Danio rerio

29 known processes

elovl2

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2

(Aliases: zgc:136352,MGC158526,MGC136352)

elovl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid catabolic process GO:0016054 3 0.238
carboxylic acid catabolic process GO:0046395 3 0.178
cellular biosynthetic process GO:0044249 286 0.170
cellular response to molecule of bacterial origin GO:0071219 3 0.146
hepaticobiliary system development GO:0061008 98 0.144
small molecule catabolic process GO:0044282 3 0.138
single organism metabolic process GO:0044710 217 0.138
regulation of protein catabolic process GO:0042176 1 0.130
nitrogen compound metabolic process GO:0006807 319 0.122
cellular response to lipopolysaccharide GO:0071222 3 0.115
response to stress GO:0006950 263 0.112
response to chemical GO:0042221 320 0.110
cellular response to biotic stimulus GO:0071216 3 0.108
cellular response to chemical stimulus GO:0070887 157 0.104
response to organic substance GO:0010033 153 0.100
cellular aromatic compound metabolic process GO:0006725 295 0.093
organic substance biosynthetic process GO:1901576 289 0.086
superoxide metabolic process GO:0006801 2 0.085
organic acid metabolic process GO:0006082 31 0.085
regulation of biosynthetic process GO:0009889 250 0.083
biosynthetic process GO:0009058 294 0.083
small molecule metabolic process GO:0044281 77 0.076
reactive nitrogen species metabolic process GO:2001057 0 0.076
circadian rhythm GO:0007623 19 0.076
endosomal transport GO:0016197 2 0.075
reactive oxygen species biosynthetic process GO:1903409 1 0.074
embryonic organ morphogenesis GO:0048562 274 0.073
signal transduction GO:0007165 455 0.071
maintenance of location GO:0051235 4 0.071
protein metabolic process GO:0019538 183 0.065
lipid storage GO:0019915 1 0.065
nucleobase containing compound metabolic process GO:0006139 274 0.064
aging GO:0007568 2 0.064
defense response to bacterium GO:0042742 22 0.061
larval development GO:0002164 2 0.060
organic cyclic compound metabolic process GO:1901360 301 0.060
heterocycle metabolic process GO:0046483 290 0.060
cellular macromolecule metabolic process GO:0044260 391 0.059
multicellular organism growth GO:0035264 4 0.059
cellular response to lipid GO:0071396 39 0.058
nucleocytoplasmic transport GO:0006913 4 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.057
alpha amino acid metabolic process GO:1901605 3 0.056
cellular response to organic substance GO:0071310 105 0.055
liver development GO:0001889 96 0.054
regulation of macromolecule metabolic process GO:0060255 317 0.053
gene expression GO:0010467 252 0.052
response to xenobiotic stimulus GO:0009410 45 0.052
neurotransmitter secretion GO:0007269 2 0.048
cellular macromolecule biosynthetic process GO:0034645 224 0.048
phagocytosis GO:0006909 3 0.048
regulation of metabolic process GO:0019222 359 0.047
axonogenesis GO:0007409 152 0.046
heterocycle biosynthetic process GO:0018130 215 0.046
regulation of response to stimulus GO:0048583 269 0.045
nitric oxide biosynthetic process GO:0006809 2 0.045
neuron neuron synaptic transmission GO:0007270 1 0.044
lipid catabolic process GO:0016042 4 0.044
single organism biosynthetic process GO:0044711 71 0.044
oxoacid metabolic process GO:0043436 31 0.043
carboxylic acid metabolic process GO:0019752 22 0.043
negative regulation of catabolic process GO:0009895 3 0.043
activation of immune response GO:0002253 9 0.042
g protein coupled receptor signaling pathway GO:0007186 74 0.040
nucleic acid metabolic process GO:0090304 244 0.039
regulation of dna replication GO:0006275 3 0.039
response to glucocorticoid GO:0051384 1 0.038
growth GO:0040007 174 0.038
regulation of primary metabolic process GO:0080090 311 0.038
adult behavior GO:0030534 2 0.038
regulation of carbohydrate metabolic process GO:0006109 4 0.038
transmembrane transport GO:0055085 120 0.038
immune system process GO:0002376 241 0.038
positive regulation of transport GO:0051050 2 0.037
transcription dna templated GO:0006351 181 0.037
reactive oxygen species metabolic process GO:0072593 6 0.037
macromolecule biosynthetic process GO:0009059 227 0.036
neuron development GO:0048666 262 0.036
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
response to drug GO:0042493 3 0.035
response to monosaccharide GO:0034284 3 0.034
transport GO:0006810 220 0.034
cellular response to external stimulus GO:0071496 2 0.034
striated muscle cell differentiation GO:0051146 129 0.034
