Danio rerio

13 known processes

twist1a

twist1a

(Aliases: twist-1,twist1,zgc:101115,wu:fd04c01,Twist1b)

twist1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 0.996
Zebrafish
heart morphogenesis GO:0003007 156 0.995
Zebrafish
embryonic organ development GO:0048568 381 0.990
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.978
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.976
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.976
chordate embryonic development GO:0043009 271 0.976
embryonic skeletal system development GO:0048706 97 0.975
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.971
Zebrafish Worm Fly
heart jogging GO:0003146 40 0.961
regionalization GO:0003002 274 0.936
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.931
optic placode formation involved in camera type eye formation GO:0046619 3 0.926
embryonic skeletal system morphogenesis GO:0048704 93 0.920
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.913
Zebrafish Fly
regulation of response to stimulus GO:0048583 269 0.912
heart development GO:0007507 313 0.907
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.907
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.906
Zebrafish
sensory organ development GO:0007423 393 0.899
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.898
Zebrafish
vasculogenesis GO:0001570 41 0.883
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.871
Zebrafish Worm Fly
blood vessel development GO:0001568 246 0.864
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.861
Zebrafish Worm Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.859
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.853
Zebrafish
neural crest cell differentiation GO:0014033 72 0.796
nucleobase containing compound biosynthetic process GO:0034654 205 0.787
Zebrafish Worm Fly
negative regulation of axon guidance GO:1902668 1 0.774
circulatory system process GO:0003013 87 0.761
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.755
Zebrafish Worm Fly
forebrain development GO:0030900 96 0.751
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.748
Zebrafish Worm Fly
positive regulation of biological process GO:0048518 253 0.743
Zebrafish Worm Fly
signal transduction GO:0007165 455 0.742
embryo development ending in birth or egg hatching GO:0009792 271 0.739
determination of left right symmetry GO:0007368 179 0.722
Zebrafish
neuron differentiation GO:0030182 353 0.715
Zebrafish
establishment of localization in cell GO:0051649 77 0.710
stem cell development GO:0048864 82 0.707
response to abiotic stimulus GO:0009628 122 0.701
embryonic heart tube development GO:0035050 133 0.699
Zebrafish
digestive tract development GO:0048565 265 0.699
Zebrafish Worm Fly
anterior posterior pattern specification GO:0009952 152 0.690
optic placode formation GO:0001743 4 0.688
cartilage development GO:0051216 96 0.680
regulation of biosynthetic process GO:0009889 250 0.677
Zebrafish Worm Fly
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.675
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.669
Worm Fly
cell cycle GO:0007049 93 0.667
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.664
convergent extension involved in gastrulation GO:0060027 71 0.662
blood vessel morphogenesis GO:0048514 216 0.657
Zebrafish
locomotion GO:0040011 313 0.641
regulation of signaling GO:0023051 235 0.641
protein metabolic process GO:0019538 183 0.628
connective tissue development GO:0061448 99 0.628
lateral inhibition GO:0046331 1 0.620
immune system process GO:0002376 241 0.610
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.606
biosynthetic process GO:0009058 294 0.605
Zebrafish Worm Fly
mitotic nuclear division GO:0007067 18 0.595
regulation of cell communication GO:0010646 232 0.577
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.573
embryonic camera type eye formation GO:0060900 10 0.570
dorsal convergence GO:0060030 14 0.570
angiogenesis GO:0001525 158 0.567
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.535
