Danio rerio

0 known processes

rasgef1bb

RasGEF domain family, member 1Bb

(Aliases: wu:fc34e01,zgc:91814,im:7136415,rasgef,fc34e01)

rasgef1bb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing compound metabolic process GO:0006139 274 0.391
regulation of nitrogen compound metabolic process GO:0051171 251 0.324
organic cyclic compound biosynthetic process GO:1901362 223 0.251
aromatic compound biosynthetic process GO:0019438 217 0.250
rna metabolic process GO:0016070 219 0.213
negative regulation of biological process GO:0048519 304 0.212
nitrogen compound metabolic process GO:0006807 319 0.199
establishment of localization GO:0051234 244 0.198
cellular biosynthetic process GO:0044249 286 0.197
organic cyclic compound metabolic process GO:1901360 301 0.197
gene expression GO:0010467 252 0.183
signal transduction GO:0007165 455 0.180
cellular nitrogen compound biosynthetic process GO:0044271 218 0.175
negative regulation of cellular process GO:0048523 283 0.171
transcription dna templated GO:0006351 181 0.164
regulation of cellular metabolic process GO:0031323 320 0.161
regulation of response to stimulus GO:0048583 269 0.160
cellular aromatic compound metabolic process GO:0006725 295 0.158
macromolecule biosynthetic process GO:0009059 227 0.148
cellular macromolecule biosynthetic process GO:0034645 224 0.148
nucleic acid templated transcription GO:0097659 181 0.147
regulation of biosynthetic process GO:0009889 250 0.146
regulation of metabolic process GO:0019222 359 0.143
biosynthetic process GO:0009058 294 0.142
regulation of cellular biosynthetic process GO:0031326 245 0.141
regulation of multicellular organismal process GO:0051239 277 0.135
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.131
regulation of macromolecule metabolic process GO:0060255 317 0.128
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.125
regulation of macromolecule biosynthetic process GO:0010556 225 0.124
neuron differentiation GO:0030182 353 0.123
nucleic acid metabolic process GO:0090304 244 0.122
embryonic organ development GO:0048568 381 0.121
rna biosynthetic process GO:0032774 181 0.115
nucleobase containing compound biosynthetic process GO:0034654 205 0.112
blood vessel morphogenesis GO:0048514 216 0.106
organic substance biosynthetic process GO:1901576 289 0.099
regulation of primary metabolic process GO:0080090 311 0.098
regulation of gene expression GO:0010468 265 0.097
regulation of signal transduction GO:0009966 225 0.096
aging GO:0007568 2 0.094
positive regulation of macromolecule metabolic process GO:0010604 93 0.091
regulation of nucleic acid templated transcription GO:1903506 213 0.088
lipid storage GO:0019915 1 0.087
meiotic nuclear division GO:0007126 4 0.086
regulation of rna metabolic process GO:0051252 224 0.085
cellular macromolecule metabolic process GO:0044260 391 0.085
generation of neurons GO:0048699 385 0.085
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.078
cellular component movement GO:0006928 335 0.078
single organism metabolic process GO:0044710 217 0.076
locomotion GO:0040011 313 0.076
regulation of signaling GO:0023051 235 0.073
cellular nitrogen compound metabolic process GO:0034641 290 0.072
regulation of cell communication GO:0010646 232 0.072
heterocycle metabolic process GO:0046483 290 0.070
ameboidal type cell migration GO:0001667 143 0.070
response to stress GO:0006950 263 0.067
modification dependent macromolecule catabolic process GO:0043632 3 0.065
transcription from rna polymerase ii promoter GO:0006366 80 0.063
heterocycle biosynthetic process GO:0018130 215 0.063
maintenance of location GO:0051235 4 0.062
negative regulation of cellular metabolic process GO:0031324 77 0.061
negative regulation of metabolic process GO:0009892 86 0.061
amine metabolic process GO:0009308 2 0.060
regulation of rna biosynthetic process GO:2001141 213 0.059
response to chemical GO:0042221 320 0.058
appendage development GO:0048736 80 0.057
protein modification process GO:0036211 100 0.056
regulation of developmental process GO:0050793 247 0.054
cell motility GO:0048870 244 0.053
negative regulation of signal transduction GO:0009968 94 0.053
regulation of multicellular organism growth GO:0040014 4 0.053
small molecule metabolic process GO:0044281 77 0.053
cell surface receptor signaling pathway GO:0007166 325 0.052
modification dependent protein catabolic process GO:0019941 3 0.051
g1 s transition of mitotic cell cycle GO:0000082 1 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.050
regulation of apoptotic process GO:0042981 98 0.050
positive regulation of catabolic process GO:0009896 4 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.050
regulation of inflammatory response GO:0050727 2 0.050
negative regulation of macromolecule metabolic process GO:0010605 76 0.049
heart development GO:0007507 313 0.049
vasculature development GO:0001944 278 0.048
regionalization GO:0003002 274 0.048
cellular component morphogenesis GO:0032989 336 0.048
tube morphogenesis GO:0035239 349 0.047
positive regulation of cellular process GO:0048522 201 0.047
cellular amino acid metabolic process GO:0006520 7 0.047
larval development GO:0002164 2 0.047
meiotic cell cycle process GO:1903046 3 0.046
