 80 0.066
negative regulation of rna biosynthetic process GO:1902679 45 0.066
somitogenesis GO:0001756 87 0.066
tube morphogenesis GO:0035239 349 0.065
regulation of skeletal muscle fiber development GO:0048742 2 0.064
cell fate commitment GO:0045165 99 0.064
regulation of skeletal muscle tissue development GO:0048641 4 0.064
appendage development GO:0048736 80 0.064
cellular response to oxygen levels GO:0071453 1 0.063
carboxylic acid metabolic process GO:0019752 22 0.063
nucleobase containing compound metabolic process GO:0006139 274 0.062
somite development GO:0061053 96 0.062
stem cell maintenance GO:0019827 4 0.061
blood vessel development GO:0001568 246 0.061
protein import into nucleus GO:0006606 3 0.061
lateral line system development GO:0048925 76 0.061
oxoacid metabolic process GO:0043436 31 0.060
cellular response to xenobiotic stimulus GO:0071466 35 0.059
regulation of cellular ketone metabolic process GO:0010565 7 0.058
gastrulation GO:0007369 208 0.058
response to external stimulus GO:0009605 264 0.058
sensory system development GO:0048880 76 0.058
primary neural tube formation GO:0014020 1 0.057
regulation of cellular metabolic process GO:0031323 320 0.057
organic acid metabolic process GO:0006082 31 0.057
detection of temperature stimulus involved in sensory perception GO:0050961 0 0.057
regulation of establishment of protein localization GO:0070201 4 0.057
cellular component biogenesis GO:0044085 178 0.057
response to lipid GO:0033993 60 0.056
muscle structure development GO:0061061 196 0.056
maintenance of location GO:0051235 4 0.055
embryo development ending in birth or egg hatching GO:0009792 271 0.055
cellular component assembly GO:0022607 170 0.054
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
cytoskeleton organization GO:0007010 96 0.054
regulation of chemotaxis GO:0050920 18 0.053
cellular response to chemical stimulus GO:0070887 157 0.053
gliogenesis GO:0042063 45 0.053
single organism metabolic process GO:0044710 217 0.052
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.051
regulation of multicellular organismal process GO:0051239 277 0.051
digestive tract morphogenesis GO:0048546 231 0.051
proximal distal pattern formation GO:0009954 1 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.051
positive regulation of protein kinase b signaling GO:0051897 1 0.050
regulation of rna biosynthetic process GO:2001141 213 0.050
extracellular structure organization GO:0043062 27 0.050
regulation of anatomical structure morphogenesis GO:0022603 130 0.049
immune system process GO:0002376 241 0.049
vasculature development GO:0001944 278 0.049
renal system development GO:0072001 94 0.048
negative regulation of response to stimulus GO:0048585 104 0.048
embryonic organ morphogenesis GO:0048562 274 0.048
apoptotic process GO:0006915 116 0.048
epidermis development GO:0008544 48 0.048
aging GO:0007568 2 0.048
lateral inhibition GO:0046331 1 0.047
epithelial tube morphogenesis GO:0060562 148 0.046
fin morphogenesis GO:0033334 53 0.046
eye morphogenesis GO:0048592 144 0.046
regulation of multicellular organismal development GO:2000026 223 0.046
positive regulation of rna metabolic process GO:0051254 59 0.045
cellular ketone metabolic process GO:0042180 11 0.045
phagocytosis GO:0006909 3 0.044
positive regulation of cellular biosynthetic process GO:0031328 68 0.044
ameboidal type cell migration GO:0001667 143 0.044
embryonic limb morphogenesis GO:0030326 2 0.043
protein localization to nucleus GO:0034504 3 0.043
positive regulation of cell cycle GO:0045787 3 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.042
response to oxygen containing compound GO:1901700 55 0.042
developmental growth GO:0048589 166 0.041
response to endogenous stimulus GO:0009719 83 0.040
cell morphogenesis GO:0000902 289 0.040
positive regulation of response to stimulus GO:0048584 80 0.040
retina morphogenesis in camera type eye GO:0060042 79 0.039
regulation of erk1 and erk2 cascade GO:0070372 4 0.038
regulation of myotube differentiation GO:0010830 2 0.038
regulation of inflammatory response GO:0050727 2 0.037
retina development in camera type eye GO:0060041 146 0.036
regulation of cell death GO:0010941 103 0.036
single organism organelle organization GO:1902589 199 0.036
protein processing GO:0016485 12 0.036
somite specification GO:0001757 12 0.035
regulation of localization GO:0032879 104 0.035
epidermal cell fate specification GO:0009957 4 0.035
detection of temperature stimulus GO:0016048 0 0.035