Zebrafish Fly
regulation of multicellular organismal development GO:2000026 223 0.532
Zebrafish Fly
cell migration GO:0016477 237 0.531
cell fate commitment GO:0045165 99 0.530
Zebrafish Worm Fly
regulation of developmental process GO:0050793 247 0.525
Zebrafish Fly
positive regulation of cellular metabolic process GO:0031325 94 0.520
Zebrafish Worm Fly
cell cell signaling involved in cell fate commitment GO:0045168 12 0.512
response to external stimulus GO:0009605 264 0.510
cell part morphogenesis GO:0032990 246 0.509
regulation of chondrocyte differentiation GO:0032330 1 0.502
neural crest cell development GO:0014032 62 0.501
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.500
determination of heart left right asymmetry GO:0061371 117 0.496
organic substance biosynthetic process GO:1901576 289 0.496
Zebrafish Worm Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.489
cellular protein metabolic process GO:0044267 129 0.489
regulation of dna replication GO:0006275 3 0.484
embryonic limb morphogenesis GO:0030326 2 0.482
gland development GO:0048732 143 0.478
Zebrafish Fly
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.476
phosphorylation GO:0016310 69 0.474
neuron development GO:0048666 262 0.472
Zebrafish
specification of symmetry GO:0009799 204 0.471
Zebrafish
regulation of meiotic cell cycle GO:0051445 1 0.467
cellular biosynthetic process GO:0044249 286 0.467
Zebrafish Worm Fly
mesenchymal cell differentiation GO:0048762 87 0.467
nuclear transport GO:0051169 4 0.466
kidney development GO:0001822 92 0.465
head development GO:0060322 303 0.461
Zebrafish
response to chemical GO:0042221 320 0.449
cell motility GO:0048870 244 0.446
retina development in camera type eye GO:0060041 146 0.446
Zebrafish
cellular component movement GO:0006928 335 0.438
mesenchymal cell development GO:0014031 78 0.425
positive regulation of cellular process GO:0048522 201 0.422
Zebrafish Worm Fly
rna biosynthetic process GO:0032774 181 0.421
Zebrafish Worm Fly
negative regulation of chemotaxis GO:0050922 4 0.415
organic cyclic compound metabolic process GO:1901360 301 0.412
Zebrafish Worm Fly
tube morphogenesis GO:0035239 349 0.397
Zebrafish Worm Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.395
Zebrafish Worm Fly
localization of cell GO:0051674 244 0.392
enzyme linked receptor protein signaling pathway GO:0007167 106 0.391
blood circulation GO:0008015 87 0.384
Zebrafish
system process GO:0003008 185 0.383
Zebrafish
vasculature development GO:0001944 278 0.382
Zebrafish
olfactory lobe development GO:0021988 4 0.381
Zebrafish
nephron tubule morphogenesis GO:0072078 1 0.372
ameboidal type cell migration GO:0001667 143 0.368
motor neuron axon guidance GO:0008045 23 0.368
positive regulation of gene expression GO:0010628 71 0.365
Zebrafish Worm Fly
neurological system process GO:0050877 62 0.360
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.348
positive regulation of metabolic process GO:0009893 108 0.345
Zebrafish Worm Fly
regulation of cellular biosynthetic process GO:0031326 245 0.341
Zebrafish Worm Fly
regulation of mesenchymal cell proliferation GO:0010464 1 0.337
regulation of cellular metabolic process GO:0031323 320 0.335
Zebrafish Worm Fly
positive regulation of muscle organ development GO:0048636 1 0.334
renal system development GO:0072001 94 0.326
Fly
cranial nerve development GO:0021545 42 0.326
Zebrafish
somitogenesis GO:0001756 87 0.324
muscle cell differentiation GO:0042692 139 0.323
Fly
heterocycle metabolic process GO:0046483 290 0.317
Zebrafish Worm Fly
camera type eye development GO:0043010 222 0.310
Zebrafish
negative regulation of biological process GO:0048519 304 0.307
Zebrafish Fly
ossification GO:0001503 23 0.307
anterior posterior axon guidance GO:0033564 5 0.306
response to lipid GO:0033993 60 0.302
cellular aromatic compound metabolic process GO:0006725 295 0.301
Zebrafish Worm Fly
negative regulation of cell communication GO:0010648 96 0.298
meiotic nuclear division GO:0007126 4 0.295
