Danio rerio

7 known processes

fgfr1b

fibroblast growth factor receptor 1b

(Aliases: si:ch211-180b9.1)

fgfr1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.934
Zebrafish Mouse Fly
sensory organ development GO:0007423 393 0.866
Mouse
chordate embryonic development GO:0043009 271 0.841
Mouse
heterocycle metabolic process GO:0046483 290 0.730
Mouse Rat
anterior posterior pattern specification GO:0009952 152 0.709
morphogenesis of an epithelium GO:0002009 333 0.694
Zebrafish Mouse Fly
signal transduction GO:0007165 455 0.688
Human Zebrafish Mouse Worm Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.684
Mouse Rat
negative regulation of cellular process GO:0048523 283 0.683
Zebrafish Mouse Rat Fly
cell proliferation in forebrain GO:0021846 3 0.633
Mouse
regionalization GO:0003002 274 0.627
Zebrafish Mouse
regulation of multicellular organismal process GO:0051239 277 0.594
Human Zebrafish Mouse Rat Fly
regulation of metabolic process GO:0019222 359 0.567
Human Mouse Rat Fly
eye development GO:0001654 277 0.561
regulation of signal transduction GO:0009966 225 0.559
Human Mouse Fly
neuron projection morphogenesis GO:0048812 161 0.544
Worm Fly
negative regulation of axon extension GO:0030517 7 0.537
Fly
regulation of signaling GO:0023051 235 0.536
Human Mouse Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.527
axonogenesis GO:0007409 152 0.513
Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.508
Human Mouse Rat Fly
response to external stimulus GO:0009605 264 0.508
Worm Fly
sensory organ morphogenesis GO:0090596 200 0.488
Mouse
determination of left right symmetry GO:0007368 179 0.474
Zebrafish
cell proliferation GO:0008283 80 0.463
Human Zebrafish Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.454
Human Zebrafish Mouse Worm
cellular biosynthetic process GO:0044249 286 0.448
Mouse Rat
somite development GO:0061053 96 0.442
embryonic limb morphogenesis GO:0030326 2 0.432
Mouse
muscle structure development GO:0061061 196 0.427
Mouse Worm Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.421
Human Zebrafish Mouse Worm
macromolecule biosynthetic process GO:0009059 227 0.416
Mouse Rat
dorsal ventral pattern formation GO:0009953 125 0.405
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.402
Human Mouse Fly
regulation of response to stimulus GO:0048583 269 0.391
Human Mouse Fly
single organism metabolic process GO:0044710 217 0.381
Human Mouse Fly
positive regulation of cellular process GO:0048522 201 0.371
Human Mouse Rat Fly
bmp signaling pathway GO:0030509 52 0.368
regulation of neuron differentiation GO:0045664 56 0.359
Human Mouse Rat Fly
regulation of multicellular organismal development GO:2000026 223 0.356
Human Zebrafish Mouse Rat Fly
synaptic target recognition GO:0008039 1 0.346
central nervous system development GO:0007417 387 0.341
Zebrafish Mouse Rat Fly
taxis GO:0042330 109 0.335
Worm
kidney development GO:0001822 92 0.327
Mouse
embryonic organ development GO:0048568 381 0.325
Mouse
axon development GO:0061564 166 0.325
Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.313
Worm Fly
immune response GO:0006955 28 0.313
Fly
determination of bilateral symmetry GO:0009855 204 0.308
Zebrafish
formation of anatomical boundary GO:0048859 14 0.307
embryonic heart tube development GO:0035050 133 0.306
blood vessel development GO:0001568 246 0.301
Mouse
specification of symmetry GO:0009799 204 0.300
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.299
Mouse Rat
embryonic camera type eye development GO:0031076 29 0.299
neural tube development GO:0021915 62 0.287
epithelial tube morphogenesis GO:0060562 148 0.284
Fly
cell motility GO:0048870 244 0.284
Rat Worm Fly
cellular component morphogenesis GO:0032989 336 0.272
Zebrafish Worm Fly
response to chemical GO:0042221 320 0.270
Human Zebrafish Mouse Worm
forebrain development GO:0030900 96 0.267
Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.259
Human Zebrafish Mouse Rat Worm Fly
generation of neurons GO:0048699 385 0.257
Human Mouse Rat Worm Fly
organic substance biosynthetic process GO:1901576 289 0.255
