Danio rerio

0 known processes

mpdu1a

mannose-P-dolichol utilization defect 1a

(Aliases: zgc:92112,mpdu1)

mpdu1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.115
cellular nitrogen compound metabolic process GO:0034641 290 0.110
maintenance of location GO:0051235 4 0.100
small molecule metabolic process GO:0044281 77 0.095
striated muscle cell differentiation GO:0051146 129 0.091
larval development GO:0002164 2 0.077
carboxylic acid metabolic process GO:0019752 22 0.072
single organism metabolic process GO:0044710 217 0.070
regulation of synapse organization GO:0050807 3 0.070
organonitrogen compound metabolic process GO:1901564 74 0.070
oxoacid metabolic process GO:0043436 31 0.065
cognition GO:0050890 1 0.064
carboxylic acid catabolic process GO:0046395 3 0.061
organic acid metabolic process GO:0006082 31 0.061
muscle cell development GO:0055001 115 0.059
immune system process GO:0002376 241 0.059
aging GO:0007568 2 0.059
cellular component biogenesis GO:0044085 178 0.059
organic cyclic compound metabolic process GO:1901360 301 0.055
stem cell proliferation GO:0072089 4 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
regulation of biological quality GO:0065008 263 0.050
response to chemical GO:0042221 320 0.049
heart development GO:0007507 313 0.049
cellular component assembly GO:0022607 170 0.048
organic acid catabolic process GO:0016054 3 0.046
system process GO:0003008 185 0.045
alpha amino acid metabolic process GO:1901605 3 0.045
gtp metabolic process GO:0046039 4 0.044
small molecule catabolic process GO:0044282 3 0.044
synaptic growth at neuromuscular junction GO:0051124 2 0.043
positive regulation of cellular catabolic process GO:0031331 3 0.042
neuron development GO:0048666 262 0.041
amine metabolic process GO:0009308 2 0.040
guanosine containing compound metabolic process GO:1901068 4 0.039
positive regulation of catabolic process GO:0009896 4 0.039
regulation of multicellular organism growth GO:0040014 4 0.039
phagocytosis GO:0006909 3 0.039
cellular response to extracellular stimulus GO:0031668 2 0.038
membrane fusion GO:0061025 2 0.037
phosphorus metabolic process GO:0006793 109 0.036
regulation of metabolic process GO:0019222 359 0.036
multicellular organism growth GO:0035264 4 0.035
regulation of cell shape GO:0008360 1 0.035
regulation of response to stimulus GO:0048583 269 0.035
cell surface receptor signaling pathway GO:0007166 325 0.034
nucleobase containing compound metabolic process GO:0006139 274 0.034
lipid storage GO:0019915 1 0.034
response to hexose GO:0009746 3 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
lipid metabolic process GO:0006629 52 0.032
cellular lipid metabolic process GO:0044255 36 0.032
central nervous system development GO:0007417 387 0.032
response to stress GO:0006950 263 0.032
lipid catabolic process GO:0016042 4 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
cellular response to external stimulus GO:0071496 2 0.031
neuron differentiation GO:0030182 353 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.031
regulation of cell communication GO:0010646 232 0.030
neurological system process GO:0050877 62 0.030
regulation of synapse assembly GO:0051963 3 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
heterocycle metabolic process GO:0046483 290 0.030
regulation of dendrite development GO:0050773 3 0.030
protein polymerization GO:0051258 4 0.029
actin polymerization or depolymerization GO:0008154 2 0.029
neuroblast proliferation GO:0007405 2 0.029
determination of bilateral symmetry GO:0009855 204 0.028
cellular amine metabolic process GO:0044106 2 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
cellular ketone metabolic process GO:0042180 11 0.027
positive regulation of secretion by cell GO:1903532 1 0.027
protein metabolic process GO:0019538 183 0.027
cellular lipid catabolic process GO:0044242 3 0.027
cell morphogenesis GO:0000902 289 0.027
positive regulation of cytoskeleton organization GO:0051495 3 0.027
negative regulation of synapse assembly GO:0051964 2 0.027
cellular modified amino acid metabolic process GO:0006575 3 0.027
cellular macromolecule metabolic process GO:0044260 391 0.027
endosomal transport GO:0016197 2 0.026
single organism transport GO:0044765 206 0.026
negative regulation of biological process GO:0048519 304 0.026
organelle organization GO:0006996 227 0.026
regulation of signaling GO:0023051 235 0.026