central nervous system myelination GO:0022010 2 0.035
tube closure GO:0060606 1 0.035
regulation of cytokine production GO:0001817 3 0.035
neurological system process GO:0050877 62 0.035
cell migration GO:0016477 237 0.034
regulation of behavior GO:0050795 24 0.034
morphogenesis of embryonic epithelium GO:0016331 30 0.034
cell projection organization GO:0030030 284 0.034
regulation of cell development GO:0060284 100 0.034
inner ear morphogenesis GO:0042472 63 0.034
camera type eye morphogenesis GO:0048593 108 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
axon development GO:0061564 166 0.033
axon guidance GO:0007411 86 0.032
mesenchymal cell development GO:0014031 78 0.032
regulation of protein transport GO:0051223 3 0.032
cell cycle g1 s phase transition GO:0044843 1 0.032
positive regulation of cell communication GO:0010647 56 0.032
mesoderm development GO:0007498 88 0.032
urogenital system development GO:0001655 97 0.032
single organism transport GO:0044765 206 0.031
mesenchyme development GO:0060485 127 0.031
protein import GO:0017038 3 0.031
system process GO:0003008 185 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
cognition GO:0050890 1 0.031
response to abiotic stimulus GO:0009628 122 0.031
response to xenobiotic stimulus GO:0009410 45 0.031
negative regulation of response to cytokine stimulus GO:0060761 2 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.030
muscle cell differentiation GO:0042692 139 0.030
cellular component movement GO:0006928 335 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
positive regulation of cellular metabolic process GO:0031325 94 0.030
peptidyl lysine acetylation GO:0018394 2 0.029
positive regulation of biosynthetic process GO:0009891 68 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
cranial nerve development GO:0021545 42 0.029
connective tissue development GO:0061448 99 0.029
blood vessel morphogenesis GO:0048514 216 0.029
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.028
blood vessel endothelial cell migration GO:0043534 18 0.028
organic substance transport GO:0071702 58 0.028
regulation of programmed cell death GO:0043067 101 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
amine metabolic process GO:0009308 2 0.028
cell adhesion GO:0007155 40 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.027
positive regulation of metabolic process GO:0009893 108 0.027
cellular response to external stimulus GO:0071496 2 0.026
homeostatic process GO:0042592 142 0.026
spermatid differentiation GO:0048515 2 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
anterior posterior pattern specification GO:0009952 152 0.026
g1 s transition of mitotic cell cycle GO:0000082 1 0.026
cell motility GO:0048870 244 0.026
cell migration involved in gastrulation GO:0042074 79 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.026
regulation of cellular component organization GO:0051128 86 0.025
macromolecule localization GO:0033036 54 0.025
death GO:0016265 121 0.025
internal protein amino acid acetylation GO:0006475 2 0.025
response to vitamin GO:0033273 3 0.025
female gonad development GO:0008585 4 0.025
regulation of stem cell proliferation GO:0072091 2 0.025
positive regulation of map kinase activity GO:0043406 3 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
neutrophil migration GO:1990266 10 0.024
positive regulation of signal transduction GO:0009967 56 0.024
response to wounding GO:0009611 116 0.024
cell substrate adhesion GO:0031589 4 0.024
wnt signaling pathway GO:0016055 80 0.024
retinoic acid receptor signaling pathway GO:0048384 16 0.024
enzyme linked receptor protein signaling pathway GO:0007167 106 0.023
response to nutrient GO:0007584 3 0.023
protein modification process GO:0036211 100 0.023
multicellular organism growth GO:0035264 4 0.023
sprouting angiogenesis GO:0002040 53 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
protein targeting to nucleus GO:0044744 3 0.023
wound healing GO:0042060 90 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
positive regulation of transcription dna templated GO:0045893 57 0.023
positive regulation of developmental process GO:0051094 50 0.023
cell projection morphogenesis GO:0048858 244 0.022
chemotaxis GO:0006935 104 0.022
ectodermal placode morphogenesis GO:0071697 32 0.022
negative regulation of epithelial cell migration GO:0010633 1 0.022
small molecule metabolic process GO:0044281 77 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
