Danio rerio

0 known processes

sb:eu456

sb:eu456

sb:eu456 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.106
sensory organ development GO:0007423 393 0.105
generation of neurons GO:0048699 385 0.067
eye development GO:0001654 277 0.063
regulation of signaling GO:0023051 235 0.063
larval development GO:0002164 2 0.060
central nervous system development GO:0007417 387 0.060
neuron differentiation GO:0030182 353 0.054
eye morphogenesis GO:0048592 144 0.053
aging GO:0007568 2 0.053
embryonic organ development GO:0048568 381 0.050
response to chemical GO:0042221 320 0.048
sensory organ morphogenesis GO:0090596 200 0.048
regulation of macromolecule metabolic process GO:0060255 317 0.047
camera type eye development GO:0043010 222 0.047
regulation of multicellular organismal process GO:0051239 277 0.045
cell surface receptor signaling pathway GO:0007166 325 0.043
nitrogen compound metabolic process GO:0006807 319 0.043
nucleic acid metabolic process GO:0090304 244 0.043
multicellular organism growth GO:0035264 4 0.042
cellular macromolecule biosynthetic process GO:0034645 224 0.041
regulation of multicellular organism growth GO:0040014 4 0.040
cell morphogenesis involved in differentiation GO:0000904 195 0.040
gene expression GO:0010467 252 0.040
signal transduction GO:0007165 455 0.039
response to stress GO:0006950 263 0.038
vasculature development GO:0001944 278 0.038
single organism metabolic process GO:0044710 217 0.037
regulation of metabolic process GO:0019222 359 0.037
regulation of biosynthetic process GO:0009889 250 0.037
regulation of multicellular organismal development GO:2000026 223 0.036
protein modification process GO:0036211 100 0.036
macromolecule biosynthetic process GO:0009059 227 0.035
cell motility GO:0048870 244 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
regulation of cell communication GO:0010646 232 0.034
regulation of gene expression GO:0010468 265 0.033
head development GO:0060322 303 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
positive regulation of transport GO:0051050 2 0.032
digestive system development GO:0055123 289 0.031
response to uv GO:0009411 3 0.031
tube morphogenesis GO:0035239 349 0.031
meiotic nuclear division GO:0007126 4 0.031
regulation of signal transduction GO:0009966 225 0.031
neuron development GO:0048666 262 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
cell part morphogenesis GO:0032990 246 0.030
regulation of developmental process GO:0050793 247 0.030
organic substance biosynthetic process GO:1901576 289 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
axonogenesis GO:0007409 152 0.028
regulation of cytokine production GO:0001817 3 0.028
cell projection morphogenesis GO:0048858 244 0.028
cell projection organization GO:0030030 284 0.028
camera type eye morphogenesis GO:0048593 108 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
cellular protein metabolic process GO:0044267 129 0.027
negative regulation of biological process GO:0048519 304 0.026
embryonic heart tube development GO:0035050 133 0.026
positive regulation of cell cycle GO:0045787 3 0.026
cellular component morphogenesis GO:0032989 336 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
biosynthetic process GO:0009058 294 0.026
cellular response to external stimulus GO:0071496 2 0.026
epithelial tube morphogenesis GO:0060562 148 0.025
heterocycle metabolic process GO:0046483 290 0.025
regulation of biological quality GO:0065008 263 0.025
blood vessel development GO:0001568 246 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
inner ear development GO:0048839 126 0.025
regulation of reproductive process GO:2000241 4 0.025
retina development in camera type eye GO:0060041 146 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
female sex differentiation GO:0046660 4 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
enzyme linked receptor protein signaling pathway GO:0007167 106 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
transcription dna templated GO:0006351 181 0.024
response to monosaccharide GO:0034284 3 0.024
response to external stimulus GO:0009605 264 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
cellular biosynthetic process GO:0044249 286 0.024
phagocytosis GO:0006909 3 0.024
maintenance of location GO:0051235 4 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
somatic muscle development GO:0007525 4 0.024
cell substrate adhesion GO:0031589 4 0.023
positive regulation of biological process GO:0048518 253 0.023
positive regulation of map kinase activity GO:0043406 3 0.023
stem cell maintenance GO:0019827 4 0.023
immune system process GO:0002376 241 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
positive regulation of cellular process GO:0048522 201 0.023
mononuclear cell proliferation GO:0032943 1 0.023
leukocyte proliferation GO:0070661 1 0.022
brain development GO:0007420 293 0.022
specification of symmetry GO:0009799 204 0.022
