Danio rerio

0 known processes

helt

hey-like transcription factor

(Aliases: zgc:109704)

helt biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.670
Zebrafish Mouse
central nervous system development GO:0007417 387 0.426
Zebrafish Mouse
cellular response to external stimulus GO:0071496 2 0.348
localization of cell GO:0051674 244 0.310
chordate embryonic development GO:0043009 271 0.302
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.218
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.197
Zebrafish Mouse
single organism transport GO:0044765 206 0.188
negative regulation of biological process GO:0048519 304 0.174
Zebrafish Mouse
cell motility GO:0048870 244 0.158
cellular component movement GO:0006928 335 0.145
biosynthetic process GO:0009058 294 0.142
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.140
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.139
Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.135
Zebrafish
negative regulation of cellular process GO:0048523 283 0.134
Zebrafish Mouse
locomotion GO:0040011 313 0.131
larval development GO:0002164 2 0.128
regulation of cell death GO:0010941 103 0.128
establishment of localization GO:0051234 244 0.128
transport GO:0006810 220 0.125
regulation of nitrogen compound metabolic process GO:0051171 251 0.124
Zebrafish Mouse
response to amine GO:0014075 1 0.123
tube morphogenesis GO:0035239 349 0.123
eye morphogenesis GO:0048592 144 0.122
regulation of macromolecule metabolic process GO:0060255 317 0.122
Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.121
Zebrafish Mouse
sprouting angiogenesis GO:0002040 53 0.120
adult behavior GO:0030534 2 0.120
programmed cell death GO:0012501 119 0.119
cellular aromatic compound metabolic process GO:0006725 295 0.114
Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.113
Zebrafish Mouse
death GO:0016265 121 0.111
cellular macromolecule biosynthetic process GO:0034645 224 0.110
Zebrafish Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.110
neuron development GO:0048666 262 0.107
phagocytosis GO:0006909 3 0.106
regulation of macromolecule biosynthetic process GO:0010556 225 0.106
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.106
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.102
Mouse
aging GO:0007568 2 0.098
Mouse
amine metabolic process GO:0009308 2 0.096
cellular component assembly GO:0022607 170 0.096
transcription dna templated GO:0006351 181 0.096
Zebrafish Mouse
cell part morphogenesis GO:0032990 246 0.094
muscle organ development GO:0007517 101 0.092
nitrogen compound metabolic process GO:0006807 319 0.091
Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.091
Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.090
catecholamine metabolic process GO:0006584 2 0.090
digestive tract morphogenesis GO:0048546 231 0.088
vasculature development GO:0001944 278 0.087
Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.086
positive regulation of biological process GO:0048518 253 0.085
Mouse
response to stress GO:0006950 263 0.084
positive regulation of cell cycle GO:0045787 3 0.082
cellular macromolecule metabolic process GO:0044260 391 0.081
Zebrafish Mouse
cellular response to extracellular stimulus GO:0031668 2 0.081
cellular component morphogenesis GO:0032989 336 0.080
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.079
blood vessel morphogenesis GO:0048514 216 0.078
Zebrafish
regulation of metal ion transport GO:0010959 4 0.076
embryonic organ development GO:0048568 381 0.073
regulation of primary metabolic process GO:0080090 311 0.072
Zebrafish Mouse
organic substance biosynthetic process GO:1901576 289 0.072
Zebrafish Mouse
guanosine containing compound metabolic process GO:1901068 4 0.072
cellular component biogenesis GO:0044085 178 0.071
sensory organ development GO:0007423 393 0.070
apoptotic process GO:0006915 116 0.069
cellular protein catabolic process GO:0044257 4 0.069
regulation of biosynthetic process GO:0009889 250 0.069
Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.069
epithelial cell differentiation GO:0030855 116 0.068
Zebrafish
negative regulation of cell death GO:0060548 60 0.068
organic cyclic compound metabolic process GO:1901360 301 0.068
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.066
Zebrafish Mouse
regulation of transcription dna templated GO:0006355 213 0.066
Zebrafish Mouse
head development GO:0060322 303 0.065
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.064
Zebrafish Mouse
cellular amine metabolic process GO:0044106 2 0.063
regulation of programmed cell death GO:0043067 101 0.063
heterocycle metabolic process GO:0046483 290 0.063
Zebrafish Mouse
growth GO:0040007 174 0.062
Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.061
regulation of cellular biosynthetic process GO:0031326 245 0.060
Zebrafish Mouse
brain development GO:0007420 293 0.060
Zebrafish
gtp metabolic process GO:0046039 4 0.059
