Danio rerio

0 known processes

eif5a2

eukaryotic translation initiation factor 5A2

(Aliases: zgc:55504,zgc:77429,wu:fc23f04,wu:fb05b06,wu:fc61c10,EIF5A)

eif5a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance biosynthetic process GO:1901576 289 0.800
Yeast
cellular macromolecule metabolic process GO:0044260 391 0.742
Yeast
regulation of cellular metabolic process GO:0031323 320 0.649
Yeast
biosynthetic process GO:0009058 294 0.634
Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.624
Yeast
macromolecule biosynthetic process GO:0009059 227 0.603
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.595
Yeast
cellular biosynthetic process GO:0044249 286 0.447
Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.422
Yeast
larval development GO:0002164 2 0.419
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.401
Yeast
regulation of primary metabolic process GO:0080090 311 0.394
Yeast
regulation of nucleic acid templated transcription GO:1903506 213 0.367
cellular component biogenesis GO:0044085 178 0.353
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.352
cellular macromolecule biosynthetic process GO:0034645 224 0.349
Yeast
nucleic acid metabolic process GO:0090304 244 0.344
regulation of rna metabolic process GO:0051252 224 0.310
heterocycle metabolic process GO:0046483 290 0.309
rna metabolic process GO:0016070 219 0.294
nitrogen compound metabolic process GO:0006807 319 0.284
transcription dna templated GO:0006351 181 0.267
gene expression GO:0010467 252 0.256
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.255
positive regulation of biological process GO:0048518 253 0.253
Yeast
regulation of macromolecule biosynthetic process GO:0010556 225 0.249
Yeast
cellular nitrogen compound biosynthetic process GO:0044271 218 0.248
regulation of gene expression GO:0010468 265 0.239
Yeast
positive regulation of biosynthetic process GO:0009891 68 0.236
Yeast
nucleobase containing compound metabolic process GO:0006139 274 0.233
regulation of binding GO:0051098 3 0.219
positive regulation of protein complex assembly GO:0031334 2 0.204
negative regulation of cellular process GO:0048523 283 0.201
organic cyclic compound metabolic process GO:1901360 301 0.195
cellular protein metabolic process GO:0044267 129 0.193
Yeast
single fertilization GO:0007338 3 0.191
regulation of biosynthetic process GO:0009889 250 0.183
Yeast
regulation of transcription dna templated GO:0006355 213 0.183
cell surface receptor signaling pathway GO:0007166 325 0.182
fertilization GO:0009566 3 0.177
macromolecular complex subunit organization GO:0043933 74 0.167
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.166
regulation of metabolic process GO:0019222 359 0.165
Yeast
regulation of developmental process GO:0050793 247 0.160
regulation of biological quality GO:0065008 263 0.158
positive regulation of cellular process GO:0048522 201 0.157
Yeast
locomotion GO:0040011 313 0.153
Worm
cellular component assembly GO:0022607 170 0.145
aromatic compound biosynthetic process GO:0019438 217 0.145
microtubule organizing center organization GO:0031023 1 0.143
cellular aromatic compound metabolic process GO:0006725 295 0.142
signal transduction GO:0007165 455 0.142
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.140
cellular nitrogen compound metabolic process GO:0034641 290 0.133
positive regulation of cellular biosynthetic process GO:0031328 68 0.130
Yeast
positive regulation of translation GO:0045727 1 0.127
Yeast
cellular protein catabolic process GO:0044257 4 0.127
modification dependent protein catabolic process GO:0019941 3 0.126
cell death GO:0008219 121 0.121
Worm
positive regulation of macromolecule metabolic process GO:0010604 93 0.119
Yeast
regulation of protein complex assembly GO:0043254 3 0.114
organelle organization GO:0006996 227 0.105
heterocycle biosynthetic process GO:0018130 215 0.104
negative regulation of biological process GO:0048519 304 0.102
multicellular organism growth GO:0035264 4 0.100
rna biosynthetic process GO:0032774 181 0.098
microtubule based process GO:0007017 60 0.097
transport GO:0006810 220 0.092
Worm
translational initiation GO:0006413 3 0.092
Yeast
apoptotic process GO:0006915 116 0.089
Worm
cytokinesis GO:0000910 3 0.089
modification dependent macromolecule catabolic process GO:0043632 3 0.087
meiotic cell cycle process GO:1903046 3 0.086
regulation of rna biosynthetic process GO:2001141 213 0.086
embryo development ending in birth or egg hatching GO:0009792 271 0.085
Worm
regulation of multicellular organismal development GO:2000026 223 0.082
nuclear export GO:0051168 1 0.082
positive regulation of metabolic process GO:0009893 108 0.079
Yeast
dorsal ventral pattern formation GO:0009953 125 0.079