positive regulation of immune effector process GO:0002699 3 0.022
negative chemotaxis GO:0050919 1 0.022
blood vessel morphogenesis GO:0048514 216 0.022
heart development GO:0007507 313 0.022
muscle cell differentiation GO:0042692 139 0.021
regulation of response to stimulus GO:0048583 269 0.021
lipid catabolic process GO:0016042 4 0.021
ameboidal type cell migration GO:0001667 143 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
cellular protein modification process GO:0006464 100 0.021
regulation of cell activation GO:0050865 1 0.021
stem cell proliferation GO:0072089 4 0.021
cell fate commitment GO:0045165 99 0.021
determination of left right symmetry GO:0007368 179 0.021
cell morphogenesis GO:0000902 289 0.021
skeletal system development GO:0001501 181 0.021
rna biosynthetic process GO:0032774 181 0.021
axon development GO:0061564 166 0.021
macromolecule modification GO:0043412 111 0.021
positive regulation of cell activation GO:0050867 1 0.021
regulation of mrna processing GO:0050684 3 0.021
tissue remodeling GO:0048771 4 0.020
regulation of cell differentiation GO:0045595 142 0.020
neuron projection development GO:0031175 180 0.020
regionalization GO:0003002 274 0.020
renal system development GO:0072001 94 0.020
rna metabolic process GO:0016070 219 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
protein metabolic process GO:0019538 183 0.020
compound eye development GO:0048749 2 0.020
post embryonic organ development GO:0048569 4 0.020
regulation of protein transport GO:0051223 3 0.020
cellular component movement GO:0006928 335 0.020
retina morphogenesis in camera type eye GO:0060042 79 0.020
developmental growth involved in morphogenesis GO:0060560 86 0.019
chordate embryonic development GO:0043009 271 0.019
angiogenesis GO:0001525 158 0.019
establishment of localization GO:0051234 244 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.018
response to glucose GO:0009749 3 0.018
lymphocyte proliferation GO:0046651 1 0.018
regulation of primary metabolic process GO:0080090 311 0.018
nuclear transport GO:0051169 4 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
hemopoiesis GO:0030097 183 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
cell migration GO:0016477 237 0.018
locomotion GO:0040011 313 0.018
connective tissue development GO:0061448 99 0.018
localization of cell GO:0051674 244 0.018
digestive tract morphogenesis GO:0048546 231 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
dorsal ventral pattern formation GO:0009953 125 0.017
spermatid differentiation GO:0048515 2 0.017
system process GO:0003008 185 0.017
digestive tract development GO:0048565 265 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
spermatid development GO:0007286 2 0.017
response to carbohydrate GO:0009743 3 0.017
protein import into nucleus GO:0006606 3 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
oxoacid metabolic process GO:0043436 31 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.016
regulation of rna metabolic process GO:0051252 224 0.016
protein import GO:0017038 3 0.016
oocyte maturation GO:0001556 4 0.016
autophagy GO:0006914 4 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
neuron projection extension GO:1990138 45 0.016
developmental cell growth GO:0048588 52 0.016
response to wounding GO:0009611 116 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
developmental growth GO:0048589 166 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
mitochondrion organization GO:0007005 4 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
b cell activation GO:0042113 2 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
positive regulation of cytokine production GO:0001819 2 0.015
neuron projection morphogenesis GO:0048812 161 0.015
response to external biotic stimulus GO:0043207 97 0.015
pectoral fin development GO:0033339 50 0.015
response to drug GO:0042493 3 0.015
fin development GO:0033333 77 0.015
transport GO:0006810 220 0.015
axon extension GO:0048675 45 0.015
female gonad development GO:0008585 4 0.015
forebrain development GO:0030900 96 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to organic substance GO:0071310 105 0.015
wound healing GO:0042060 90 0.015
mesoderm development GO:0007498 88 0.015
otic vesicle development GO:0071599 42 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
chemosensory behavior GO:0007635 1 0.015
cellular component assembly GO:0022607 170 0.015
organic acid metabolic process GO:0006082 31 0.015
gtp catabolic process GO:0006184 2 0.014
multi organism cellular process GO:0044764 2 0.014
cognition GO:0050890 1 0.014
amine metabolic process GO:0009308 2 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
multi organism process GO:0051704 134 0.014
determination of bilateral symmetry GO:0009855 204 0.014
lipid storage GO:0019915 1 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
negative regulation of cellular process GO:0048523 283 0.014
cell death GO:0008219 121 0.014
