Danio rerio

0 known processes

map2k2a

mitogen-activated protein kinase kinase 2a

(Aliases: map2k2,wu:fa56c06,zgc:123171,MGC123171)

map2k2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.365
Worm
localization of cell GO:0051674 244 0.193
Mouse Fly
positive regulation of cell cycle GO:0045787 3 0.190
regionalization GO:0003002 274 0.184
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.161
Worm
locomotion GO:0040011 313 0.160
Mouse Fly
aging GO:0007568 2 0.155
Worm
signal transduction GO:0007165 455 0.140
Human Yeast Rat Worm Fly
single organism localization GO:1902578 225 0.133
Yeast
cellular component movement GO:0006928 335 0.129
Mouse Fly
regulation of biological quality GO:0065008 263 0.111
transport GO:0006810 220 0.107
Yeast
establishment of localization GO:0051234 244 0.106
Yeast
cell migration GO:0016477 237 0.093
Fly
cellular macromolecule metabolic process GO:0044260 391 0.092
Human Yeast Rat Worm
immune system process GO:0002376 241 0.091
Fly
positive regulation of biological process GO:0048518 253 0.088
Human Yeast Mouse Rat Worm Fly
response to external stimulus GO:0009605 264 0.087
stem cell division GO:0017145 1 0.087
cellular component assembly GO:0022607 170 0.086
anterior posterior pattern specification GO:0009952 152 0.085
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.081
organelle fusion GO:0048284 3 0.080
positive regulation of cellular process GO:0048522 201 0.080
Human Yeast Mouse Rat Worm Fly
negative regulation of nuclear division GO:0051784 3 0.079
cell motility GO:0048870 244 0.079
Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.079
regulation of synaptic plasticity GO:0048167 1 0.079
neuron differentiation GO:0030182 353 0.078
synaptic growth at neuromuscular junction GO:0051124 2 0.077
nitrogen compound metabolic process GO:0006807 319 0.076
regulation of metabolic process GO:0019222 359 0.075
Human Yeast Rat Worm Fly
guanosine containing compound metabolic process GO:1901068 4 0.072
regulation of establishment of protein localization GO:0070201 4 0.072
heterocycle metabolic process GO:0046483 290 0.071
cell surface receptor signaling pathway GO:0007166 325 0.071
Yeast
stem cell maintenance GO:0019827 4 0.071
nuclear transport GO:0051169 4 0.070
Yeast
positive regulation of cellular component biogenesis GO:0044089 3 0.070
stem cell proliferation GO:0072089 4 0.069
cytoskeleton dependent cytokinesis GO:0061640 3 0.069
regulation of synapse organization GO:0050807 3 0.068
blood vessel development GO:0001568 246 0.066
sensory organ development GO:0007423 393 0.064
single organism transport GO:0044765 206 0.064
Yeast
regulation of synapse assembly GO:0051963 3 0.063
pole plasm assembly GO:0007315 4 0.063
multicellular organism growth GO:0035264 4 0.062
digestive system development GO:0055123 289 0.061
cortical actin cytoskeleton organization GO:0030866 1 0.060
vasculature development GO:0001944 278 0.060
organelle organization GO:0006996 227 0.060
Yeast
single organism organelle organization GO:1902589 199 0.059
Yeast
death GO:0016265 121 0.059
Worm
cellular component morphogenesis GO:0032989 336 0.058
cell morphogenesis involved in differentiation GO:0000904 195 0.058
compound eye development GO:0048749 2 0.056
cytokinesis GO:0000910 3 0.056
maternal determination of anterior posterior axis embryo GO:0008358 4 0.056
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.054
regulation of reproductive process GO:2000241 4 0.054
Yeast
generation of neurons GO:0048699 385 0.054
meiotic nuclear division GO:0007126 4 0.054
single organism metabolic process GO:0044710 217 0.054
Human Yeast Rat Worm Fly
positive regulation of transport GO:0051050 2 0.054
tube morphogenesis GO:0035239 349 0.053
positive regulation of apoptotic signaling pathway GO:2001235 1 0.052
negative regulation of mitosis GO:0045839 3 0.052
regulation of protein complex assembly GO:0043254 3 0.052
oocyte anterior posterior axis specification GO:0007314 4 0.052
organonitrogen compound metabolic process GO:1901564 74 0.052
membrane fusion GO:0061025 2 0.052
regulation of stem cell proliferation GO:0072091 2 0.051
