Danio rerio

0 known processes

srl

sarcalumenin

(Aliases: im:6899248,zgc:153844,wu:fb94b10)

srl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 20 0.608
cellular component assembly involved in morphogenesis GO:0010927 107 0.595
myofibril assembly GO:0030239 48 0.570
cellular component morphogenesis GO:0032989 336 0.552
striated muscle cell development GO:0055002 108 0.448
actomyosin structure organization GO:0031032 53 0.429
organelle assembly GO:0070925 110 0.349
actin cytoskeleton organization GO:0030036 63 0.313
regulation of membrane repolarization GO:0060306 1 0.286
heart contraction GO:0060047 71 0.244
striated muscle cell differentiation GO:0051146 129 0.241
regulation of muscle contraction GO:0006937 3 0.225
regionalization GO:0003002 274 0.223
regulation of ion transmembrane transporter activity GO:0032412 2 0.204
regulation of sequestering of calcium ion GO:0051282 4 0.201
muscle cell development GO:0055001 115 0.200
organelle organization GO:0006996 227 0.196
sequestering of metal ion GO:0051238 3 0.195
regulation of multicellular organismal process GO:0051239 277 0.191
maintenance of location GO:0051235 4 0.182
cardiac muscle cell development GO:0055013 20 0.177
cellular component assembly GO:0022607 170 0.176
cellular component biogenesis GO:0044085 178 0.175
muscle contraction GO:0006936 18 0.154
muscle structure development GO:0061061 196 0.149
regulation of metal ion transport GO:0010959 4 0.146
release of sequestered calcium ion into cytosol GO:0051209 3 0.143
actin filament based process GO:0030029 64 0.141
negative regulation of cellular process GO:0048523 283 0.138
muscle cell differentiation GO:0042692 139 0.134
regulation of calcium ion transport GO:0051924 2 0.131
sarcomere organization GO:0045214 26 0.120
heart development GO:0007507 313 0.120
regulation of biological quality GO:0065008 263 0.119
striated muscle contraction GO:0006941 12 0.118
regulation of protein polymerization GO:0032271 2 0.106
membrane repolarization GO:0086009 2 0.099
system process GO:0003008 185 0.097
cardiac muscle cell differentiation GO:0055007 30 0.096
regulation of system process GO:0044057 40 0.091
trabecula morphogenesis GO:0061383 2 0.090
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.088
heart process GO:0003015 71 0.085
glucose homeostasis GO:0042593 1 0.084
transmembrane transport GO:0055085 120 0.081
cytoskeleton organization GO:0007010 96 0.081
regulation of reproductive process GO:2000241 4 0.079
ventricular cardiac muscle tissue development GO:0003229 3 0.079
homeostatic process GO:0042592 142 0.078
circulatory system process GO:0003013 87 0.078
single organism organelle organization GO:1902589 199 0.076
actin polymerization or depolymerization GO:0008154 2 0.075
cytokinesis GO:0000910 3 0.073
single organism localization GO:1902578 225 0.072
segmentation GO:0035282 97 0.070
calcium ion transport GO:0006816 18 0.070
ion transport GO:0006811 114 0.069
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.068
negative regulation of biological process GO:0048519 304 0.067
cation homeostasis GO:0055080 33 0.064
response to corticosteroid GO:0031960 1 0.062
regulation of protein complex assembly GO:0043254 3 0.061
aging GO:0007568 2 0.061
protein polymerization GO:0051258 4 0.059
cell part morphogenesis GO:0032990 246 0.056
cardiac cell development GO:0055006 21 0.053
actin filament polymerization GO:0030041 2 0.052
regulation of metabolic process GO:0019222 359 0.052
heart morphogenesis GO:0003007 156 0.052
regulation of striated muscle contraction GO:0006942 2 0.051
regulation of cardiac muscle contraction GO:0055117 2 0.049
ion homeostasis GO:0050801 41 0.049
lipid storage GO:0019915 1 0.048
regulation of cell matrix adhesion GO:0001952 1 0.047
ubiquitin dependent protein catabolic process GO:0006511 3 0.047
blood circulation GO:0008015 87 0.047
organic acid metabolic process GO:0006082 31 0.047
transport GO:0006810 220 0.047
regulation of membrane potential GO:0042391 23 0.046
regulation of nucleoside metabolic process GO:0009118 2 0.046
cardiac myofibril assembly GO:0055003 9 0.045
