Danio rerio

0 known processes

znfl2a

zinc finger-like gene 2a

(Aliases: zgc:110491,sb:cb490,wu:fe16e10,znfl2,YF-458)

znfl2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 0.799
biosynthetic process GO:0009058 294 0.795
hematopoietic or lymphoid organ development GO:0048534 191 0.739
erythrocyte differentiation GO:0030218 54 0.711
erythrocyte homeostasis GO:0034101 55 0.624
immune system process GO:0002376 241 0.583
immune system development GO:0002520 191 0.581
aromatic compound biosynthetic process GO:0019438 217 0.574
heart process GO:0003015 71 0.570
organic cyclic compound metabolic process GO:1901360 301 0.545
hemopoiesis GO:0030097 183 0.523
organic substance biosynthetic process GO:1901576 289 0.513
regulation of primary metabolic process GO:0080090 311 0.509
regulation of cellular metabolic process GO:0031323 320 0.495
regulation of biosynthetic process GO:0009889 250 0.493
embryonic organ morphogenesis GO:0048562 274 0.487
cellular aromatic compound metabolic process GO:0006725 295 0.462
heart valve formation GO:0003188 4 0.457
regulation of macromolecule biosynthetic process GO:0010556 225 0.439
embryonic heart tube morphogenesis GO:0003143 108 0.438
regulation of metabolic process GO:0019222 359 0.417
larval development GO:0002164 2 0.403
cellular nitrogen compound biosynthetic process GO:0044271 218 0.396
digestive tract morphogenesis GO:0048546 231 0.374
tube morphogenesis GO:0035239 349 0.367
myeloid cell differentiation GO:0030099 86 0.363
positive regulation of metabolic process GO:0009893 108 0.350
regulation of transcription dna templated GO:0006355 213 0.348
embryonic hemopoiesis GO:0035162 53 0.326
regulation of cellular biosynthetic process GO:0031326 245 0.325
macromolecule biosynthetic process GO:0009059 227 0.324
transcription dna templated GO:0006351 181 0.321
regulation of nitrogen compound metabolic process GO:0051171 251 0.315
transcription from rna polymerase ii promoter GO:0006366 80 0.314
cardiogenic plate morphogenesis GO:0003142 1 0.287
heart looping GO:0001947 94 0.271
cardiac chamber formation GO:0003207 4 0.264
nucleobase containing compound metabolic process GO:0006139 274 0.255
regulation of rna biosynthetic process GO:2001141 213 0.254
cellular nitrogen compound metabolic process GO:0034641 290 0.251
cellular biosynthetic process GO:0044249 286 0.248
pancreas development GO:0031016 84 0.238
heterocycle biosynthetic process GO:0018130 215 0.231
heterocycle metabolic process GO:0046483 290 0.228
negative regulation of rna metabolic process GO:0051253 48 0.226
regulation of stem cell differentiation GO:2000736 4 0.214
erythrocyte development GO:0048821 24 0.213
heme metabolic process GO:0042168 9 0.212
regulation of macromolecule metabolic process GO:0060255 317 0.203
positive regulation of biosynthetic process GO:0009891 68 0.202
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.196
liver development GO:0001889 96 0.196
protein metabolic process GO:0019538 183 0.195
determination of bilateral symmetry GO:0009855 204 0.191
cellular macromolecule biosynthetic process GO:0034645 224 0.185
cardiac atrium morphogenesis GO:0003209 2 0.181
cellular protein metabolic process GO:0044267 129 0.179
morphogenesis of an epithelium GO:0002009 333 0.176
sensory organ morphogenesis GO:0090596 200 0.171
atrioventricular valve formation GO:0003190 3 0.163
cellular macromolecule metabolic process GO:0044260 391 0.163
cofactor biosynthetic process GO:0051188 10 0.161
determination of heart left right asymmetry GO:0061371 117 0.158
primitive hemopoiesis GO:0060215 27 0.156
somatic muscle development GO:0007525 4 0.154
positive regulation of endothelial cell differentiation GO:0045603 2 0.152
digestive tract development GO:0048565 265 0.150
embryonic skeletal system morphogenesis GO:0048704 93 0.147
primitive erythrocyte differentiation GO:0060319 5 0.145
gene expression GO:0010467 252 0.144
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.144
rhombomere formation GO:0021594 12 0.144
endocardium formation GO:0060214 1 0.138
erythrocyte maturation GO:0043249 8 0.134
macromolecule modification GO:0043412 111 0.133
pericardium development GO:0060039 1 0.130
positive regulation of cellular metabolic process GO:0031325 94 0.128
astrocyte differentiation GO:0048708 1 0.126
positive regulation of biological process GO:0048518 253 0.125
