Danio rerio

0 known processes

mthfd1

methylenetetrahydrofolate dehydrogenase (NADP+ dependent)

(Aliases: zgc:55597,cb325)

mthfd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 3 0.665
cellular amino acid biosynthetic process GO:0008652 2 0.613
methylation GO:0032259 22 0.209
biosynthetic process GO:0009058 294 0.163
organonitrogen compound biosynthetic process GO:1901566 47 0.128
pyrimidine containing compound metabolic process GO:0072527 3 0.126
cellular modified amino acid metabolic process GO:0006575 3 0.122
s adenosylmethionine metabolic process GO:0046500 1 0.081
small molecule biosynthetic process GO:0044283 16 0.079
larval development GO:0002164 2 0.076
cellular nitrogen compound metabolic process GO:0034641 290 0.075
adult behavior GO:0030534 2 0.071
regulation of multicellular organismal process GO:0051239 277 0.070
oxoacid metabolic process GO:0043436 31 0.067
maintenance of location GO:0051235 4 0.066
organic acid metabolic process GO:0006082 31 0.063
microtubule organizing center organization GO:0031023 1 0.063
carboxylic acid metabolic process GO:0019752 22 0.061
single organism biosynthetic process GO:0044711 71 0.060
multicellular organism growth GO:0035264 4 0.060
ion transport GO:0006811 114 0.060
cellular amino acid metabolic process GO:0006520 7 0.059
lipid storage GO:0019915 1 0.058
carbohydrate derivative metabolic process GO:1901135 61 0.055
organic substance biosynthetic process GO:1901576 289 0.054
locomotion GO:0040011 313 0.052
nucleobase containing compound biosynthetic process GO:0034654 205 0.051
positive regulation of cellular catabolic process GO:0031331 3 0.051
sulfur compound biosynthetic process GO:0044272 9 0.049
tube morphogenesis GO:0035239 349 0.048
brain development GO:0007420 293 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
small molecule metabolic process GO:0044281 77 0.043
eye development GO:0001654 277 0.040
heart development GO:0007507 313 0.040
cellular biosynthetic process GO:0044249 286 0.039
nitrogen compound metabolic process GO:0006807 319 0.039
zymogen activation GO:0031638 3 0.038
lipid oxidation GO:0034440 1 0.035
chordate embryonic development GO:0043009 271 0.035
aging GO:0007568 2 0.034
aromatic compound biosynthetic process GO:0019438 217 0.032
regulation of multicellular organism growth GO:0040014 4 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
positive regulation of catabolic process GO:0009896 4 0.030
sensory organ development GO:0007423 393 0.028
nephron tubule morphogenesis GO:0072078 1 0.028
negative regulation of biological process GO:0048519 304 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
carboxylic acid catabolic process GO:0046395 3 0.027
amine metabolic process GO:0009308 2 0.026
centrosome organization GO:0051297 1 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.025
cofactor metabolic process GO:0051186 15 0.025
single organism metabolic process GO:0044710 217 0.025
epithelial tube morphogenesis GO:0060562 148 0.022
generation of neurons GO:0048699 385 0.022
ribosome assembly GO:0042255 1 0.022
carboxylic acid biosynthetic process GO:0046394 12 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
heterocycle metabolic process GO:0046483 290 0.020
regulation of biological quality GO:0065008 263 0.020
pteridine containing compound metabolic process GO:0042558 3 0.020
long chain fatty acid transport GO:0015909 1 0.019
negative regulation of mrna metabolic process GO:1903312 3 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
head development GO:0060322 303 0.019
dicarboxylic acid metabolic process GO:0043648 1 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
negative regulation of catabolic process GO:0009895 3 0.018
digestive system development GO:0055123 289 0.018
specification of symmetry GO:0009799 204 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
cellular response to organic cyclic compound GO:0071407 38 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
regulation of reproductive process GO:2000241 4 0.017
digestive tract development GO:0048565 265 0.017
central nervous system development GO:0007417 387 0.017
purine containing compound metabolic process GO:0072521 29 0.017
regulation of metabolic process GO:0019222 359 0.017
single organism transport GO:0044765 206 0.017
nucleobase containing small molecule metabolic process GO:0055086 32 0.017
deoxyribonucleotide biosynthetic process GO:0009263 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
sulfur compound metabolic process GO:0006790 13 0.016
oxidoreduction coenzyme metabolic process GO:0006733 1 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
positive regulation of biological process GO:0048518 253 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
response to lipid GO:0033993 60 0.015
organic acid catabolic process GO:0016054 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
response to amino acid GO:0043200 2 0.014
protein localization to nucleus GO:0034504 3 0.014
camera type eye development GO:0043010 222 0.013
negative regulation of kinase activity GO:0033673 4 0.013
organophosphate metabolic process GO:0019637 37 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
cell proliferation GO:0008283 80 0.013
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.013
developmental growth GO:0048589 166 0.013
organic acid biosynthetic process GO:0016053 12 0.013
cellular amine metabolic process GO:0044106 2 0.013
striated muscle tissue development GO:0014706 110 0.013
liver development GO:0001889 96 0.012
cyclic nucleotide metabolic process GO:0009187 18 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
regulation of jun kinase activity GO:0043506 3 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
hepaticobiliary system development GO:0061008 98 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
fatty acid oxidation GO:0019395 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
rna biosynthetic process GO:0032774 181 0.012
coenzyme metabolic process GO:0006732 5 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
rna localization GO:0006403 4 0.011
neuron differentiation GO:0030182 353 0.011
b cell mediated immunity GO:0019724 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
mononuclear cell proliferation GO:0032943 1 0.011
nuclear export GO:0051168 1 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
circulatory system process GO:0003013 87 0.011
centrosome cycle GO:0007098 1 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
deoxyribose phosphate metabolic process GO:0019692 1 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of organelle assembly GO:1902115 4 0.010
myeloid leukocyte migration GO:0097529 12 0.010
regulation of blood pressure GO:0008217 1 0.010
digestive tract morphogenesis GO:0048546 231 0.010
somatic muscle development GO:0007525 4 0.010
amino acid transport GO:0006865 2 0.010
phosphorus metabolic process GO:0006793 109 0.010

mthfd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.046
inherited metabolic disorder DOID:655 0 0.046
disease of anatomical entity DOID:7 0 0.019
amino acid metabolic disorder DOID:9252 0 0.016
x linked disease DOID:0050735 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010