Danio rerio

145 known processes

fgfr1a

fibroblast growth factor receptor 1a

(Aliases: cb231,sb:cb231,fgfr1)

fgfr1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.993
Mouse
chemotaxis GO:0006935 104 0.990
Worm
gastrulation GO:0007369 208 0.986
regulation of gene expression GO:0010468 265 0.983
Mouse Rat
response to external stimulus GO:0009605 264 0.981
Worm Fly
regulation of developmental process GO:0050793 247 0.977
taxis GO:0042330 109 0.974
Worm
response to chemical GO:0042221 320 0.973
cellular component morphogenesis GO:0032989 336 0.967
Zebrafish Worm Fly
axon guidance GO:0007411 86 0.964
Worm
macromolecule biosynthetic process GO:0009059 227 0.957
Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.956
digestive tract morphogenesis GO:0048546 231 0.955
cell morphogenesis involved in differentiation GO:0000904 195 0.954
Worm Fly
ear morphogenesis GO:0042471 64 0.944
Mouse
regulation of cell death GO:0010941 103 0.943
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.943
Human Mouse Rat Fly
cellular biosynthetic process GO:0044249 286 0.937
Mouse Rat
embryonic organ development GO:0048568 381 0.923
Mouse
regulation of multicellular organismal process GO:0051239 277 0.915
response to abiotic stimulus GO:0009628 122 0.912
regulation of cellular metabolic process GO:0031323 320 0.906
Human Mouse Rat Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.902
regulation of cell morphogenesis GO:0022604 42 0.900
Fly
regulation of organ growth GO:0046620 3 0.897
Mouse
organelle organization GO:0006996 227 0.891
Zebrafish
central nervous system development GO:0007417 387 0.883
Zebrafish Mouse Rat Fly
regulation of cell shape GO:0008360 1 0.877
Fly
eye development GO:0001654 277 0.869
cell migration involved in gastrulation GO:0042074 79 0.866
Fly
positive regulation of cell cycle GO:0045787 3 0.858
Mouse
digestive tract development GO:0048565 265 0.857
ameboidal type cell migration GO:0001667 143 0.857
Fly
mesoderm formation GO:0001707 43 0.847
Mouse Fly
inner ear development GO:0048839 126 0.836
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.827
Mouse Rat
stem cell differentiation GO:0048863 117 0.823
Mouse Rat Fly
transcription dna templated GO:0006351 181 0.818
Mouse Rat
cellular aromatic compound metabolic process GO:0006725 295 0.806
Mouse Rat
regulation of cell fate specification GO:0042659 20 0.795
head development GO:0060322 303 0.794
Zebrafish Mouse Rat
tissue regeneration GO:0042246 74 0.792
mesodermal cell migration GO:0008078 12 0.790
Fly
programmed cell death GO:0012501 119 0.783
Mouse
death GO:0016265 121 0.783
Mouse
neuron projection development GO:0031175 180 0.780
Mouse Rat Worm Fly
regulation of mesodermal cell fate specification GO:0042661 9 0.779
Mouse
kidney development GO:0001822 92 0.779
Mouse
posterior lateral line system development GO:0048915 46 0.777
dorsal ventral pattern formation GO:0009953 125 0.774
cell projection organization GO:0030030 284 0.773
Zebrafish Mouse Rat Worm Fly
hindbrain development GO:0030902 91 0.759
aging GO:0007568 2 0.758
regulation of organ morphogenesis GO:2000027 35 0.758
Mouse
bmp signaling pathway GO:0030509 52 0.744
digestive system development GO:0055123 289 0.743
neuron projection guidance GO:0097485 86 0.738
Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.736
positive regulation of multicellular organismal process GO:0051240 52 0.726
Human Mouse Rat
developmental growth GO:0048589 166 0.726
response to stress GO:0006950 263 0.725
regulation of cellular biosynthetic process GO:0031326 245 0.724
Mouse Rat
striated muscle cell development GO:0055002 108 0.717
Fly
epidermis development GO:0008544 48 0.705
Mouse
apoptotic process GO:0006915 116 0.702
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.702
Mouse Rat
establishment of localization GO:0051234 244 0.701
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.692
Mouse Rat