regulation of multicellular organismal process GO:0051239 277 0.051
negative regulation of biological process GO:0048519 304 0.051
cell projection organization GO:0030030 284 0.051
extrinsic apoptotic signaling pathway GO:0097191 3 0.051
biosynthetic process GO:0009058 294 0.049
positive regulation of protein complex assembly GO:0031334 2 0.049
protein targeting to nucleus GO:0044744 3 0.049
Yeast
guanosine containing compound catabolic process GO:1901069 2 0.049
segmentation GO:0035282 97 0.048
Fly
phagocytosis GO:0006909 3 0.048
protein localization to nucleus GO:0034504 3 0.048
Yeast
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.048
cell projection morphogenesis GO:0048858 244 0.048
adherens junction organization GO:0034332 4 0.047
digestive tract development GO:0048565 265 0.047
regulation of oocyte development GO:0060281 3 0.046
cortical cytoskeleton organization GO:0030865 1 0.045
cell fate commitment GO:0045165 99 0.045
germ line stem cell maintenance GO:0030718 2 0.045
blood vessel morphogenesis GO:0048514 216 0.045
nucleocytoplasmic transport GO:0006913 4 0.044
Yeast
negative regulation of protein phosphorylation GO:0001933 4 0.044
regulation of protein transport GO:0051223 3 0.044
regulation of localization GO:0032879 104 0.044
Mouse
chordate embryonic development GO:0043009 271 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.043
negative regulation of protein kinase activity GO:0006469 4 0.043
regulation of developmental process GO:0050793 247 0.043
cell morphogenesis GO:0000902 289 0.043
cytoskeleton organization GO:0007010 96 0.042
Yeast
modification dependent macromolecule catabolic process GO:0043632 3 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.042
purine nucleoside monophosphate catabolic process GO:0009128 4 0.042
cell death GO:0008219 121 0.042
Worm
cellular protein metabolic process GO:0044267 129 0.042
Human Yeast Rat Worm
regulation of signal transduction GO:0009966 225 0.042
Human Yeast Rat Worm Fly
regulation of multicellular organism growth GO:0040014 4 0.041
gastrulation GO:0007369 208 0.041
regulation of cellular amine metabolic process GO:0033238 0 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
protein dephosphorylation GO:0006470 3 0.041
protein import into nucleus GO:0006606 3 0.041
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.041
negative regulation of synapse assembly GO:0051964 2 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
amine metabolic process GO:0009308 2 0.040
gtp catabolic process GO:0006184 2 0.040
ameboidal type cell migration GO:0001667 143 0.039
Fly
proteasomal protein catabolic process GO:0010498 2 0.039
protein metabolic process GO:0019538 183 0.039
Human Yeast Rat Worm
regulation of cellular component organization GO:0051128 86 0.039
Yeast
cellular component biogenesis GO:0044085 178 0.039
maintenance of location GO:0051235 4 0.038
regulation of cell death GO:0010941 103 0.038
single organism membrane fusion GO:0044801 2 0.038
negative regulation of kinase activity GO:0033673 4 0.038
cellular amine metabolic process GO:0044106 2 0.038
organic substance biosynthetic process GO:1901576 289 0.038
regulation of intracellular protein transport GO:0033157 3 0.037
neuron development GO:0048666 262 0.037
eye development GO:0001654 277 0.037
cellular ketone metabolic process GO:0042180 11 0.037
cytoplasm organization GO:0007028 4 0.037
endosomal transport GO:0016197 2 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
Yeast
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.037
response to chemical GO:0042221 320 0.037
Yeast
organic acid metabolic process GO:0006082 31 0.036
erk1 and erk2 cascade GO:0070371 4 0.036
Fly
centrosome duplication GO:0051298 1 0.036
digestive tract morphogenesis GO:0048546 231 0.036
regulation of metal ion transport GO:0010959 4 0.036
exocytosis GO:0006887 1 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.035
regulation of neural precursor cell proliferation GO:2000177 3 0.035
cellular protein catabolic process GO:0044257 4 0.035
cellular carbohydrate metabolic process GO:0044262 4 0.035
