Danio rerio

15 known processes

krt5

keratin 5

(Aliases: ckii,wu:fb02h09,MGC77647,wu:fk78b12,zfCKII,wu:fj02d02)

krt5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of water loss via skin GO:0033561 1 0.785
Mouse
multicellular organismal water homeostasis GO:0050891 1 0.452
Mouse
keratinocyte differentiation GO:0030216 0 0.383
Mouse
regulation of sodium ion transport GO:0002028 2 0.304
phagocytosis GO:0006909 3 0.295
regulation of biological quality GO:0065008 263 0.280
Human Mouse
anion transport GO:0006820 38 0.252
wound healing GO:0042060 90 0.234
water homeostasis GO:0030104 4 0.206
Mouse
growth GO:0040007 174 0.203
cognition GO:0050890 1 0.201
desmosome organization GO:0002934 3 0.188
stem cell maintenance GO:0019827 4 0.165
skin development GO:0043588 54 0.164
Mouse
regulation of establishment of protein localization GO:0070201 4 0.162
negative regulation of protein transport GO:0051224 3 0.158
transport GO:0006810 220 0.156
ion transport GO:0006811 114 0.150
establishment of localization GO:0051234 244 0.148
extrinsic apoptotic signaling pathway GO:0097191 3 0.142
Mouse
fatty acid transport GO:0015908 1 0.132
monovalent inorganic cation transport GO:0015672 42 0.131
desmosome assembly GO:0002159 2 0.125
gastrulation GO:0007369 208 0.123
homeostatic process GO:0042592 142 0.121
Human Mouse
apoptotic process GO:0006915 116 0.119
Mouse
negative regulation of mesoderm development GO:2000381 5 0.116
response to corticosteroid GO:0031960 1 0.104
digestive tract development GO:0048565 265 0.103
plasma membrane repair GO:0001778 2 0.102
circadian sleep wake cycle GO:0042745 2 0.101
protein secretion GO:0009306 1 0.100
tissue remodeling GO:0048771 4 0.099
ectodermal cell fate specification GO:0001715 2 0.095
membrane invagination GO:0010324 1 0.095
signal transduction GO:0007165 455 0.094
Mouse
heart development GO:0007507 313 0.092
gastrulation with mouth forming second GO:0001702 44 0.092
regulation of apoptotic process GO:0042981 98 0.091
positive regulation of transport GO:0051050 2 0.090
regulation of metal ion transport GO:0010959 4 0.089
response to stress GO:0006950 263 0.088
response to wounding GO:0009611 116 0.088
cell death GO:0008219 121 0.086
Mouse
regulation of eye photoreceptor cell development GO:0042478 2 0.086
larval development GO:0002164 2 0.084
intestinal absorption GO:0050892 2 0.084
programmed cell death GO:0012501 119 0.082
Mouse
positive regulation of cell cycle GO:0045787 3 0.082
epidermis development GO:0008544 48 0.080
Mouse
morphogenesis of an epithelium GO:0002009 333 0.077
Mouse
regulation of programmed cell death GO:0043067 101 0.077
regulation of circadian rhythm GO:0042752 4 0.075
regulation of cytokine production GO:0001817 3 0.068
polyol transport GO:0015791 7 0.066
sensory system development GO:0048880 76 0.065
phagocytosis engulfment GO:0006911 1 0.065
lateral line system development GO:0048925 76 0.065
establishment of endothelial barrier GO:0061028 3 0.064
regulation of epithelial cell proliferation GO:0050678 3 0.064
Mouse
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.062
tube morphogenesis GO:0035239 349 0.062
protein polymerization GO:0051258 4 0.062
regeneration GO:0031099 91 0.061
monocarboxylic acid transport GO:0015718 5 0.061
epiboly GO:0090504 41 0.061
proximal distal pattern formation GO:0009954 1 0.060
morphogenesis of an epithelial sheet GO:0002011 49 0.060
cell motility GO:0048870 244 0.059
developmental growth GO:0048589 166 0.058
tissue regeneration GO:0042246 74 0.056
nuclear transport GO:0051169 4 0.055
regulation of locomotion GO:0040012 55 0.055
lymphocyte differentiation GO:0030098 9 0.055
aging GO:0007568 2 0.055
cellular macromolecule metabolic process GO:0044260 391 0.053
single organism nuclear import GO:1902593 3 0.053
establishment of protein localization to organelle GO:0072594 4 0.053
determination of bilateral symmetry GO:0009855 204 0.052
digestive system development GO:0055123 289 0.051
system process GO:0003008 185 0.051
regulation of dna templated transcription in response to stress GO:0043620 0 0.051
organic substance transport GO:0071702 58 0.050
regulation of epidermis development GO:0045682 2 0.050
Mouse
long chain fatty acid transport GO:0015909 1 0.050
cellular protein modification process GO:0006464 100 0.050
hematopoietic or lymphoid organ development GO:0048534 191 0.050
Mouse
death GO:0016265 121 0.049
Mouse
maintenance of location GO:0051235 4 0.049
regulation of protein polymerization GO:0032271 2 0.048