single organism organelle organization GO:1902589 199 0.059
guanosine containing compound catabolic process GO:1901069 2 0.058
regulation of rna biosynthetic process GO:2001141 213 0.058
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.058
nephron morphogenesis GO:0072028 2 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
regulation of gene expression GO:0010468 265 0.055
Zebrafish Mouse
cellular ketone metabolic process GO:0042180 11 0.055
gene expression GO:0010467 252 0.054
Zebrafish Mouse
morphogenesis of an epithelium GO:0002009 333 0.053
cellular biosynthetic process GO:0044249 286 0.053
Zebrafish Mouse
stem cell maintenance GO:0019827 4 0.052
angiogenesis GO:0001525 158 0.052
axonogenesis GO:0007409 152 0.051
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
cell migration GO:0016477 237 0.051
regulation of rna metabolic process GO:0051252 224 0.050
Zebrafish Mouse
organelle organization GO:0006996 227 0.048
positive regulation of cellular metabolic process GO:0031325 94 0.048
Mouse
striated muscle tissue development GO:0014706 110 0.047
protein modification process GO:0036211 100 0.047
cellular protein metabolic process GO:0044267 129 0.047
regionalization GO:0003002 274 0.046
Zebrafish
protein metabolic process GO:0019538 183 0.045
regulation of stem cell proliferation GO:0072091 2 0.045
establishment of protein localization to organelle GO:0072594 4 0.045
single organism localization GO:1902578 225 0.045
gtp catabolic process GO:0006184 2 0.044
epithelial tube morphogenesis GO:0060562 148 0.044
small molecule metabolic process GO:0044281 77 0.044
positive regulation of metabolic process GO:0009893 108 0.044
Mouse
stem cell proliferation GO:0072089 4 0.044
regulation of reproductive process GO:2000241 4 0.043
single organism metabolic process GO:0044710 217 0.043
response to external stimulus GO:0009605 264 0.043
maintenance of location GO:0051235 4 0.043
sensory perception of pain GO:0019233 1 0.043
modification dependent macromolecule catabolic process GO:0043632 3 0.043
cell projection morphogenesis GO:0048858 244 0.043
response to drug GO:0042493 3 0.041
positive regulation of cell activation GO:0050867 1 0.041
regulation of catalytic activity GO:0050790 55 0.041
regulation of establishment of protein localization GO:0070201 4 0.041
rna metabolic process GO:0016070 219 0.041
Zebrafish Mouse
regulation of apoptotic process GO:0042981 98 0.040
protein import GO:0017038 3 0.040
ubiquitin dependent protein catabolic process GO:0006511 3 0.039
meiotic nuclear division GO:0007126 4 0.039
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.039
Zebrafish Mouse
regulation of cell activation GO:0050865 1 0.038
multi organism process GO:0051704 134 0.038
Mouse
response to amphetamine GO:0001975 1 0.038
positive regulation of cellular amine metabolic process GO:0033240 0 0.038
modification dependent protein catabolic process GO:0019941 3 0.038
regulation of protein metabolic process GO:0051246 56 0.037
extrinsic apoptotic signaling pathway GO:0097191 3 0.037
cellular response to nutrient levels GO:0031669 2 0.037
regulation of cellular ketone metabolic process GO:0010565 7 0.037
catechol containing compound metabolic process GO:0009712 2 0.036
oxoacid metabolic process GO:0043436 31 0.036
ion transport GO:0006811 114 0.036
gastrulation GO:0007369 208 0.036
skeletal system development GO:0001501 181 0.036
blood vessel development GO:0001568 246 0.035
Zebrafish
protein targeting to nucleus GO:0044744 3 0.035
protein localization to nucleus GO:0034504 3 0.035
regulation of nucleoside metabolic process GO:0009118 2 0.035
muscle structure development GO:0061061 196 0.035
positive regulation of catabolic process GO:0009896 4 0.034
regulation of gtp catabolic process GO:0033124 2 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.033
cellular response to stress GO:0033554 62 0.033
positive regulation of cellular process GO:0048522 201 0.032
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.032
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
Zebrafish Mouse
positive regulation of transport GO:0051050 2 0.032
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
Zebrafish Mouse
cell death GO:0008219 121 0.031
digestive tract development GO:0048565 265 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
cell projection organization GO:0030030 284 0.031
negative regulation of response to stimulus GO:0048585 104 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
camera type eye morphogenesis GO:0048593 108 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.030
muscle tissue development GO:0060537 110 0.030
organic acid metabolic process GO:0006082 31 0.030
skeletal muscle organ development GO:0060538 78 0.030
system process GO:0003008 185 0.030
digestive system development GO:0055123 289 0.030
nucleic acid metabolic process GO:0090304 244 0.030
Zebrafish Mouse
hemopoiesis GO:0030097 183 0.029
renal system development GO:0072001 94 0.029