larval development GO:0002164 2 0.045
carboxylic acid metabolic process GO:0019752 22 0.043
lipid digestion GO:0044241 3 0.042
regulation of heart contraction GO:0008016 32 0.042
maternal determination of anterior posterior axis embryo GO:0008358 4 0.040
positive regulation of transport GO:0051050 2 0.040
regulation of purine nucleotide catabolic process GO:0033121 2 0.040
proteasomal protein catabolic process GO:0010498 2 0.039
chemical homeostasis GO:0048878 49 0.038
regulation of cell substrate adhesion GO:0010810 1 0.038
striated muscle tissue development GO:0014706 110 0.037
inorganic cation transmembrane transport GO:0098662 50 0.037
regulation of protein complex disassembly GO:0043244 1 0.037
response to external stimulus GO:0009605 264 0.035
somite development GO:0061053 96 0.035
ventricular cardiac myofibril assembly GO:0055005 4 0.035
monovalent inorganic cation transport GO:0015672 42 0.035
regulation of cell communication GO:0010646 232 0.034
cellular macromolecular complex assembly GO:0034622 24 0.034
regulation of mrna splicing via spliceosome GO:0048024 3 0.034
macromolecular complex disassembly GO:0032984 1 0.033
regulation of nucleotide catabolic process GO:0030811 2 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.032
cytosolic calcium ion transport GO:0060401 3 0.032
rna localization GO:0006403 4 0.032
muscle fiber development GO:0048747 52 0.032
cell projection organization GO:0030030 284 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
meiotic nuclear division GO:0007126 4 0.032
pole plasm assembly GO:0007315 4 0.032
lipid homeostasis GO:0055088 3 0.031
cellular localization GO:0051641 97 0.031
regulation of cellular metabolic process GO:0031323 320 0.030
cardiac muscle tissue development GO:0048738 48 0.030
neurotransmitter secretion GO:0007269 2 0.030
localization of cell GO:0051674 244 0.030
somitogenesis GO:0001756 87 0.030
single organism transport GO:0044765 206 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
calcium ion transport into cytosol GO:0060402 3 0.029
cell substrate adhesion GO:0031589 4 0.029
axonogenesis GO:0007409 152 0.029
organic acid catabolic process GO:0016054 3 0.029
cardiocyte differentiation GO:0035051 44 0.029
protein localization to plasma membrane GO:0072659 1 0.028
regulation of signaling GO:0023051 235 0.028
cardiac muscle contraction GO:0060048 6 0.028
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.028
oxoacid metabolic process GO:0043436 31 0.028
cell morphogenesis GO:0000902 289 0.027
inorganic ion transmembrane transport GO:0098660 57 0.027
atp catabolic process GO:0006200 4 0.027
regulation of protein depolymerization GO:1901879 1 0.027
nucleoside monophosphate catabolic process GO:0009125 4 0.027
metal ion transport GO:0030001 58 0.027
metal ion homeostasis GO:0055065 26 0.027
regulation of response to stimulus GO:0048583 269 0.027
establishment of protein localization to plasma membrane GO:0090002 1 0.027
regulation of ion transmembrane transport GO:0034765 18 0.027
lamellipodium assembly GO:0030032 1 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.026
neuron projection development GO:0031175 180 0.026
generation of neurons GO:0048699 385 0.026
regulation of cell projection assembly GO:0060491 4 0.025
cell projection morphogenesis GO:0048858 244 0.025
cytoskeleton dependent cytokinesis GO:0061640 3 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
cell morphogenesis involved in differentiation GO:0000904 195 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
water homeostasis GO:0030104 4 0.024
carbohydrate homeostasis GO:0033500 1 0.024
mitochondrion organization GO:0007005 4 0.024
neuron differentiation GO:0030182 353 0.024
cellular modified amino acid metabolic process GO:0006575 3 0.024
cognition GO:0050890 1 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
regulation of cell shape GO:0008360 1 0.024
divalent inorganic cation homeostasis GO:0072507 22 0.024
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.023
cellular response to organic substance GO:0071310 105 0.023
adult behavior GO:0030534 2 0.023