response to hormone GO:0009725 48 0.034
protein import into nucleus GO:0006606 3 0.033
mitochondrion organization GO:0007005 4 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
long chain fatty acid metabolic process GO:0001676 1 0.033
Zebrafish
defense response to other organism GO:0098542 33 0.032
cell projection morphogenesis GO:0048858 244 0.032
response to nutrient GO:0007584 3 0.032
organonitrogen compound metabolic process GO:1901564 74 0.032
developmental cell growth GO:0048588 52 0.031
protein modification process GO:0036211 100 0.031
toll like receptor signaling pathway GO:0002224 4 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
response to biotic stimulus GO:0009607 97 0.031
nuclear transport GO:0051169 4 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
response to external stimulus GO:0009605 264 0.030
negative regulation of biological process GO:0048519 304 0.030
regulation of reactive oxygen species metabolic process GO:2000377 2 0.029
regulation of dendrite development GO:0050773 3 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.029
gland development GO:0048732 143 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
response to other organism GO:0051707 97 0.029
system process GO:0003008 185 0.029
establishment of localization GO:0051234 244 0.028
dorsal ventral pattern formation GO:0009953 125 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
generation of neurons GO:0048699 385 0.028
neuron differentiation GO:0030182 353 0.028
negative regulation of cellular process GO:0048523 283 0.028
very long chain fatty acid biosynthetic process GO:0042761 4 0.028
regulation of gene expression GO:0010468 265 0.028
cellular protein metabolic process GO:0044267 129 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.027
central nervous system development GO:0007417 387 0.027
developmental growth GO:0048589 166 0.027
developmental growth involved in morphogenesis GO:0060560 86 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
response to glucose GO:0009749 3 0.027
negative regulation of protein transport GO:0051224 3 0.026
response to molecule of bacterial origin GO:0002237 14 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
response to alkaloid GO:0043279 2 0.026
inorganic ion transmembrane transport GO:0098660 57 0.026
response to oxygen containing compound GO:1901700 55 0.026
single organism localization GO:1902578 225 0.026
spinal cord development GO:0021510 46 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.025
nitric oxide metabolic process GO:0046209 2 0.025
regulation of metal ion transport GO:0010959 4 0.025
single organism transport GO:0044765 206 0.024
head development GO:0060322 303 0.024
embryonic heart tube development GO:0035050 133 0.024
negative regulation of mapk cascade GO:0043409 4 0.023
rna metabolic process GO:0016070 219 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
heart development GO:0007507 313 0.023
embryonic organ development GO:0048568 381 0.023
tube morphogenesis GO:0035239 349 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
macromolecule modification GO:0043412 111 0.023
response to hexose GO:0009746 3 0.023
regulation of inflammatory response GO:0050727 2 0.022
single organism nuclear import GO:1902593 3 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
protein targeting to nucleus GO:0044744 3 0.022
positive regulation of cell cycle GO:0045787 3 0.022
muscle cell development GO:0055001 115 0.021
cell part morphogenesis GO:0032990 246 0.021
cation transmembrane transport GO:0098655 65 0.021
homeostatic process GO:0042592 142 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
ion transmembrane transport GO:0034220 91 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
cellular respiration GO:0045333 3 0.020
complement activation GO:0006956 3 0.020
nuclear import GO:0051170 3 0.020
response to bacterium GO:0009617 58 0.020
regulation of rna metabolic process GO:0051252 224 0.020
cellular protein catabolic process GO:0044257 4 0.020
rna biosynthetic process GO:0032774 181 0.020
response to carbohydrate GO:0009743 3 0.020
response to vitamin GO:0033273 3 0.020
spermatid development GO:0007286 2 0.020
sensory organ development GO:0007423 393 0.020
retina development in camera type eye GO:0060041 146 0.020
immune response GO:0006955 28 0.020
response to corticosteroid GO:0031960 1 0.019
negative regulation of kinase activity GO:0033673 4 0.019
