Danio rerio

148 known processes

tbx16

T-box gene 16

(Aliases: zgc:109817,spt,wu:fa17g07,spt-1,cb103,id:ibd2185)

tbx16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart jogging GO:0003146 40 0.999
regionalization GO:0003002 274 0.999
pericardium morphogenesis GO:0003344 1 0.998
Zebrafish
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.996
specification of organ position GO:0010159 3 0.995
Zebrafish
bmp signaling pathway involved in heart development GO:0061312 15 0.995
organic cyclic compound biosynthetic process GO:1901362 223 0.995
Zebrafish
somitogenesis GO:0001756 87 0.993
brain development GO:0007420 293 0.991
Zebrafish
segmentation GO:0035282 97 0.991
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.989
positive regulation of biological process GO:0048518 253 0.988
Zebrafish
somite specification GO:0001757 12 0.988
determination of left right symmetry GO:0007368 179 0.988
hematopoietic stem cell differentiation GO:0060218 20 0.987
bmp signaling pathway involved in heart jogging GO:0003303 14 0.984
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.981
Zebrafish
cell fate commitment GO:0045165 99 0.979
Zebrafish
specification of symmetry GO:0009799 204 0.979
signal transduction GO:0007165 455 0.978
heart development GO:0007507 313 0.977
digestive tract development GO:0048565 265 0.975
axial mesoderm formation GO:0048320 4 0.975
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.975
dorsal ventral pattern formation GO:0009953 125 0.975
Zebrafish
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.974
regulation of cellular metabolic process GO:0031323 320 0.973
negative regulation of cellular process GO:0048523 283 0.972
Zebrafish
regulation of metabolic process GO:0019222 359 0.969
cell differentiation in spinal cord GO:0021515 40 0.960
Zebrafish
convergent extension GO:0060026 118 0.958
Zebrafish
formation of primary germ layer GO:0001704 62 0.957
Zebrafish
central nervous system development GO:0007417 387 0.955
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.955
atrioventricular valve formation GO:0003190 3 0.952
Zebrafish
proepicardium development GO:0003342 4 0.951
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.946
diencephalon development GO:0021536 58 0.945
Zebrafish
intermediate mesoderm development GO:0048389 2 0.941
negative regulation of multicellular organismal process GO:0051241 69 0.939
mesoderm formation GO:0001707 43 0.938
Zebrafish
morphogenesis of an epithelial sheet GO:0002011 49 0.938
Zebrafish
embryonic pattern specification GO:0009880 44 0.929
head development GO:0060322 303 0.928
Zebrafish
cell proliferation involved in heart morphogenesis GO:0061323 2 0.928
Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.928
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.926
embryonic organ development GO:0048568 381 0.925
heart morphogenesis GO:0003007 156 0.923
pericardium development GO:0060039 1 0.923
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.919
Zebrafish
cell motility GO:0048870 244 0.918
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.918
neural tube development GO:0021915 62 0.916
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.913
bmp signaling pathway GO:0030509 52 0.909
gastrulation GO:0007369 208 0.909
negative regulation of developmental process GO:0051093 65 0.908
anterior posterior pattern specification GO:0009952 152 0.906
regulation of multicellular organismal development GO:2000026 223 0.903
convergent extension involved in gastrulation GO:0060027 71 0.900
regulation of rna biosynthetic process GO:2001141 213 0.899
heart field specification GO:0003128 1 0.899
nucleic acid templated transcription GO:0097659 181 0.897
Zebrafish
arterial endothelial cell differentiation GO:0060842 2 0.893
tube morphogenesis GO:0035239 349 0.890
regulation of heart morphogenesis GO:2000826 17 0.886
