Danio rerio

0 known processes

atp5a1

ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

(Aliases: zgc:154103)

atp5a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular respiration GO:0045333 3 0.241
larval development GO:0002164 2 0.236
Worm
inorganic cation transmembrane transport GO:0098662 50 0.227
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.213
Human Mouse
cation transmembrane transport GO:0098655 65 0.189
Mouse
purine containing compound metabolic process GO:0072521 29 0.189
Human Mouse
ion transport GO:0006811 114 0.152
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.148
Human Mouse
ribonucleotide metabolic process GO:0009259 27 0.136
Human Mouse
aging GO:0007568 2 0.134
Worm
purine nucleotide metabolic process GO:0006163 27 0.127
Human Mouse
mitochondrion organization GO:0007005 4 0.122
programmed cell death GO:0012501 119 0.114
Worm
nitrogen compound metabolic process GO:0006807 319 0.111
Human Mouse
ion transmembrane transport GO:0034220 91 0.108
Mouse
reactive oxygen species metabolic process GO:0072593 6 0.091
cellular aromatic compound metabolic process GO:0006725 295 0.090
Human Mouse
central nervous system development GO:0007417 387 0.085
maintenance of location GO:0051235 4 0.075
organonitrogen compound metabolic process GO:1901564 74 0.074
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.072
oxidative phosphorylation GO:0006119 1 0.072
organic cyclic compound metabolic process GO:1901360 301 0.070
Human Mouse
ribose phosphate metabolic process GO:0019693 27 0.069
Human Mouse
regulation of membrane potential GO:0042391 23 0.065
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.064
Human Mouse
single organism biosynthetic process GO:0044711 71 0.064
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
nucleobase containing compound metabolic process GO:0006139 274 0.060
Human Mouse
energy derivation by oxidation of organic compounds GO:0015980 5 0.060
multicellular organism growth GO:0035264 4 0.057
intracellular signal transduction GO:0035556 85 0.054
organelle organization GO:0006996 227 0.054
apoptotic process GO:0006915 116 0.053
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.052
Human Mouse
cell death GO:0008219 121 0.051
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.050
Worm
lipid storage GO:0019915 1 0.049
single organism metabolic process GO:0044710 217 0.046
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 43 0.046
guanosine containing compound metabolic process GO:1901068 4 0.045
protein acetylation GO:0006473 2 0.045
neurotransmitter transport GO:0006836 2 0.044
response to stress GO:0006950 263 0.044
regulation of macromolecule metabolic process GO:0060255 317 0.044
small molecule metabolic process GO:0044281 77 0.042
Human Mouse
purine containing compound biosynthetic process GO:0072522 20 0.042
positive regulation of cytokine production GO:0001819 2 0.041
transport GO:0006810 220 0.040
Mouse
ribonucleoside metabolic process GO:0009119 11 0.039
Human Mouse
gtp metabolic process GO:0046039 4 0.039
establishment of localization GO:0051234 244 0.038
Mouse
head development GO:0060322 303 0.038
atp catabolic process GO:0006200 4 0.037
Human Mouse
cation transport GO:0006812 81 0.036
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.035
inorganic ion transmembrane transport GO:0098660 57 0.034
Mouse
nucleotide metabolic process GO:0009117 28 0.034
Human Mouse
phosphate containing compound metabolic process GO:0006796 108 0.034
Human Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.034
transmembrane transport GO:0055085 120 0.034
Mouse
cellular component movement GO:0006928 335 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
gtp catabolic process GO:0006184 2 0.032
regulation of cellular response to oxidative stress GO:1900407 2 0.032
cellular amide metabolic process GO:0043603 4 0.031
hemopoiesis GO:0030097 183 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.030
positive regulation of apoptotic signaling pathway GO:2001235 1 0.030
electron transport chain GO:0022900 2 0.029
oxoacid metabolic process GO:0043436 31 0.029
nucleoside phosphate metabolic process GO:0006753 28 0.028
Human Mouse
organic acid metabolic process GO:0006082 31 0.028
carboxylic acid metabolic process GO:0019752 22 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
regulation of response to stimulus GO:0048583 269 0.026
nucleoside metabolic process GO:0009116 11 0.026
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
ribonucleotide biosynthetic process GO:0009260 20 0.026
anion transport GO:0006820 38 0.026
regulation of protein complex assembly GO:0043254 3 0.025
response to oxygen levels GO:0070482 25 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
nucleotide biosynthetic process GO:0009165 21 0.025
peptide metabolic process GO:0006518 1 0.025
nucleoside triphosphate biosynthetic process GO:0009142 2 0.025