protein targeting to nucleus GO:0044744 3 0.291
endocardium development GO:0003157 9 0.284
Zebrafish
regeneration GO:0031099 91 0.283
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.273
forebrain regionalization GO:0021871 4 0.272
protein localization GO:0008104 40 0.269
positive regulation of nucleic acid templated transcription GO:1903508 57 0.264
Zebrafish Worm Fly
reproductive process GO:0022414 40 0.264
Worm
nucleic acid templated transcription GO:0097659 181 0.263
Zebrafish Worm Fly
cellular localization GO:0051641 97 0.263
sprouting angiogenesis GO:0002040 53 0.258
single organism localization GO:1902578 225 0.257
organelle organization GO:0006996 227 0.256
Fly
stem cell maintenance GO:0019827 4 0.251
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.248
cellular response to chemical stimulus GO:0070887 157 0.248
single organism cell adhesion GO:0098602 29 0.248
regulation of signal transduction GO:0009966 225 0.247
positive regulation of multicellular organismal process GO:0051240 52 0.246
Zebrafish
spinal cord anterior posterior patterning GO:0021512 1 0.245
nephron epithelium morphogenesis GO:0072088 1 0.243
carbohydrate derivative metabolic process GO:1901135 61 0.239
negative regulation of wnt signaling pathway GO:0030178 30 0.238
epithelial cell migration GO:0010631 25 0.236
response to stress GO:0006950 263 0.236
Zebrafish
positive regulation of muscle tissue development GO:1901863 1 0.233
digestive system development GO:0055123 289 0.232
Zebrafish Worm Fly
positive regulation of cell communication GO:0010647 56 0.230
histone modification GO:0016570 20 0.230
regulation of anatomical structure morphogenesis GO:0022603 130 0.230
embryonic heart tube morphogenesis GO:0003143 108 0.227
Zebrafish
cell cell signaling GO:0007267 52 0.227
single organism nuclear import GO:1902593 3 0.223
positive regulation of cellular biosynthetic process GO:0031328 68 0.222
Zebrafish Worm Fly
urogenital system development GO:0001655 97 0.219
Fly
gene expression GO:0010467 252 0.219
Zebrafish Worm Fly
regulation of biological quality GO:0065008 263 0.219
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.218
Zebrafish Worm Fly
negative regulation of signaling GO:0023057 96 0.217
respiratory system development GO:0060541 5 0.214
regulation of smoothened signaling pathway GO:0008589 18 0.214
stem cell differentiation GO:0048863 117 0.208
Zebrafish
regulation of cardiac muscle tissue development GO:0055024 1 0.208
tube closure GO:0060606 1 0.206
brain development GO:0007420 293 0.205
Zebrafish
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.204
regulation of locomotion GO:0040012 55 0.203
endoderm development GO:0007492 49 0.203
hepatocyte proliferation GO:0072574 2 0.203
positive regulation of smoothened signaling pathway GO:0045880 5 0.203
diencephalon development GO:0021536 58 0.197
phosphorus metabolic process GO:0006793 109 0.196
wound healing GO:0042060 90 0.193
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.193
Zebrafish Worm Fly
axonogenesis GO:0007409 152 0.191
pericardium morphogenesis GO:0003344 1 0.189
cell morphogenesis involved in differentiation GO:0000904 195 0.189
myeloid cell differentiation GO:0030099 86 0.187
Zebrafish
hematopoietic stem cell differentiation GO:0060218 20 0.187
Zebrafish
heart looping GO:0001947 94 0.185
response to organic cyclic compound GO:0014070 51 0.184
generation of neurons GO:0048699 385 0.184
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.183
regulation of cellular protein metabolic process GO:0032268 52 0.181
negative regulation of axon extension GO:0030517 7 0.179
cell projection organization GO:0030030 284 0.179
Zebrafish
positive regulation of transport GO:0051050 2 0.178
regulation of catalytic activity GO:0050790 55 0.176
morphogenesis of embryonic epithelium GO:0016331 30 0.175
Zebrafish
immune system development GO:0002520 191 0.175
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.174
Worm Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.174
regulation of mapk cascade GO:0043408 14 0.173