positive regulation of biological process GO:0048518 253 0.689
Human Mouse Rat Fly
regulation of cell growth GO:0001558 29 0.684
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.668
Mouse Rat
locomotory behavior GO:0007626 34 0.654
sensory perception GO:0007600 39 0.652
Mouse Rat
regulation of cell communication GO:0010646 232 0.644
Human Mouse Fly
regulation of apoptotic process GO:0042981 98 0.635
Mouse
sensory organ morphogenesis GO:0090596 200 0.619
Mouse
mechanoreceptor differentiation GO:0042490 37 0.612
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.602
Mouse Rat
morphogenesis of an epithelium GO:0002009 333 0.601
reproductive process GO:0022414 40 0.592
Worm Fly
response to wounding GO:0009611 116 0.590
neuron projection morphogenesis GO:0048812 161 0.580
Worm Fly
developmental growth involved in morphogenesis GO:0060560 86 0.578
Fly
regulation of axon extension GO:0030516 24 0.577
Fly
regulation of axonogenesis GO:0050770 32 0.576
Fly
single organism organelle organization GO:1902589 199 0.575
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.574
Mouse Rat
neuron differentiation GO:0030182 353 0.571
Human Mouse Rat Worm Fly
regulation of endodermal cell fate specification GO:0042663 15 0.571
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.561
Worm Fly
forebrain neuron development GO:0021884 7 0.561
Rat
inner ear morphogenesis GO:0042472 63 0.557
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.552
Mouse Rat
anterior posterior pattern specification GO:0009952 152 0.541
regeneration GO:0031099 91 0.540
regulation of metabolic process GO:0019222 359 0.538
Human Mouse Rat Fly
negative regulation of multicellular organismal process GO:0051241 69 0.536
rna metabolic process GO:0016070 219 0.530
Mouse Rat
regionalization GO:0003002 274 0.516
cell migration GO:0016477 237 0.515
Rat Worm Fly
regulation of heart growth GO:0060420 2 0.514
Mouse
hair cell differentiation GO:0035315 32 0.510
Mouse
regulation of response to stimulus GO:0048583 269 0.509
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.507
Mouse Rat
rna biosynthetic process GO:0032774 181 0.500
Mouse Rat
neuron development GO:0048666 262 0.495
Mouse Rat Worm Fly
axon development GO:0061564 166 0.494
Worm Fly
larval development GO:0002164 2 0.494
Worm Fly
signal transduction GO:0007165 455 0.486
regulation of cell division GO:0051302 12 0.484
cell death GO:0008219 121 0.483
Mouse
formation of primary germ layer GO:0001704 62 0.482
diencephalon development GO:0021536 58 0.481
reproduction GO:0000003 40 0.479
Worm Fly
cartilage development GO:0051216 96 0.476
Mouse
retina development in camera type eye GO:0060041 146 0.475
endodermal cell fate determination GO:0007493 2 0.474
Fly
mesoderm development GO:0007498 88 0.474
Zebrafish Mouse Fly
axon extension GO:0048675 45 0.468
Fly
mesoderm morphogenesis GO:0048332 51 0.466
Mouse Fly
negative regulation of biological process GO:0048519 304 0.464
negative regulation of programmed cell death GO:0043069 58 0.463
mesodermal cell differentiation GO:0048333 21 0.461
Mouse Fly
maintenance of location GO:0051235 4 0.451
embryonic organ morphogenesis GO:0048562 274 0.450
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.443
Mouse
regulation of signal transduction GO:0009966 225 0.434
Human Mouse Fly
cellular response to growth factor stimulus GO:0071363 39 0.433
tube morphogenesis GO:0035239 349 0.421
cardiocyte differentiation GO:0035051 44 0.421
Fly
cell fate commitment GO:0045165 99 0.415
organelle fission GO:0048285 23 0.411
apoptotic signaling pathway GO:0097190 23 0.409
Mouse
hemopoiesis GO:0030097 183 0.407
stem cell proliferation GO:0072089 4 0.403
Mouse Rat
regulation of programmed cell death GO:0043067 101 0.402
Mouse
gland development GO:0048732 143 0.400
cellular component movement GO:0006928 335 0.395
Rat Worm Fly
system process GO:0003008 185 0.395
Mouse Rat