negative regulation of biosynthetic process GO:0009890 55 0.125
cell morphogenesis GO:0000902 289 0.122
mesodermal cell differentiation GO:0048333 21 0.119
eye development GO:0001654 277 0.119
embryonic heart tube development GO:0035050 133 0.118
negative regulation of cellular biosynthetic process GO:0031327 55 0.117
regulation of nucleic acid templated transcription GO:1903506 213 0.115
epithelial cell fate commitment GO:0072148 11 0.112
myeloid cell development GO:0061515 32 0.112
mesoderm morphogenesis GO:0048332 51 0.112
regulation of reproductive process GO:2000241 4 0.109
anterior posterior pattern specification GO:0009952 152 0.108
determination of left right symmetry GO:0007368 179 0.108
embryonic digestive tract morphogenesis GO:0048557 3 0.107
response to stress GO:0006950 263 0.106
negative regulation of mesodermal cell fate specification GO:0042662 3 0.104
organonitrogen compound metabolic process GO:1901564 74 0.103
nitrogen compound metabolic process GO:0006807 319 0.103
epithelial tube formation GO:0072175 19 0.103
embryo development ending in birth or egg hatching GO:0009792 271 0.103
positive regulation of epithelial cell differentiation GO:0030858 2 0.103
auditory receptor cell fate commitment GO:0009912 4 0.100
negative regulation of biological process GO:0048519 304 0.100
proepicardium development GO:0003342 4 0.099
muscle structure development GO:0061061 196 0.098
negative regulation of cellular process GO:0048523 283 0.098
stem cell differentiation GO:0048863 117 0.095
single organism metabolic process GO:0044710 217 0.093
regulation of response to stimulus GO:0048583 269 0.090
organic cyclic compound biosynthetic process GO:1901362 223 0.089
peripheral nervous system neuron axonogenesis GO:0048936 13 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.088
nucleic acid metabolic process GO:0090304 244 0.087
chordate embryonic development GO:0043009 271 0.086
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.086
heart development GO:0007507 313 0.086
single organism biosynthetic process GO:0044711 71 0.086
positive regulation of neuron migration GO:2001224 2 0.084
atrioventricular valve development GO:0003171 11 0.084
locomotion GO:0040011 313 0.083
muscle cell differentiation GO:0042692 139 0.082
convergent extension GO:0060026 118 0.081
myeloid cell homeostasis GO:0002262 56 0.080
generation of neurons GO:0048699 385 0.079
regulation of ectodermal cell fate specification GO:0042665 2 0.079
protein modification process GO:0036211 100 0.077
stem cell maintenance GO:0019827 4 0.077
ear morphogenesis GO:0042471 64 0.077
cardiac muscle cell differentiation GO:0055007 30 0.075
cellular protein modification process GO:0006464 100 0.075
regulation of cell differentiation GO:0045595 142 0.075
regulation of rna metabolic process GO:0051252 224 0.074
rhombomere development GO:0021546 19 0.073
mesodermal cell fate specification GO:0007501 12 0.073
specification of symmetry GO:0009799 204 0.072
cell cell recognition GO:0009988 1 0.071
negative regulation of transcription dna templated GO:0045892 45 0.071
skeletal system development GO:0001501 181 0.070
regulation of inner ear receptor cell differentiation GO:2000980 1 0.070
atrioventricular valve morphogenesis GO:0003181 6 0.069
sensory organ development GO:0007423 393 0.069
endocardium morphogenesis GO:0003160 4 0.068
cell fate commitment GO:0045165 99 0.068
cardiac muscle tissue development GO:0048738 48 0.067
peptide metabolic process GO:0006518 1 0.067
striated muscle cell differentiation GO:0051146 129 0.067
regulation of gene expression GO:0010468 265 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.065
signal transduction GO:0007165 455 0.065
homeostatic process GO:0042592 142 0.064
regulation of biological quality GO:0065008 263 0.064
peripheral nervous system development GO:0007422 55 0.063
negative regulation of nucleic acid templated transcription GO:1903507 45 0.062
ear development GO:0043583 127 0.062
intermediate mesoderm development GO:0048389 2 0.061
positive regulation of rna metabolic process GO:0051254 59 0.060
embryonic heart tube formation GO:0003144 1 0.059
heart morphogenesis GO:0003007 156 0.059
positive regulation of gene expression GO:0010628 71 0.059
rna biosynthetic process GO:0032774 181 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.058