regulation of gtp catabolic process GO:0033124 2 0.025
positive regulation of transport GO:0051050 2 0.025
gtp catabolic process GO:0006184 2 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
autophagy GO:0006914 4 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
branched chain amino acid metabolic process GO:0009081 1 0.024
muscle cell differentiation GO:0042692 139 0.024
regulation of primary metabolic process GO:0080090 311 0.024
vasculature development GO:0001944 278 0.024
cell projection organization GO:0030030 284 0.023
multi organism process GO:0051704 134 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
single organism localization GO:1902578 225 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
single organism organelle organization GO:1902589 199 0.023
response to glucose GO:0009749 3 0.023
regulation of reproductive process GO:2000241 4 0.023
inositol lipid mediated signaling GO:0048017 2 0.023
cellular response to starvation GO:0009267 1 0.022
regulation of cell projection assembly GO:0060491 4 0.022
specification of symmetry GO:0009799 204 0.022
camera type eye development GO:0043010 222 0.022
regulation of nervous system development GO:0051960 90 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
adult behavior GO:0030534 2 0.022
positive regulation of cell cycle GO:0045787 3 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
cellular response to nutrient levels GO:0031669 2 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.022
phenol containing compound biosynthetic process GO:0046189 4 0.022
leukocyte proliferation GO:0070661 1 0.021
phagocytosis engulfment GO:0006911 1 0.021
rna localization GO:0006403 4 0.021
response to endogenous stimulus GO:0009719 83 0.021
regulation of signal transduction GO:0009966 225 0.021
response to organic substance GO:0010033 153 0.021
neurotransmitter transport GO:0006836 2 0.021
organelle assembly GO:0070925 110 0.021
positive regulation of gtpase activity GO:0043547 1 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
regulation of developmental process GO:0050793 247 0.020
locomotion GO:0040011 313 0.020
ear development GO:0043583 127 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
transport GO:0006810 220 0.020
response to other organism GO:0051707 97 0.020
response to carbohydrate GO:0009743 3 0.019
regulation of filopodium assembly GO:0051489 2 0.019
regulation of blood vessel size GO:0050880 2 0.019
striated muscle cell development GO:0055002 108 0.019
cellular component disassembly GO:0022411 1 0.019
regulation of gtpase activity GO:0043087 2 0.019
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
regulation of cell development GO:0060284 100 0.019
protein heterooligomerization GO:0051291 1 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
establishment of localization GO:0051234 244 0.019
positive regulation of secretion GO:0051047 1 0.019
cell substrate adhesion GO:0031589 4 0.019
actin cytoskeleton organization GO:0030036 63 0.019
protein localization to plasma membrane GO:0072659 1 0.018
growth GO:0040007 174 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of cell differentiation GO:0045595 142 0.018
fatty acid catabolic process GO:0009062 1 0.018
actin filament based process GO:0030029 64 0.018
long chain fatty acid metabolic process GO:0001676 1 0.018
dna templated transcription initiation GO:0006352 1 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
stem cell maintenance GO:0019827 4 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
chordate embryonic development GO:0043009 271 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
cell projection assembly GO:0030031 64 0.017
cortical actin cytoskeleton organization GO:0030866 1 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cytoskeleton organization GO:0007010 96 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
mesenchyme development GO:0060485 127 0.017
forebrain development GO:0030900 96 0.017
response to monosaccharide GO:0034284 3 0.017
outflow tract morphogenesis GO:0003151 1 0.017
skeletal system development GO:0001501 181 0.017
regulation of protein polymerization GO:0032271 2 0.017
actin filament polymerization GO:0030041 2 0.017
fatty acid transport GO:0015908 1 0.017
cellular component morphogenesis GO:0032989 336 0.017
response to external biotic stimulus GO:0043207 97 0.017
positive regulation of biological process GO:0048518 253 0.017