regulation of cell development GO:0060284 100 0.035
peptidyl serine phosphorylation GO:0018105 1 0.035
Human
regulation of cytoplasmic transport GO:1903649 4 0.034
meiotic cell cycle process GO:1903046 3 0.034
angiogenesis GO:0001525 158 0.034
regulation of cell communication GO:0010646 232 0.034
Human Yeast Rat Worm Fly
negative regulation of cellular process GO:0048523 283 0.034
apoptotic process GO:0006915 116 0.034
Worm
modification dependent protein catabolic process GO:0019941 3 0.034
regulation of catalytic activity GO:0050790 55 0.034
Human Yeast Rat Worm
muscle structure development GO:0061061 196 0.034
neuroblast proliferation GO:0007405 2 0.034
synaptic vesicle transport GO:0048489 1 0.034
regulation of locomotion GO:0040012 55 0.033
Mouse
nucleic acid metabolic process GO:0090304 244 0.033
establishment of protein localization to plasma membrane GO:0090002 1 0.033
convergent extension GO:0060026 118 0.033
ribonucleoside monophosphate catabolic process GO:0009158 4 0.033
atp catabolic process GO:0006200 4 0.033
cognition GO:0050890 1 0.033
cellular amide metabolic process GO:0043603 4 0.032
positive regulation of catabolic process GO:0009896 4 0.032
multi organism process GO:0051704 134 0.032
Yeast Fly
regulation of primary metabolic process GO:0080090 311 0.032
Human Yeast Rat Worm
regulation of multicellular organismal development GO:2000026 223 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
single organism nuclear import GO:1902593 3 0.031
Yeast
gtp metabolic process GO:0046039 4 0.031
establishment or maintenance of cell polarity GO:0007163 29 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.031
Human Yeast Rat Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
transmembrane transport GO:0055085 120 0.031
regulation of cellular metabolic process GO:0031323 320 0.031
Human Yeast Rat Worm Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.030
oxoacid metabolic process GO:0043436 31 0.030
phosphorus metabolic process GO:0006793 109 0.030
Human Yeast Rat Worm Fly
protein import GO:0017038 3 0.030
Yeast
carboxylic acid metabolic process GO:0019752 22 0.030
nucleoside monophosphate catabolic process GO:0009125 4 0.030
regulation of epithelial cell proliferation GO:0050678 3 0.030
response to external biotic stimulus GO:0043207 97 0.030
regulation of cell size GO:0008361 29 0.030
signal transduction in absence of ligand GO:0038034 1 0.029
small molecule metabolic process GO:0044281 77 0.029
heterocycle biosynthetic process GO:0018130 215 0.029
mitochondrion organization GO:0007005 4 0.029
axonogenesis GO:0007409 152 0.029
regulation of biosynthetic process GO:0009889 250 0.029
intracellular mrna localization GO:0008298 1 0.029
gene expression GO:0010467 252 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
cell part morphogenesis GO:0032990 246 0.029
cellular biosynthetic process GO:0044249 286 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
antimicrobial humoral response GO:0019730 2 0.029
establishment of synaptic vesicle localization GO:0097480 1 0.029
nuclear import GO:0051170 3 0.028
Yeast
regulation of protein catabolic process GO:0042176 1 0.028
cell substrate adhesion GO:0031589 4 0.028
organelle assembly GO:0070925 110 0.028
cellular protein modification process GO:0006464 100 0.028
Human Yeast Rat Worm
heart development GO:0007507 313 0.028
regulation of response to stimulus GO:0048583 269 0.028
Human Yeast Rat Worm Fly
neuromuscular synaptic transmission GO:0007274 2 0.028
regulation of mrna processing GO:0050684 3 0.028
golgi vesicle transport GO:0048193 3 0.028
neurotransmitter transport GO:0006836 2 0.027
negative regulation of catabolic process GO:0009895 3 0.027
regulation of cell differentiation GO:0045595 142 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
adult behavior GO:0030534 2 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
mitotic cell cycle GO:0000278 64 0.027
regulation of neurogenesis GO:0050767 87 0.026
immune system development GO:0002520 191 0.026
microtubule based process GO:0007017 60 0.026
protein localization to plasma membrane GO:0072659 1 0.026