renal tubule morphogenesis GO:0061333 1 0.171
Fly
positive regulation of striated muscle tissue development GO:0045844 1 0.171
protein import into nucleus GO:0006606 3 0.168
specification of organ identity GO:0010092 2 0.167
cellular response to estradiol stimulus GO:0071392 1 0.167
camera type eye morphogenesis GO:0048593 108 0.166
Zebrafish
cell migration involved in heart development GO:0060973 22 0.166
nitrogen compound metabolic process GO:0006807 319 0.166
Zebrafish Worm Fly
positive regulation of chromatin modification GO:1903310 1 0.165
gastrulation GO:0007369 208 0.164
Zebrafish Worm Fly
epithelial tube formation GO:0072175 19 0.163
Zebrafish
gall bladder development GO:0061010 1 0.160
embryonic skeletal joint development GO:0072498 3 0.160
intracellular signal transduction GO:0035556 85 0.160
pathway restricted smad protein phosphorylation GO:0060389 1 0.159
embryonic skeletal joint morphogenesis GO:0060272 3 0.159
spinal cord radial glial cell differentiation GO:0021531 2 0.158
heart field specification GO:0003128 1 0.158
protein import GO:0017038 3 0.157
ear morphogenesis GO:0042471 64 0.157
multicellular organismal reproductive process GO:0048609 35 0.156
Worm
stem cell proliferation GO:0072089 4 0.155
mitotic cell cycle GO:0000278 64 0.155
inner ear development GO:0048839 126 0.154
Zebrafish
endocardial cushion formation GO:0003272 2 0.153
positive regulation of cytokine production GO:0001819 2 0.151
positive regulation of chemotaxis GO:0050921 5 0.149
multicellular organism reproduction GO:0032504 35 0.149
Worm
regulation of phosphorus metabolic process GO:0051174 43 0.149
regulation of intracellular signal transduction GO:1902531 57 0.148
regulation of synapse organization GO:0050807 3 0.148
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.147
fertilization GO:0009566 3 0.147
neural crest cell migration GO:0001755 42 0.145
regulation of epithelial cell proliferation GO:0050678 3 0.144
positive regulation of rna metabolic process GO:0051254 59 0.144
Zebrafish Worm Fly
regulation of cell death GO:0010941 103 0.142
primary neural tube formation GO:0014020 1 0.142
positive regulation of endothelial cell proliferation GO:0001938 1 0.141
regulation of phosphate metabolic process GO:0019220 43 0.141
heart rudiment development GO:0003313 8 0.141
negative regulation of axonogenesis GO:0050771 7 0.140
regulation of reproductive process GO:2000241 4 0.140
transcription dna templated GO:0006351 181 0.137
Zebrafish Worm Fly
negative regulation of muscle organ development GO:0048635 5 0.137
response to growth factor GO:0070848 39 0.137
dorsal ventral neural tube patterning GO:0021904 1 0.136
negative regulation of endodermal cell differentiation GO:1903225 8 0.136
eye development GO:0001654 277 0.136
Zebrafish
negative regulation of cell differentiation GO:0045596 46 0.133
Zebrafish
cardiac atrium morphogenesis GO:0003209 2 0.132
epithelium regeneration GO:1990399 14 0.132
mesoderm formation GO:0001707 43 0.132
Zebrafish Worm Fly
single organism organelle organization GO:1902589 199 0.130
Fly
somite development GO:0061053 96 0.129
positive regulation of epithelial cell differentiation GO:0030858 2 0.129
Zebrafish
autonomic nervous system development GO:0048483 19 0.129
nephron morphogenesis GO:0072028 2 0.128
tissue regeneration GO:0042246 74 0.128
positive regulation of jun kinase activity GO:0043507 2 0.127
positive regulation of endothelial cell migration GO:0010595 2 0.127
single organism transport GO:0044765 206 0.126
muscle structure development GO:0061061 196 0.125
Fly
positive regulation of developmental process GO:0051094 50 0.124
Zebrafish
single organism behavior GO:0044708 24 0.123
regulation of programmed cell death GO:0043067 101 0.122
positive regulation of macromolecule metabolic process GO:0010604 93 0.122
Zebrafish Worm Fly
pericardium development GO:0060039 1 0.121
chromosome organization GO:0051276 31 0.121
morphogenesis of a branching epithelium GO:0061138 16 0.121
protein phosphorylation GO:0006468 47 0.121