regulation of endodermal cell differentiation GO:1903224 15 0.390
cell proliferation GO:0008283 80 0.384
Human Zebrafish Mouse Rat
striated muscle tissue development GO:0014706 110 0.383
nucleobase containing compound metabolic process GO:0006139 274 0.383
Mouse Rat
cell motility GO:0048870 244 0.375
Rat Worm Fly
pancreas development GO:0031016 84 0.370
Zebrafish
muscle tissue development GO:0060537 110 0.369
stem cell maintenance GO:0019827 4 0.363
Rat
regulation of wnt signaling pathway GO:0030111 53 0.355
odontogenesis of dentin containing tooth GO:0042475 1 0.351
nucleic acid templated transcription GO:0097659 181 0.348
Mouse Rat
locomotion GO:0040011 313 0.341
Rat Worm Fly
meiotic nuclear division GO:0007126 4 0.341
negative regulation of cellular process GO:0048523 283 0.339
negative regulation of apoptotic process GO:0043066 55 0.339
homeostatic process GO:0042592 142 0.338
regulation of transcription dna templated GO:0006355 213 0.337
Mouse Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.335
Mouse Rat
regulation of system process GO:0044057 40 0.334
Rat
protein metabolic process GO:0019538 183 0.332
negative regulation of cell death GO:0060548 60 0.330
regulation of hydrolase activity GO:0051336 28 0.326
Human
camera type eye development GO:0043010 222 0.326
cell morphogenesis GO:0000902 289 0.321
Zebrafish Worm Fly
cell surface receptor signaling pathway GO:0007166 325 0.318
positive regulation of striated muscle tissue development GO:0045844 1 0.317
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.317
Mouse Rat
regulation of developmental growth GO:0048638 38 0.316
Mouse Fly
wnt signaling pathway GO:0016055 80 0.309
positive regulation of molecular function GO:0044093 33 0.307
Human Fly
regulation of meiotic cell cycle GO:0051445 1 0.306
regulation of cellular component size GO:0032535 30 0.302
Fly
regulation of growth GO:0040008 42 0.301
Mouse Fly
gene expression GO:0010467 252 0.301
Mouse Rat
cell adhesion GO:0007155 40 0.300
cardiac muscle tissue development GO:0048738 48 0.298
heterocycle metabolic process GO:0046483 290 0.294
Mouse Rat
regulation of cell cycle GO:0051726 52 0.293
Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.289
Human Fly
biosynthetic process GO:0009058 294 0.289
Mouse Rat
neuroblast proliferation GO:0007405 2 0.288
Mouse
inner ear receptor cell differentiation GO:0060113 29 0.282
Mouse
regulation of multicellular organismal development GO:2000026 223 0.282
regulation of cell differentiation GO:0045595 142 0.282
growth GO:0040007 174 0.278
brain development GO:0007420 293 0.278
Zebrafish Mouse Rat
regulation of biosynthetic process GO:0009889 250 0.273
Mouse Rat
glial cell differentiation GO:0010001 42 0.272
Fly
specification of symmetry GO:0009799 204 0.271
Zebrafish
response to decreased oxygen levels GO:0036293 25 0.270
positive regulation of cell proliferation GO:0008284 15 0.270
Human Mouse Rat
chordate embryonic development GO:0043009 271 0.269
Mouse
regulation of protein metabolic process GO:0051246 56 0.269
Human Fly
regulation of cardiac muscle tissue development GO:0055024 1 0.268
Mouse
lateral line development GO:0048882 66 0.266
fin regeneration GO:0031101 51 0.265
hepaticobiliary system development GO:0061008 98 0.263
single organism localization GO:1902578 225 0.263
Worm
response to organic substance GO:0010033 153 0.262
appendage morphogenesis GO:0035107 56 0.257
Mouse
establishment of localization in cell GO:0051649 77 0.256
Worm
immune system development GO:0002520 191 0.255
Fly
locus ceruleus development GO:0021703 3 0.253
inner ear receptor cell development GO:0060119 20 0.249
Mouse
cell cycle process GO:0022402 53 0.248
heart development GO:0007507 313 0.245
positive regulation of transcription dna templated GO:0045893 57 0.244
Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.244
Mouse Rat
immune system process GO:0002376 241 0.242
Fly
striated muscle cell differentiation GO:0051146 129 0.236