dicarboxylic acid transport GO:0006835 1 0.026
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.026
gland development GO:0048732 143 0.026
positive regulation of apoptotic process GO:0043065 29 0.026
protein stabilization GO:0050821 2 0.026
negative regulation of chromosome organization GO:2001251 1 0.026
neuron projection morphogenesis GO:0048812 161 0.026
synaptic vesicle localization GO:0097479 1 0.025
response to biotic stimulus GO:0009607 97 0.025
response to other organism GO:0051707 97 0.025
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.025
rna localization GO:0006403 4 0.025
neuron neuron synaptic transmission GO:0007270 1 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
g2 dna damage checkpoint GO:0031572 3 0.025
regulation of signaling GO:0023051 235 0.025
Human Yeast Rat Worm Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.025
rna metabolic process GO:0016070 219 0.025
axis specification GO:0009798 43 0.025
Fly
intracellular signal transduction GO:0035556 85 0.025
Human Yeast Rat Worm Fly
anterior posterior axis specification GO:0009948 20 0.024
Fly
mitotic cell cycle process GO:1903047 48 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
regulation of apoptotic process GO:0042981 98 0.024
response to stress GO:0006950 263 0.024
Yeast
positive regulation of cellular catabolic process GO:0031331 3 0.024
lipid storage GO:0019915 1 0.024
single fertilization GO:0007338 3 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
lateral inhibition GO:0046331 1 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
Human Yeast Rat Worm Fly
response to nutrient GO:0007584 3 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
regulation of mrna splicing via spliceosome GO:0048024 3 0.023
negative regulation of neural precursor cell proliferation GO:2000178 1 0.023
negative regulation of metabolic process GO:0009892 86 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
response to topologically incorrect protein GO:0035966 2 0.022
embryonic pattern specification GO:0009880 44 0.022
Fly
regulation of receptor mediated endocytosis GO:0048259 4 0.022
oocyte construction GO:0007308 5 0.022
positive regulation of cell division GO:0051781 2 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
protein modification process GO:0036211 100 0.022
Human Yeast Rat Worm
regulation of chromosome segregation GO:0051983 1 0.022
regulation of cytokine production GO:0001817 3 0.022
negative regulation of developmental process GO:0051093 65 0.022
cell proliferation GO:0008283 80 0.022
centrosome cycle GO:0007098 1 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.022
stem cell differentiation GO:0048863 117 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
peptidyl serine modification GO:0018209 2 0.021
Human
protein polymerization GO:0051258 4 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
muscle cell differentiation GO:0042692 139 0.021
chemotaxis GO:0006935 104 0.021
vesicle mediated transport GO:0016192 22 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
protein heterooligomerization GO:0051291 1 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
Human Yeast Rat Worm
cellular modified amino acid metabolic process GO:0006575 3 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
mononuclear cell proliferation GO:0032943 1 0.021
ion transport GO:0006811 114 0.021
chemosensory behavior GO:0007635 1 0.020
peptide metabolic process GO:0006518 1 0.020
regulation of receptor activity GO:0010469 2 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
regulation of molecular function GO:0065009 70 0.020
Human Yeast Rat Worm
macromolecule biosynthetic process GO:0009059 227 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
regulation of protein metabolic process GO:0051246 56 0.020
Human Yeast Rat Worm
organelle localization GO:0051640 49 0.020
membrane invagination GO:0010324 1 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of binding GO:0051098 3 0.020
stem cell development GO:0048864 82 0.020
fertilization GO:0009566 3 0.020