Mouse Rat
brain morphogenesis GO:0048854 18 0.246
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.245
Mouse
digestive tract morphogenesis GO:0048546 231 0.242
Zebrafish Mouse Worm Fly
nucleic acid templated transcription GO:0097659 181 0.240
Mouse Rat
chemotaxis GO:0006935 104 0.239
Worm
cell projection morphogenesis GO:0048858 244 0.234
Zebrafish Worm Fly
regulation of cell communication GO:0010646 232 0.225
Human Mouse Fly
transcription dna templated GO:0006351 181 0.221
Mouse Rat
retinal ganglion cell axon guidance GO:0031290 35 0.219
neuron projection extension GO:1990138 45 0.212
Fly
negative regulation of neuron projection regeneration GO:0070571 4 0.205
cellular nitrogen compound biosynthetic process GO:0044271 218 0.204
Mouse Rat
regulation of primary metabolic process GO:0080090 311 0.204
Human Mouse Rat Fly
biosynthetic process GO:0009058 294 0.201
Mouse Rat
cell adhesion GO:0007155 40 0.196
nucleobase containing compound metabolic process GO:0006139 274 0.194
Mouse Rat
tube morphogenesis GO:0035239 349 0.192
Zebrafish Mouse Worm Fly
neural tube patterning GO:0021532 33 0.191
embryonic skeletal system development GO:0048706 97 0.186
neuron differentiation GO:0030182 353 0.181
Human Mouse Rat Worm Fly
skeletal system morphogenesis GO:0048705 102 0.177
phosphorylation GO:0016310 69 0.175
Human Zebrafish Mouse Worm Fly
proximal distal pattern formation GO:0009954 1 0.173
neuron projection development GO:0031175 180 0.165
Mouse Rat Worm Fly
camera type eye development GO:0043010 222 0.162
positive regulation of signaling GO:0023056 56 0.162
Human Mouse Fly
regulation of epithelial cell proliferation GO:0050678 3 0.161
cell part morphogenesis GO:0032990 246 0.156
Zebrafish Worm Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.156
lymphocyte activation GO:0046649 10 0.155
guanosine containing compound metabolic process GO:1901068 4 0.154
axon extension GO:0048675 45 0.148
Fly
somitogenesis GO:0001756 87 0.143
system process GO:0003008 185 0.142
Mouse Rat
protein modification process GO:0036211 100 0.141
Human Zebrafish Mouse Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.139
Mouse Rat
tube formation GO:0035148 25 0.139
positive regulation of biological process GO:0048518 253 0.136
Human Mouse Rat Fly
brain development GO:0007420 293 0.135
Zebrafish Mouse Rat
connective tissue development GO:0061448 99 0.135
Mouse
gene expression GO:0010467 252 0.133
Mouse Rat
embryonic skeletal system morphogenesis GO:0048704 93 0.132
axon guidance GO:0007411 86 0.131
Worm
rostrocaudal neural tube patterning GO:0021903 29 0.129
positive regulation of stress activated mapk cascade GO:0032874 3 0.129
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.128
Mouse Rat
regulation of wnt signaling pathway GO:0030111 53 0.126
cellular response to endogenous stimulus GO:0071495 68 0.125
Human Zebrafish Mouse Worm
regulation of bmp signaling pathway GO:0030510 39 0.123
muscle cell development GO:0055001 115 0.121
Fly
endothelial cell fate commitment GO:0060839 3 0.121
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.121
wnt signaling pathway GO:0016055 80 0.120
neuron development GO:0048666 262 0.120
Mouse Rat Worm Fly
neuron projection guidance GO:0097485 86 0.117
Worm
regulation of anatomical structure morphogenesis GO:0022603 130 0.117
Zebrafish Mouse Fly
phosphorus metabolic process GO:0006793 109 0.116
Human Zebrafish Mouse Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.115
Human Mouse Rat Fly
intracellular signal transduction GO:0035556 85 0.114
Human Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.114
Mouse Rat
embryonic epithelial tube formation GO:0001838 17 0.113
negative regulation of cell differentiation GO:0045596 46 0.112
Zebrafish Rat Fly
regulation of cellular protein metabolic process GO:0032268 52 0.112
Human Fly
neural retina development GO:0003407 49 0.111
rna metabolic process GO:0016070 219 0.111
Mouse Rat
programmed cell death GO:0012501 119 0.111
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.111
Mouse Rat
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.109