cellular protein complex assembly GO:0043623 19 0.023
negative regulation of homeostatic process GO:0032845 5 0.023
divalent inorganic cation transport GO:0072511 21 0.023
cellular component movement GO:0006928 335 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
axon development GO:0061564 166 0.022
oocyte anterior posterior axis specification GO:0007314 4 0.022
regulation of transporter activity GO:0032409 2 0.022
calcium mediated signaling GO:0019722 2 0.022
regulation of binding GO:0051098 3 0.021
negative regulation of mapk cascade GO:0043409 4 0.021
neuromuscular synaptic transmission GO:0007274 2 0.021
negative regulation of signaling GO:0023057 96 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.020
plasma membrane repair GO:0001778 2 0.020
neuron projection morphogenesis GO:0048812 161 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
positive regulation of biological process GO:0048518 253 0.020
muscle tissue development GO:0060537 110 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
response to chemical GO:0042221 320 0.020
response to stress GO:0006950 263 0.019
regulation of signal transduction GO:0009966 225 0.019
cytoplasm organization GO:0007028 4 0.019
myelin assembly GO:0032288 1 0.019
cellular amino acid biosynthetic process GO:0008652 2 0.019
lamellipodium organization GO:0097581 1 0.019
cellular component disassembly GO:0022411 1 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.018
regulation of muscle system process GO:0090257 5 0.018
heart looping GO:0001947 94 0.018
organic substance transport GO:0071702 58 0.018
regulation of muscle hypertrophy GO:0014743 2 0.018
establishment of localization in cell GO:0051649 77 0.018
establishment of localization GO:0051234 244 0.018
regulation of cellular component size GO:0032535 30 0.018
intracellular mrna localization GO:0008298 1 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.017
neuron development GO:0048666 262 0.017
fatty acid beta oxidation GO:0006635 1 0.017
ion transmembrane transport GO:0034220 91 0.017
small molecule catabolic process GO:0044282 3 0.017
biological adhesion GO:0022610 40 0.017
signal transduction GO:0007165 455 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
small molecule metabolic process GO:0044281 77 0.017
cellular homeostasis GO:0019725 26 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
nitric oxide biosynthetic process GO:0006809 2 0.017
multi organism process GO:0051704 134 0.017
nucleic acid transport GO:0050657 2 0.017
cilium morphogenesis GO:0060271 85 0.016
regulation of protein binding GO:0043393 3 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
neurotransmitter transport GO:0006836 2 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
cellular biosynthetic process GO:0044249 286 0.016
embryonic organ development GO:0048568 381 0.016
cellular protein catabolic process GO:0044257 4 0.016
cation transport GO:0006812 81 0.016
regulation of developmental process GO:0050793 247 0.016
cardiac chamber morphogenesis GO:0003206 12 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
spermatid development GO:0007286 2 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cardiac muscle fiber development GO:0048739 3 0.015
heterocycle metabolic process GO:0046483 290 0.015
cardiac ventricle formation GO:0003211 1 0.015
endocardial cushion formation GO:0003272 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
intracellular signal transduction GO:0035556 85 0.015
spermatid differentiation GO:0048515 2 0.015
pyruvate metabolic process GO:0006090 1 0.015
pronephros development GO:0048793 69 0.014
regulation of blood pressure GO:0008217 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of blood circulation GO:1903522 32 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
cellular response to steroid hormone stimulus GO:0071383 31 0.014
protein complex assembly GO:0006461 30 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
lipid catabolic process GO:0016042 4 0.014
divalent metal ion transport GO:0070838 20 0.014
mitotic cytokinesis GO:0000281 3 0.014