cellular component morphogenesis GO:0032989 336 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
glucose homeostasis GO:0042593 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
response to lipid GO:0033993 60 0.019
cellular response to interferon gamma GO:0071346 1 0.019
organelle assembly GO:0070925 110 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of cell activation GO:0050865 1 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
amine metabolic process GO:0009308 2 0.019
fatty acid elongation GO:0030497 1 0.019
Human Zebrafish Mouse
regulation of protein metabolic process GO:0051246 56 0.019
cellular amine metabolic process GO:0044106 2 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
stem cell division GO:0017145 1 0.018
meiotic nuclear division GO:0007126 4 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
response to external biotic stimulus GO:0043207 97 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
cell growth GO:0016049 57 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
innate immune response GO:0045087 13 0.018
nucleic acid templated transcription GO:0097659 181 0.018
hemopoiesis GO:0030097 183 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of biological quality GO:0065008 263 0.018
cellular response to nutrient levels GO:0031669 2 0.017
cellular response to endogenous stimulus GO:0071495 68 0.017
inorganic cation transmembrane transport GO:0098662 50 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
alcohol biosynthetic process GO:0046165 2 0.017
response to endogenous stimulus GO:0009719 83 0.017
intracellular signal transduction GO:0035556 85 0.017
response to ketone GO:1901654 1 0.017
electron transport chain GO:0022900 2 0.017
positive regulation of cellular process GO:0048522 201 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
hormone secretion GO:0046879 2 0.017
synaptic vesicle localization GO:0097479 1 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
positive regulation of catabolic process GO:0009896 4 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
regulation of protein targeting GO:1903533 2 0.016
cellular response to cytokine stimulus GO:0071345 7 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
carbohydrate homeostasis GO:0033500 1 0.016
negative regulation of secretion GO:0051048 2 0.016
regulation of immune response GO:0050776 14 0.016
lipid oxidation GO:0034440 1 0.016
regulation of calcium ion transport GO:0051924 2 0.016
regulation of reproductive process GO:2000241 4 0.016
protein complex localization GO:0031503 1 0.015
cellular amide metabolic process GO:0043603 4 0.015
response to hypoxia GO:0001666 25 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
multi organism process GO:0051704 134 0.015
cellular lipid metabolic process GO:0044255 36 0.015
oxidation reduction process GO:0055114 41 0.015
cellular response to xenobiotic stimulus GO:0071466 35 0.015
positive regulation of cell activation GO:0050867 1 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
protein localization to nucleus GO:0034504 3 0.015
compound eye development GO:0048749 2 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
cellular protein modification process GO:0006464 100 0.015
peptide metabolic process GO:0006518 1 0.015
negative regulation of gene expression GO:0010629 65 0.015
regulation of gtpase activity GO:0043087 2 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of protein transport GO:0051223 3 0.015
chordate embryonic development GO:0043009 271 0.015
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.015
Human Zebrafish Mouse
cellular response to extracellular stimulus GO:0031668 2 0.014
respiratory electron transport chain GO:0022904 2 0.014
fatty acid biosynthetic process GO:0006633 4 0.014
cellular ketone metabolic process GO:0042180 11 0.014
cell projection organization GO:0030030 284 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
positive regulation of secretion GO:0051047 1 0.014
eye development GO:0001654 277 0.014
striated muscle cell development GO:0055002 108 0.014
specification of symmetry GO:0009799 204 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
cytokinesis GO:0000910 3 0.014
organic substance catabolic process GO:1901575 28 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
cellular response to steroid hormone stimulus GO:0071383 31 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