positive regulation of biological process GO:0048518 253 0.046
macromolecule modification GO:0043412 111 0.045
eye development GO:0001654 277 0.044
negative regulation of gene expression GO:0010629 65 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.043
cell death GO:0008219 121 0.043
response to wounding GO:0009611 116 0.043
regulation of reproductive process GO:2000241 4 0.042
mesenchyme development GO:0060485 127 0.042
response to organic substance GO:0010033 153 0.042
regulation of meiotic cell cycle GO:0051445 1 0.042
positive regulation of biosynthetic process GO:0009891 68 0.042
cellular protein metabolic process GO:0044267 129 0.042
multicellular organism growth GO:0035264 4 0.041
cellular protein modification process GO:0006464 100 0.041
negative regulation of response to stimulus GO:0048585 104 0.041
phosphate containing compound metabolic process GO:0006796 108 0.040
system process GO:0003008 185 0.040
oxoacid metabolic process GO:0043436 31 0.040
regulation of metal ion transport GO:0010959 4 0.040
positive regulation of cell cycle GO:0045787 3 0.039
blood vessel development GO:0001568 246 0.039
eye morphogenesis GO:0048592 144 0.039
protein metabolic process GO:0019538 183 0.039
positive regulation of cellular metabolic process GO:0031325 94 0.039
negative regulation of kinase activity GO:0033673 4 0.039
cellular response to external stimulus GO:0071496 2 0.038
cell substrate adhesion GO:0031589 4 0.038
cellular response to chemical stimulus GO:0070887 157 0.038
carboxylic acid metabolic process GO:0019752 22 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.037
organic acid metabolic process GO:0006082 31 0.037
regulation of localization GO:0032879 104 0.037
regulation of binding GO:0051098 3 0.037
mitotic cell cycle GO:0000278 64 0.036
positive regulation of gene expression GO:0010628 71 0.036
cellular response to radiation GO:0071478 4 0.036
cell cycle g1 s phase transition GO:0044843 1 0.035
determination of left right symmetry GO:0007368 179 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.035
transport GO:0006810 220 0.035
regulation of programmed cell death GO:0043067 101 0.035
positive regulation of apoptotic signaling pathway GO:2001235 1 0.034
cell migration GO:0016477 237 0.034
single organism localization GO:1902578 225 0.034
chordate embryonic development GO:0043009 271 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
response to carbohydrate GO:0009743 3 0.034
single organism transport GO:0044765 206 0.033
positive regulation of metabolic process GO:0009893 108 0.033
neuron projection development GO:0031175 180 0.033
response to glucose GO:0009749 3 0.033
negative regulation of cell communication GO:0010648 96 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
proteasomal protein catabolic process GO:0010498 2 0.032
localization of cell GO:0051674 244 0.031
camera type eye development GO:0043010 222 0.031
response to vitamin GO:0033273 3 0.031
cellular amine metabolic process GO:0044106 2 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.030
response to monosaccharide GO:0034284 3 0.030
skin development GO:0043588 54 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of biological quality GO:0065008 263 0.029
apoptotic process GO:0006915 116 0.029
peptidyl serine phosphorylation GO:0018105 1 0.029
cell proliferation GO:0008283 80 0.029
wound healing GO:0042060 90 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.028
erk1 and erk2 cascade GO:0070371 4 0.027
negative regulation of cellular biosynthetic process GO:0031327 55 0.027
sensory organ development GO:0007423 393 0.027
central nervous system development GO:0007417 387 0.027
determination of bilateral symmetry GO:0009855 204 0.027
death GO:0016265 121 0.027
embryonic limb morphogenesis GO:0030326 2 0.027
response to hexose GO:0009746 3 0.027
enzyme linked receptor protein signaling pathway GO:0007167 106 0.027
retina development in camera type eye GO:0060041 146 0.027
axonogenesis GO:0007409 152 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.026
cell aging GO:0007569 2 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
regulation of transcription dna templated GO:0006355 213 0.026
cellular response to organic substance GO:0071310 105 0.026
head development GO:0060322 303 0.026
multicellular organismal macromolecule metabolic process GO:0044259 2 0.025
epithelial cell migration GO:0010631 25 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
neuron development GO:0048666 262 0.025
tissue remodeling GO:0048771 4 0.024
positive regulation of transport GO:0051050 2 0.024
cell projection organization GO:0030030 284 0.024
neuron projection morphogenesis GO:0048812 161 0.024
negative regulation of signaling GO:0023057 96 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
regulation of system process GO:0044057 40 0.024
response to lipid GO:0033993 60 0.023
digestive system development GO:0055123 289 0.023
tissue migration GO:0090130 37 0.023
angiogenesis GO:0001525 158 0.023
negative regulation of rna biosynthetic process GO:1902679 45 0.023
organelle organization GO:0006996 227 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
transcription from rna polymerase iii promoter GO:0006383 1 0.022