nucleic acid metabolic process GO:0090304 244 0.107
Mouse Rat
oocyte maturation GO:0001556 4 0.104
morphogenesis of embryonic epithelium GO:0016331 30 0.104
eye morphogenesis GO:0048592 144 0.104
heterocycle biosynthetic process GO:0018130 215 0.104
Mouse Rat
embryonic cranial skeleton morphogenesis GO:0048701 90 0.101
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.101
regulation of nitrogen compound metabolic process GO:0051171 251 0.100
Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.099
Mouse Rat
regulation of cellular biosynthetic process GO:0031326 245 0.098
Mouse Rat
neural precursor cell proliferation GO:0061351 20 0.096
Zebrafish Mouse
negative chemotaxis GO:0050919 1 0.094
camera type eye morphogenesis GO:0048593 108 0.094
cell morphogenesis GO:0000902 289 0.093
Zebrafish Worm Fly
negative regulation of collateral sprouting GO:0048671 2 0.093
response to stress GO:0006950 263 0.090
Zebrafish Fly
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.089
head development GO:0060322 303 0.089
Zebrafish Mouse Rat
segmentation GO:0035282 97 0.088
liver development GO:0001889 96 0.088
Zebrafish
midbrain development GO:0030901 28 0.088
Zebrafish Mouse
response to biotic stimulus GO:0009607 97 0.087
Fly
negative regulation of biological process GO:0048519 304 0.087
Zebrafish Mouse Rat Fly
skeletal muscle organ development GO:0060538 78 0.087
regulation of response to stress GO:0080134 36 0.087
Fly
regulation of biosynthetic process GO:0009889 250 0.086
Mouse Rat
response to external biotic stimulus GO:0043207 97 0.085
Fly
regulation of cell differentiation GO:0045595 142 0.084
Human Zebrafish Mouse Rat Fly
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.084
angiogenesis GO:0001525 158 0.084
Mouse
positive regulation of lipase activity GO:0060193 1 0.082
Human
skeletal muscle tissue development GO:0007519 67 0.082
erk1 and erk2 cascade GO:0070371 4 0.082
convergent extension GO:0060026 118 0.081
cellular component biogenesis GO:0044085 178 0.080
Zebrafish Fly
single organism cell adhesion GO:0098602 29 0.079
localization of cell GO:0051674 244 0.078
Rat Worm Fly
response to other organism GO:0051707 97 0.077
Fly
mesoderm development GO:0007498 88 0.077
Zebrafish Mouse Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.077
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.077
Mouse Rat
regulation of protein ubiquitination GO:0031396 3 0.076
diencephalon development GO:0021536 58 0.075
positive regulation of cell differentiation GO:0045597 30 0.075
Human Mouse Rat
compound eye development GO:0048749 2 0.074
neuroblast proliferation GO:0007405 2 0.073
Mouse
regulation of axonogenesis GO:0050770 32 0.071
Fly
developmental cell growth GO:0048588 52 0.071
Fly
positive regulation of transcription dna templated GO:0045893 57 0.071
Rat
aromatic compound biosynthetic process GO:0019438 217 0.070
Mouse Rat
cell migration GO:0016477 237 0.070
Rat Worm Fly
gtp metabolic process GO:0046039 4 0.070
canonical wnt signaling pathway GO:0060070 48 0.069
macromolecule modification GO:0043412 111 0.068
Human Zebrafish Mouse Worm Fly
mesenchymal cell differentiation GO:0048762 87 0.068
Mouse
cellular protein metabolic process GO:0044267 129 0.068
Human Zebrafish Mouse Worm Fly
cell projection organization GO:0030030 284 0.067
Zebrafish Mouse Rat Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.067
Mouse Rat
stem cell fate determination GO:0048867 1 0.067
positive regulation of map kinase activity GO:0043406 3 0.066
Human Fly
b cell activation GO:0042113 2 0.066
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.066
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.065
maintenance of location GO:0051235 4 0.065
epithelial cell differentiation GO:0030855 116 0.064
Mouse Fly
positive regulation of muscle organ development GO:0048636 1 0.064
Mouse
regulation of canonical wnt signaling pathway GO:0060828 34 0.064
transcription from rna polymerase ii promoter GO:0006366 80 0.063
Mouse Rat
regulation of gene expression GO:0010468 265 0.063
Mouse Rat