cellular response to starvation GO:0009267 1 0.047
single organism transport GO:0044765 206 0.047
gene expression GO:0010467 252 0.047
regulation of protein transport GO:0051223 3 0.047
organelle organization GO:0006996 227 0.046
Human Mouse Rat
heterocycle metabolic process GO:0046483 290 0.046
cellular response to external stimulus GO:0071496 2 0.046
digestive tract morphogenesis GO:0048546 231 0.045
cellular nitrogen compound metabolic process GO:0034641 290 0.044
response to abiotic stimulus GO:0009628 122 0.044
Rat
positive regulation of cellular process GO:0048522 201 0.043
chemical homeostasis GO:0048878 49 0.043
Mouse
protein localization to nucleus GO:0034504 3 0.042
protein import into nucleus GO:0006606 3 0.041
mesenchyme development GO:0060485 127 0.041
protein import GO:0017038 3 0.041
regulation of gene expression GO:0010468 265 0.041
fin regeneration GO:0031101 51 0.040
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.038
neuroblast differentiation GO:0014016 1 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.036
Mouse
negative regulation of cytokine production GO:0001818 1 0.036
regulation of response to extracellular stimulus GO:0032104 1 0.036
single organism membrane fusion GO:0044801 2 0.036
single organism localization GO:1902578 225 0.036
neutrophil homeostasis GO:0001780 1 0.036
cation transport GO:0006812 81 0.035
regulation of circadian sleep wake cycle GO:0042749 1 0.035
nucleocytoplasmic transport GO:0006913 4 0.035
organic anion transport GO:0015711 15 0.035
protein targeting to nucleus GO:0044744 3 0.034
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
negative regulation of cellular catabolic process GO:0031330 3 0.033
cell cycle g1 s phase transition GO:0044843 1 0.033
epidermal cell differentiation GO:0009913 36 0.033
Mouse
negative regulation of defense response GO:0031348 2 0.032
Mouse
regulation of protein complex assembly GO:0043254 3 0.032
protein metabolic process GO:0019538 183 0.032
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.032
sleep GO:0030431 1 0.032
regulation of ectoderm development GO:2000383 2 0.032
regulation of rna metabolic process GO:0051252 224 0.031
regulation of protein ubiquitination GO:0031396 3 0.031
negative regulation of multicellular organismal process GO:0051241 69 0.031
circadian sleep wake cycle sleep GO:0050802 1 0.031
heart looping GO:0001947 94 0.031
lipid storage GO:0019915 1 0.030
cell cycle GO:0007049 93 0.030
regionalization GO:0003002 274 0.030
response to uv GO:0009411 3 0.030
autophagy GO:0006914 4 0.030
regulation of protein import into nucleus GO:0042306 2 0.030
regulation of cell motility GO:2000145 46 0.030
regulation of protein targeting GO:1903533 2 0.029
gtp metabolic process GO:0046039 4 0.029
specification of symmetry GO:0009799 204 0.029
neural crest cell development GO:0014032 62 0.029
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.029
transcription dna templated GO:0006351 181 0.028
sodium ion transport GO:0006814 24 0.028
regulation of mesoderm development GO:2000380 11 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
cellular response to extracellular stimulus GO:0031668 2 0.027
actin filament polymerization GO:0030041 2 0.027
epithelial cell development GO:0002064 42 0.027
regulation of localization GO:0032879 104 0.026
regulation of photoreceptor cell differentiation GO:0046532 2 0.026
regulation of mitotic cell cycle phase transition GO:1901990 8 0.026
locomotion GO:0040011 313 0.025
metal ion transport GO:0030001 58 0.025
biosynthetic process GO:0009058 294 0.025
actin polymerization or depolymerization GO:0008154 2 0.025
cellular component movement GO:0006928 335 0.025
regulation of cell death GO:0010941 103 0.025
positive regulation of catabolic process GO:0009896 4 0.025
stem cell development GO:0048864 82 0.025
negative regulation of cellular process GO:0048523 283 0.024
Mouse
nitrogen compound metabolic process GO:0006807 319 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of organelle organization GO:0033043 29 0.024
ion transmembrane transport GO:0034220 91 0.024
cell cell adhesion involved in gastrulation GO:0070586 4 0.024
multi organism process GO:0051704 134 0.024
Mouse
lateral line development GO:0048882 66 0.024
negative regulation of nuclear division GO:0051784 3 0.024
oxoacid metabolic process GO:0043436 31 0.024
polarized epithelial cell differentiation GO:0030859 4 0.024
negative regulation of epithelial cell proliferation GO:0050680 1 0.023
Mouse
fatty acid biosynthetic process GO:0006633 4 0.023