response to vitamin GO:0033273 3 0.119
forebrain neuron development GO:0021884 7 0.118
Zebrafish
positive regulation of histone deacetylation GO:0031065 1 0.117
cellular response to endogenous stimulus GO:0071495 68 0.117
facial nerve development GO:0021561 3 0.117
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.117
epithalamus development GO:0021538 10 0.117
regulation of cellular amino acid metabolic process GO:0006521 0 0.117
negative regulation of biosynthetic process GO:0009890 55 0.115
septum transversum development GO:0003343 4 0.115
Zebrafish
myotube differentiation GO:0014902 45 0.114
cellular nitrogen compound biosynthetic process GO:0044271 218 0.114
Zebrafish Worm Fly
establishment of protein localization to organelle GO:0072594 4 0.114
ectodermal placode development GO:0071696 37 0.113
Zebrafish
cell projection morphogenesis GO:0048858 244 0.113
cellular response to stress GO:0033554 62 0.113
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.112
regulation of mitotic cell cycle GO:0007346 25 0.112
regulation of protein transport GO:0051223 3 0.112
positive regulation of cellular protein metabolic process GO:0032270 22 0.112
pharyngeal system development GO:0060037 18 0.111
erythrocyte homeostasis GO:0034101 55 0.111
Zebrafish
regulation of cellular component organization GO:0051128 86 0.110
digestive tract morphogenesis GO:0048546 231 0.109
Zebrafish Worm Fly
response to estradiol GO:0032355 6 0.107
determination of dorsal identity GO:0048263 13 0.107
regulation of cellular ketone metabolic process GO:0010565 7 0.106
cell fate specification GO:0001708 68 0.105
Worm
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.105
cell morphogenesis GO:0000902 289 0.102
regulation of tube size GO:0035150 2 0.101
embryonic digestive tract development GO:0048566 4 0.101
response to endogenous stimulus GO:0009719 83 0.101
exocrine system development GO:0035272 28 0.101
Zebrafish Fly
larval development GO:0002164 2 0.100
cellular amine metabolic process GO:0044106 2 0.099
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.098
Zebrafish Worm Fly
mitotic cell cycle process GO:1903047 48 0.098
patterning of blood vessels GO:0001569 15 0.098
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.097
regulation of nervous system development GO:0051960 90 0.096
Zebrafish
axon guidance GO:0007411 86 0.096
regulation of localization GO:0032879 104 0.096
axon development GO:0061564 166 0.096
Zebrafish
mesenchyme development GO:0060485 127 0.095
Zebrafish
odontogenesis of dentin containing tooth GO:0042475 1 0.095
cell cycle process GO:0022402 53 0.094
positive regulation of muscle cell differentiation GO:0051149 1 0.093
multi organism process GO:0051704 134 0.093
Worm
response to glucocorticoid GO:0051384 1 0.093
regulation of gene expression GO:0010468 265 0.093
Zebrafish Worm Fly
behavior GO:0007610 74 0.092
Zebrafish Worm
positive regulation of cell cycle GO:0045787 3 0.091
nuclear division GO:0000280 23 0.091
developmental growth GO:0048589 166 0.091
epithelial cell morphogenesis GO:0003382 2 0.089
regulation of blood vessel size GO:0050880 2 0.089
sensory epithelium regeneration GO:0070654 14 0.088
embryonic digestive tract morphogenesis GO:0048557 3 0.088
oocyte maturation GO:0001556 4 0.087
apoptotic process GO:0006915 116 0.087
multicellular organismal metabolic process GO:0044236 2 0.087
neuron projection morphogenesis GO:0048812 161 0.087
nucleobase containing compound metabolic process GO:0006139 274 0.087
Zebrafish Worm Fly
cardiac conduction system development GO:0003161 1 0.085
aging GO:0007568 2 0.085
regulation of nitrogen compound metabolic process GO:0051171 251 0.085
Zebrafish Worm Fly
small molecule metabolic process GO:0044281 77 0.084
forebrain generation of neurons GO:0021872 14 0.084
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.083
positive regulation of histone modification GO:0031058 1 0.083
cellular component morphogenesis GO:0032989 336 0.082
establishment of localization GO:0051234 244 0.082