activation of mapk activity GO:0000187 3 0.024
regulation of dna templated transcription in response to stress GO:0043620 0 0.024
adult behavior GO:0030534 2 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
response to external stimulus GO:0009605 264 0.024
protein modification process GO:0036211 100 0.023
ventricular cardiac muscle tissue development GO:0003229 3 0.023
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.023
signal transduction GO:0007165 455 0.023
cellular biosynthetic process GO:0044249 286 0.023
response to organic substance GO:0010033 153 0.023
response to oxygen radical GO:0000305 2 0.023
response to hypoxia GO:0001666 25 0.023
multi organism process GO:0051704 134 0.022
rna localization GO:0006403 4 0.022
negative regulation of cytoplasmic transport GO:1903650 2 0.022
cell proliferation GO:0008283 80 0.022
Human
purine ribonucleoside metabolic process GO:0046128 10 0.022
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
generation of neurons GO:0048699 385 0.022
cell migration GO:0016477 237 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.022
amine metabolic process GO:0009308 2 0.022
regulation of reproductive process GO:2000241 4 0.022
protein stabilization GO:0050821 2 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
cell motility GO:0048870 244 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
Human Mouse
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
Human Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
synaptic transmission cholinergic GO:0007271 4 0.021
nuclear transport GO:0051169 4 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
oxidation reduction process GO:0055114 41 0.020
localization of cell GO:0051674 244 0.020
cellular protein catabolic process GO:0044257 4 0.020
immune system process GO:0002376 241 0.019
regulation of cytokine production GO:0001817 3 0.019
response to biotic stimulus GO:0009607 97 0.019
atp synthesis coupled electron transport GO:0042773 1 0.019
regulation of biological quality GO:0065008 263 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
phosphorus metabolic process GO:0006793 109 0.019
Human Mouse
purine ribonucleotide metabolic process GO:0009150 27 0.019
Human Mouse
production of molecular mediator of immune response GO:0002440 2 0.019
heterocycle catabolic process GO:0046700 15 0.019
Human Mouse
anion transmembrane transport GO:0098656 12 0.019
death GO:0016265 121 0.019
Worm
single organism localization GO:1902578 225 0.018
Mouse
organophosphate metabolic process GO:0019637 37 0.018
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.018
regulation of response to oxidative stress GO:1902882 2 0.018
zymogen activation GO:0031638 3 0.018
embryonic organ development GO:0048568 381 0.018
cell aging GO:0007569 2 0.018
regulation of binding GO:0051098 3 0.017
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.017
reactive oxygen species biosynthetic process GO:1903409 1 0.017
gene expression GO:0010467 252 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
autophagy GO:0006914 4 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
lipid homeostasis GO:0055088 3 0.017
dicarboxylic acid metabolic process GO:0043648 1 0.017
regulation of signaling GO:0023051 235 0.017
negative regulation of biological process GO:0048519 304 0.017
Human
meiotic cell cycle process GO:1903046 3 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
reproduction GO:0000003 40 0.017
Worm
coenzyme biosynthetic process GO:0009108 2 0.017
biosynthetic process GO:0009058 294 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
developmental programmed cell death GO:0010623 4 0.017
cellular transition metal ion homeostasis GO:0046916 3 0.017
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.016
regulation of autophagy GO:0010506 3 0.016
immune system development GO:0002520 191 0.016
regulation of programmed cell death GO:0043067 101 0.016
carbohydrate homeostasis GO:0033500 1 0.016
action potential GO:0001508 19 0.016
purine nucleotide biosynthetic process GO:0006164 20 0.016
heart morphogenesis GO:0003007 156 0.016
negative regulation of protein transport GO:0051224 3 0.016
actin filament based movement GO:0030048 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
nucleic acid transport GO:0050657 2 0.015
regulation of primary metabolic process GO:0080090 311 0.015
cellular response to superoxide GO:0071451 2 0.015
stem cell proliferation GO:0072089 4 0.015
cell death in response to oxidative stress GO:0036473 2 0.015
establishment of rna localization GO:0051236 3 0.015
membrane hyperpolarization GO:0060081 1 0.015
response to drug GO:0042493 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
protein acylation GO:0043543 3 0.015
spermatid differentiation GO:0048515 2 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
multicellular organismal signaling GO:0035637 22 0.015