localization of cell GO:0051674 244 0.023
cellular response to organic cyclic compound GO:0071407 38 0.023
calcium ion import GO:0070509 4 0.023
positive regulation of metabolic process GO:0009893 108 0.023
apoptotic signaling pathway GO:0097190 23 0.023
Mouse
behavior GO:0007610 74 0.022
intestinal cholesterol absorption GO:0030299 2 0.022
female sex differentiation GO:0046660 4 0.022
regulation of cell activation GO:0050865 1 0.022
regulation of cell differentiation GO:0045595 142 0.022
Mouse
positive regulation of cytoskeleton organization GO:0051495 3 0.022
ectoderm development GO:0007398 9 0.022
neuromast development GO:0048884 46 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
cytokinesis GO:0000910 3 0.022
cellular response to radiation GO:0071478 4 0.022
muscle cell development GO:0055001 115 0.022
Rat
regulation of immune system process GO:0002682 34 0.022
Human
neurological system process GO:0050877 62 0.022
determination of left right symmetry GO:0007368 179 0.021
zymogen activation GO:0031638 3 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
immune system process GO:0002376 241 0.021
Human Mouse
multicellular organism growth GO:0035264 4 0.021
organic acid transport GO:0015849 9 0.021
regulation of cellular component movement GO:0051270 55 0.021
negative regulation of mitosis GO:0045839 3 0.021
regulation of cell cycle phase transition GO:1901987 8 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
hemopoiesis GO:0030097 183 0.021
Mouse
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of cellular component organization GO:0051128 86 0.020
regulation of developmental process GO:0050793 247 0.020
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
meiotic nuclear division GO:0007126 4 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
cellular biosynthetic process GO:0044249 286 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
leukocyte homeostasis GO:0001776 2 0.020
regulation of inflammatory response GO:0050727 2 0.020
Mouse
lipid catabolic process GO:0016042 4 0.020
transmembrane transport GO:0055085 120 0.020
circadian rhythm GO:0007623 19 0.020
regulation of vesicle mediated transport GO:0060627 9 0.020
determination of heart left right asymmetry GO:0061371 117 0.019
embryonic organ development GO:0048568 381 0.019
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
cellular protein metabolic process GO:0044267 129 0.019
negative regulation of catabolic process GO:0009895 3 0.019
morphogenesis of an epithelial fold GO:0060571 1 0.019
regulation of actin filament based process GO:0032970 9 0.019
nucleic acid metabolic process GO:0090304 244 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
regulation of protein depolymerization GO:1901879 1 0.019
mesendoderm development GO:0048382 10 0.019
lipid digestion GO:0044241 3 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.018
protein modification process GO:0036211 100 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
organelle fusion GO:0048284 3 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
actin filament based movement GO:0030048 1 0.018
response to organic substance GO:0010033 153 0.018
Mouse
regulation of autophagy GO:0010506 3 0.018
negative regulation of response to stimulus GO:0048585 104 0.018
Mouse
nucleic acid templated transcription GO:0097659 181 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
gland development GO:0048732 143 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
organic substance biosynthetic process GO:1901576 289 0.017
hair cell differentiation GO:0035315 32 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
cellular component disassembly GO:0022411 1 0.017
positive regulation of apoptotic process GO:0043065 29 0.016
negative regulation of biological process GO:0048519 304 0.016
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
response to glucocorticoid GO:0051384 1 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
Mouse
regulation of transport GO:0051049 45 0.016
cell morphogenesis GO:0000902 289 0.016
leukocyte differentiation GO:0002521 25 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
innate immune response GO:0045087 13 0.016
Human
establishment of localization in cell GO:0051649 77 0.016
reciprocal dna recombination GO:0035825 1 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
ectoderm formation GO:0001705 2 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.015
response to light stimulus GO:0009416 46 0.015