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.234
Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.233
lateral line system development GO:0048925 76 0.227
aromatic compound biosynthetic process GO:0019438 217 0.223
Mouse Rat
response to growth factor GO:0070848 39 0.222
hematopoietic or lymphoid organ development GO:0048534 191 0.219
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.219
Mouse Rat
regulation of neuron differentiation GO:0045664 56 0.217
Human Mouse Rat Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.214
Mouse Worm
cellular localization GO:0051641 97 0.214
Worm
axonogenesis GO:0007409 152 0.213
Worm Fly
protein localization to nucleus GO:0034504 3 0.212
positive regulation of muscle tissue development GO:1901863 1 0.212
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.210
olfactory lobe development GO:0021988 4 0.205
Rat
anatomical structure homeostasis GO:0060249 36 0.202
single organism transport GO:0044765 206 0.198
Worm
germ cell migration GO:0008354 8 0.198
Fly
positive regulation of developmental process GO:0051094 50 0.198
Human Mouse Rat
cell growth GO:0016049 57 0.198
Fly
skin development GO:0043588 54 0.196
posterior lateral line development GO:0048916 38 0.195
regulation of multicellular organism growth GO:0040014 4 0.192
negative regulation of developmental process GO:0051093 65 0.191
epidermal cell differentiation GO:0009913 36 0.188
Mouse
regulation of stem cell proliferation GO:0072091 2 0.188
Mouse Rat
chemical homeostasis GO:0048878 49 0.188
positive regulation of cellular protein metabolic process GO:0032270 22 0.187
Human Fly
sensory system development GO:0048880 76 0.186
fin development GO:0033333 77 0.185
response to endogenous stimulus GO:0009719 83 0.185
positive regulation of cell death GO:0010942 29 0.180
lipid storage GO:0019915 1 0.177
heterocycle biosynthetic process GO:0018130 215 0.175
Mouse Rat
transport GO:0006810 220 0.175
Worm
negative regulation of cell communication GO:0010648 96 0.173
protein complex assembly GO:0006461 30 0.173
negative regulation of growth GO:0045926 10 0.172
Fly
body morphogenesis GO:0010171 16 0.171
regulation of cell migration GO:0030334 40 0.170
cell part morphogenesis GO:0032990 246 0.170
Zebrafish Worm Fly
nucleic acid metabolic process GO:0090304 244 0.170
Mouse Rat
cellular response to extracellular stimulus GO:0031668 2 0.168
negative regulation of metabolic process GO:0009892 86 0.167
Mouse
cellular component biogenesis GO:0044085 178 0.166
Zebrafish Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.164
Fly
negative regulation of gene expression GO:0010629 65 0.162
Mouse
regulation of primary metabolic process GO:0080090 311 0.160
Human Mouse Rat Fly
nephron tubule morphogenesis GO:0072078 1 0.158
ear development GO:0043583 127 0.157
Mouse
endodermal cell differentiation GO:0035987 19 0.156
regulation of macromolecule biosynthetic process GO:0010556 225 0.154
Mouse Rat
intracellular signal transduction GO:0035556 85 0.153
Human Mouse Fly
stem cell division GO:0017145 1 0.153
Mouse
phagocytosis GO:0006909 3 0.153
Worm
negative regulation of signal transduction GO:0009968 94 0.152
positive regulation of signaling GO:0023056 56 0.152
Human Mouse Fly
oocyte maturation GO:0001556 4 0.151
transcription from rna polymerase ii promoter GO:0006366 80 0.150
Mouse Rat
regulation of biological quality GO:0065008 263 0.148
sensory perception of mechanical stimulus GO:0050954 16 0.146
Mouse
multi organism process GO:0051704 134 0.146
Worm Fly
positive regulation of cellular metabolic process GO:0031325 94 0.146
Human Mouse Rat Fly
regulation of cellular component organization GO:0051128 86 0.144
Mouse Rat Worm Fly
negative regulation of protein phosphorylation GO:0001933 4 0.141
regulation of neuron projection development GO:0010975 40 0.141
Mouse Rat Fly
generation of neurons GO:0048699 385 0.140