negative regulation of defense response GO:0031348 2 0.014
gtp catabolic process GO:0006184 2 0.014
spermatid differentiation GO:0048515 2 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
lipid metabolic process GO:0006629 52 0.013
pyruvate metabolic process GO:0006090 1 0.013
determination of left right symmetry GO:0007368 179 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of tube size GO:0035150 2 0.013
hematopoietic stem cell differentiation GO:0060218 20 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
antimicrobial humoral response GO:0019730 2 0.013
regulation of signaling GO:0023051 235 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
response to uv GO:0009411 3 0.013
very long chain fatty acid metabolic process GO:0000038 4 0.013
negative regulation of metabolic process GO:0009892 86 0.013
cellular response to oxygen levels GO:0071453 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
cellular lipid catabolic process GO:0044242 3 0.013
cellular response to drug GO:0035690 1 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
organelle fusion GO:0048284 3 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
cation transport GO:0006812 81 0.013
female gonad development GO:0008585 4 0.013
secondary metabolic process GO:0019748 3 0.012
camera type eye development GO:0043010 222 0.012
gas transport GO:0015669 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
monocarboxylic acid catabolic process GO:0072329 3 0.012
regulation of binding GO:0051098 3 0.012
regulation of transporter activity GO:0032409 2 0.012
cellular response to starvation GO:0009267 1 0.012
vasculature development GO:0001944 278 0.012
response to oxygen levels GO:0070482 25 0.012
ovulation cycle process GO:0022602 2 0.012
mononuclear cell proliferation GO:0032943 1 0.012
organelle organization GO:0006996 227 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
monocarboxylic acid biosynthetic process GO:0072330 12 0.012
catabolic process GO:0009056 32 0.012
phagocytosis engulfment GO:0006911 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
rna localization GO:0006403 4 0.012
fertilization GO:0009566 3 0.012
inner ear development GO:0048839 126 0.012
response to wounding GO:0009611 116 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of jak stat cascade GO:0046425 3 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
terpenoid metabolic process GO:0006721 15 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
response to decreased oxygen levels GO:0036293 25 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cell migration GO:0016477 237 0.011
xenobiotic metabolic process GO:0006805 4 0.011
autophagy GO:0006914 4 0.011
lipid homeostasis GO:0055088 3 0.011
regulation of developmental process GO:0050793 247 0.011
nitric oxide mediated signal transduction GO:0007263 2 0.011
cell morphogenesis GO:0000902 289 0.011
acylglycerol homeostasis GO:0055090 2 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of transport GO:0051049 45 0.011
renal absorption GO:0070293 1 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
cytoskeleton organization GO:0007010 96 0.011
regulation of blood pressure GO:0008217 1 0.011
response to organic cyclic compound GO:0014070 51 0.011
locomotion GO:0040011 313 0.011
cell cell signaling GO:0007267 52 0.011
digestive system development GO:0055123 289 0.011
cognition GO:0050890 1 0.011
regulation of sodium ion transport GO:0002028 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of cytokine production GO:0001817 3 0.010
positive regulation of metabolic process GO:0009893 108 0.010
neurotransmitter transport GO:0006836 2 0.010
positive regulation of immune effector process GO:0002699 3 0.010
cellular component disassembly GO:0022411 1 0.010
forebrain cell migration GO:0021885 1 0.010
transmission of nerve impulse GO:0019226 19 0.010
heart contraction GO:0060047 71 0.010
carbon dioxide transport GO:0015670 3 0.010
protein homooligomerization GO:0051260 3 0.010
axon development GO:0061564 166 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
positive regulation of cytokine production GO:0001819 2 0.010
regulation of signal transduction GO:0009966 225 0.010
rhythmic process GO:0048511 21 0.010
protein secretion GO:0009306 1 0.010
membrane invagination GO:0010324 1 0.010
lymphocyte proliferation GO:0046651 1 0.010
digestive tract development GO:0048565 265 0.010

elovl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014