eye photoreceptor cell differentiation GO:0001754 45 0.063
establishment of localization GO:0051234 244 0.062
Worm
digestive system development GO:0055123 289 0.062
Zebrafish Mouse Worm Fly
regulation of muscle organ development GO:0048634 9 0.062
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.061
negative regulation of axon regeneration GO:0048681 4 0.061
regulation of neurological system process GO:0031644 2 0.061
Rat
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.061
cellular response to retinoic acid GO:0071300 1 0.060
protein metabolic process GO:0019538 183 0.060
Human Zebrafish Mouse Worm Fly
phagocytosis GO:0006909 3 0.059
Worm
neuroblast differentiation GO:0014016 1 0.058
regulation of protein catabolic process GO:0042176 1 0.057
negative regulation of neuron projection development GO:0010977 9 0.057
Fly
cellular response to organic substance GO:0071310 105 0.057
Human Zebrafish Mouse Worm
ear morphogenesis GO:0042471 64 0.057
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.056
single organism organelle organization GO:1902589 199 0.056
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.056
Mouse
positive regulation of jnk cascade GO:0046330 3 0.056
gland development GO:0048732 143 0.056
Zebrafish Mouse Fly
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.056
organelle assembly GO:0070925 110 0.056
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.056
Rat
cellular response to lipid GO:0071396 39 0.054
neural tube formation GO:0001841 16 0.054
protein localization to nucleus GO:0034504 3 0.053
embryonic camera type eye formation GO:0060900 10 0.053
muscle cell differentiation GO:0042692 139 0.053
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.053
Mouse Rat
positive regulation of cell cycle GO:0045787 3 0.053
Mouse
cellular protein modification process GO:0006464 100 0.052
Human Zebrafish Mouse Worm Fly
cell surface receptor signaling pathway GO:0007166 325 0.052
Human Zebrafish Mouse Worm
regulation of organ growth GO:0046620 3 0.051
Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.051
branching morphogenesis of a nerve GO:0048755 4 0.051
skeletal system development GO:0001501 181 0.049
Mouse
chondrocyte development GO:0002063 4 0.049
embryo development ending in birth or egg hatching GO:0009792 271 0.048
Mouse Worm
regulation of programmed cell death GO:0043067 101 0.048
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.048
Human Zebrafish Mouse Worm
primary neural tube formation GO:0014020 1 0.047
t cell differentiation in thymus GO:0033077 6 0.047
negative regulation of wnt signaling pathway GO:0030178 30 0.046
regulation of cell death GO:0010941 103 0.046
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.045
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.044
Mouse
response to nutrient GO:0007584 3 0.044
negative regulation of epithelial cell proliferation GO:0050680 1 0.044
glomerulus development GO:0032835 27 0.044
regulation of stem cell proliferation GO:0072091 2 0.043
Mouse Rat
regulation of protein import into nucleus GO:0042306 2 0.043
regulation of erk1 and erk2 cascade GO:0070372 4 0.042
heart looping GO:0001947 94 0.042
negative regulation of axonogenesis GO:0050771 7 0.042
Fly
stem cell maintenance GO:0019827 4 0.042
Rat
protein phosphorylation GO:0006468 47 0.042
Human Zebrafish Mouse Worm Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.042
digestive tract development GO:0048565 265 0.042
Zebrafish Mouse Worm Fly
midbrain hindbrain boundary development GO:0030917 23 0.042
heart morphogenesis GO:0003007 156 0.041
extrinsic apoptotic signaling pathway GO:0097191 3 0.041
Mouse
cell fate specification GO:0001708 68 0.041
Zebrafish Mouse Fly
determination of heart left right asymmetry GO:0061371 117 0.041
Zebrafish
embryonic eye morphogenesis GO:0048048 30 0.041
positive regulation of nucleic acid templated transcription GO:1903508 57 0.040
Rat
negative regulation of transcription dna templated GO:0045892 45 0.040
Mouse
lateral inhibition GO:0046331 1 0.039
immune system process GO:0002376 241 0.039
Fly