neuron projection development GO:0031175 180 0.017
embryonic organ development GO:0048568 381 0.017
response to external stimulus GO:0009605 264 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
response to alkaloid GO:0043279 2 0.017
heart morphogenesis GO:0003007 156 0.017
regulation of neurogenesis GO:0050767 87 0.017
lateral inhibition GO:0046331 1 0.016
golgi vesicle transport GO:0048193 3 0.016
behavior GO:0007610 74 0.016
regulation of circadian rhythm GO:0042752 4 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
meiotic nuclear division GO:0007126 4 0.016
regulation of autophagy GO:0010506 3 0.016
cellular response to organic substance GO:0071310 105 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
single organism membrane fusion GO:0044801 2 0.016
localization of cell GO:0051674 244 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
cell projection morphogenesis GO:0048858 244 0.016
macroautophagy GO:0016236 1 0.016
stem cell division GO:0017145 1 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
regulation of establishment of protein localization GO:0070201 4 0.015
cell matrix adhesion GO:0007160 4 0.015
digestive system development GO:0055123 289 0.015
eye development GO:0001654 277 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
mononuclear cell proliferation GO:0032943 1 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
angiogenesis GO:0001525 158 0.015
intracellular signal transduction GO:0035556 85 0.015
cortical cytoskeleton organization GO:0030865 1 0.015
long chain fatty acid transport GO:0015909 1 0.015
glucose homeostasis GO:0042593 1 0.015
dopamine metabolic process GO:0042417 2 0.015
gene expression GO:0010467 252 0.015
carbohydrate homeostasis GO:0033500 1 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
blood vessel development GO:0001568 246 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
intracellular mrna localization GO:0008298 1 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
adherens junction organization GO:0034332 4 0.015
liver development GO:0001889 96 0.015
cell part morphogenesis GO:0032990 246 0.015
anterior posterior pattern specification GO:0009952 152 0.015
transcription dna templated GO:0006351 181 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
lymphocyte proliferation GO:0046651 1 0.014
hormone transport GO:0009914 2 0.014
female sex differentiation GO:0046660 4 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
signal transduction GO:0007165 455 0.014
membrane invagination GO:0010324 1 0.014
cell proliferation GO:0008283 80 0.014
blood vessel morphogenesis GO:0048514 216 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
determination of left right symmetry GO:0007368 179 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
cartilage development GO:0051216 96 0.014
digestive tract morphogenesis GO:0048546 231 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
medulla oblongata development GO:0021550 4 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
digestive tract development GO:0048565 265 0.014
somatic muscle development GO:0007525 4 0.014
response to corticosteroid GO:0031960 1 0.013
regulation of endothelial cell proliferation GO:0001936 1 0.013
hormone secretion GO:0046879 2 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
head development GO:0060322 303 0.013
actin filament based movement GO:0030048 1 0.013
secondary metabolic process GO:0019748 3 0.013
regulation of metal ion transport GO:0010959 4 0.013
nuclear transport GO:0051169 4 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
meiotic cell cycle process GO:1903046 3 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
negative regulation of defense response GO:0031348 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
alcohol biosynthetic process GO:0046165 2 0.013
peptide transport GO:0015833 1 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
energy reserve metabolic process GO:0006112 2 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
negative regulation of cellular process GO:0048523 283 0.013
ion transmembrane transport GO:0034220 91 0.013
defense response GO:0006952 47 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
tissue regeneration GO:0042246 74 0.013
regulation of binding GO:0051098 3 0.013
wound healing GO:0042060 90 0.013
muscle structure development GO:0061061 196 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of catalytic activity GO:0050790 55 0.013
