Danio rerio

19 known processes

paics

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

(Aliases: sb:cb293,cb293,wu:fa28a05)

paics biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.630
Worm
pigmentation GO:0043473 85 0.491
eye development GO:0001654 277 0.429
single organism metabolic process GO:0044710 217 0.409
embryo development ending in birth or egg hatching GO:0009792 271 0.343
camera type eye development GO:0043010 222 0.337
phosphate containing compound metabolic process GO:0006796 108 0.257
maintenance of location GO:0051235 4 0.231
sensory organ development GO:0007423 393 0.224
sensory organ morphogenesis GO:0090596 200 0.182
organic cyclic compound biosynthetic process GO:1901362 223 0.133
hemopoiesis GO:0030097 183 0.129
developmental pigmentation GO:0048066 48 0.114
pigment cell differentiation GO:0050931 38 0.110
organic acid metabolic process GO:0006082 31 0.106
single organism transport GO:0044765 206 0.105
organonitrogen compound metabolic process GO:1901564 74 0.103
alpha amino acid metabolic process GO:1901605 3 0.100
locomotion GO:0040011 313 0.097
response to stress GO:0006950 263 0.094
phosphorus metabolic process GO:0006793 109 0.091
small molecule metabolic process GO:0044281 77 0.091
organic substance biosynthetic process GO:1901576 289 0.090
nucleobase containing compound metabolic process GO:0006139 274 0.086
response to lipid GO:0033993 60 0.084
gene expression GO:0010467 252 0.083
regulation of multicellular organismal development GO:2000026 223 0.083
regeneration GO:0031099 91 0.082
carboxylic acid metabolic process GO:0019752 22 0.081
epithelial cell differentiation GO:0030855 116 0.079
retina development in camera type eye GO:0060041 146 0.078
lipid storage GO:0019915 1 0.076
response to wounding GO:0009611 116 0.076
programmed cell death GO:0012501 119 0.076
wound healing GO:0042060 90 0.073
response to organic substance GO:0010033 153 0.072
organic cyclic compound metabolic process GO:1901360 301 0.070
embryonic organ development GO:0048568 381 0.067
gland development GO:0048732 143 0.064
hepaticobiliary system development GO:0061008 98 0.064
tube morphogenesis GO:0035239 349 0.063
nitrogen compound metabolic process GO:0006807 319 0.063
oxoacid metabolic process GO:0043436 31 0.061
aging GO:0007568 2 0.059
heterocycle biosynthetic process GO:0018130 215 0.059
head development GO:0060322 303 0.057
amine metabolic process GO:0009308 2 0.056
cellular amino acid metabolic process GO:0006520 7 0.055
liver development GO:0001889 96 0.055
response to hormone GO:0009725 48 0.055
central nervous system development GO:0007417 387 0.054
neural retina development GO:0003407 49 0.054
regulation of multicellular organism growth GO:0040014 4 0.054
aromatic compound biosynthetic process GO:0019438 217 0.054
positive regulation of biological process GO:0048518 253 0.053
camera type eye morphogenesis GO:0048593 108 0.053
reproductive process GO:0022414 40 0.052
organonitrogen compound biosynthetic process GO:1901566 47 0.052
multi organism process GO:0051704 134 0.052
fin regeneration GO:0031101 51 0.051
ribosomal small subunit biogenesis GO:0042274 2 0.051
regulation of cellular amine metabolic process GO:0033238 0 0.051
regulation of primary metabolic process GO:0080090 311 0.049
establishment of localization GO:0051234 244 0.049
response to chemical GO:0042221 320 0.049
meiotic nuclear division GO:0007126 4 0.046
cellular response to chemical stimulus GO:0070887 157 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.045
tissue remodeling GO:0048771 4 0.045
response to oxygen containing compound GO:1901700 55 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.044
chordate embryonic development GO:0043009 271 0.044
nucleobase containing small molecule metabolic process GO:0055086 32 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
oxidation reduction process GO:0055114 41 0.042
phagocytosis GO:0006909 3 0.042
cellular amine metabolic process GO:0044106 2 0.041
regulation of histone methylation GO:0031060 3 0.041
leukocyte proliferation GO:0070661 1 0.041
cellular biosynthetic process GO:0044249 286 0.041
eye morphogenesis GO:0048592 144 0.041
cellular amino acid biosynthetic process GO:0008652 2 0.040
positive regulation of transport GO:0051050 2 0.039
proteasomal protein catabolic process GO:0010498 2 0.038
tissue regeneration GO:0042246 74 0.038
organelle organization GO:0006996 227 0.037
nuclear export GO:0051168 1 0.037
response to endogenous stimulus GO:0009719 83 0.037
regionalization GO:0003002 274 0.036
macromolecule modification GO:0043412 111 0.036
response to drug GO:0042493 3 0.036
neurotransmitter secretion GO:0007269 2 0.036
heart development GO:0007507 313 0.036
blood vessel development GO:0001568 246 0.036
regulation of cellular metabolic process GO:0031323 320 0.035
regulation of signaling GO:0023051 235 0.035
response to organic cyclic compound GO:0014070 51 0.034
nucleic acid metabolic process GO:0090304 244 0.034
meiotic cell cycle process GO:1903046 3 0.034