neuron projection morphogenesis GO:0048812 161 0.022
positive regulation of cell adhesion GO:0045785 1 0.022
regulation of locomotion GO:0040012 55 0.022
cell projection assembly GO:0030031 64 0.022
odontogenesis of dentin containing tooth GO:0042475 1 0.021
cellular lipid metabolic process GO:0044255 36 0.021
locomotion GO:0040011 313 0.021
positive regulation of cytokine production GO:0001819 2 0.021
neuron projection guidance GO:0097485 86 0.021
intracellular signal transduction GO:0035556 85 0.021
sensory perception of pain GO:0019233 1 0.021
regulation of organ growth GO:0046620 3 0.021
programmed cell death GO:0012501 119 0.021
positive regulation of immune system process GO:0002684 17 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
protein localization GO:0008104 40 0.020
ectodermal placode development GO:0071696 37 0.020
actin filament based process GO:0030029 64 0.020
embryonic epithelial tube formation GO:0001838 17 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
skeletal system development GO:0001501 181 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
photoreceptor cell differentiation GO:0046530 55 0.020
behavior GO:0007610 74 0.020
stem cell development GO:0048864 82 0.019
lateral line development GO:0048882 66 0.019
hematopoietic stem cell migration GO:0035701 4 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
positive regulation of locomotion GO:0040017 14 0.019
growth GO:0040007 174 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
neuron migration GO:0001764 22 0.019
negative regulation of apoptotic process GO:0043066 55 0.019
regulation of protein targeting GO:1903533 2 0.019
sex determination GO:0007530 1 0.019
striated muscle cell development GO:0055002 108 0.018
cilium morphogenesis GO:0060271 85 0.018
regulation of cell motility GO:2000145 46 0.018
regulation of cell activation GO:0050865 1 0.018
midbrain development GO:0030901 28 0.018
stem cell differentiation GO:0048863 117 0.018
multicellular organismal metabolic process GO:0044236 2 0.018
positive regulation of secretion GO:0051047 1 0.018
protein metabolic process GO:0019538 183 0.018
angiogenesis GO:0001525 158 0.018
skin development GO:0043588 54 0.018
regulation of stem cell differentiation GO:2000736 4 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.018
positive regulation of cellular component movement GO:0051272 11 0.018
muscle organ development GO:0007517 101 0.017
dna biosynthetic process GO:0071897 3 0.017
collagen metabolic process GO:0032963 2 0.017
regulation of reproductive process GO:2000241 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
negative regulation of defense response GO:0031348 2 0.017
protein acetylation GO:0006473 2 0.017
epithelial cell fate commitment GO:0072148 11 0.017
protein secretion GO:0009306 1 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
single organismal cell cell adhesion GO:0016337 29 0.017
stem cell division GO:0017145 1 0.017
regulation of immune system process GO:0002682 34 0.017
nuclear import GO:0051170 3 0.017
regulation of blood vessel size GO:0050880 2 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
positive regulation of programmed cell death GO:0043068 29 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
transmission of nerve impulse GO:0019226 19 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
positive regulation of muscle tissue development GO:1901863 1 0.016
multicellular organismal signaling GO:0035637 22 0.016
negative regulation of cytokine production GO:0001818 1 0.016
fin development GO:0033333 77 0.016
embryonic camera type eye development GO:0031076 29 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
specification of symmetry GO:0009799 204 0.016
sensory perception GO:0007600 39 0.016
embryonic pattern specification GO:0009880 44 0.016
glial cell migration GO:0008347 3 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
midbrain hindbrain boundary development GO:0030917 23 0.016
regulation of cell projection assembly GO:0060491 4 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
neuron fate commitment GO:0048663 26 0.016
cell proliferation in forebrain GO:0021846 3 0.016
hemopoiesis GO:0030097 183 0.016
regulation of cell morphogenesis GO:0022604 42 0.016
somatic muscle development GO:0007525 4 0.015
regulation of cell differentiation GO:0045595 142 0.015
negative regulation of endothelial cell migration GO:0010596 1 0.015
determination of bilateral symmetry GO:0009855 204 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