immune system process GO:0002376 241 0.881
rna biosynthetic process GO:0032774 181 0.878
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.877
blood vessel morphogenesis GO:0048514 216 0.865
retinal rod cell development GO:0046548 4 0.861
Zebrafish
mesendoderm development GO:0048382 10 0.854
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.853
Zebrafish
embryonic heart tube development GO:0035050 133 0.851
somite development GO:0061053 96 0.850
determination of left right asymmetry in nervous system GO:0035545 4 0.847
regulation of macromolecule biosynthetic process GO:0010556 225 0.831
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.823
endodermal cell fate specification GO:0001714 17 0.821
Zebrafish
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.811
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.806
hematopoietic or lymphoid organ development GO:0048534 191 0.799
morphogenesis of an epithelium GO:0002009 333 0.797
negative regulation of biological process GO:0048519 304 0.790
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.789
digestive system development GO:0055123 289 0.781
determination of heart left right asymmetry GO:0061371 117 0.776
notochord morphogenesis GO:0048570 17 0.773
localization of cell GO:0051674 244 0.769
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.768
Zebrafish
determination of left right asymmetry in diencephalon GO:0035462 4 0.765
notochord cell differentiation GO:0060034 18 0.762
Zebrafish
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.751
cell surface receptor signaling pathway GO:0007166 325 0.750
pronephros morphogenesis GO:0072114 14 0.747
lateral mesoderm development GO:0048368 23 0.744
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.741
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.740
retinal cone cell development GO:0046549 8 0.738
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.735
Zebrafish
regulation of cell communication GO:0010646 232 0.734
cellular component morphogenesis GO:0032989 336 0.730
negative regulation of cell differentiation GO:0045596 46 0.721
regulation of nucleic acid templated transcription GO:1903506 213 0.706
vasculogenesis GO:0001570 41 0.704
enzyme linked receptor protein signaling pathway GO:0007167 106 0.703
endodermal cell differentiation GO:0035987 19 0.699
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.694
embryonic heart tube morphogenesis GO:0003143 108 0.686
stem cell differentiation GO:0048863 117 0.685
organ formation GO:0048645 17 0.685
Zebrafish
floor plate morphogenesis GO:0033505 12 0.683
stem cell development GO:0048864 82 0.683
photoreceptor cell fate commitment GO:0046552 1 0.680
Zebrafish
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.664
determination of dorsal identity GO:0048263 13 0.663
Zebrafish
angiogenesis GO:0001525 158 0.661
pancreas development GO:0031016 84 0.660
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.652
septum transversum development GO:0003343 4 0.651
Zebrafish
inner ear morphogenesis GO:0042472 63 0.651
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.650
embryonic organ morphogenesis GO:0048562 274 0.647
striated muscle tissue development GO:0014706 110 0.646
Zebrafish
regulation of response to stimulus GO:0048583 269 0.644
cardiac atrium morphogenesis GO:0003209 2 0.642
regulation of signal transduction GO:0009966 225 0.635
cell migration involved in gastrulation GO:0042074 79 0.631
Zebrafish
chordate embryonic development GO:0043009 271 0.630
endoderm development GO:0007492 49 0.629
Zebrafish
aorta morphogenesis GO:0035909 3 0.629
camera type eye photoreceptor cell differentiation GO:0060219 19 0.615
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.609
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.608
Zebrafish
positive regulation of stem cell proliferation GO:2000648 1 0.602
mesoderm morphogenesis GO:0048332 51 0.591