Human Mouse Rat Worm Fly
stem cell development GO:0048864 82 0.140
Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.137
Rat
multicellular organism reproduction GO:0032504 35 0.136
Worm Fly
determination of heart left right asymmetry GO:0061371 117 0.135
Zebrafish
liver development GO:0001889 96 0.134
heart looping GO:0001947 94 0.134
developmental programmed cell death GO:0010623 4 0.133
positive regulation of muscle organ development GO:0048636 1 0.132
Mouse
positive regulation of protein metabolic process GO:0051247 23 0.132
Human Fly
small molecule metabolic process GO:0044281 77 0.132
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.131
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.131
Rat
macromolecule localization GO:0033036 54 0.130
regulation of apoptotic signaling pathway GO:2001233 12 0.130
Mouse
endodermal cell fate specification GO:0001714 17 0.129
negative regulation of cellular component organization GO:0051129 16 0.128
Fly
regulation of striated muscle tissue development GO:0016202 6 0.126
Mouse
skeletal muscle tissue development GO:0007519 67 0.122
kupffer s vesicle development GO:0070121 50 0.121
single organism cellular localization GO:1902580 46 0.120
forebrain cell migration GO:0021885 1 0.118
Rat
neuroblast differentiation GO:0014016 1 0.118
somitogenesis GO:0001756 87 0.117
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.117
Mouse
regulation of catalytic activity GO:0050790 55 0.116
Human Fly
canonical wnt signaling pathway GO:0060070 48 0.116
positive regulation of apoptotic process GO:0043065 29 0.115
negative regulation of signaling GO:0023057 96 0.112
regulation of inner ear receptor cell differentiation GO:2000980 1 0.112
myotube differentiation GO:0014902 45 0.112
macromolecule modification GO:0043412 111 0.111
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.111
Fly
neurological system process GO:0050877 62 0.110
Mouse Rat
regulation of molecular function GO:0065009 70 0.110
Human Fly
olfactory bulb development GO:0021772 4 0.110
Rat
nuclear division GO:0000280 23 0.109
adenohypophysis development GO:0021984 15 0.108
regulation of organelle organization GO:0033043 29 0.107
regulation of locomotion GO:0040012 55 0.106
regulation of signaling GO:0023051 235 0.103
Human Mouse Fly
osteoblast differentiation GO:0001649 5 0.103
Rat
gliogenesis GO:0042063 45 0.103
Fly
determination of left right symmetry GO:0007368 179 0.099
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.099
Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 7 0.098
developmental process involved in reproduction GO:0003006 27 0.098
Worm Fly
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.098
positive regulation of programmed cell death GO:0043068 29 0.097
response to hypoxia GO:0001666 25 0.097
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.095
positive regulation of nucleic acid templated transcription GO:1903508 57 0.094
Rat
skeletal system development GO:0001501 181 0.094
Mouse
organic substance transport GO:0071702 58 0.094
cellular amino acid metabolic process GO:0006520 7 0.093
homeostasis of number of cells GO:0048872 62 0.092
convergent extension GO:0060026 118 0.092
astrocyte differentiation GO:0048708 1 0.092
cellular response to decreased oxygen levels GO:0036294 1 0.091
muscle organ development GO:0007517 101 0.089
Mouse Worm Fly
carbohydrate derivative metabolic process GO:1901135 61 0.088
regulation of embryonic development GO:0045995 47 0.088
cognition GO:0050890 1 0.088
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.088
urogenital system development GO:0001655 97 0.086
Mouse Fly
wound healing GO:0042060 90 0.086
positive regulation of biosynthetic process GO:0009891 68 0.086
Rat
pectoral fin development GO:0033339 50 0.086
mechanosensory lateral line system development GO:0048881 49 0.085
hypothalamus cell differentiation GO:0021979 4 0.084