erk1 and erk2 cascade GO:0070371 4 0.029
regulation of epithelial cell proliferation GO:0050678 3 0.029
membrane invagination GO:0010324 1 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.029
regulation of neurogenesis GO:0050767 87 0.029
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.029
Mouse
negative regulation of nuclear division GO:0051784 3 0.028
cation transport GO:0006812 81 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
positive regulation of molecular function GO:0044093 33 0.028
regulation of intracellular signal transduction GO:1902531 57 0.027
response to other organism GO:0051707 97 0.027
positive regulation of nucleoside metabolic process GO:0045979 1 0.027
regulation of phosphorus metabolic process GO:0051174 43 0.027
positive regulation of gene expression GO:0010628 71 0.027
Mouse
central nervous system neuron differentiation GO:0021953 74 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
Zebrafish Mouse
lymphocyte proliferation GO:0046651 1 0.027
regulation of localization GO:0032879 104 0.027
phosphorus metabolic process GO:0006793 109 0.027
positive regulation of gtpase activity GO:0043547 1 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
phosphorylation GO:0016310 69 0.026
anterior posterior pattern specification GO:0009952 152 0.026
Zebrafish
nuclear transport GO:0051169 4 0.026
regulation of binding GO:0051098 3 0.026
nuclear import GO:0051170 3 0.026
signal transduction GO:0007165 455 0.026
Zebrafish
response to decreased oxygen levels GO:0036293 25 0.026
negative regulation of metabolic process GO:0009892 86 0.026
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.026
Mouse
camera type eye development GO:0043010 222 0.026
intracellular signal transduction GO:0035556 85 0.025
regulation of gtpase activity GO:0043087 2 0.025
gland development GO:0048732 143 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
neuron projection development GO:0031175 180 0.025
single organism nuclear import GO:1902593 3 0.025
lateral line development GO:0048882 66 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of signaling GO:0023051 235 0.025
negative regulation of biosynthetic process GO:0009890 55 0.025
Zebrafish Mouse
neural crest cell development GO:0014032 62 0.025
neurological system process GO:0050877 62 0.025
negative regulation of catabolic process GO:0009895 3 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
Mouse
leukocyte proliferation GO:0070661 1 0.024
regulation of protein catabolic process GO:0042176 1 0.024
response to chemical GO:0042221 320 0.024
phosphate containing compound metabolic process GO:0006796 108 0.023
regulation of protein transport GO:0051223 3 0.023
protein acylation GO:0043543 3 0.023
peptidyl lysine acetylation GO:0018394 2 0.023
macromolecule modification GO:0043412 111 0.023
protein import into nucleus GO:0006606 3 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
regulation of biological quality GO:0065008 263 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
Zebrafish
interspecies interaction between organisms GO:0044419 4 0.023
regulation of phosphate metabolic process GO:0019220 43 0.023
positive regulation of leukocyte differentiation GO:1902107 1 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
cellular protein modification process GO:0006464 100 0.023
negative regulation of gene expression GO:0010629 65 0.022
Zebrafish Mouse
regulation of synaptic plasticity GO:0048167 1 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.022
Zebrafish Mouse
neuron projection morphogenesis GO:0048812 161 0.022
meiotic cell cycle process GO:1903046 3 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
Mouse
response to biotic stimulus GO:0009607 97 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
Zebrafish Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.022
positive regulation of response to stimulus GO:0048584 80 0.022
ameboidal type cell migration GO:0001667 143 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
eye development GO:0001654 277 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
dopaminergic neuron differentiation GO:0071542 14 0.021
locomotory behavior GO:0007626 34 0.021
segmentation GO:0035282 97 0.021
Zebrafish
cellular response to starvation GO:0009267 1 0.021
positive regulation of transcription dna templated GO:0045893 57 0.021
Mouse
regulation of cell shape GO:0008360 1 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
Zebrafish Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.021
Zebrafish
cell substrate adhesion GO:0031589 4 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
g protein coupled receptor signaling pathway GO:0007186 74 0.020
somitogenesis GO:0001756 87 0.020
Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
photoreceptor cell differentiation GO:0046530 55 0.020
regulation of dendrite development GO:0050773 3 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