nucleic acid templated transcription GO:0097659 181 0.014
regulation of cell development GO:0060284 100 0.014
phosphorylation GO:0016310 69 0.014
protein targeting to nucleus GO:0044744 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of cell projection assembly GO:0060491 4 0.013
response to growth factor GO:0070848 39 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
kidney development GO:0001822 92 0.013
phosphorus metabolic process GO:0006793 109 0.013
response to hexose GO:0009746 3 0.013
organelle organization GO:0006996 227 0.013
immune system development GO:0002520 191 0.013
regulation of protein targeting GO:1903533 2 0.013
phagocytosis engulfment GO:0006911 1 0.013
nuclear import GO:0051170 3 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
growth GO:0040007 174 0.013
gtp metabolic process GO:0046039 4 0.013
cellular component biogenesis GO:0044085 178 0.013
axon guidance GO:0007411 86 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
protein dephosphorylation GO:0006470 3 0.013
membrane invagination GO:0010324 1 0.013
regulation of wound healing GO:0061041 2 0.013
cell proliferation GO:0008283 80 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
convergent extension GO:0060026 118 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of cell shape GO:0008360 1 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
negative regulation of cytokine production GO:0001818 1 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
urogenital system development GO:0001655 97 0.012
regulation of inflammatory response GO:0050727 2 0.012
mesenchymal cell development GO:0014031 78 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of blood pressure GO:0008217 1 0.012
ear development GO:0043583 127 0.012
regulation of synapse organization GO:0050807 3 0.012
positive regulation of ras protein signal transduction GO:0046579 1 0.012
epithelial cell differentiation GO:0030855 116 0.012
secondary metabolic process GO:0019748 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
neuron projection guidance GO:0097485 86 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
small molecule metabolic process GO:0044281 77 0.012
response to biotic stimulus GO:0009607 97 0.012
protein localization to nucleus GO:0034504 3 0.012
pronephros development GO:0048793 69 0.012
single organism nuclear import GO:1902593 3 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
meiotic cell cycle process GO:1903046 3 0.012
gland development GO:0048732 143 0.012
regulation of protein complex assembly GO:0043254 3 0.012
taxis GO:0042330 109 0.012
chemotaxis GO:0006935 104 0.012
cartilage development GO:0051216 96 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
peptidyl serine modification GO:0018209 2 0.012
neuroblast proliferation GO:0007405 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
positive regulation of translation GO:0045727 1 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
sprouting angiogenesis GO:0002040 53 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of protein catabolic process GO:0042176 1 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of localization GO:0032879 104 0.011
single organism localization GO:1902578 225 0.011
defense response GO:0006952 47 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
behavior GO:0007610 74 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
single organism biosynthetic process GO:0044711 71 0.011
apoptotic process GO:0006915 116 0.011
lateral inhibition GO:0046331 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
adherens junction organization GO:0034332 4 0.011
liver development GO:0001889 96 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
cellular lipid catabolic process GO:0044242 3 0.011
positive regulation of gene expression GO:0010628 71 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.010
death GO:0016265 121 0.010
cellular protein catabolic process GO:0044257 4 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
defense response to other organism GO:0098542 33 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
astrocyte differentiation GO:0048708 1 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
regulation of binding GO:0051098 3 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
gastrulation GO:0007369 208 0.010
negative regulation of signaling GO:0023057 96 0.010
ras protein signal transduction GO:0007265 7 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
regulation of transcription dna templated GO:0006355 213 0.010
regulation of myotube differentiation GO:0010830 2 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
hormone secretion GO:0046879 2 0.010
hepaticobiliary system development GO:0061008 98 0.010

sb:eu456 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.020
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
nervous system disease DOID:863 0 0.019
organ system cancer DOID:0050686 0 0.014