phagocytosis engulfment GO:0006911 1 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
response to unfolded protein GO:0006986 2 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
glucose homeostasis GO:0042593 1 0.020
axon development GO:0061564 166 0.020
organism emergence from protective structure GO:0071684 4 0.019
hormone transport GO:0009914 2 0.019
hormone secretion GO:0046879 2 0.019
spermatid differentiation GO:0048515 2 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
Fly
cellular response to external stimulus GO:0071496 2 0.019
neurotransmitter secretion GO:0007269 2 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
regulation of anatomical structure size GO:0090066 33 0.019
cytokinetic process GO:0032506 2 0.019
rna 3 end processing GO:0031123 2 0.019
cellular respiration GO:0045333 3 0.019
apoptotic process involved in development GO:1902742 2 0.019
positive regulation of cell death GO:0010942 29 0.019
pigment granule localization GO:0051875 25 0.018
germ line stem cell division GO:0042078 1 0.018
peptide transport GO:0015833 1 0.018
homeostatic process GO:0042592 142 0.018
regulation of dendrite development GO:0050773 3 0.018
somitogenesis GO:0001756 87 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
spermatid development GO:0007286 2 0.018
regulation of cellular protein catabolic process GO:1903362 1 0.018
striated muscle cell differentiation GO:0051146 129 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.018
single organism biosynthetic process GO:0044711 71 0.018
homeostasis of number of cells GO:0048872 62 0.018
regulation of protein binding GO:0043393 3 0.018
centrosome organization GO:0051297 1 0.018
meiotic chromosome segregation GO:0045132 3 0.018
actin cytoskeleton organization GO:0030036 63 0.018
Yeast
positive regulation of stress activated mapk cascade GO:0032874 3 0.018
regulation of cell shape GO:0008360 1 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
er nucleus signaling pathway GO:0006984 2 0.018
regulation of cellular component movement GO:0051270 55 0.018
Mouse
regulation of cell substrate adhesion GO:0010810 1 0.017
post golgi vesicle mediated transport GO:0006892 1 0.017
regulation of autophagy GO:0010506 3 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
regulation of glucose import GO:0046324 1 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
pyruvate metabolic process GO:0006090 1 0.017
female meiotic division GO:0007143 2 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
phosphorylation GO:0016310 69 0.017
Human Yeast Rat Worm Fly
carbohydrate homeostasis GO:0033500 1 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
Yeast
developmental growth GO:0048589 166 0.017
mitotic g2 m transition checkpoint GO:0044818 3 0.017
nuclear export GO:0051168 1 0.017
cellular macromolecule localization GO:0070727 21 0.017
Yeast
regulation of cell maturation GO:1903429 1 0.017
membrane organization GO:0061024 21 0.017
regulation of cell motility GO:2000145 46 0.017
Mouse
hatching GO:0035188 4 0.017
head development GO:0060322 303 0.017
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
regulation of protein targeting GO:1903533 2 0.017
negative regulation of reproductive process GO:2000242 3 0.017
ion transmembrane transport GO:0034220 91 0.017
central nervous system development GO:0007417 387 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
oocyte development GO:0048599 14 0.016
regulation of gene expression GO:0010468 265 0.016
cellular localization GO:0051641 97 0.016
Yeast
carbohydrate biosynthetic process GO:0016051 1 0.016
actin filament polymerization GO:0030041 2 0.016
lymphocyte proliferation GO:0046651 1 0.016
response to organic substance GO:0010033 153 0.016
Yeast
neuron projection development GO:0031175 180 0.016
regulation of extent of cell growth GO:0061387 29 0.016
immune response GO:0006955 28 0.016
negative regulation of cell cycle GO:0045786 14 0.016
dicarboxylic acid metabolic process GO:0043648 1 0.016
endoplasmic reticulum unfolded protein response GO:0030968 2 0.016
skeletal system development GO:0001501 181 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
