Danio rerio

0 known processes

zgc:112393

zgc:112393

zgc:112393 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.106
aging GO:0007568 2 0.056
multicellular organism growth GO:0035264 4 0.055
autophagy GO:0006914 4 0.044
regulation of multicellular organism growth GO:0040014 4 0.043
maintenance of location GO:0051235 4 0.038
endosomal transport GO:0016197 2 0.035
phagocytosis GO:0006909 3 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
Rat
membrane fusion GO:0061025 2 0.034
Yeast
meiotic nuclear division GO:0007126 4 0.033
response to chemical GO:0042221 320 0.033
Rat
organelle fusion GO:0048284 3 0.033
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
signal transduction GO:0007165 455 0.032
single organism metabolic process GO:0044710 217 0.031
positive regulation of cell cycle GO:0045787 3 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
Rat
mitochondrion organization GO:0007005 4 0.031
sensory organ development GO:0007423 393 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
positive regulation of transport GO:0051050 2 0.030
establishment of localization GO:0051234 244 0.030
cytokinesis GO:0000910 3 0.030
nitrogen compound metabolic process GO:0006807 319 0.029
Rat
guanosine containing compound catabolic process GO:1901069 2 0.029
cognition GO:0050890 1 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
cellular response to nutrient levels GO:0031669 2 0.028
single organism transport GO:0044765 206 0.028
amine metabolic process GO:0009308 2 0.028
lipid storage GO:0019915 1 0.028
modification dependent protein catabolic process GO:0019941 3 0.027
transport GO:0006810 220 0.027
cellular amine metabolic process GO:0044106 2 0.027
regulation of metabolic process GO:0019222 359 0.026
Rat
cellular protein catabolic process GO:0044257 4 0.026
gene expression GO:0010467 252 0.026
Yeast Rat
nucleic acid metabolic process GO:0090304 244 0.026
Rat
stem cell proliferation GO:0072089 4 0.026
cellular component morphogenesis GO:0032989 336 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
neuron differentiation GO:0030182 353 0.025
single organism membrane fusion GO:0044801 2 0.025
Yeast
cellular response to starvation GO:0009267 1 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
cellular response to external stimulus GO:0071496 2 0.024
heterocycle metabolic process GO:0046483 290 0.024
Rat
cellular macromolecule metabolic process GO:0044260 391 0.024
Human Yeast Mouse Rat
regulation of cell communication GO:0010646 232 0.024
regulation of protein complex assembly GO:0043254 3 0.024
tissue remodeling GO:0048771 4 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
Rat
small molecule metabolic process GO:0044281 77 0.024
regulation of signaling GO:0023051 235 0.024
regulation of response to stimulus GO:0048583 269 0.024
positive regulation of catabolic process GO:0009896 4 0.023
positive regulation of biological process GO:0048518 253 0.023
Rat
rna localization GO:0006403 4 0.023
cellular component movement GO:0006928 335 0.023
regulation of protein transport GO:0051223 3 0.023
atp catabolic process GO:0006200 4 0.023
regulation of metal ion transport GO:0010959 4 0.023
response to drug GO:0042493 3 0.023
gtp metabolic process GO:0046039 4 0.023
regulation of cytokine production GO:0001817 3 0.022
single organism localization GO:1902578 225 0.022
eye development GO:0001654 277 0.022
cell projection organization GO:0030030 284 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
Rat
embryonic organ development GO:0048568 381 0.022
gtp catabolic process GO:0006184 2 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
adult behavior GO:0030534 2 0.021
response to stress GO:0006950 263 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
Rat
negative regulation of cellular process GO:0048523 283 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
negative regulation of biological process GO:0048519 304 0.021
golgi vesicle transport GO:0048193 3 0.021
cell part morphogenesis GO:0032990 246 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
protein acetylation GO:0006473 2 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
cellular amide metabolic process GO:0043603 4 0.020
protein localization to nucleus GO:0034504 3 0.020
regulation of signal transduction GO:0009966 225 0.020
locomotion GO:0040011 313 0.020
protein import GO:0017038 3 0.020
neuron development GO:0048666 262 0.020
generation of neurons GO:0048699 385 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of biological quality GO:0065008 263 0.020
Fly
stem cell maintenance GO:0019827 4 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
nuclear transport GO:0051169 4 0.020
organelle organization GO:0006996 227 0.020
Yeast
regulation of cytoplasmic transport GO:1903649 4 0.020
exocytosis GO:0006887 1 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.019
protein metabolic process GO:0019538 183 0.019
Human Yeast Mouse Rat
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of protein catabolic process GO:0042176 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
nuclear import GO:0051170 3 0.019
protein targeting to nucleus GO:0044744 3 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
Rat
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
organic substance biosynthetic process GO:1901576 289 0.018
Rat
meiotic cell cycle process GO:1903046 3 0.018