hepaticobiliary system development GO:0061008 98 0.039
Zebrafish
biological adhesion GO:0022610 40 0.039
striated muscle cell development GO:0055002 108 0.039
Fly
blood vessel morphogenesis GO:0048514 216 0.039
Mouse
sequestering of metal ion GO:0051238 3 0.038
hindbrain development GO:0030902 91 0.038
extracellular matrix organization GO:0030198 27 0.038
regulation of transcription dna templated GO:0006355 213 0.037
Mouse Rat
negative regulation of cell projection organization GO:0031345 9 0.037
Fly
osteoclast differentiation GO:0030316 1 0.037
endodermal cell fate determination GO:0007493 2 0.037
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.036
vasculature development GO:0001944 278 0.036
Mouse
tube closure GO:0060606 1 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
Mouse Rat
non canonical wnt signaling pathway GO:0035567 13 0.036
embryonic heart tube morphogenesis GO:0003143 108 0.036
regulation of developmental process GO:0050793 247 0.036
Human Zebrafish Mouse Rat Fly
lipid storage GO:0019915 1 0.036
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.036
cell cell recognition GO:0009988 1 0.036
stem cell proliferation GO:0072089 4 0.035
Mouse Rat
gtp catabolic process GO:0006184 2 0.035
epithelial tube formation GO:0072175 19 0.035
regulation of protein metabolic process GO:0051246 56 0.035
Human Fly
regulation of collateral sprouting GO:0048670 7 0.035
regulation of behavior GO:0050795 24 0.034
regulation of biological quality GO:0065008 263 0.034
Zebrafish Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.034
Human Rat Fly
regulation of myelination GO:0031641 1 0.034
positive regulation of cell fate commitment GO:0010455 1 0.034
smoothened signaling pathway GO:0007224 30 0.034
neuron projection regeneration GO:0031102 16 0.033
rna biosynthetic process GO:0032774 181 0.033
Mouse Rat
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.033
response to fibroblast growth factor GO:0071774 22 0.033
Human Zebrafish Mouse Worm
regulation of phospholipase activity GO:0010517 2 0.033
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.033
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.032
Zebrafish Rat Fly
larval development GO:0002164 2 0.032
Worm Fly
phagocytosis engulfment GO:0006911 1 0.032
Worm
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
bone development GO:0060348 14 0.032
positive regulation of signal transduction GO:0009967 56 0.032
Human Mouse Fly
retina morphogenesis in camera type eye GO:0060042 79 0.032
protein secretion GO:0009306 1 0.032
response to inorganic substance GO:0010035 38 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
negative regulation of metabolic process GO:0009892 86 0.031
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.031
positive regulation of bmp signaling pathway GO:0030513 10 0.031
reproductive structure development GO:0048608 5 0.031
Worm Fly
regulation of protein modification process GO:0031399 29 0.030
Human Fly
kidney epithelium development GO:0072073 23 0.030
Mouse
response to oxygen containing compound GO:1901700 55 0.030
specification of axis polarity GO:0065001 4 0.030
glandular epithelial cell differentiation GO:0002067 9 0.030
negative regulation of rna metabolic process GO:0051253 48 0.030
Mouse
endocrine system development GO:0035270 65 0.029
cell fate commitment GO:0045165 99 0.029
Zebrafish Mouse Fly
motor neuron axon guidance GO:0008045 23 0.029
activation of mapk activity GO:0000187 3 0.029
Fly
morphogenesis of a branching structure GO:0001763 21 0.028
Mouse Fly
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.028
ectodermal placode morphogenesis GO:0071697 32 0.028
Zebrafish
locomotion GO:0040011 313 0.028
Rat Worm Fly
protein complex subunit organization GO:0071822 46 0.028
developmental growth involved in morphogenesis GO:0060560 86 0.028
Fly
positive regulation of phospholipase c activity GO:0010863 1 0.028
Human
immune effector process GO:0002252 23 0.028
nephron development GO:0072006 31 0.028
regulation of cytoplasmic transport GO:1903649 4 0.028
negative regulation of rna biosynthetic process GO:1902679 45 0.027