circulatory system process GO:0003013 87 0.020
positive regulation of rna biosynthetic process GO:1902680 57 0.019
Mouse
response to abiotic stimulus GO:0009628 122 0.019
regulation of developmental process GO:0050793 247 0.019
Zebrafish
negative regulation of protein complex assembly GO:0031333 1 0.019
determination of bilateral symmetry GO:0009855 204 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.019
Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
protein phosphorylation GO:0006468 47 0.019
regulation of calcium ion transport GO:0051924 2 0.019
calcium ion transport into cytosol GO:0060402 3 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
positive regulation of cell differentiation GO:0045597 30 0.019
regulation of protein complex assembly GO:0043254 3 0.019
lipid storage GO:0019915 1 0.019
protein secretion GO:0009306 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
cell proliferation GO:0008283 80 0.018
connective tissue development GO:0061448 99 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
Zebrafish Mouse
neural crest cell migration GO:0001755 42 0.018
urogenital system development GO:0001655 97 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
regulation of molecular function GO:0065009 70 0.018
regulation of cellular component organization GO:0051128 86 0.018
metal ion transport GO:0030001 58 0.018
positive regulation of immune effector process GO:0002699 3 0.017
phagocytosis engulfment GO:0006911 1 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
somite development GO:0061053 96 0.017
Zebrafish
regulation of organ growth GO:0046620 3 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
inner ear morphogenesis GO:0042472 63 0.017
sensory organ morphogenesis GO:0090596 200 0.017
diencephalon development GO:0021536 58 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
fin development GO:0033333 77 0.017
positive regulation of protein metabolic process GO:0051247 23 0.017
organic substance transport GO:0071702 58 0.017
neuromast development GO:0048884 46 0.017
tissue remodeling GO:0048771 4 0.017
response to external biotic stimulus GO:0043207 97 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
autonomic nervous system development GO:0048483 19 0.016
axon development GO:0061564 166 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
endoderm development GO:0007492 49 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
multi organism cellular process GO:0044764 2 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
Mouse
sequestering of calcium ion GO:0051208 3 0.016
establishment of endothelial barrier GO:0061028 3 0.016
germ line stem cell maintenance GO:0030718 2 0.016
response to endogenous stimulus GO:0009719 83 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
Zebrafish Mouse
transmembrane transport GO:0055085 120 0.016
retina development in camera type eye GO:0060041 146 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
Zebrafish Mouse
protein acetylation GO:0006473 2 0.016
regulation of cell differentiation GO:0045595 142 0.016
Zebrafish
regulation of signal transduction GO:0009966 225 0.015
regulation of cell motility GO:2000145 46 0.015
sensory system development GO:0048880 76 0.015
regulation of cell communication GO:0010646 232 0.015
negative regulation of mitosis GO:0045839 3 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
cellular localization GO:0051641 97 0.015
regulation of transport GO:0051049 45 0.015
response to organic substance GO:0010033 153 0.015
negative regulation of developmental process GO:0051093 65 0.015
Zebrafish
ear development GO:0043583 127 0.015
kidney development GO:0001822 92 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
response to hexose GO:0009746 3 0.015
cell cycle arrest GO:0007050 1 0.015
neurotransmitter secretion GO:0007269 2 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.014
peptidyl serine modification GO:0018209 2 0.014
regulation of immune system process GO:0002682 34 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
neurotransmitter transport GO:0006836 2 0.014
positive regulation of catalytic activity GO:0043085 25 0.014
lens fiber cell development GO:0070307 3 0.014
skeletal muscle tissue development GO:0007519 67 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
mitochondrion organization GO:0007005 4 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
sequestering of metal ion GO:0051238 3 0.014
positive regulation of ras gtpase activity GO:0032320 1 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
Zebrafish Mouse
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
glucose import GO:0046323 2 0.014
positive regulation of cell division GO:0051781 2 0.014
transmission of nerve impulse GO:0019226 19 0.014
protein stabilization GO:0050821 2 0.014
immune system development GO:0002520 191 0.013
forebrain development GO:0030900 96 0.013
positive regulation of synapse assembly GO:0051965 1 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