growth GO:0040007 174 0.022
phosphorus metabolic process GO:0006793 109 0.022
response to abiotic stimulus GO:0009628 122 0.022
stem cell maintenance GO:0019827 4 0.022
defense response GO:0006952 47 0.021
cellular protein catabolic process GO:0044257 4 0.021
regulation of protein catabolic process GO:0042176 1 0.021
regulation of cytokine production GO:0001817 3 0.021
cell death in response to oxidative stress GO:0036473 2 0.021
protein phosphorylation GO:0006468 47 0.021
regulation of wound healing GO:0061041 2 0.021
cell part morphogenesis GO:0032990 246 0.021
response to external stimulus GO:0009605 264 0.021
cellular response to stress GO:0033554 62 0.021
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
response to nutrient GO:0007584 3 0.020
cellular component disassembly GO:0022411 1 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of cellular component movement GO:0051270 55 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
positive regulation of rna biosynthetic process GO:1902680 57 0.020
digestive tract development GO:0048565 265 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
camera type eye morphogenesis GO:0048593 108 0.020
regulation of cell development GO:0060284 100 0.020
positive regulation of multicellular organismal process GO:0051240 52 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
positive regulation of signaling GO:0023056 56 0.019
regulation of cell activation GO:0050865 1 0.019
female meiotic division GO:0007143 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
positive regulation of transcription dna templated GO:0045893 57 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
multicellular organismal metabolic process GO:0044236 2 0.019
programmed cell death GO:0012501 119 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
positive regulation of developmental process GO:0051094 50 0.019
positive regulation of signal transduction GO:0009967 56 0.019
skeletal muscle organ development GO:0060538 78 0.019
macromolecule localization GO:0033036 54 0.019
negative regulation of cell growth GO:0030308 7 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
embryonic heart tube development GO:0035050 133 0.018
somite development GO:0061053 96 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of dendrite development GO:0050773 3 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
regulation of calcium ion transport GO:0051924 2 0.018
cell projection morphogenesis GO:0048858 244 0.018
sensory organ morphogenesis GO:0090596 200 0.018
protein import GO:0017038 3 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
regulation of blood circulation GO:1903522 32 0.018
cellular response to light stimulus GO:0071482 4 0.018
anterior posterior pattern specification GO:0009952 152 0.018
adult behavior GO:0030534 2 0.018
axon development GO:0061564 166 0.018
epithelium migration GO:0090132 25 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
peptidyl serine modification GO:0018209 2 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
cellular component biogenesis GO:0044085 178 0.017
epidermis development GO:0008544 48 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
digestive tract morphogenesis GO:0048546 231 0.017
multi organism process GO:0051704 134 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
regulation of cell death GO:0010941 103 0.017
regulation of cell differentiation GO:0045595 142 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
nuclear transport GO:0051169 4 0.016
appendage morphogenesis GO:0035107 56 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
negative regulation of cell cycle GO:0045786 14 0.016
regulation of multicellular organismal metabolic process GO:0044246 2 0.016
homeostatic process GO:0042592 142 0.016
regulation of response to oxidative stress GO:1902882 2 0.016
brain development GO:0007420 293 0.016
nuclear import GO:0051170 3 0.016
cellular response to nutrient levels GO:0031669 2 0.016
specification of symmetry GO:0009799 204 0.016
skeletal system development GO:0001501 181 0.016
female sex differentiation GO:0046660 4 0.016
sexual reproduction GO:0019953 36 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
cell cycle GO:0007049 93 0.016
negative regulation of intracellular signal transduction GO:1902532 22 0.016
g protein coupled receptor signaling pathway GO:0007186 74 0.015
negative regulation of defense response GO:0031348 2 0.015
cognition GO:0050890 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
neuron projection extension GO:1990138 45 0.015
glial cell migration GO:0008347 3 0.015
cell morphogenesis GO:0000902 289 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
meiotic chromosome segregation GO:0045132 3 0.015
regulation of molecular function GO:0065009 70 0.015
regulation of protein metabolic process GO:0051246 56 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
positive regulation of stem cell proliferation GO:2000648 1 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of response to external stimulus GO:0032101 31 0.015
atp catabolic process GO:0006200 4 0.015
response to uv GO:0009411 3 0.015
sex determination GO:0007530 1 0.014
gastrulation GO:0007369 208 0.014