central nervous system neuron differentiation GO:0021953 74 0.012
cell cell signaling GO:0007267 52 0.012
regulation of gene expression GO:0010468 265 0.012
response to drug GO:0042493 3 0.012
muscle cell migration GO:0014812 4 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of cell activation GO:0050865 1 0.012
negative chemotaxis GO:0050919 1 0.012
response to wounding GO:0009611 116 0.012
insulin like growth factor receptor signaling pathway GO:0048009 4 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
microtubule based process GO:0007017 60 0.012
positive regulation of endothelial cell proliferation GO:0001938 1 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
neurotransmitter secretion GO:0007269 2 0.012
catabolic process GO:0009056 32 0.012
activation of mapk activity GO:0000187 3 0.012
synaptic vesicle transport GO:0048489 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
protein complex disassembly GO:0043241 1 0.012
centrosome organization GO:0051297 1 0.012
regulation of tube size GO:0035150 2 0.012
biosynthetic process GO:0009058 294 0.012
macromolecular complex disassembly GO:0032984 1 0.012
glial cell migration GO:0008347 3 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
organic substance biosynthetic process GO:1901576 289 0.012
positive regulation of cell activation GO:0050867 1 0.012
fatty acid beta oxidation GO:0006635 1 0.012
regulation of mrna processing GO:0050684 3 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of hormone secretion GO:0046883 2 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
sensory organ development GO:0007423 393 0.011
nucleic acid metabolic process GO:0090304 244 0.011
protein homooligomerization GO:0051260 3 0.011
sensory perception of pain GO:0019233 1 0.011
nucleic acid transport GO:0050657 2 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
lipid homeostasis GO:0055088 3 0.011
nuclear migration GO:0007097 3 0.011
defense response to other organism GO:0098542 33 0.011
cellular protein metabolic process GO:0044267 129 0.011
skeletal system morphogenesis GO:0048705 102 0.011
pyrimidine containing compound metabolic process GO:0072527 3 0.011
regulation of dna replication GO:0006275 3 0.011
rna metabolic process GO:0016070 219 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
nucleobase containing compound transport GO:0015931 2 0.011
protein modification process GO:0036211 100 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
glycerophospholipid biosynthetic process GO:0046474 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
convergent extension GO:0060026 118 0.011
organic substance transport GO:0071702 58 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
cellular biosynthetic process GO:0044249 286 0.011
multi organism reproductive process GO:0044703 36 0.011
response to abiotic stimulus GO:0009628 122 0.011
peptidyl threonine modification GO:0018210 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
organelle fusion GO:0048284 3 0.011
pancreas development GO:0031016 84 0.011
multi organism cellular process GO:0044764 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
immune system development GO:0002520 191 0.010
macromolecule modification GO:0043412 111 0.010
regionalization GO:0003002 274 0.010
response to glucocorticoid GO:0051384 1 0.010
synaptic vesicle localization GO:0097479 1 0.010
response to food GO:0032094 1 0.010
post embryonic organ development GO:0048569 4 0.010
neuronal action potential GO:0019228 18 0.010
regulation of biomineral tissue development GO:0070167 2 0.010
protein targeting to membrane GO:0006612 1 0.010
response to hormone GO:0009725 48 0.010
positive regulation of jak stat cascade GO:0046427 2 0.010
establishment of blood brain barrier GO:0060856 2 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010
glycerolipid biosynthetic process GO:0045017 1 0.010
muscle tissue development GO:0060537 110 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
renal system development GO:0072001 94 0.010
taurine metabolic process GO:0019530 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
cellular biogenic amine metabolic process GO:0006576 2 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
hepaticobiliary system development GO:0061008 98 0.010
oxidation reduction process GO:0055114 41 0.010

mpdu1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.010