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.579
Zebrafish
axial mesodermal cell fate specification GO:0048327 3 0.577
nephron tubule morphogenesis GO:0072078 1 0.572
regulation of embryonic development GO:0045995 47 0.566
cellular component movement GO:0006928 335 0.564
Zebrafish
regulation of mesodermal cell fate specification GO:0042661 9 0.563
mesoderm development GO:0007498 88 0.563
positive regulation of gene expression GO:0010628 71 0.554
Zebrafish
atrioventricular valve development GO:0003171 11 0.529
Zebrafish
negative regulation of cell development GO:0010721 26 0.527
appendage morphogenesis GO:0035107 56 0.526
Zebrafish
morphogenesis of an epithelial fold GO:0060571 1 0.520
Zebrafish
connective tissue development GO:0061448 99 0.515
Zebrafish
regulation of developmental process GO:0050793 247 0.504
positive regulation of signaling GO:0023056 56 0.492
neuron fate specification GO:0048665 20 0.490
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.490
embryo development ending in birth or egg hatching GO:0009792 271 0.488
blood vessel endothelial cell differentiation GO:0060837 2 0.477
hemopoiesis GO:0030097 183 0.475
regulation of signaling GO:0023051 235 0.471
endodermal cell fate commitment GO:0001711 18 0.465
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.463
floor plate formation GO:0021508 12 0.454
camera type eye development GO:0043010 222 0.446
Zebrafish
positive regulation of response to stimulus GO:0048584 80 0.437
positive regulation of cellular biosynthetic process GO:0031328 68 0.436
Zebrafish
cell migration GO:0016477 237 0.435
Zebrafish
endocardium morphogenesis GO:0003160 4 0.432
negative regulation of cell communication GO:0010648 96 0.432
positive regulation of rna biosynthetic process GO:1902680 57 0.426
Zebrafish
ameboidal type cell migration GO:0001667 143 0.423
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.422
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.422
Zebrafish
cellular biosynthetic process GO:0044249 286 0.421
Zebrafish
heart valve morphogenesis GO:0003179 8 0.419
Zebrafish
rna metabolic process GO:0016070 219 0.415
Zebrafish
regulation of cell motility GO:2000145 46 0.404
mesodermal cell differentiation GO:0048333 21 0.403
kidney development GO:0001822 92 0.403
negative regulation of mesodermal cell fate specification GO:0042662 3 0.402
forebrain development GO:0030900 96 0.401
Zebrafish
rostrocaudal neural tube patterning GO:0021903 29 0.399
endocardium development GO:0003157 9 0.396
erythrocyte differentiation GO:0030218 54 0.394
immune system development GO:0002520 191 0.392
regulation of cell proliferation GO:0042127 37 0.391
Zebrafish
renal system development GO:0072001 94 0.380
aorta development GO:0035904 4 0.379
heart valve formation GO:0003188 4 0.378
Zebrafish
regulation of mesoderm development GO:2000380 11 0.369
heterocycle metabolic process GO:0046483 290 0.367
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.360
kidney epithelium development GO:0072073 23 0.357
protein metabolic process GO:0019538 183 0.353
nephron epithelium morphogenesis GO:0072088 1 0.348
limb bud formation GO:0060174 2 0.347
Zebrafish
semicircular canal morphogenesis GO:0048752 18 0.347
Zebrafish
cardiac atrium development GO:0003230 4 0.345
muscle structure development GO:0061061 196 0.340
cellular macromolecule metabolic process GO:0044260 391 0.339
Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.338
sexual reproduction GO:0019953 36 0.336
notochord formation GO:0014028 6 0.335
ventral spinal cord development GO:0021517 35 0.335
Zebrafish
nephric duct morphogenesis GO:0072178 7 0.333
neuron projection development GO:0031175 180 0.333
cellular aromatic compound metabolic process GO:0006725 295 0.332
Zebrafish
locomotion GO:0040011 313 0.325
Zebrafish
notochord development GO:0030903 54 0.325