cell morphogenesis involved in differentiation GO:0000904 195 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.057
epithelial tube morphogenesis GO:0060562 148 0.054
aging GO:0007568 2 0.054
positive regulation of macromolecule metabolic process GO:0010604 93 0.052
heart field specification GO:0003128 1 0.052
regulation of signaling GO:0023051 235 0.051
negative regulation of reproductive process GO:2000242 3 0.051
regulation of bone mineralization GO:0030500 2 0.050
establishment of localization GO:0051234 244 0.050
digestive system development GO:0055123 289 0.049
negative regulation of gene expression GO:0010629 65 0.048
rna metabolic process GO:0016070 219 0.048
developmental growth GO:0048589 166 0.048
inner ear development GO:0048839 126 0.048
single organism localization GO:1902578 225 0.048
retina layer formation GO:0010842 24 0.047
homeostasis of number of cells GO:0048872 62 0.047
endocrine pancreas development GO:0031018 27 0.046
maintenance of location GO:0051235 4 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.046
response to organic substance GO:0010033 153 0.045
regulation of binding GO:0051098 3 0.044
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.044
stem cell development GO:0048864 82 0.044
heart contraction GO:0060047 71 0.043
stem cell proliferation GO:0072089 4 0.043
camera type eye development GO:0043010 222 0.043
phosphorus metabolic process GO:0006793 109 0.043
axis specification GO:0009798 43 0.042
heart valve development GO:0003170 14 0.042
embryonic pattern specification GO:0009880 44 0.042
gastrulation with mouth forming second GO:0001702 44 0.042
positive regulation of cellular process GO:0048522 201 0.042
cranial nerve development GO:0021545 42 0.041
negative regulation of leukocyte differentiation GO:1902106 1 0.041
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.040
peripheral nervous system neuron differentiation GO:0048934 28 0.039
anterior posterior axis specification GO:0009948 20 0.039
negative regulation of macromolecule metabolic process GO:0010605 76 0.039
mesenchyme development GO:0060485 127 0.039
positive regulation of transcription dna templated GO:0045893 57 0.037
nuclear transport GO:0051169 4 0.037
regionalization GO:0003002 274 0.037
embryonic cranial skeleton morphogenesis GO:0048701 90 0.037
regulation of organ morphogenesis GO:2000027 35 0.035
positive regulation of stem cell proliferation GO:2000648 1 0.035
eye morphogenesis GO:0048592 144 0.035
cell cycle g2 m phase transition GO:0044839 4 0.034
multi organism process GO:0051704 134 0.034
epidermal cell fate specification GO:0009957 4 0.034
embryonic pectoral fin morphogenesis GO:0035118 24 0.034
hemangioblast cell differentiation GO:0060217 5 0.033
rhombomere 5 development GO:0021571 4 0.033
phosphate containing compound metabolic process GO:0006796 108 0.033
semicircular canal development GO:0060872 24 0.033
negative regulation of axon regeneration GO:0048681 4 0.033
positive regulation of jun kinase activity GO:0043507 2 0.032
nucleic acid templated transcription GO:0097659 181 0.032
septum transversum development GO:0003343 4 0.032
embryonic neurocranium morphogenesis GO:0048702 15 0.032
cardiac atrium development GO:0003230 4 0.032
regulation of translation GO:0006417 3 0.032
negative regulation of metabolic process GO:0009892 86 0.031
inner ear morphogenesis GO:0042472 63 0.031
hepaticobiliary system development GO:0061008 98 0.031
embryonic digestive tract development GO:0048566 4 0.030
gland development GO:0048732 143 0.030
protein phosphorylation GO:0006468 47 0.030
brain development GO:0007420 293 0.029
regulation of cell communication GO:0010646 232 0.029
protein targeting to nucleus GO:0044744 3 0.029
bmp signaling pathway GO:0030509 52 0.029
foregut morphogenesis GO:0007440 4 0.028
embryonic foregut morphogenesis GO:0048617 1 0.028
photoreceptor cell fate commitment GO:0046552 1 0.028
gastrulation GO:0007369 208 0.028
cellular response to stress GO:0033554 62 0.028
head development GO:0060322 303 0.027
convergent extension involved in gastrulation GO:0060027 71 0.027
cellular component morphogenesis GO:0032989 336 0.027
localization of cell GO:0051674 244 0.027
peripheral nervous system neuron development GO:0048935 22 0.027
dorsal aorta morphogenesis GO:0035912 3 0.026
axonogenesis GO:0007409 152 0.026
negative regulation of collateral sprouting GO:0048671 2 0.026
regulation of embryonic development GO:0045995 47 0.026