primary neural tube formation GO:0014020 1 0.083
central nervous system neuron development GO:0021954 29 0.082
Rat
convergent extension involved in gastrulation GO:0060027 71 0.082
proteolysis GO:0006508 38 0.082
somatic muscle development GO:0007525 4 0.081
Fly
nephron morphogenesis GO:0072028 2 0.081
positive regulation of map kinase activity GO:0043406 3 0.080
Human Fly
mesenchymal cell differentiation GO:0048762 87 0.080
Mouse
negative regulation of gastrulation GO:2000542 11 0.079
renal system development GO:0072001 94 0.079
Mouse Fly
regulation of cartilage development GO:0061035 7 0.079
regulation of extent of cell growth GO:0061387 29 0.078
Fly
cell cycle GO:0007049 93 0.078
Mouse
epithelial tube morphogenesis GO:0060562 148 0.077
Fly
eye morphogenesis GO:0048592 144 0.077
cellular protein metabolic process GO:0044267 129 0.077
auditory receptor cell differentiation GO:0042491 15 0.075
Mouse
cellular amine metabolic process GO:0044106 2 0.075
striated muscle cell proliferation GO:0014855 7 0.075
Mouse
positive regulation of signal transduction GO:0009967 56 0.075
Human Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.075
Mouse
sensory perception of chemical stimulus GO:0007606 3 0.075
regulation of neurogenesis GO:0050767 87 0.075
Human Mouse Rat Fly
abducens nerve development GO:0021560 1 0.074
regulation of intracellular signal transduction GO:1902531 57 0.074
Human Mouse Fly
negative regulation of response to stimulus GO:0048585 104 0.074
regulation of behavior GO:0050795 24 0.073
phosphorylation GO:0016310 69 0.072
mesodermal cell fate specification GO:0007501 12 0.072
Mouse
multi organism cellular process GO:0044764 2 0.072
actin filament based process GO:0030029 64 0.072
positive regulation of developmental growth GO:0048639 6 0.071
Mouse
glucose homeostasis GO:0042593 1 0.069
cellular ketone metabolic process GO:0042180 11 0.069
regulation of canonical wnt signaling pathway GO:0060828 34 0.069
radial glial cell differentiation GO:0060019 2 0.069
regulation of cell motility GO:2000145 46 0.068
regulation of endopeptidase activity GO:0052548 23 0.068
single organism metabolic process GO:0044710 217 0.067
Human Mouse Fly
cranial suture morphogenesis GO:0060363 1 0.067
skeletal system morphogenesis GO:0048705 102 0.065
apoptotic process involved in morphogenesis GO:0060561 2 0.064
glial cell migration GO:0008347 3 0.063
Fly
forebrain development GO:0030900 96 0.063
Mouse Rat
regulation of neuron migration GO:2001222 2 0.063
response to nutrient GO:0007584 3 0.063
regulation of protein phosphorylation GO:0001932 18 0.062
Human Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.062
endocardial cushion formation GO:0003272 2 0.062
regulation of mesoderm development GO:2000380 11 0.062
Mouse
regulation of chemotaxis GO:0050920 18 0.062
otic vesicle development GO:0071599 42 0.061
response to oxygen containing compound GO:1901700 55 0.061
sensory perception of sound GO:0007605 9 0.060
Mouse
renal tubule morphogenesis GO:0061333 1 0.060
multicellular organismal homeostasis GO:0048871 29 0.060
retinal ganglion cell axon guidance GO:0031290 35 0.059
protein complex subunit organization GO:0071822 46 0.057
carboxylic acid metabolic process GO:0019752 22 0.056
positive regulation of epithelial cell proliferation GO:0050679 1 0.056
negative regulation of intracellular signal transduction GO:1902532 22 0.056
positive regulation of rna metabolic process GO:0051254 59 0.056
Rat
cardioblast differentiation GO:0010002 9 0.055
Fly
regulation of mitotic cell cycle GO:0007346 25 0.055
response to temperature stimulus GO:0009266 15 0.055
regulation of rna metabolic process GO:0051252 224 0.055
Mouse Rat
positive regulation of nervous system development GO:0051962 25 0.054
Human Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.054
actin cytoskeleton organization GO:0030036 63 0.054
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.054