response to external stimulus GO:0009605 264 0.018
rna metabolic process GO:0016070 219 0.018
Rat
cellular component assembly GO:0022607 170 0.018
cell morphogenesis GO:0000902 289 0.018
neurotransmitter secretion GO:0007269 2 0.018
cellular component biogenesis GO:0044085 178 0.018
organic acid metabolic process GO:0006082 31 0.018
single organism nuclear import GO:1902593 3 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
positive regulation of secretion GO:0051047 1 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
regulation of binding GO:0051098 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
Rat
aromatic compound biosynthetic process GO:0019438 217 0.018
Rat
regulation of nucleotide catabolic process GO:0030811 2 0.017
homeostatic process GO:0042592 142 0.017
camera type eye development GO:0043010 222 0.017
regulation of reproductive process GO:2000241 4 0.017
protein import into nucleus GO:0006606 3 0.017
centrosome organization GO:0051297 1 0.017
regulation of primary metabolic process GO:0080090 311 0.017
Rat
synaptic growth at neuromuscular junction GO:0051124 2 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
Rat
sequestering of calcium ion GO:0051208 3 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
cellular ketone metabolic process GO:0042180 11 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
protein localization to plasma membrane GO:0072659 1 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
cellular biosynthetic process GO:0044249 286 0.017
Rat
internal peptidyl lysine acetylation GO:0018393 2 0.016
compound eye development GO:0048749 2 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
positive regulation of cellular process GO:0048522 201 0.016
Rat
immune system process GO:0002376 241 0.016
regulation of cell activation GO:0050865 1 0.016
cellular response to radiation GO:0071478 4 0.016
alcohol biosynthetic process GO:0046165 2 0.016
system process GO:0003008 185 0.016
transcription dna templated GO:0006351 181 0.016
Rat
regulation of gene expression GO:0010468 265 0.016
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.016
Rat
cell migration GO:0016477 237 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
positive regulation of protein complex assembly GO:0031334 2 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Rat
heterocycle biosynthetic process GO:0018130 215 0.015
Rat
regulation of cellular ketone metabolic process GO:0010565 7 0.015
biosynthetic process GO:0009058 294 0.015
Rat
regulation of protein targeting GO:1903533 2 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
transmembrane transport GO:0055085 120 0.015
single organism organelle organization GO:1902589 199 0.015
Yeast
regulation of dendrite development GO:0050773 3 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
ion transport GO:0006811 114 0.015
protein secretion GO:0009306 1 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
Rat
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
Rat
chordate embryonic development GO:0043009 271 0.015
protein acylation GO:0043543 3 0.015
primary neural tube formation GO:0014020 1 0.015
nucleic acid templated transcription GO:0097659 181 0.015
Rat
cellular component disassembly GO:0022411 1 0.015
sequestering of metal ion GO:0051238 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
Rat
regionalization GO:0003002 274 0.014
synaptic vesicle localization GO:0097479 1 0.014
cell substrate adhesion GO:0031589 4 0.014
response to uv GO:0009411 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
spermatid development GO:0007286 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
digestive tract development GO:0048565 265 0.014
regulation of synapse organization GO:0050807 3 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
meiotic chromosome segregation GO:0045132 3 0.014
secondary metabolic process GO:0019748 3 0.014
neurotransmitter transport GO:0006836 2 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
negative regulation of protein transport GO:0051224 3 0.014
neuron projection development GO:0031175 180 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
double strand break repair GO:0006302 3 0.014
spermatid differentiation GO:0048515 2 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
Rat
regulation of cellular biosynthetic process GO:0031326 245 0.014
Rat
central nervous system development GO:0007417 387 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
viral process GO:0016032 1 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
phagocytosis engulfment GO:0006911 1 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
stem cell division GO:0017145 1 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
neuroblast proliferation GO:0007405 2 0.013
rna modification GO:0009451 2 0.013
immune system development GO:0002520 191 0.013
apoptotic process GO:0006915 116 0.013
female sex differentiation GO:0046660 4 0.013
ion transmembrane transport GO:0034220 91 0.013
membrane invagination GO:0010324 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
negative regulation of catabolic process GO:0009895 3 0.013
response to monosaccharide GO:0034284 3 0.013
peptide metabolic process GO:0006518 1 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
skeletal system development GO:0001501 181 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
leukocyte proliferation GO:0070661 1 0.013
