Danio rerio

0 known processes

rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

(Aliases: si:dkey-27m20.2)

rapgef3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.063
aging GO:0007568 2 0.055
positive regulation of transport GO:0051050 2 0.053
maintenance of location GO:0051235 4 0.047
sensory organ development GO:0007423 393 0.041
dicarboxylic acid transport GO:0006835 1 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
stem cell proliferation GO:0072089 4 0.034
phagocytosis GO:0006909 3 0.034
regulation of synapse organization GO:0050807 3 0.034
lipid storage GO:0019915 1 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
endosomal transport GO:0016197 2 0.031
cell projection organization GO:0030030 284 0.030
stem cell maintenance GO:0019827 4 0.029
multicellular organism growth GO:0035264 4 0.029
cognition GO:0050890 1 0.027
regulation of synapse assembly GO:0051963 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
adherens junction organization GO:0034332 4 0.027
response to drug GO:0042493 3 0.026
regulation of reproductive process GO:2000241 4 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.025
cellular component movement GO:0006928 335 0.024
heart development GO:0007507 313 0.024
exocytosis GO:0006887 1 0.024
neurotransmitter transport GO:0006836 2 0.024
regulation of biological quality GO:0065008 263 0.023
central nervous system development GO:0007417 387 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
embryonic organ development GO:0048568 381 0.023
regulation of muscle contraction GO:0006937 3 0.022
synaptic vesicle localization GO:0097479 1 0.022
mitochondrion organization GO:0007005 4 0.022
nucleoside monophosphate catabolic process GO:0009125 4 0.022
eye development GO:0001654 277 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
synaptic vesicle transport GO:0048489 1 0.022
compound eye development GO:0048749 2 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
cell migration GO:0016477 237 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
neuron development GO:0048666 262 0.021
response to external stimulus GO:0009605 264 0.021
positive regulation of catabolic process GO:0009896 4 0.021
cytokinesis GO:0000910 3 0.021
spermatid differentiation GO:0048515 2 0.021
cell morphogenesis GO:0000902 289 0.021
single organism transport GO:0044765 206 0.020
establishment of localization GO:0051234 244 0.020
post embryonic organ development GO:0048569 4 0.020
single organism membrane fusion GO:0044801 2 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
neurotransmitter secretion GO:0007269 2 0.020
spermatid development GO:0007286 2 0.020
regulation of cell activation GO:0050865 1 0.020
transport GO:0006810 220 0.020
neuron differentiation GO:0030182 353 0.020
response to chemical GO:0042221 320 0.020
regulation of developmental process GO:0050793 247 0.020
guanosine containing compound metabolic process GO:1901068 4 0.019
system process GO:0003008 185 0.019
cellular amine metabolic process GO:0044106 2 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
membrane fusion GO:0061025 2 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
neuroblast proliferation GO:0007405 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
protein polymerization GO:0051258 4 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
localization of cell GO:0051674 244 0.018
regulation of tube size GO:0035150 2 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
amino acid transport GO:0006865 2 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of blood vessel size GO:0050880 2 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
sensory perception of chemical stimulus GO:0007606 3 0.018
amine metabolic process GO:0009308 2 0.018
positive regulation of protein polymerization GO:0032273 2 0.018
ion transmembrane transport GO:0034220 91 0.018
hemopoiesis GO:0030097 183 0.017
actin filament polymerization GO:0030041 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
cell projection morphogenesis GO:0048858 244 0.017
atp catabolic process GO:0006200 4 0.017
locomotion GO:0040011 313 0.017
cellular ketone metabolic process GO:0042180 11 0.017
regulation of blood pressure GO:0008217 1 0.017
gtp metabolic process GO:0046039 4 0.017
sequestering of metal ion GO:0051238 3 0.017
response to carbohydrate GO:0009743 3 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
cell part morphogenesis GO:0032990 246 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
leukocyte proliferation GO:0070661 1 0.017
regulation of cell shape GO:0008360 1 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
chemosensory behavior GO:0007635 1 0.017
regulation of protein polymerization GO:0032271 2 0.017
carbohydrate homeostasis GO:0033500 1 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
organelle fusion GO:0048284 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
nuclear transport GO:0051169 4 0.016
cellular component morphogenesis GO:0032989 336 0.016
female gonad development GO:0008585 4 0.016
adult behavior GO:0030534 2 0.016
regulation of protein complex assembly GO:0043254 3 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
somatic muscle development GO:0007525 4 0.016
stem cell division GO:0017145 1 0.016
fertilization GO:0009566 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
neuromuscular process controlling balance GO:0050885 3 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
positive regulation of immune effector process GO:0002699 3 0.016
generation of neurons GO:0048699 385 0.016
ion transport GO:0006811 114 0.016
single organism metabolic process GO:0044710 217 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
b cell activation GO:0042113 2 0.015
response to amphetamine GO:0001975 1 0.015
negative regulation of biological process GO:0048519 304 0.015
organic acid metabolic process GO:0006082 31 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of mrna processing GO:0050684 3 0.015
small molecule metabolic process GO:0044281 77 0.015
posterior lateral line system development GO:0048915 46 0.015
sequestering of calcium ion GO:0051208 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
response to amino acid GO:0043200 2 0.015
organelle organization GO:0006996 227 0.015
regulation of metal ion transport GO:0010959 4 0.015
single organism localization GO:1902578 225 0.015
regulation of protein transport GO:0051223 3 0.015
cellular protein catabolic process GO:0044257 4 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
axonogenesis GO:0007409 152 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
proteasomal protein catabolic process GO:0010498 2 0.014
protein acetylation GO:0006473 2 0.014
regulation of binding GO:0051098 3 0.014
protein localization to nucleus GO:0034504 3 0.014
autophagy GO:0006914 4 0.014
regulation of transporter activity GO:0032409 2 0.014
response to stress GO:0006950 263 0.014
transmission of nerve impulse GO:0019226 19 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