brain development GO:0007420 293 0.015
actin filament based process GO:0030029 64 0.015
Rat
cellular localization GO:0051641 97 0.015
regulation of response to stimulus GO:0048583 269 0.015
Human Mouse
cellular component morphogenesis GO:0032989 336 0.015
Rat
chordate embryonic development GO:0043009 271 0.015
Mouse
regulation of response to nutrient levels GO:0032107 1 0.015
stem cell fate commitment GO:0048865 1 0.015
regulation of cellular component size GO:0032535 30 0.015
ear development GO:0043583 127 0.015
organic acid metabolic process GO:0006082 31 0.015
heart field specification GO:0003128 1 0.015
negative regulation of cell fate commitment GO:0010454 13 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
regulation of biosynthetic process GO:0009889 250 0.014
defense response GO:0006952 47 0.014
Human Mouse
regulation of cell projection assembly GO:0060491 4 0.014
membrane organization GO:0061024 21 0.014
heart morphogenesis GO:0003007 156 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
Mouse
protein complex subunit organization GO:0071822 46 0.014
Mouse
digestion GO:0007586 11 0.014
positive regulation of cell death GO:0010942 29 0.014
regulation of primary metabolic process GO:0080090 311 0.014
regulation of metabolic process GO:0019222 359 0.014
action potential GO:0001508 19 0.014
embryonic heart tube development GO:0035050 133 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
rna metabolic process GO:0016070 219 0.014
cell type specific apoptotic process GO:0097285 22 0.014
Mouse
macromolecule modification GO:0043412 111 0.014
nuclear import GO:0051170 3 0.013
atrioventricular valve formation GO:0003190 3 0.013
actin mediated cell contraction GO:0070252 1 0.013
urea transport GO:0015840 11 0.013
immune system development GO:0002520 191 0.013
Mouse
regulation of protein complex disassembly GO:0043244 1 0.013
post anal tail morphogenesis GO:0036342 19 0.013
cell aging GO:0007569 2 0.013
directional locomotion GO:0033058 1 0.013
inner ear receptor cell development GO:0060119 20 0.013
positive regulation of translation GO:0045727 1 0.013
developmental programmed cell death GO:0010623 4 0.013
organic hydroxy compound transport GO:0015850 14 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
response to drug GO:0042493 3 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of cell cycle process GO:0010564 20 0.012
cellular ketone metabolic process GO:0042180 11 0.012
regulation of myotube differentiation GO:0010830 2 0.012
response to carbohydrate GO:0009743 3 0.012
optic nerve morphogenesis GO:0021631 6 0.012
regulation of protein binding GO:0043393 3 0.012
protein complex disassembly GO:0043241 1 0.012
blood vessel development GO:0001568 246 0.012
response to steroid hormone GO:0048545 35 0.012
epithelial cell differentiation GO:0030855 116 0.012
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
digestive system process GO:0022600 9 0.012
regulation of gtpase activity GO:0043087 2 0.012
cellular response to organic substance GO:0071310 105 0.012
Mouse
positive regulation of hydrolase activity GO:0051345 13 0.012
cell adhesion GO:0007155 40 0.011
regulation of wound healing GO:0061041 2 0.011
pigment cell development GO:0070285 3 0.011
regulation of blood coagulation GO:0030193 1 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
cardiac cell fate commitment GO:0060911 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
insulin like growth factor receptor signaling pathway GO:0048009 4 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
myeloid cell homeostasis GO:0002262 56 0.011
carboxylic acid transport GO:0046942 8 0.011
positive regulation of protein depolymerization GO:1901881 1 0.011
vesicle mediated transport GO:0016192 22 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
mesodermal cell differentiation GO:0048333 21 0.011
t cell differentiation GO:0030217 6 0.011
intrinsic apoptotic signaling pathway GO:0097193 20 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
tube formation GO:0035148 25 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
regulation of muscle contraction GO:0006937 3 0.010
muscle structure development GO:0061061 196 0.010
Rat
regulation of hydrolase activity GO:0051336 28 0.010

krt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.048
disease of anatomical entity DOID:7 0 0.048
Human
musculoskeletal system disease DOID:17 0 0.048
disease of metabolism DOID:0014667 0 0.028
amyloidosis DOID:9120 0 0.014
acquired metabolic disease DOID:0060158 0 0.014