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.321
neural tube patterning GO:0021532 33 0.319
negative regulation of signal transduction GO:0009968 94 0.318
negative regulation of response to stimulus GO:0048585 104 0.317
somatic motor neuron differentiation GO:0021523 5 0.315
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.308
Zebrafish
pectoral fin development GO:0033339 50 0.300
Zebrafish
eye development GO:0001654 277 0.295
Zebrafish
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.293
regeneration GO:0031099 91 0.291
regulation of system process GO:0044057 40 0.289
Zebrafish
somite rostral caudal axis specification GO:0032525 5 0.284
embryonic pectoral fin morphogenesis GO:0035118 24 0.281
Zebrafish
cell projection morphogenesis GO:0048858 244 0.280
central nervous system neuron differentiation GO:0021953 74 0.279
Zebrafish
regulation of bmp signaling pathway GO:0030510 39 0.275
positive regulation of macromolecule metabolic process GO:0010604 93 0.275
Zebrafish
embryonic heart tube left right pattern formation GO:0060971 5 0.274
regulation of cellular biosynthetic process GO:0031326 245 0.269
axon development GO:0061564 166 0.269
regulation of transcription dna templated GO:0006355 213 0.269
nucleobase containing compound biosynthetic process GO:0034654 205 0.268
Zebrafish
negative regulation of gene expression GO:0010629 65 0.266
Zebrafish
optic nerve development GO:0021554 15 0.264
Zebrafish
neural crest cell differentiation GO:0014033 72 0.258
Zebrafish
midbrain hindbrain boundary development GO:0030917 23 0.251
notch signaling pathway GO:0007219 35 0.251
positive regulation of metabolic process GO:0009893 108 0.251
Zebrafish
embryonic appendage morphogenesis GO:0035113 30 0.249
Zebrafish
ear morphogenesis GO:0042471 64 0.249
Zebrafish
regulation of cell death GO:0010941 103 0.247
embryonic hemopoiesis GO:0035162 53 0.246
Zebrafish
convergent extension involved in organogenesis GO:0060029 10 0.243
embryonic camera type eye development GO:0031076 29 0.243
segment specification GO:0007379 12 0.243
regulation of canonical wnt signaling pathway GO:0060828 34 0.240
tissue remodeling GO:0048771 4 0.238
Zebrafish
developmental maturation GO:0021700 34 0.237
striated muscle cell differentiation GO:0051146 129 0.235
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.234
Zebrafish
blood vessel development GO:0001568 246 0.232
urogenital system development GO:0001655 97 0.231
positive regulation of cell proliferation GO:0008284 15 0.229
Zebrafish
pronephric duct morphogenesis GO:0039023 7 0.227
cellular nitrogen compound metabolic process GO:0034641 290 0.226
Zebrafish
hepatocyte differentiation GO:0070365 1 0.222
anterior posterior axis specification GO:0009948 20 0.221
anterior posterior axis specification embryo GO:0008595 5 0.221
cell proliferation GO:0008283 80 0.220
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.219
Zebrafish
cell cycle GO:0007049 93 0.217
endocardial cushion formation GO:0003272 2 0.216
positive regulation of cell cycle GO:0045787 3 0.216
cellular component biogenesis GO:0044085 178 0.214
embryonic foregut morphogenesis GO:0048617 1 0.213
germ cell development GO:0007281 22 0.211
cellular response to stress GO:0033554 62 0.211
endocardial cell differentiation GO:0060956 5 0.209
metencephalon development GO:0022037 27 0.209
endoderm formation GO:0001706 29 0.209
Zebrafish
outflow tract morphogenesis GO:0003151 1 0.207
wnt signaling pathway involved in heart development GO:0003306 5 0.207
muscle cell differentiation GO:0042692 139 0.205
Zebrafish
stem cell maintenance GO:0019827 4 0.204
gene expression GO:0010467 252 0.204
Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.203
embryonic axis specification GO:0000578 12 0.203
camera type eye morphogenesis GO:0048593 108 0.201
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.196
Zebrafish
hematopoietic progenitor cell differentiation GO:0002244 23 0.194