Mouse
collateral sprouting of intact axon in response to injury GO:0048673 2 0.027
gland morphogenesis GO:0022612 13 0.027
Mouse
macromolecular complex subunit organization GO:0043933 74 0.027
negative regulation of mitosis GO:0045839 3 0.026
ras protein signal transduction GO:0007265 7 0.026
negative regulation of nervous system development GO:0051961 22 0.026
Fly
paraxial mesoderm development GO:0048339 8 0.026
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 13 0.026
response to lipid GO:0033993 60 0.026
endoderm development GO:0007492 49 0.026
Zebrafish Fly
organic acid biosynthetic process GO:0016053 12 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
radial glial cell differentiation GO:0060019 2 0.025
multicellular organism reproduction GO:0032504 35 0.025
Worm Fly
response to organic substance GO:0010033 153 0.025
Human Zebrafish Mouse Worm
negative regulation of sequestering of calcium ion GO:0051283 4 0.025
dorsal ventral axis specification GO:0009950 14 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
spinal cord patterning GO:0021511 6 0.025
cell fate commitment involved in pattern specification GO:0060581 6 0.025
multicellular organism growth GO:0035264 4 0.025
optic placode formation GO:0001743 4 0.025
pronephros development GO:0048793 69 0.024
forebrain regionalization GO:0021871 4 0.024
cellular component movement GO:0006928 335 0.024
Rat Worm Fly
multicellular organismal reproductive process GO:0048609 35 0.024
Worm Fly
regulation of phosphate metabolic process GO:0019220 43 0.024
Human Mouse Fly
positive regulation of striated muscle tissue development GO:0045844 1 0.024
Mouse
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.024
negative regulation of neurogenesis GO:0050768 20 0.024
Fly
i kappab kinase nf kappab signaling GO:0007249 4 0.024
small gtpase mediated signal transduction GO:0007264 8 0.024
epithelial cell development GO:0002064 42 0.024
Mouse Fly
palate development GO:0060021 8 0.024
convergent extension involved in axis elongation GO:0060028 26 0.024
positive regulation of neural precursor cell proliferation GO:2000179 1 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
defense response GO:0006952 47 0.024
Fly
hemopoiesis GO:0030097 183 0.023
cytosolic calcium ion transport GO:0060401 3 0.023
regulation of sequestering of calcium ion GO:0051282 4 0.023
positive regulation of cell proliferation GO:0008284 15 0.023
Human Mouse Rat
cytoskeleton organization GO:0007010 96 0.023
death GO:0016265 121 0.023
Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.023
photoreceptor cell differentiation GO:0046530 55 0.023
nucleotide biosynthetic process GO:0009165 21 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
Mouse Rat
response to wounding GO:0009611 116 0.023
Zebrafish
central nervous system myelination GO:0022010 2 0.022
mononuclear cell proliferation GO:0032943 1 0.022
negative regulation of gastrulation GO:2000542 11 0.022
Zebrafish
positive regulation of neuron apoptotic process GO:0043525 1 0.022
forebrain generation of neurons GO:0021872 14 0.022
Mouse Rat
negative regulation of nuclear division GO:0051784 3 0.022
protein import into nucleus GO:0006606 3 0.022
regulation of cardiac muscle tissue development GO:0055024 1 0.022
Mouse
regulation of lipase activity GO:0060191 2 0.022
Human
catenin import into nucleus GO:0035411 2 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of cell proliferation GO:0042127 37 0.022
Human Mouse Rat
cellular ketone metabolic process GO:0042180 11 0.022
habenula development GO:0021986 9 0.022
amine metabolic process GO:0009308 2 0.021
ear development GO:0043583 127 0.021
Mouse
calcium ion transport into cytosol GO:0060402 3 0.021
negative regulation of cell development GO:0010721 26 0.021
Fly
regulation of reproductive process GO:2000241 4 0.021
appendage development GO:0048736 80 0.021
Mouse
regulation of protein transport GO:0051223 3 0.021
organ formation GO:0048645 17 0.021
Mouse
growth plate cartilage development GO:0003417 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