response to topologically incorrect protein GO:0035966 2 0.013
synaptic vesicle transport GO:0048489 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
peptidyl serine modification GO:0018209 2 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
germ line stem cell maintenance GO:0030718 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of calcium ion transport GO:0051924 2 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
Human Mouse Rat
protein polyubiquitination GO:0000209 4 0.013
protein dephosphorylation GO:0006470 3 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
macroautophagy GO:0016236 1 0.013
growth GO:0040007 174 0.013
response to organic substance GO:0010033 153 0.013
Rat
regulation of epithelial cell proliferation GO:0050678 3 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human Mouse Rat
cellular response to molecule of bacterial origin GO:0071219 3 0.013
protein homooligomerization GO:0051260 3 0.013
rna biosynthetic process GO:0032774 181 0.013
Rat
response to hydrogen peroxide GO:0042542 3 0.013
small molecule catabolic process GO:0044282 3 0.013
hemopoiesis GO:0030097 183 0.012
tube closure GO:0060606 1 0.012
heart development GO:0007507 313 0.012
multi organism process GO:0051704 134 0.012
developmental growth GO:0048589 166 0.012
regulation of mrna processing GO:0050684 3 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
Rat
regulation of inflammatory response GO:0050727 2 0.012
positive regulation of cell activation GO:0050867 1 0.012
lipid catabolic process GO:0016042 4 0.012
vasculature development GO:0001944 278 0.012
tube morphogenesis GO:0035239 349 0.012
cellular protein modification process GO:0006464 100 0.012
Human Mouse Rat
response to hexose GO:0009746 3 0.012
vacuolar transport GO:0007034 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
recombinational repair GO:0000725 1 0.012
response to carbohydrate GO:0009743 3 0.012
intracellular signal transduction GO:0035556 85 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
organic acid catabolic process GO:0016054 3 0.012
digestive system development GO:0055123 289 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
cellular response to light stimulus GO:0071482 4 0.012
lateral inhibition GO:0046331 1 0.012
muscle structure development GO:0061061 196 0.012
translational initiation GO:0006413 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
macromolecule modification GO:0043412 111 0.011
Human Mouse Rat
cellular protein metabolic process GO:0044267 129 0.011
Human Yeast Mouse Rat
regulation of transcription dna templated GO:0006355 213 0.011
Rat
post golgi vesicle mediated transport GO:0006892 1 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
mitotic cytokinesis GO:0000281 3 0.011
cellular lipid catabolic process GO:0044242 3 0.011
head development GO:0060322 303 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
response to glucose GO:0009749 3 0.011
organelle assembly GO:0070925 110 0.011
axonogenesis GO:0007409 152 0.011
peptide transport GO:0015833 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
Rat
regulation of synapse assembly GO:0051963 3 0.011
axon development GO:0061564 166 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
nucleic acid transport GO:0050657 2 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
pigmentation GO:0043473 85 0.011
macromolecular complex disassembly GO:0032984 1 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of exocytosis GO:0017157 1 0.011
cellular response to organic substance GO:0071310 105 0.011
Rat
blood vessel development GO:0001568 246 0.011
brain development GO:0007420 293 0.011
b cell activation GO:0042113 2 0.011
mitochondrial transport GO:0006839 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of blood pressure GO:0008217 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
Rat
programmed cell death GO:0012501 119 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
somatic muscle development GO:0007525 4 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.010
carboxylic acid catabolic process GO:0046395 3 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
establishment of rna localization GO:0051236 3 0.010
cellular transition metal ion homeostasis GO:0046916 3 0.010
regulation of apoptotic process GO:0042981 98 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
death GO:0016265 121 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
response to corticosteroid GO:0031960 1 0.010
glucose homeostasis GO:0042593 1 0.010
positive regulation of multi organism process GO:0043902 3 0.010
cell substrate junction assembly GO:0007044 2 0.010
intracellular mrna localization GO:0008298 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
centrosome cycle GO:0007098 1 0.010
response to alkaloid GO:0043279 2 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.010
localization of cell GO:0051674 244 0.010
response to nutrient GO:0007584 3 0.010
cellular respiration GO:0045333 3 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of rna metabolic process GO:0051252 224 0.010
Rat
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010

zgc:112393 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.019
inherited metabolic disorder DOID:655 0 0.017
disease of metabolism DOID:0014667 0 0.017
musculoskeletal system disease DOID:17 0 0.017
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010