segment polarity determination GO:0007367 1 0.193
cartilage development GO:0051216 96 0.192
Zebrafish
cytoskeleton organization GO:0007010 96 0.191
atrial ventricular junction remodeling GO:0003294 2 0.190
Zebrafish
cardiogenic plate morphogenesis GO:0003142 1 0.189
heart valve development GO:0003170 14 0.188
Zebrafish
cardiac conduction system development GO:0003161 1 0.186
cilium morphogenesis GO:0060271 85 0.185
cell migration in hindbrain GO:0021535 7 0.183
regulation of gene expression GO:0010468 265 0.183
regulation of cartilage development GO:0061035 7 0.182
regulation of glial cell differentiation GO:0045685 4 0.181
gliogenesis GO:0042063 45 0.179
appendage development GO:0048736 80 0.177
Zebrafish
regulation of nervous system development GO:0051960 90 0.175
positive regulation of neural precursor cell proliferation GO:2000179 1 0.175
regulation of multicellular organismal process GO:0051239 277 0.174
cellular nitrogen compound biosynthetic process GO:0044271 218 0.173
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.173
Zebrafish
response to external stimulus GO:0009605 264 0.172
regulation of cell differentiation GO:0045595 142 0.171
gall bladder development GO:0061010 1 0.170
somatic muscle development GO:0007525 4 0.169
cell fate specification GO:0001708 68 0.167
Zebrafish
response to chemical GO:0042221 320 0.166
cardiac chamber development GO:0003205 19 0.165
Zebrafish
response to lipid GO:0033993 60 0.163
astrocyte differentiation GO:0048708 1 0.161
oocyte maturation GO:0001556 4 0.159
regulation of neural precursor cell proliferation GO:2000177 3 0.159
inner ear development GO:0048839 126 0.157
Zebrafish
single organism organelle organization GO:1902589 199 0.157
neuron development GO:0048666 262 0.157
Zebrafish
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.156
kidney morphogenesis GO:0060993 15 0.154
tissue migration GO:0090130 37 0.154
chemotaxis GO:0006935 104 0.154
cell maturation GO:0048469 23 0.153
eye morphogenesis GO:0048592 144 0.151
Zebrafish
regulation of endodermal cell differentiation GO:1903224 15 0.150
organic cyclic compound metabolic process GO:1901360 301 0.149
Zebrafish
ear development GO:0043583 127 0.149
Zebrafish
paraxial mesoderm development GO:0048339 8 0.147
compound eye development GO:0048749 2 0.146
thalamus development GO:0021794 6 0.142
cell morphogenesis GO:0000902 289 0.142
limb morphogenesis GO:0035108 7 0.140
Zebrafish
pronephros development GO:0048793 69 0.140
positive regulation of biosynthetic process GO:0009891 68 0.138
Zebrafish
biosynthetic process GO:0009058 294 0.136
Zebrafish
fin morphogenesis GO:0033334 53 0.136
Zebrafish
organelle organization GO:0006996 227 0.135
facial nucleus development GO:0021754 7 0.135
protein import into nucleus GO:0006606 3 0.131
transcription dna templated GO:0006351 181 0.130
Zebrafish
primary neural tube formation GO:0014020 1 0.130
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.128
oocyte development GO:0048599 14 0.128
nephron morphogenesis GO:0072028 2 0.128
stem cell proliferation GO:0072089 4 0.127
epithalamus development GO:0021538 10 0.127
Zebrafish
heart looping GO:0001947 94 0.126
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.125
diencephalon morphogenesis GO:0048852 5 0.125
negative regulation of nucleic acid templated transcription GO:1903507 45 0.123
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.121
vasculature development GO:0001944 278 0.120
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.120
embryonic limb morphogenesis GO:0030326 2 0.117
heart formation GO:0060914 13 0.117
Zebrafish
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.116
sensory organ morphogenesis GO:0090596 200 0.115
Zebrafish
mesodermal cell fate commitment GO:0001710 14 0.115
axis elongation GO:0003401 31 0.113
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.112