taxis GO:0042330 109 0.013
specification of symmetry GO:0009799 204 0.013
exocytosis GO:0006887 1 0.013
regulation of mesenchymal cell proliferation GO:0010464 1 0.013
spermatid development GO:0007286 2 0.013
mesoderm development GO:0007498 88 0.013
compound eye development GO:0048749 2 0.013
stem cell development GO:0048864 82 0.013
multicellular organism growth GO:0035264 4 0.013
Mouse
neuroblast proliferation GO:0007405 2 0.013
regulation of phosphorylation GO:0042325 26 0.013
adherens junction organization GO:0034332 4 0.013
response to corticosteroid GO:0031960 1 0.013
cartilage development GO:0051216 96 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
stem cell differentiation GO:0048863 117 0.013
positive regulation of histone modification GO:0031058 1 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of ion transport GO:0043269 22 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
negative regulation of neural precursor cell proliferation GO:2000178 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.012
bone remodeling GO:0046849 2 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
developmental maturation GO:0021700 34 0.012
lateral line system development GO:0048925 76 0.012
positive regulation of developmental process GO:0051094 50 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
Mouse
regulation of stem cell differentiation GO:2000736 4 0.012
autophagy GO:0006914 4 0.012
positive regulation of cellular protein metabolic process GO:0032270 22 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
neuropeptide signaling pathway GO:0007218 11 0.012
cell maturation GO:0048469 23 0.012
determination of left right symmetry GO:0007368 179 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
multicellular organismal response to stress GO:0033555 2 0.012
multi organism reproductive process GO:0044703 36 0.012
protein complex subunit organization GO:0071822 46 0.012
mononuclear cell proliferation GO:0032943 1 0.012
epithelial cell migration GO:0010631 25 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of hydrolase activity GO:0051336 28 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
peptide metabolic process GO:0006518 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
ion transmembrane transport GO:0034220 91 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
purine containing compound metabolic process GO:0072521 29 0.011
cognition GO:0050890 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
Zebrafish
post embryonic morphogenesis GO:0009886 4 0.011
microtubule based process GO:0007017 60 0.011
cellular response to toxic substance GO:0097237 1 0.011
mesoderm morphogenesis GO:0048332 51 0.011
spinal cord development GO:0021510 46 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
regulation of lipid transport GO:0032368 4 0.011
blood circulation GO:0008015 87 0.011
response to uv GO:0009411 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
cytoskeleton organization GO:0007010 96 0.011
response to oxygen levels GO:0070482 25 0.011
regulation of neuron differentiation GO:0045664 56 0.011
negative regulation of kinase activity GO:0033673 4 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
Zebrafish Mouse
response to inorganic substance GO:0010035 38 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
regulation of transporter activity GO:0032409 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
embryonic heart tube development GO:0035050 133 0.011
neuron death GO:0070997 21 0.011
regulation of system process GO:0044057 40 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of protein phosphorylation GO:0001932 18 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
Zebrafish Mouse
wnt signaling pathway GO:0016055 80 0.010
somatic stem cell maintenance GO:0035019 1 0.010
divalent metal ion transport GO:0070838 20 0.010
immune response GO:0006955 28 0.010
central nervous system neuron axonogenesis GO:0021955 18 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
positive regulation of programmed cell death GO:0043068 29 0.010
heart development GO:0007507 313 0.010
Zebrafish
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
negative regulation of cell communication GO:0010648 96 0.010
phenol containing compound biosynthetic process GO:0046189 4 0.010
response to bacterium GO:0009617 58 0.010
positive regulation of secretion GO:0051047 1 0.010
ras protein signal transduction GO:0007265 7 0.010
developmental growth GO:0048589 166 0.010
regulation of tube size GO:0035150 2 0.010
neural crest cell differentiation GO:0014033 72 0.010
single organism reproductive process GO:0044702 40 0.010
cytoplasm organization GO:0007028 4 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
immune system process GO:0002376 241 0.010

helt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.034
disease of metabolism DOID:0014667 0 0.019