dna templated transcription initiation GO:0006352 1 0.026
chromosome organization GO:0051276 31 0.026
ventricular cardiac muscle cell development GO:0055015 5 0.026
inner ear receptor cell fate commitment GO:0060120 4 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
neuron projection morphogenesis GO:0048812 161 0.025
cell part morphogenesis GO:0032990 246 0.025
thyroid gland development GO:0030878 12 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.024
pharyngeal muscle development GO:0043282 4 0.024
cell migration GO:0016477 237 0.024
regulation of heart morphogenesis GO:2000826 17 0.024
regulation of catalytic activity GO:0050790 55 0.024
regulation of mechanoreceptor differentiation GO:0045631 1 0.024
blood vessel development GO:0001568 246 0.023
ectodermal placode development GO:0071696 37 0.023
vasculature development GO:0001944 278 0.023
mesoderm development GO:0007498 88 0.023
regulation of endothelial cell differentiation GO:0045601 3 0.022
forebrain development GO:0030900 96 0.022
translational initiation GO:0006413 3 0.022
organ formation GO:0048645 17 0.022
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
positive regulation of cellular biosynthetic process GO:0031328 68 0.022
programmed cell death GO:0012501 119 0.022
determination of intestine left right asymmetry GO:0071908 2 0.022
neuron development GO:0048666 262 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
regulation of ectoderm development GO:2000383 2 0.021
mechanoreceptor differentiation GO:0042490 37 0.021
response to oxygen containing compound GO:1901700 55 0.021
oocyte maturation GO:0001556 4 0.021
segmentation GO:0035282 97 0.021
thalamus development GO:0021794 6 0.021
formation of primary germ layer GO:0001704 62 0.021
small molecule metabolic process GO:0044281 77 0.020
endocrine system development GO:0035270 65 0.020
regulation of cellular protein metabolic process GO:0032268 52 0.020
heart valve morphogenesis GO:0003179 8 0.020
wound healing GO:0042060 90 0.020
epithelial cell differentiation GO:0030855 116 0.020
cell projection morphogenesis GO:0048858 244 0.020
phagocytosis GO:0006909 3 0.020
growth GO:0040007 174 0.020
otic vesicle morphogenesis GO:0071600 34 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
retina development in camera type eye GO:0060041 146 0.019
mesoderm formation GO:0001707 43 0.019
definitive hemopoiesis GO:0060216 18 0.019
positive regulation of embryonic development GO:0040019 3 0.019
response to external stimulus GO:0009605 264 0.019
cell cell signaling GO:0007267 52 0.019
organelle organization GO:0006996 227 0.019
phosphorylation GO:0016310 69 0.019
negative regulation of cell differentiation GO:0045596 46 0.018
lipid digestion GO:0044241 3 0.018
chromatin organization GO:0006325 22 0.018
primary neural tube formation GO:0014020 1 0.018
establishment of organelle localization GO:0051656 45 0.018
ectodermal placode morphogenesis GO:0071697 32 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
negative regulation of rna biosynthetic process GO:1902679 45 0.018
thymus development GO:0048538 10 0.018
multi organism reproductive process GO:0044703 36 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
regulation of signal transduction GO:0009966 225 0.018
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.017
forebrain regionalization GO:0021871 4 0.017
nephron tubule epithelial cell differentiation GO:0072160 1 0.017
exocrine pancreas development GO:0031017 28 0.017
negative regulation of cell death GO:0060548 60 0.017
hindbrain development GO:0030902 91 0.017
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.017
negative regulation of stem cell differentiation GO:2000737 2 0.017
cellular localization GO:0051641 97 0.016
single organism reproductive process GO:0044702 40 0.016
regulation of molecular function GO:0065009 70 0.016
dorsal aorta development GO:0035907 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
negative regulation of developmental process GO:0051093 65 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
regulation of programmed cell death GO:0043067 101 0.016
negative regulation of cardiac muscle cell differentiation GO:2000726 1 0.015
cellular component biogenesis GO:0044085 178 0.015
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
neural retina development GO:0003407 49 0.015