neural crest cell development GO:0014032 62 0.112
Zebrafish
neuroblast proliferation GO:0007405 2 0.112
negative regulation of wnt signaling pathway GO:0030178 30 0.111
regulation of cytoplasmic transport GO:1903649 4 0.111
negative regulation of signaling GO:0023057 96 0.109
embryonic digestive tract morphogenesis GO:0048557 3 0.109
rhombomere formation GO:0021594 12 0.108
regulation of heart contraction GO:0008016 32 0.107
Zebrafish
single organism localization GO:1902578 225 0.107
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.107
Zebrafish
regulation of inner ear receptor cell differentiation GO:2000980 1 0.106
positive regulation of nucleic acid templated transcription GO:1903508 57 0.105
Zebrafish
commissural neuron axon guidance GO:0071679 3 0.105
negative regulation of rna biosynthetic process GO:1902679 45 0.104
Zebrafish
semicircular canal development GO:0060872 24 0.104
Zebrafish
hepatic duct development GO:0061011 2 0.101
regulation of apoptotic process GO:0042981 98 0.101
embryonic eye morphogenesis GO:0048048 30 0.101
hindbrain development GO:0030902 91 0.101
motor neuron axon guidance GO:0008045 23 0.101
endothelium development GO:0003158 25 0.100
specification of axis polarity GO:0065001 4 0.099
homeostasis of number of cells GO:0048872 62 0.099
rhombomere morphogenesis GO:0021593 17 0.098
rhombomere development GO:0021546 19 0.097
cilium organization GO:0044782 71 0.097
protein modification process GO:0036211 100 0.097
regulation of cellular component organization GO:0051128 86 0.096
proteasomal protein catabolic process GO:0010498 2 0.096
forebrain dorsal ventral pattern formation GO:0021798 1 0.095
system process GO:0003008 185 0.094
Zebrafish
regulation of cell cycle GO:0051726 52 0.094
mitotic nuclear division GO:0007067 18 0.094
stem cell fate commitment GO:0048865 1 0.094
regulation of synapse assembly GO:0051963 3 0.093
blastoderm segmentation GO:0007350 6 0.092
cell part morphogenesis GO:0032990 246 0.092
axis specification GO:0009798 43 0.090
retina layer formation GO:0010842 24 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.088
Zebrafish
cell fate commitment involved in pattern specification GO:0060581 6 0.088
optic placode formation involved in camera type eye formation GO:0046619 3 0.088
negative regulation of oocyte development GO:0060283 2 0.087
response to endogenous stimulus GO:0009719 83 0.087
generation of neurons GO:0048699 385 0.087
Zebrafish
photoreceptor cell development GO:0042461 40 0.087
Zebrafish
positive regulation of cellular process GO:0048522 201 0.086
Zebrafish
hindbrain morphogenesis GO:0021575 22 0.085
cardiac endothelial cell differentiation GO:0003348 5 0.085
regulation of anterior head development GO:2000742 2 0.085
post anal tail morphogenesis GO:0036342 19 0.083
Zebrafish
endocardial cushion morphogenesis GO:0003203 3 0.083
establishment of localization GO:0051234 244 0.082
germ line stem cell division GO:0042078 1 0.082
cellular component assembly GO:0022607 170 0.080
pectoral fin morphogenesis GO:0035138 29 0.079
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.079
Zebrafish
ventral spinal cord interneuron specification GO:0021521 3 0.078
regulation of growth GO:0040008 42 0.078
apoptotic process GO:0006915 116 0.077
negative regulation of cell fate specification GO:0009996 11 0.077
dorsal convergence GO:0060030 14 0.075
multi organism process GO:0051704 134 0.075
regulation of locomotion GO:0040012 55 0.075
regulation of notch signaling pathway GO:0008593 16 0.074
response to biotic stimulus GO:0009607 97 0.074
regulation of wnt signaling pathway GO:0030111 53 0.073
endothelial cell fate commitment GO:0060839 3 0.072
specification of organ identity GO:0010092 2 0.072
single organism transport GO:0044765 206 0.071
rhombomere 4 development GO:0021570 5 0.071
nitrogen compound metabolic process GO:0006807 319 0.071