branching morphogenesis of a nerve GO:0048755 4 0.015
ion homeostasis GO:0050801 41 0.015
neuron differentiation GO:0030182 353 0.015
response to chemical GO:0042221 320 0.014
behavior GO:0007610 74 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
system process GO:0003008 185 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
Human Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.014
spermatid development GO:0007286 2 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
Human Mouse
purine ribonucleotide biosynthetic process GO:0009152 20 0.014
brain development GO:0007420 293 0.014
response to wounding GO:0009611 116 0.014
metal ion transport GO:0030001 58 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
rna biosynthetic process GO:0032774 181 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
glycosyl compound metabolic process GO:1901657 11 0.013
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
cellular response to oxygen levels GO:0071453 1 0.013
cellular amine metabolic process GO:0044106 2 0.013
regulation of muscle contraction GO:0006937 3 0.013
muscle cell development GO:0055001 115 0.013
regulation of oxidative stress induced cell death GO:1903201 2 0.013
organophosphate biosynthetic process GO:0090407 23 0.013
regulation of cell communication GO:0010646 232 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.012
fatty acid transport GO:0015908 1 0.012
heart contraction GO:0060047 71 0.012
regulation of metabolic process GO:0019222 359 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
striated muscle cell development GO:0055002 108 0.012
negative regulation of gene expression GO:0010629 65 0.012
regulation of apoptotic process GO:0042981 98 0.012
neurotransmitter secretion GO:0007269 2 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
regulation of blood pressure GO:0008217 1 0.012
nucleoside triphosphate metabolic process GO:0009141 9 0.012
Human Mouse
protein homooligomerization GO:0051260 3 0.012
single organism organelle organization GO:1902589 199 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.012
striated muscle cell differentiation GO:0051146 129 0.012
negative regulation of catabolic process GO:0009895 3 0.012
glucose homeostasis GO:0042593 1 0.011
negative regulation of kinase activity GO:0033673 4 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.011
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.011
positive regulation of biological process GO:0048518 253 0.011
cellular component morphogenesis GO:0032989 336 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.011
single organism transport GO:0044765 206 0.011
Mouse
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.011
cytoskeleton organization GO:0007010 96 0.011
regulation of cell death GO:0010941 103 0.011
apoptotic process involved in morphogenesis GO:0060561 2 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of protein binding GO:0043393 3 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
protein localization to nucleus GO:0034504 3 0.011
single organism nuclear import GO:1902593 3 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of cell activation GO:0050865 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
apoptotic process involved in development GO:1902742 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
regulation of signal transduction GO:0009966 225 0.011
cellular catabolic process GO:0044248 27 0.011
Human Mouse
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.011
regulation of developmental process GO:0050793 247 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
protein complex subunit organization GO:0071822 46 0.011
oocyte maturation GO:0001556 4 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
organic cyclic compound catabolic process GO:1901361 15 0.010
Human Mouse
membrane repolarization GO:0086009 2 0.010
cellular response to oxygen radical GO:0071450 2 0.010
posttranscriptional gene silencing GO:0016441 3 0.010
sensory organ development GO:0007423 393 0.010
regulation of protein catabolic process GO:0042176 1 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
ribonucleoside biosynthetic process GO:0042455 2 0.010
circulatory system process GO:0003013 87 0.010
response to decreased oxygen levels GO:0036293 25 0.010

atp5a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.245
disease of metabolism DOID:0014667 0 0.155
mitochondrial metabolism disease DOID:700 0 0.155
inherited metabolic disorder DOID:655 0 0.155
leigh disease DOID:3652 0 0.039
nervous system disease DOID:863 0 0.037
muscular disease DOID:0080000 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscle tissue disease DOID:66 0 0.020
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017
cardiovascular system disease DOID:1287 0 0.016
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.015
myopathy DOID:423 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013