Worm Fly
muscle cell development GO:0055001 115 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Human Yeast Rat Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
primary neural tube formation GO:0014020 1 0.016
regulation of wound healing GO:0061041 2 0.016
nucleic acid templated transcription GO:0097659 181 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
cellular transition metal ion homeostasis GO:0046916 3 0.016
adherens junction maintenance GO:0034334 2 0.016
positive regulation of jnk cascade GO:0046330 3 0.016
regulation of calcium ion transport GO:0051924 2 0.016
nucleobase containing small molecule metabolic process GO:0055086 32 0.016
spindle assembly GO:0051225 2 0.016
regulation of skeletal muscle tissue development GO:0048641 4 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
response to uv GO:0009411 3 0.016
cellular component maintenance GO:0043954 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of protein localization to plasma membrane GO:1903076 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
secondary metabolic process GO:0019748 3 0.015
myeloid cell homeostasis GO:0002262 56 0.015
mitochondrial transport GO:0006839 2 0.015
regulation of protein polymerization GO:0032271 2 0.015
synaptic vesicle recycling GO:0036465 1 0.015
liver development GO:0001889 96 0.015
ras protein signal transduction GO:0007265 7 0.015
Worm Fly
response to carbohydrate GO:0009743 3 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
Human Yeast Rat Worm
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
negative regulation of signaling GO:0023057 96 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
cellular response to oxygen levels GO:0071453 1 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
synaptic vesicle endocytosis GO:0048488 1 0.015
female sex differentiation GO:0046660 4 0.015
embryonic skeletal system development GO:0048706 97 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of transporter activity GO:0032409 2 0.015
glial cell migration GO:0008347 3 0.015
macromolecule localization GO:0033036 54 0.015
Yeast
regulation of cell cycle GO:0051726 52 0.015
establishment of localization in cell GO:0051649 77 0.015
Yeast
regulation of axonogenesis GO:0050770 32 0.015
cell matrix adhesion GO:0007160 4 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
embryonic axis specification GO:0000578 12 0.015
Fly
mitotic cytokinesis GO:0000281 3 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
cellular component disassembly GO:0022411 1 0.015
somite development GO:0061053 96 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
cellular response to organic substance GO:0071310 105 0.015
Yeast
protein homooligomerization GO:0051260 3 0.014
transcription dna templated GO:0006351 181 0.014
regulation of nervous system development GO:0051960 90 0.014
negative regulation of cellular component organization GO:0051129 16 0.014
negative regulation of gene expression GO:0010629 65 0.014
response to monosaccharide GO:0034284 3 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
positive regulation of translation GO:0045727 1 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
Human Yeast Rat Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
positive regulation of reproductive process GO:2000243 2 0.014
Yeast
negative regulation of protein transport GO:0051224 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
amino acid transport GO:0006865 2 0.014
protein acylation GO:0043543 3 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
Human Yeast Rat Worm Fly
negative regulation of defense response GO:0031348 2 0.014
brain development GO:0007420 293 0.014
hemopoiesis GO:0030097 183 0.014
regulation of translational initiation GO:0006446 1 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
regulation of exocytosis GO:0017157 1 0.014
carbohydrate derivative biosynthetic process GO:1901137 43 0.014

map2k2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.033
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.017
musculoskeletal system disease DOID:17 0 0.015