regulation of developmental process GO:0050793 247 0.033
signal transduction GO:0007165 455 0.032
regulation of protein binding GO:0043393 3 0.032
cellular response to lipid GO:0071396 39 0.032
atp catabolic process GO:0006200 4 0.032
cellular response to external stimulus GO:0071496 2 0.031
rna localization GO:0006403 4 0.031
negative regulation of biological process GO:0048519 304 0.030
modification dependent protein catabolic process GO:0019941 3 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
regulation of apoptotic process GO:0042981 98 0.030
transmembrane transport GO:0055085 120 0.030
apoptotic process GO:0006915 116 0.029
developmental growth GO:0048589 166 0.029
negative regulation of cellular process GO:0048523 283 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
cellular ketone metabolic process GO:0042180 11 0.028
male meiosis GO:0007140 2 0.027
lymphocyte proliferation GO:0046651 1 0.027
muscle structure development GO:0061061 196 0.026
single organism reproductive process GO:0044702 40 0.026
response to external stimulus GO:0009605 264 0.026
single organism biosynthetic process GO:0044711 71 0.026
digestive tract development GO:0048565 265 0.025
rna transport GO:0050658 2 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.024
regulation of cell death GO:0010941 103 0.024
regulation of signal transduction GO:0009966 225 0.024
spinal cord development GO:0021510 46 0.024
death GO:0016265 121 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
retina morphogenesis in camera type eye GO:0060042 79 0.023
negative regulation of ras protein signal transduction GO:0046580 1 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of binding GO:0051098 3 0.023
nucleic acid transport GO:0050657 2 0.023
vasculature development GO:0001944 278 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
rna metabolic process GO:0016070 219 0.022
response to ketone GO:1901654 1 0.022
odontogenesis of dentin containing tooth GO:0042475 1 0.022
negative regulation of signaling GO:0023057 96 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
multi organism reproductive process GO:0044703 36 0.021
single organism localization GO:1902578 225 0.021
response to radiation GO:0009314 51 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
regulation of biological quality GO:0065008 263 0.021
nuclear transport GO:0051169 4 0.021
regulation of localization GO:0032879 104 0.021
notochord development GO:0030903 54 0.021
growth GO:0040007 174 0.020
positive regulation of catabolic process GO:0009896 4 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
immune system development GO:0002520 191 0.020
regulation of metal ion transport GO:0010959 4 0.020
cellular response to hormone stimulus GO:0032870 39 0.020
reproduction GO:0000003 40 0.020
cellular macromolecule metabolic process GO:0044260 391 0.019
system process GO:0003008 185 0.019
transport GO:0006810 220 0.019
stem cell proliferation GO:0072089 4 0.019
cartilage development GO:0051216 96 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
brain development GO:0007420 293 0.019
central nervous system neuron differentiation GO:0021953 74 0.019
autophagy GO:0006914 4 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
multicellular organism growth GO:0035264 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
endocytosis GO:0006897 16 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
vesicle mediated transport GO:0016192 22 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
regulation of programmed cell death GO:0043067 101 0.018
cellular protein modification process GO:0006464 100 0.018
regulation of intracellular signal transduction GO:1902531 57 0.017
developmental process involved in reproduction GO:0003006 27 0.017
response to steroid hormone GO:0048545 35 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
cell cycle GO:0007049 93 0.017
mononuclear cell proliferation GO:0032943 1 0.017
neurological system process GO:0050877 62 0.017
regulation of cell shape GO:0008360 1 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
cellular response to organic substance GO:0071310 105 0.016
cellular localization GO:0051641 97 0.016
biosynthetic process GO:0009058 294 0.016
positive regulation of metabolic process GO:0009893 108 0.016
cellular component assembly GO:0022607 170 0.016
protein import into nucleus GO:0006606 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
protein modification process GO:0036211 100 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
heterocycle metabolic process GO:0046483 290 0.015
cell projection morphogenesis GO:0048858 244 0.015
response to abiotic stimulus GO:0009628 122 0.015
single fertilization GO:0007338 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of transcription dna templated GO:0006355 213 0.015
transmission of nerve impulse GO:0019226 19 0.015
immune system process GO:0002376 241 0.015
eye pigmentation GO:0048069 4 0.015
regulation of myotube differentiation GO:0010830 2 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