organelle organization GO:0006996 227 0.020
Zebrafish
growth GO:0040007 174 0.020
Zebrafish Mouse Fly
pronephric nephron development GO:0039019 14 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
nephron epithelium development GO:0072009 16 0.020
negative regulation of neuron differentiation GO:0045665 10 0.020
Fly
positive regulation of response to stimulus GO:0048584 80 0.020
Human Mouse Fly
positive regulation of phosphorus metabolic process GO:0010562 21 0.020
Human Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
Worm Fly
camera type eye photoreceptor cell differentiation GO:0060219 19 0.019
regulation of catalytic activity GO:0050790 55 0.019
Human Fly
cellular amino acid metabolic process GO:0006520 7 0.019
water homeostasis GO:0030104 4 0.019
regulation of nervous system development GO:0051960 90 0.019
Human Mouse Rat Fly
regulation of cell activation GO:0050865 1 0.019
anatomical structure homeostasis GO:0060249 36 0.019
Zebrafish
lymphatic endothelial cell differentiation GO:0060836 1 0.019
negative regulation of axon guidance GO:1902668 1 0.019
cellular response to lipopolysaccharide GO:0071222 3 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
negative regulation of developmental growth GO:0048640 9 0.019
Fly
positive regulation of ras protein signal transduction GO:0046579 1 0.019
regulation of collateral sprouting in absence of injury GO:0048696 4 0.019
single organism localization GO:1902578 225 0.018
Worm
cellular amine metabolic process GO:0044106 2 0.018
regulation of oligodendrocyte differentiation GO:0048713 1 0.018
retinoic acid metabolic process GO:0042573 9 0.018
urogenital system development GO:0001655 97 0.018
Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.018
Rat
intracellular receptor signaling pathway GO:0030522 30 0.018
positive regulation of synapse assembly GO:0051965 1 0.018
extracellular structure organization GO:0043062 27 0.018
gall bladder development GO:0061010 1 0.018
embryonic camera type eye morphogenesis GO:0048596 19 0.018
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.018
retina development in camera type eye GO:0060041 146 0.018
hepatic duct development GO:0061011 2 0.017
cell activation GO:0001775 16 0.017
tissue remodeling GO:0048771 4 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.017
positive regulation of molecular function GO:0044093 33 0.017
Human Fly
actin cytoskeleton organization GO:0030036 63 0.017
regulation of endothelial cell proliferation GO:0001936 1 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
b cell differentiation GO:0030183 1 0.017
muscle organ development GO:0007517 101 0.016
Mouse Worm Fly
bone remodeling GO:0046849 2 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
Mouse
lymphocyte proliferation GO:0046651 1 0.016
response to carbohydrate GO:0009743 3 0.016
peripheral nervous system neuron differentiation GO:0048934 28 0.016
oligodendrocyte differentiation GO:0048709 23 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
positive regulation of gene expression GO:0010628 71 0.016
Rat
positive regulation of developmental process GO:0051094 50 0.016
Human Mouse Rat
axon midline choice point recognition GO:0016199 4 0.016
behavior GO:0007610 74 0.016
Worm
regulation of molecular function GO:0065009 70 0.016
Human Fly
neuroblast fate commitment GO:0014017 1 0.016
regulation of establishment of protein localization GO:0070201 4 0.015
cellular response to prostaglandin stimulus GO:0071379 3 0.015
stem cell fate commitment GO:0048865 1 0.015
neuroblast fate determination GO:0007400 1 0.015
collateral sprouting in absence of injury GO:0048669 4 0.015
cell proliferation in hindbrain GO:0021534 4 0.015

fgfr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.239
Human
endocrine system disease DOID:28 0 0.239
Human
cancer DOID:162 0 0.096
disease of cellular proliferation DOID:14566 0 0.096
gastrointestinal system cancer DOID:3119 0 0.038
organ system cancer DOID:0050686 0 0.038
large intestine cancer DOID:5672 0 0.023
intestinal cancer DOID:10155 0 0.023
colorectal cancer DOID:9256 0 0.023