regulation of striated muscle contraction GO:0006942 2 0.014
regulation of gene expression GO:0010468 265 0.014
immune system process GO:0002376 241 0.014
taxis GO:0042330 109 0.014
vacuolar transport GO:0007034 2 0.014
single fertilization GO:0007338 3 0.014
regulation of metabolic process GO:0019222 359 0.014
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
neurological system process GO:0050877 62 0.014
positive regulation of secretion GO:0051047 1 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
protein homooligomerization GO:0051260 3 0.014
muscle structure development GO:0061061 196 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
mechanosensory lateral line system development GO:0048881 49 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular response to nutrient levels GO:0031669 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.013
blood circulation GO:0008015 87 0.013
protein acylation GO:0043543 3 0.013
response to uv GO:0009411 3 0.013
signal transduction GO:0007165 455 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
camera type eye development GO:0043010 222 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
meiotic cell cycle process GO:1903046 3 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
homeostatic process GO:0042592 142 0.013
cellular biosynthetic process GO:0044249 286 0.013
regulation of cytokine production GO:0001817 3 0.013
protein complex disassembly GO:0043241 1 0.013
smooth muscle contraction GO:0006939 2 0.013
rna localization GO:0006403 4 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.013
protein import into nucleus GO:0006606 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
sensory organ morphogenesis GO:0090596 200 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
cell motility GO:0048870 244 0.013
regulation of endocrine process GO:0044060 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
cellular response to external stimulus GO:0071496 2 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
oxoacid metabolic process GO:0043436 31 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
lymphocyte proliferation GO:0046651 1 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
phagocytosis engulfment GO:0006911 1 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
golgi vesicle transport GO:0048193 3 0.012
response to alkaloid GO:0043279 2 0.012
head development GO:0060322 303 0.012
muscle cell development GO:0055001 115 0.012
glucose homeostasis GO:0042593 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
immune system development GO:0002520 191 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
protein heterooligomerization GO:0051291 1 0.012
transmembrane transport GO:0055085 120 0.012
glial cell migration GO:0008347 3 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
positive regulation of cell killing GO:0031343 2 0.012
response to monosaccharide GO:0034284 3 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
response to hexose GO:0009746 3 0.012
protein import GO:0017038 3 0.012
striated muscle cell development GO:0055002 108 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
brain development GO:0007420 293 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
response to vitamin GO:0033273 3 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
nuclear import GO:0051170 3 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
regionalization GO:0003002 274 0.012
negative regulation of catabolic process GO:0009895 3 0.012
protein dephosphorylation GO:0006470 3 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of membrane potential GO:0042391 23 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of signaling GO:0023051 235 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
blood vessel development GO:0001568 246 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
macroautophagy GO:0016236 1 0.011
female sex differentiation GO:0046660 4 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
mechanosensory behavior GO:0007638 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
locomotor rhythm GO:0045475 3 0.011
startle response GO:0001964 4 0.011
determination of bilateral symmetry GO:0009855 204 0.011
membrane invagination GO:0010324 1 0.011
cellular response to starvation GO:0009267 1 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
lipid homeostasis GO:0055088 3 0.011
actin filament based movement GO:0030048 1 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
heart morphogenesis GO:0003007 156 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
posterior lateral line development GO:0048916 38 0.011
endocrine process GO:0050886 2 0.011
mononuclear cell proliferation GO:0032943 1 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
single organism organelle organization GO:1902589 199 0.011
peptide transport GO:0015833 1 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
heterocycle metabolic process GO:0046483 290 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
chemotaxis GO:0006935 104 0.011
neuron projection development GO:0031175 180 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
forebrain development GO:0030900 96 0.011
regulation of hormone secretion GO:0046883 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
developmental growth GO:0048589 166 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
single organism nuclear import GO:1902593 3 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
specification of symmetry GO:0009799 204 0.010
regulation of circadian rhythm GO:0042752 4 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
eye morphogenesis GO:0048592 144 0.010
protein targeting to membrane GO:0006612 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
regulation of cellular ph GO:0030641 1 0.010
nuclear export GO:0051168 1 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
positive regulation of cell activation GO:0050867 1 0.010
tube morphogenesis GO:0035239 349 0.010
response to glucose GO:0009749 3 0.010
alcohol biosynthetic process GO:0046165 2 0.010
cellular response to light stimulus GO:0071482 4 0.010
organic substance biosynthetic process GO:1901576 289 0.010
interspecies interaction between organisms GO:0044419 4 0.010
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
gene expression GO:0010467 252 0.010
hormone transport GO:0009914 2 0.010
somatic stem cell maintenance GO:0035019 1 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
regulation of sodium ion transport GO:0002028 2 0.010
neuronal action potential GO:0019228 18 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
cellular component assembly GO:0022607 170 0.010
lipid catabolic process GO:0016042 4 0.010
positive regulation of biological process GO:0048518 253 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010

rapgef3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.018
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
immune system disease DOID:2914 0 0.014
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011