positive regulation of rna biosynthetic process GO:1902680 57 0.079
ubiquitin dependent protein catabolic process GO:0006511 3 0.078
regulation of multicellular organism growth GO:0040014 4 0.078
death GO:0016265 121 0.076
Worm
macromolecular complex assembly GO:0065003 35 0.075
centrosome cycle GO:0007098 1 0.074
regulation of multicellular organismal process GO:0051239 277 0.074
protein polymerization GO:0051258 4 0.073
maturation of ssu rrna GO:0030490 1 0.073
centrosome organization GO:0051297 1 0.073
regulation of cellular component organization GO:0051128 86 0.072
Yeast
response to stress GO:0006950 263 0.072
organelle assembly GO:0070925 110 0.071
single organism organelle organization GO:1902589 199 0.069
nucleoside monophosphate catabolic process GO:0009125 4 0.069
organic cyclic compound biosynthetic process GO:1901362 223 0.068
protein metabolic process GO:0019538 183 0.068
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.067
Yeast
blood vessel morphogenesis GO:0048514 216 0.067
protein modification process GO:0036211 100 0.065
negative regulation of metabolic process GO:0009892 86 0.065
cellular component disassembly GO:0022411 1 0.064
Yeast
positive regulation of transcription dna templated GO:0045893 57 0.064
proteasomal protein catabolic process GO:0010498 2 0.063
establishment of protein localization to organelle GO:0072594 4 0.063
cellular component movement GO:0006928 335 0.063
negative regulation of cellular metabolic process GO:0031324 77 0.062
macromolecular complex disassembly GO:0032984 1 0.062
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.062
nucleic acid templated transcription GO:0097659 181 0.062
cellular protein modification process GO:0006464 100 0.062
cell projection organization GO:0030030 284 0.061
ribonucleoprotein complex biogenesis GO:0022613 13 0.060
response to external biotic stimulus GO:0043207 97 0.060
protein complex disassembly GO:0043241 1 0.060
Yeast
regulation of cellular protein metabolic process GO:0032268 52 0.059
Yeast
positive regulation of gene expression GO:0010628 71 0.059
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.058
protein import GO:0017038 3 0.056
nucleobase containing compound biosynthetic process GO:0034654 205 0.055
regulation of protein localization to nucleus GO:1900180 2 0.054
protein targeting to nucleus GO:0044744 3 0.054
cellular protein complex assembly GO:0043623 19 0.054
multi organism process GO:0051704 134 0.054
Worm
digestive tract development GO:0048565 265 0.054
protein localization to nucleus GO:0034504 3 0.053
response to chemical GO:0042221 320 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.052
macromolecule modification GO:0043412 111 0.052
nuclear import GO:0051170 3 0.051
cytoskeleton organization GO:0007010 96 0.051
aging GO:0007568 2 0.049
Worm
negative regulation of cellular biosynthetic process GO:0031327 55 0.048
meiotic chromosome segregation GO:0045132 3 0.048
positive regulation of cellular catabolic process GO:0031331 3 0.046
neuron differentiation GO:0030182 353 0.046
regulation of cell death GO:0010941 103 0.045
protein import into nucleus GO:0006606 3 0.045
single organism localization GO:1902578 225 0.044
single organism metabolic process GO:0044710 217 0.043
regulation of cell communication GO:0010646 232 0.042
rrna metabolic process GO:0016072 8 0.042
single organism nuclear import GO:1902593 3 0.042
nuclear migration GO:0007097 3 0.042
regulation of protein catabolic process GO:0042176 1 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
meiotic nuclear division GO:0007126 4 0.041
tube morphogenesis GO:0035239 349 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.040
cellular component assembly involved in morphogenesis GO:0010927 107 0.040
protein complex subunit organization GO:0071822 46 0.040
Yeast
regulation of establishment of protein localization GO:0070201 4 0.040
positive regulation of cellular component biogenesis GO:0044089 3 0.039
maintenance of location GO:0051235 4 0.039
homeostatic process GO:0042592 142 0.038
response to organic substance GO:0010033 153 0.038
cellular macromolecular complex assembly GO:0034622 24 0.038
regulation of translational initiation GO:0006446 1 0.037
Yeast
regulation of proteolysis GO:0030162 24 0.036
establishment of localization GO:0051234 244 0.036
Worm
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.034
rna processing GO:0006396 25 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.033
cell cycle GO:0007049 93 0.033
growth GO:0040007 174 0.032
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.032
amine metabolic process GO:0009308 2 0.031
negative regulation of macromolecule metabolic process GO:0010605 76 0.031