Zebrafish
cranial nerve development GO:0021545 42 0.071
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.071
positive regulation of map kinase activity GO:0043406 3 0.070
negative regulation of macromolecule metabolic process GO:0010605 76 0.070
Zebrafish
regulation of synapse organization GO:0050807 3 0.070
epithelial tube formation GO:0072175 19 0.069
dorsal aorta morphogenesis GO:0035912 3 0.069
pons development GO:0021548 11 0.069
meiotic nuclear division GO:0007126 4 0.069
muscle fiber development GO:0048747 52 0.068
mitotic cell cycle GO:0000278 64 0.068
response to organic substance GO:0010033 153 0.068
negative regulation of nervous system development GO:0051961 22 0.067
wnt signaling pathway GO:0016055 80 0.067
pharyngeal muscle development GO:0043282 4 0.067
Zebrafish
stem cell division GO:0017145 1 0.067
telencephalon development GO:0021537 14 0.066
transport GO:0006810 220 0.066
pharynx development GO:0060465 5 0.066
Zebrafish
mesenchyme morphogenesis GO:0072132 5 0.065
sensory organ development GO:0007423 393 0.065
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.064
g1 s transition of mitotic cell cycle GO:0000082 1 0.064
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.064
positive regulation of rna metabolic process GO:0051254 59 0.063
Zebrafish
endocardium formation GO:0060214 1 0.063
artery development GO:0060840 22 0.063
regulation of reproductive process GO:2000241 4 0.062
tube closure GO:0060606 1 0.062
cardiac chamber formation GO:0003207 4 0.062
regulation of biological quality GO:0065008 263 0.061
bone morphogenesis GO:0060349 11 0.061
cardiac chamber morphogenesis GO:0003206 12 0.061
positive regulation of stress activated mapk cascade GO:0032874 3 0.061
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.060
positive regulation of skeletal muscle tissue development GO:0048643 1 0.059
cellular protein metabolic process GO:0044267 129 0.058
immune effector process GO:0002252 23 0.058
endodermal cell fate determination GO:0007493 2 0.058
protein maturation GO:0051604 12 0.058
cellular response to organic substance GO:0071310 105 0.057
regulation of macromolecule metabolic process GO:0060255 317 0.057
spinal cord development GO:0021510 46 0.057
Zebrafish
oocyte differentiation GO:0009994 14 0.057
gastrulation with mouth forming second GO:0001702 44 0.057
Zebrafish
neuron fate commitment GO:0048663 26 0.057
Zebrafish
dorsal ventral axis specification GO:0009950 14 0.056
spemann organizer formation at the embryonic shield GO:0060063 2 0.056
developmental growth involved in morphogenesis GO:0060560 86 0.056
Zebrafish
foregut morphogenesis GO:0007440 4 0.056
nucleocytoplasmic transport GO:0006913 4 0.055
response to oxygen containing compound GO:1901700 55 0.055
regulation of blood circulation GO:1903522 32 0.055
Zebrafish
organic substance transport GO:0071702 58 0.055
cell cell signaling GO:0007267 52 0.054
heart process GO:0003015 71 0.054
Zebrafish
macromolecular complex subunit organization GO:0043933 74 0.054
negative regulation of endodermal cell differentiation GO:1903225 8 0.053
phosphorylation GO:0016310 69 0.053
cardiac cell fate commitment GO:0060911 1 0.053
muscle organ development GO:0007517 101 0.053
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.052
metal ion transport GO:0030001 58 0.052
gamete generation GO:0007276 33 0.052
nephron development GO:0072006 31 0.052
neural precursor cell proliferation GO:0061351 20 0.052
negative regulation of myeloid cell differentiation GO:0045638 1 0.051
positive regulation of synapse assembly GO:0051965 1 0.051
heart rudiment formation GO:0003315 5 0.050

tbx16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.651
dysostosis DOID:1934 0 0.651
bone disease DOID:0080001 0 0.651
bone development disease DOID:0080006 0 0.651
disease of anatomical entity DOID:7 0 0.651
connective tissue disease DOID:65 0 0.651