striated muscle tissue development GO:0014706 110 0.014
protein localization to nucleus GO:0034504 3 0.014
embryonic hemopoiesis GO:0035162 53 0.014
regulation of lipid transport GO:0032368 4 0.014
stem cell development GO:0048864 82 0.014
segmentation GO:0035282 97 0.014
regulation of locomotion GO:0040012 55 0.014
positive regulation of cytokine production GO:0001819 2 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
cellular response to hypoxia GO:0071456 1 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
response to endogenous stimulus GO:0009719 83 0.014
negative regulation of neuron projection regeneration GO:0070571 4 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
cell cycle arrest GO:0007050 1 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
response to inorganic substance GO:0010035 38 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
response to ketone GO:1901654 1 0.014
regulation of muscle contraction GO:0006937 3 0.013
positive regulation of blood circulation GO:1903524 2 0.013
cellular response to xenobiotic stimulus GO:0071466 35 0.013
endosomal transport GO:0016197 2 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
regulation of protein complex assembly GO:0043254 3 0.013
hemopoiesis GO:0030097 183 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
cellular response to oxygen levels GO:0071453 1 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.013
regulation of oxidative stress induced cell death GO:1903201 2 0.013
response to oxygen containing compound GO:1901700 55 0.013
mesoderm development GO:0007498 88 0.013
meiosis i GO:0007127 1 0.013
regulation of protein transport GO:0051223 3 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
glucose homeostasis GO:0042593 1 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
stem cell differentiation GO:0048863 117 0.012
response to oxygen levels GO:0070482 25 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
primary neural tube formation GO:0014020 1 0.012
cytokinesis GO:0000910 3 0.012
immune system process GO:0002376 241 0.012
actin mediated cell contraction GO:0070252 1 0.012
intracellular signal transduction GO:0035556 85 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
single organism biosynthetic process GO:0044711 71 0.012
regulation of neurogenesis GO:0050767 87 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of cell motility GO:2000145 46 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
ras protein signal transduction GO:0007265 7 0.012
regulation of jak stat cascade GO:0046425 3 0.012
developmental growth GO:0048589 166 0.012
cellular lipid metabolic process GO:0044255 36 0.012
developmental cell growth GO:0048588 52 0.012
locomotor rhythm GO:0045475 3 0.012
convergent extension GO:0060026 118 0.012
positive regulation of reproductive process GO:2000243 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
regulation of cytokine biosynthetic process GO:0042035 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
axon guidance GO:0007411 86 0.011
positive regulation of cell communication GO:0010647 56 0.011
cytokine metabolic process GO:0042107 1 0.011
paraxial mesoderm development GO:0048339 8 0.011
lipid homeostasis GO:0055088 3 0.011
single organism membrane fusion GO:0044801 2 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.011
protein targeting to nucleus GO:0044744 3 0.011
oocyte maturation GO:0001556 4 0.011
regulation of synapse organization GO:0050807 3 0.011
negative regulation of molecular function GO:0044092 23 0.011
carbohydrate homeostasis GO:0033500 1 0.011
phagocytosis GO:0006909 3 0.011
ion transmembrane transport GO:0034220 91 0.011
sensory perception of pain GO:0019233 1 0.011
response to decreased oxygen levels GO:0036293 25 0.011
regulation of embryonic development GO:0045995 47 0.011
phosphorylation GO:0016310 69 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
transmembrane transport GO:0055085 120 0.011
mechanosensory behavior GO:0007638 2 0.011
regulation of oocyte development GO:0060281 3 0.011
tissue homeostasis GO:0001894 25 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regulation of epidermis development GO:0045682 2 0.011
cell fate specification GO:0001708 68 0.011
lipid metabolic process GO:0006629 52 0.011
positive regulation of apoptotic process GO:0043065 29 0.011
taxis GO:0042330 109 0.011
liver development GO:0001889 96 0.011
multicellular organismal response to stress GO:0033555 2 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
gtp metabolic process GO:0046039 4 0.010
chemotaxis GO:0006935 104 0.010
collagen metabolic process GO:0032963 2 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
post embryonic organ development GO:0048569 4 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
regulation of response to stress GO:0080134 36 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
positive regulation of secretion GO:0051047 1 0.010
mitotic nuclear division GO:0007067 18 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
developmental growth involved in morphogenesis GO:0060560 86 0.010
somitogenesis GO:0001756 87 0.010

rasgef1bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.034
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.018