localization of cell GO:0051674 244 0.030
negative regulation of cell communication GO:0010648 96 0.030
chemotaxis GO:0006935 104 0.030
positive regulation of transport GO:0051050 2 0.029
muscle structure development GO:0061061 196 0.029
cell projection morphogenesis GO:0048858 244 0.029
cellular response to stress GO:0033554 62 0.029
transcription from rna polymerase ii promoter GO:0006366 80 0.029
regulation of localization GO:0032879 104 0.029
positive regulation of catabolic process GO:0009896 4 0.029
positive regulation of molecular function GO:0044093 33 0.028
cellular component morphogenesis GO:0032989 336 0.028
regulation of signaling GO:0023051 235 0.028
protein n linked glycosylation GO:0006487 1 0.028
positive regulation of rna metabolic process GO:0051254 59 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.028
mitotic cell cycle GO:0000278 64 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.028
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.028
regulation of protein transport GO:0051223 3 0.028
cellular macromolecule localization GO:0070727 21 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
organelle localization GO:0051640 49 0.027
regulation of response to stimulus GO:0048583 269 0.027
protein complex biogenesis GO:0070271 30 0.027
regulation of cell shape GO:0008360 1 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.027
cell morphogenesis GO:0000902 289 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
regulation of cell cycle GO:0051726 52 0.026
negative regulation of signaling GO:0023057 96 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
proteolysis GO:0006508 38 0.026
nuclear transport GO:0051169 4 0.026
ribosome biogenesis GO:0042254 9 0.025
cellular amine metabolic process GO:0044106 2 0.025
regulation of cell differentiation GO:0045595 142 0.025
positive regulation of protein metabolic process GO:0051247 23 0.025
Yeast
vasculature development GO:0001944 278 0.025
programmed cell death GO:0012501 119 0.025
Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
generation of neurons GO:0048699 385 0.025
blood vessel development GO:0001568 246 0.024
regulation of protein targeting GO:1903533 2 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
intracellular transport GO:0046907 32 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
spermatid development GO:0007286 2 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
protein complex assembly GO:0006461 30 0.023
negative regulation of gene expression GO:0010629 65 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
negative regulation of programmed cell death GO:0043069 58 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
regulation of protein metabolic process GO:0051246 56 0.022
Yeast
regulation of cellular protein catabolic process GO:1903362 1 0.022
mrna metabolic process GO:0016071 20 0.022
posttranscriptional regulation of gene expression GO:0010608 14 0.022
Yeast
embryonic organ development GO:0048568 381 0.022
regulation of mrna splicing via spliceosome GO:0048024 3 0.022
cell motility GO:0048870 244 0.022
cellular protein complex disassembly GO:0043624 1 0.021
Yeast
cellular response to dna damage stimulus GO:0006974 24 0.021
negative regulation of cell death GO:0060548 60 0.021
gamete generation GO:0007276 33 0.021
Worm
positive regulation of cell cycle GO:0045787 3 0.021
pole plasm assembly GO:0007315 4 0.020
dna templated transcription elongation GO:0006354 3 0.020
cell part morphogenesis GO:0032990 246 0.020
gastrulation GO:0007369 208 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
regionalization GO:0003002 274 0.020
translation GO:0006412 5 0.019
Yeast
cell migration GO:0016477 237 0.019
atp catabolic process GO:0006200 4 0.019
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.019
microtubule polymerization or depolymerization GO:0031109 3 0.019
negative regulation of rna metabolic process GO:0051253 48 0.019
response to lipid GO:0033993 60 0.019
regulation of response to stress GO:0080134 36 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.019
microtubule cytoskeleton organization GO:0000226 33 0.019
sensory organ development GO:0007423 393 0.019
reproduction GO:0000003 40 0.019
Worm
response to biotic stimulus GO:0009607 97 0.018
regulation of synapse assembly GO:0051963 3 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cell cell recognition GO:0009988 1 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.018
regulation of reproductive process GO:2000241 4 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
negative regulation of signal transduction GO:0009968 94 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
taxis GO:0042330 109 0.018