amine metabolic process GO:0009308 2 0.015
positive regulation of reproductive process GO:2000243 2 0.015
kupffer s vesicle development GO:0070121 50 0.015
response to chemical GO:0042221 320 0.015
translation GO:0006412 5 0.014
type b pancreatic cell development GO:0003323 4 0.014
cardiac ventricle formation GO:0003211 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of mitosis GO:0045839 3 0.014
neuron differentiation GO:0030182 353 0.014
cell motility GO:0048870 244 0.014
mitotic cell cycle GO:0000278 64 0.014
diencephalon development GO:0021536 58 0.014
renal system vasculature development GO:0061437 2 0.014
hormone secretion GO:0046879 2 0.014
ectoderm formation GO:0001705 2 0.014
hindbrain morphogenesis GO:0021575 22 0.013
regulation of protein complex assembly GO:0043254 3 0.013
mesenchymal cell development GO:0014031 78 0.013
single organism nuclear import GO:1902593 3 0.013
nephron epithelium morphogenesis GO:0072088 1 0.013
regulation of translational initiation GO:0006446 1 0.013
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.013
multicellular organism reproduction GO:0032504 35 0.013
nephron morphogenesis GO:0072028 2 0.013
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
single organism cellular localization GO:1902580 46 0.013
porphyrin containing compound metabolic process GO:0006778 10 0.013
porphyrin containing compound biosynthetic process GO:0006779 8 0.013
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of locomotion GO:0040012 55 0.012
regulation of calcium ion transport GO:0051924 2 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
gas transport GO:0015669 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
pronephric nephron tubule development GO:0039020 2 0.012
pectoral fin development GO:0033339 50 0.012
regulation of cellular component organization GO:0051128 86 0.012
cell proliferation GO:0008283 80 0.012
monocyte differentiation GO:0030224 2 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
kidney vasculature development GO:0061440 2 0.012
regulation of response to external stimulus GO:0032101 31 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
apoptotic process GO:0006915 116 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
response to uv GO:0009411 3 0.012
locomotory behavior GO:0007626 34 0.012
muscle tissue development GO:0060537 110 0.012
protein acylation GO:0043543 3 0.012
ectodermal cell fate specification GO:0001715 2 0.012
cardiac chamber morphogenesis GO:0003206 12 0.011
forebrain neuron differentiation GO:0021879 14 0.011
notochord development GO:0030903 54 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
compound eye development GO:0048749 2 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
regulation of guanylate cyclase activity GO:0031282 6 0.011
cellular amine metabolic process GO:0044106 2 0.011
otolith morphogenesis GO:0032474 8 0.011
transport GO:0006810 220 0.011
protein import GO:0017038 3 0.011
regulation of cardiac chamber morphogenesis GO:1901219 2 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
peptidyl amino acid modification GO:0018193 16 0.011
glomerular visceral epithelial cell fate commitment GO:0072149 4 0.011
epidermal cell differentiation GO:0009913 36 0.011
negative chemotaxis GO:0050919 1 0.011
cellular component movement GO:0006928 335 0.011
ectodermal placode formation GO:0060788 26 0.010
skin development GO:0043588 54 0.010
renal system development GO:0072001 94 0.010
death GO:0016265 121 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
cellular ketone metabolic process GO:0042180 11 0.010
determination of left right asymmetry in diencephalon GO:0035462 4 0.010
inner ear receptor cell differentiation GO:0060113 29 0.010
lipid storage GO:0019915 1 0.010
regulation of kinase activity GO:0043549 15 0.010
nuclear import GO:0051170 3 0.010
response to monosaccharide GO:0034284 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
g2 m transition of mitotic cell cycle GO:0000086 4 0.010
determination of digestive tract left right asymmetry GO:0071907 10 0.010
response to glucose GO:0009749 3 0.010

znfl2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.131
disease of cellular proliferation DOID:14566 0 0.131
organ system cancer DOID:0050686 0 0.131
disease of metabolism DOID:0014667 0 0.033
urinary system cancer DOID:3996 0 0.023
disease of anatomical entity DOID:7 0 0.015