positive regulation of cellular catabolic process GO:0031331 3 0.081
positive regulation of cell differentiation GO:0045597 30 0.081
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.080
g1 s transition of mitotic cell cycle GO:0000082 1 0.080
hypophysis morphogenesis GO:0048850 5 0.080
regulation of organ morphogenesis GO:2000027 35 0.079
negative regulation of mitosis GO:0045839 3 0.077
appendage development GO:0048736 80 0.077
Zebrafish
central nervous system development GO:0007417 387 0.077
Zebrafish
response to corticosteroid GO:0031960 1 0.076
endodermal cell fate specification GO:0001714 17 0.076
organelle fission GO:0048285 23 0.076
response to other organism GO:0051707 97 0.076
heterocycle biosynthetic process GO:0018130 215 0.076
Zebrafish Worm Fly
cytoskeleton organization GO:0007010 96 0.075
Fly
bmp signaling pathway GO:0030509 52 0.075
chondrocyte development GO:0002063 4 0.075
regulation of bone mineralization GO:0030500 2 0.075
regulation of cytokine production GO:0001817 3 0.074
protein localization to nucleus GO:0034504 3 0.074
osteoblast differentiation GO:0001649 5 0.074
convergent extension GO:0060026 118 0.073
sex determination GO:0007530 1 0.072
erythrocyte differentiation GO:0030218 54 0.072
Zebrafish
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.072
dorsal ventral pattern formation GO:0009953 125 0.072
negative regulation of mitotic cell cycle GO:0045930 11 0.071
kidney vasculature morphogenesis GO:0061439 1 0.071
covalent chromatin modification GO:0016569 20 0.071
cranial nerve morphogenesis GO:0021602 15 0.071
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.070
positive regulation of epithelial cell migration GO:0010634 2 0.070
regulation of stem cell proliferation GO:0072091 2 0.070
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.070
response to organic substance GO:0010033 153 0.070
cell proliferation involved in heart morphogenesis GO:0061323 2 0.070
mesoderm development GO:0007498 88 0.070
Zebrafish Worm Fly
artery morphogenesis GO:0048844 14 0.069
Zebrafish
endocrine pancreas development GO:0031018 27 0.069
Zebrafish
mediolateral intercalation GO:0060031 3 0.069
neuron projection regeneration GO:0031102 16 0.068
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.068
Zebrafish Worm Fly
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.068
endocardial cushion morphogenesis GO:0003203 3 0.066
otic vesicle morphogenesis GO:0071600 34 0.066
kidney epithelium development GO:0072073 23 0.066
cellular amino acid metabolic process GO:0006520 7 0.065
negative chemotaxis GO:0050919 1 0.065
branching morphogenesis of an epithelial tube GO:0048754 15 0.065
adherens junction organization GO:0034332 4 0.065
pancreas development GO:0031016 84 0.064
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.064
heart rudiment formation GO:0003315 5 0.064
macromolecule localization GO:0033036 54 0.063
otic vesicle development GO:0071599 42 0.063
endocardial cushion development GO:0003197 6 0.063
spermatogenesis GO:0007283 7 0.063
positive regulation of response to stimulus GO:0048584 80 0.063
neural plate development GO:0001840 10 0.062
Zebrafish
bmp signaling pathway involved in heart jogging GO:0003303 14 0.062
cytosolic calcium ion transport GO:0060401 3 0.062
regulation of metabolic process GO:0019222 359 0.062
Zebrafish Worm Fly
positive regulation of protein deacetylation GO:0090312 1 0.061
exocrine pancreas development GO:0031017 28 0.060
Zebrafish
pronephros development GO:0048793 69 0.060
central nervous system neuron differentiation GO:0021953 74 0.060
Zebrafish
regulation of muscle organ development GO:0048634 9 0.060
Fly
negative regulation of developmental process GO:0051093 65 0.059
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.059
single organism metabolic process GO:0044710 217 0.058
liver development GO:0001889 96 0.057
regulation of intracellular protein transport GO:0033157 3 0.056
regulation of developmental growth GO:0048638 38 0.056