regulation of molecular function GO:0065009 70 0.015
protein metabolic process GO:0019538 183 0.015
regulation of metabolic process GO:0019222 359 0.015
regulation of developmental pigmentation GO:0048070 6 0.014
digestive system development GO:0055123 289 0.014
organic substance transport GO:0071702 58 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
cellular protein catabolic process GO:0044257 4 0.014
establishment of rna localization GO:0051236 3 0.014
gtp metabolic process GO:0046039 4 0.014
epithelial cell development GO:0002064 42 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
nucleobase containing compound transport GO:0015931 2 0.014
gtp catabolic process GO:0006184 2 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
connective tissue development GO:0061448 99 0.014
regulation of protein transport GO:0051223 3 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
meiotic spindle organization GO:0000212 1 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
regulation of cytokine production GO:0001817 3 0.014
regulation of retina development in camera type eye GO:1902866 2 0.014
nucleus organization GO:0006997 7 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
homeostasis of number of cells within a tissue GO:0048873 4 0.014
cellular response to steroid hormone stimulus GO:0071383 31 0.013
response to hexose GO:0009746 3 0.013
cell death GO:0008219 121 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
long chain fatty acid transport GO:0015909 1 0.013
regulation of gene expression GO:0010468 265 0.013
muscle tissue development GO:0060537 110 0.013
regulation of organelle assembly GO:1902115 4 0.013
protein stabilization GO:0050821 2 0.013
fin development GO:0033333 77 0.013
cellular protein metabolic process GO:0044267 129 0.013
neuron development GO:0048666 262 0.013
myeloid cell homeostasis GO:0002262 56 0.013
cellular component movement GO:0006928 335 0.013
negative regulation of cell death GO:0060548 60 0.013
regulation of cell communication GO:0010646 232 0.012
regulation of jun kinase activity GO:0043506 3 0.012
skin development GO:0043588 54 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
homeostatic process GO:0042592 142 0.012
multicellular organismal homeostasis GO:0048871 29 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cellular lipid metabolic process GO:0044255 36 0.012
anterior posterior pattern specification GO:0009952 152 0.012
protein complex subunit organization GO:0071822 46 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
anion transport GO:0006820 38 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
cellular component disassembly GO:0022411 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
regulation of cell cycle GO:0051726 52 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
positive regulation of cell cycle GO:0045787 3 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
cognition GO:0050890 1 0.011
carboxylic acid transport GO:0046942 8 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
nuclear import GO:0051170 3 0.011
cellular catabolic process GO:0044248 27 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
ion transport GO:0006811 114 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.011
notochord cell development GO:0060035 9 0.011
organic anion transport GO:0015711 15 0.011
renal system development GO:0072001 94 0.011
organophosphate metabolic process GO:0019637 37 0.011
appendage development GO:0048736 80 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.011
regulation of cell activation GO:0050865 1 0.011
neuroepithelial cell differentiation GO:0060563 26 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
spindle assembly involved in meiosis GO:0090306 1 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cell proliferation GO:0008283 80 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
protein import GO:0017038 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
tissue homeostasis GO:0001894 25 0.011
rna export from nucleus GO:0006405 1 0.011
regulation of blood pressure GO:0008217 1 0.010
organic acid transport GO:0015849 9 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
striated muscle tissue development GO:0014706 110 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
small molecule catabolic process GO:0044282 3 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
negative regulation of multi organism process GO:0043901 3 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
intracellular signal transduction GO:0035556 85 0.010
response to fatty acid GO:0070542 5 0.010
pancreas development GO:0031016 84 0.010
glial cell differentiation GO:0010001 42 0.010

paics disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
nervous system disease DOID:863 0 0.034
x linked disease DOID:0050735 0 0.028
auditory system disease DOID:2742 0 0.011
nonsyndromic deafness DOID:0050563 0 0.011
sensory system disease DOID:0050155 0 0.011
immune system disease DOID:2914 0 0.011