single organism biosynthetic process GO:0044711 71 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
reproduction GO:0000003 40 0.013
anatomical structure homeostasis GO:0060249 36 0.013
cation transmembrane transport GO:0098655 65 0.013
nucleobase containing compound transport GO:0015931 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
regulation of primary metabolic process GO:0080090 311 0.013
cardiac chamber development GO:0003205 19 0.013
nucleoside triphosphate biosynthetic process GO:0009142 2 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
cell matrix adhesion GO:0007160 4 0.013
chordate embryonic development GO:0043009 271 0.013
skeletal muscle thin filament assembly GO:0030240 4 0.013
regulation of cellular component organization GO:0051128 86 0.013
cellular response to unfolded protein GO:0034620 2 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
growth GO:0040007 174 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
cellular ion homeostasis GO:0006873 17 0.013
lipid oxidation GO:0034440 1 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
protein depolymerization GO:0051261 1 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
positive regulation of secretion GO:0051047 1 0.012
ceramide biosynthetic process GO:0046513 1 0.012
negative regulation of cellular component organization GO:0051129 16 0.012
lymphoid lineage cell migration GO:0097534 4 0.012
post embryonic organ development GO:0048569 4 0.012
actin filament based movement GO:0030048 1 0.012
macromolecule modification GO:0043412 111 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
gene expression GO:0010467 252 0.012
positive regulation of blood circulation GO:1903524 2 0.012
hemopoiesis GO:0030097 183 0.012
regulation of cell adhesion GO:0030155 15 0.012
cardiac ventricle development GO:0003231 9 0.012
regulation of dendrite development GO:0050773 3 0.011
ventricular cardiac muscle cell differentiation GO:0055012 6 0.011
cell cycle GO:0007049 93 0.011
multicellular organism growth GO:0035264 4 0.011
organelle localization GO:0051640 49 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
protein import GO:0017038 3 0.011
negative regulation of signal transduction GO:0009968 94 0.011
homeostasis of number of cells GO:0048872 62 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
negative regulation of jnk cascade GO:0046329 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
response to glucocorticoid GO:0051384 1 0.011
stem cell proliferation GO:0072089 4 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
cell adhesion GO:0007155 40 0.011
cell projection assembly GO:0030031 64 0.011
cardiac ventricle morphogenesis GO:0003208 7 0.011
single organism metabolic process GO:0044710 217 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
axoneme assembly GO:0035082 9 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
locomotion GO:0040011 313 0.011
negative regulation of kinase activity GO:0033673 4 0.011
calcium ion import GO:0070509 4 0.011
cellular protein complex disassembly GO:0043624 1 0.011
post embryonic morphogenesis GO:0009886 4 0.011
protein secretion GO:0009306 1 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of release of sequestered calcium ion into cytosol GO:0051279 1 0.010
behavior GO:0007610 74 0.010
protein complex disassembly GO:0043241 1 0.010
developmental growth GO:0048589 166 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
patterning of blood vessels GO:0001569 15 0.010
trabecula formation GO:0060343 2 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010

srl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.205
musculoskeletal system disease DOID:17 0 0.205
myopathy DOID:423 0 0.202
muscular disease DOID:0080000 0 0.202
muscle tissue disease DOID:66 0 0.202
distal arthrogryposis DOID:0050646 0 0.091
cardiovascular system disease DOID:1287 0 0.057
hypertrophic cardiomyopathy DOID:11984 0 0.056
heart disease DOID:114 0 0.056
cardiomyopathy DOID:0050700 0 0.056
intrinsic cardiomyopathy DOID:0060036 0 0.056
immune system disease DOID:2914 0 0.013