angiogenesis GO:0001525 158 0.018
response to virus GO:0009615 21 0.018
negative regulation of translation GO:0017148 1 0.018
neuron development GO:0048666 262 0.017
positive regulation of proteolysis GO:0045862 10 0.017
regulation of protein complex disassembly GO:0043244 1 0.017
Yeast
rna catabolic process GO:0006401 7 0.017
regulation of growth GO:0040008 42 0.017
pronuclear migration GO:0035046 1 0.017
response to other organism GO:0051707 97 0.017
response to external stimulus GO:0009605 264 0.017
regulation of programmed cell death GO:0043067 101 0.017
regulation of molecular function GO:0065009 70 0.017
regulation of mrna processing GO:0050684 3 0.017
protein localization GO:0008104 40 0.017
Worm
nucleic acid transport GO:0050657 2 0.017
intracellular signal transduction GO:0035556 85 0.017
developmental growth GO:0048589 166 0.017
actin filament polymerization GO:0030041 2 0.016
regulation of apoptotic process GO:0042981 98 0.016
establishment of localization in cell GO:0051649 77 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.016
regulation of protein binding GO:0043393 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
negative regulation of biosynthetic process GO:0009890 55 0.015
positive regulation of cellular protein metabolic process GO:0032270 22 0.015
Yeast
digestive system development GO:0055123 289 0.015
regulation of signal transduction GO:0009966 225 0.015
regulation of transport GO:0051049 45 0.015
wnt signaling pathway GO:0016055 80 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
cellular response to organic substance GO:0071310 105 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
regulation of cytokine production GO:0001817 3 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
regulation of synapse organization GO:0050807 3 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
regulation of developmental growth GO:0048638 38 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
positive regulation of developmental process GO:0051094 50 0.014
oxoacid metabolic process GO:0043436 31 0.014
defense response GO:0006952 47 0.014
digestive tract morphogenesis GO:0048546 231 0.014
regulation of protein polymerization GO:0032271 2 0.014
head development GO:0060322 303 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
microtubule polymerization GO:0046785 2 0.014
organic acid metabolic process GO:0006082 31 0.013
mitotic cell cycle process GO:1903047 48 0.013
neuron projection morphogenesis GO:0048812 161 0.013
response to organic cyclic compound GO:0014070 51 0.013
small molecule metabolic process GO:0044281 77 0.013
reproductive process GO:0022414 40 0.013
Worm
response to drug GO:0042493 3 0.013
adult behavior GO:0030534 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
negative regulation of kinase activity GO:0033673 4 0.013
centrosome duplication GO:0051298 1 0.013
female gonad development GO:0008585 4 0.012
cellular localization GO:0051641 97 0.012
ribonucleoprotein complex subunit organization GO:0071826 8 0.012
nuclear transcribed mrna catabolic process GO:0000956 4 0.012
response to endogenous stimulus GO:0009719 83 0.012
brain development GO:0007420 293 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
regulation of cell development GO:0060284 100 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
cellular response to external stimulus GO:0071496 2 0.012
cell cycle process GO:0022402 53 0.012
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
system process GO:0003008 185 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
cellular ketone metabolic process GO:0042180 11 0.011
rna transport GO:0050658 2 0.011
regulation of catalytic activity GO:0050790 55 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
muscle cell development GO:0055001 115 0.011
negative regulation of protein transport GO:0051224 3 0.011
neuron projection development GO:0031175 180 0.011
protein stabilization GO:0050821 2 0.011
dna catabolic process GO:0006308 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
response to hydrogen peroxide GO:0042542 3 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
meiotic spindle organization GO:0000212 1 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
negative regulation of cell cycle GO:0045786 14 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
regulation of translation GO:0006417 3 0.010
Yeast
autophagy GO:0006914 4 0.010
glycoprotein biosynthetic process GO:0009101 21 0.010

eif5a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.093
nervous system disease DOID:863 0 0.018
neuromuscular disease DOID:440 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuropathy DOID:870 0 0.012
musculoskeletal system disease DOID:17 0 0.012