glomerulus development GO:0032835 27 0.015
female sex differentiation GO:0046660 4 0.015
mitotic cell cycle GO:0000278 64 0.015
cardiac cell fate commitment GO:0060911 1 0.015
regulation of cell migration GO:0030334 40 0.015
regulation of bmp signaling pathway GO:0030510 39 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of notch signaling pathway GO:0008593 16 0.015
protein acylation GO:0043543 3 0.015
nephron development GO:0072006 31 0.015
macromolecule modification GO:0043412 111 0.015
mechanoreceptor differentiation GO:0042490 37 0.015
regulation of tube size GO:0035150 2 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
telencephalon development GO:0021537 14 0.014
multi organism process GO:0051704 134 0.014
tube formation GO:0035148 25 0.014
negative regulation of chemotaxis GO:0050922 4 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.014
mitotic cell cycle process GO:1903047 48 0.014
muscle tissue development GO:0060537 110 0.014
negative regulation of cell migration GO:0030336 17 0.014
single organism cell adhesion GO:0098602 29 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
response to growth factor GO:0070848 39 0.014
establishment of localization in cell GO:0051649 77 0.014
cell fate specification GO:0001708 68 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
regulation of neurogenesis GO:0050767 87 0.013
nuclear transport GO:0051169 4 0.013
lipid homeostasis GO:0055088 3 0.013
embryonic eye morphogenesis GO:0048048 30 0.013
regulation of cellular component movement GO:0051270 55 0.013
epithelial tube formation GO:0072175 19 0.013
blood circulation GO:0008015 87 0.013
cell part morphogenesis GO:0032990 246 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
tissue remodeling GO:0048771 4 0.013
neural tube patterning GO:0021532 33 0.013
negative regulation of molecular function GO:0044092 23 0.013
adult behavior GO:0030534 2 0.013
muscle cell development GO:0055001 115 0.013
smoothened signaling pathway GO:0007224 30 0.013
pectoral fin development GO:0033339 50 0.013
negative regulation of notch signaling pathway GO:0045746 6 0.013
patterning of blood vessels GO:0001569 15 0.013
compound eye development GO:0048749 2 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
positive regulation of cell differentiation GO:0045597 30 0.013
specification of axis polarity GO:0065001 4 0.013
positive regulation of cell activation GO:0050867 1 0.012
cardiac cell development GO:0055006 21 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.012
regulation of ph GO:0006885 3 0.012
regulation of extent of cell growth GO:0061387 29 0.012
positive regulation of leukocyte migration GO:0002687 2 0.012
intracellular transport GO:0046907 32 0.012
positive regulation of cell motility GO:2000147 11 0.012
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.012
skeletal muscle organ development GO:0060538 78 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
regulation of response to stress GO:0080134 36 0.012
endothelium development GO:0003158 25 0.011
peptide transport GO:0015833 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regionalization GO:0003002 274 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of angiogenesis GO:0045765 26 0.011
exocrine system development GO:0035272 28 0.011
cellular hormone metabolic process GO:0034754 19 0.011
embryonic heart tube development GO:0035050 133 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
endothelial cell migration GO:0043542 19 0.011
renal tubule development GO:0061326 5 0.011
endocytosis GO:0006897 16 0.011
regulation of protein metabolic process GO:0051246 56 0.011
negative regulation of protein transport GO:0051224 3 0.011
regulation of response to external stimulus GO:0032101 31 0.011
regulation of neutrophil migration GO:1902622 6 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
extracellular matrix organization GO:0030198 27 0.011
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.011
regulation of neutrophil chemotaxis GO:0090022 5 0.011
neural crest cell development GO:0014032 62 0.011
regulation of binding GO:0051098 3 0.011
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
cellular protein metabolic process GO:0044267 129 0.011
segment polarity determination GO:0007367 1 0.011

plekhg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
cardiovascular system disease DOID:1287 0 0.022
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.020
nervous system disease DOID:863 0 0.014