ectodermal placode morphogenesis GO:0071697 32 0.054
muscle cell development GO:0055001 115 0.054
Fly
regulation of anatomical structure size GO:0090066 33 0.053
Fly
neural tube development GO:0021915 62 0.053
otic vesicle morphogenesis GO:0071600 34 0.052
peptidyl tyrosine modification GO:0018212 5 0.052
fin morphogenesis GO:0033334 53 0.052
neuromast development GO:0048884 46 0.052
neural precursor cell proliferation GO:0061351 20 0.051
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.051
Rat
regulation of epithelial cell proliferation GO:0050678 3 0.050
mitotic cell cycle process GO:1903047 48 0.050
cellular component assembly GO:0022607 170 0.050
Zebrafish Fly
pharyngeal muscle development GO:0043282 4 0.049
otic vesicle formation GO:0030916 27 0.049
organ growth GO:0035265 12 0.049
Mouse
protein localization GO:0008104 40 0.049
behavior GO:0007610 74 0.048
Worm
regulation of cellular component movement GO:0051270 55 0.048
regulation of localization GO:0032879 104 0.048
actin filament organization GO:0007015 15 0.048
protein import into nucleus GO:0006606 3 0.047
regulation of circadian rhythm GO:0042752 4 0.047
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.047
Mouse
motor neuron axon guidance GO:0008045 23 0.047
nephron epithelium morphogenesis GO:0072088 1 0.046
specification of organ identity GO:0010092 2 0.046
Mouse
kidney epithelium development GO:0072073 23 0.046
Mouse
cytoskeleton organization GO:0007010 96 0.046
terpenoid catabolic process GO:0016115 2 0.046
heart morphogenesis GO:0003007 156 0.046
determination of bilateral symmetry GO:0009855 204 0.046
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.046
Human Mouse Fly
regulation of peptidase activity GO:0052547 23 0.045
organic acid metabolic process GO:0006082 31 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.045
Rat
diterpenoid catabolic process GO:0016103 2 0.044
cilium morphogenesis GO:0060271 85 0.044
Zebrafish
limbic system development GO:0021761 16 0.044
Mouse
response to mechanical stimulus GO:0009612 24 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.043
synaptic growth at neuromuscular junction GO:0051124 2 0.043
tube closure GO:0060606 1 0.043
pigmentation GO:0043473 85 0.043
positive regulation of cellular catabolic process GO:0031331 3 0.043
oxoacid metabolic process GO:0043436 31 0.042
multicellular organismal reproductive process GO:0048609 35 0.042
Worm Fly
multicellular organism growth GO:0035264 4 0.042
mesodermal cell fate commitment GO:0001710 14 0.042
Mouse Fly
embryonic eye morphogenesis GO:0048048 30 0.042
cell division GO:0051301 20 0.042
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.041
regulation of mechanoreceptor differentiation GO:0045631 1 0.041
female gonad development GO:0008585 4 0.040
mitotic cell cycle GO:0000278 64 0.040
positive regulation of apoptotic signaling pathway GO:2001235 1 0.040

fgfr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.523
Human
reproductive system disease DOID:15 0 0.239
Human
bone disease DOID:0080001 0 0.186
Human
musculoskeletal system disease DOID:17 0 0.186
Human
connective tissue disease DOID:65 0 0.186
Human
bone development disease DOID:0080006 0 0.126
Human
acrocephalosyndactylia DOID:12960 0 0.126
Human
dysostosis DOID:1934 0 0.126
Human
synostosis DOID:11971 0 0.126
Human
pfeiffer syndrome DOID:14705 0 0.097
Human
orofacial cleft DOID:0050567 0 0.073
physical disorder DOID:0080015 0 0.073
osteochondrodysplasia DOID:2256 0 0.067
cleidocranial dysplasia DOID:13994 0 0.067
congenital heart disease DOID:1682 0 0.057
heart septal defect DOID:1681 0 0.057
atrioventricular septal defect DOID:0050651 0 0.057
heart disease DOID:114 0 0.057
cardiovascular system disease DOID:1287 0 0.057
syndrome DOID:225 0 0.053
tooth and nail syndrome DOID:6678 0 0.053
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
denys drash syndrome DOID:3764 0 0.041