chondrocyte differentiation GO:0002062 7 0.056
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.056
endodermal cell fate commitment GO:0001711 18 0.056
regulation of cell cycle GO:0051726 52 0.055
Zebrafish
glomerulus vasculature development GO:0072012 2 0.055
regulation of carbohydrate metabolic process GO:0006109 4 0.055
regulation of epithelial to mesenchymal transition GO:0010717 3 0.054
regulation of cell development GO:0060284 100 0.054
Zebrafish
negative regulation of striated muscle tissue development GO:0045843 2 0.054
regulation of response to external stimulus GO:0032101 31 0.054
response to wounding GO:0009611 116 0.054
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.054
Fly
regulation of cell activation GO:0050865 1 0.053
mesodermal cell migration GO:0008078 12 0.053
regulation of organ growth GO:0046620 3 0.053
negative regulation of metabolic process GO:0009892 86 0.053
Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.052
forebrain cell migration GO:0021885 1 0.052
neural tube formation GO:0001841 16 0.052
nuclear import GO:0051170 3 0.052
regulation of cell size GO:0008361 29 0.052
organonitrogen compound metabolic process GO:1901564 74 0.052
cardiac atrium development GO:0003230 4 0.052
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.052
cellular response to starvation GO:0009267 1 0.052
regulation of phosphorylation GO:0042325 26 0.052
cellular response to external stimulus GO:0071496 2 0.051
thrombocyte differentiation GO:0002574 4 0.051
pharyngeal muscle development GO:0043282 4 0.051
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.051
cell proliferation GO:0008283 80 0.051
negative regulation of neurogenesis GO:0050768 20 0.051
Zebrafish
morphogenesis of a branching structure GO:0001763 21 0.051
regulation of canonical wnt signaling pathway GO:0060828 34 0.051
cellular response to organic substance GO:0071310 105 0.050
kidney vasculature development GO:0061440 2 0.050
regulation of molecular function GO:0065009 70 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.050
regulation of cartilage development GO:0061035 7 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.050
Zebrafish Worm Fly
gamete generation GO:0007276 33 0.050
peptidyl threonine phosphorylation GO:0018107 1 0.050
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.049
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.049
cell type specific apoptotic process GO:0097285 22 0.049
radial glial cell differentiation GO:0060019 2 0.049
epithelial tube morphogenesis GO:0060562 148 0.049
Zebrafish Fly
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.049
establishment of epithelial cell polarity GO:0090162 2 0.049
regulation of purine nucleotide metabolic process GO:1900542 17 0.048
epithelial to mesenchymal transition GO:0001837 21 0.048
cellular macromolecule localization GO:0070727 21 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.047
central nervous system neuron development GO:0021954 29 0.047
Zebrafish
microtubule based process GO:0007017 60 0.047
polarized epithelial cell differentiation GO:0030859 4 0.047
Zebrafish
i kappab kinase nf kappab signaling GO:0007249 4 0.047
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.047
diencephalon morphogenesis GO:0048852 5 0.047
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.046
regulation of heart growth GO:0060420 2 0.046
regulation of cell proliferation GO:0042127 37 0.046
blood vessel endothelial cell migration GO:0043534 18 0.046
regulation of growth GO:0040008 42 0.046
nephron development GO:0072006 31 0.046
embryonic eye morphogenesis GO:0048048 30 0.046
regulation of protein targeting GO:1903533 2 0.046
transcription from rna polymerase ii promoter GO:0006366 80 0.046
Worm Fly
cell cycle g1 s phase transition GO:0044843 1 0.045
positive regulation of striated muscle cell differentiation GO:0051155 1 0.045
somatic stem cell maintenance GO:0035019 1 0.045
thymus development GO:0048538 10 0.045

twist1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org