Danio rerio

0 known processes

pcdh1a10

protocadherin 1 alpha 10

(Aliases: DrPcdh1ac)

pcdh1a10 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein localization to nucleus GO:0034504 3 0.128
nuclear transport GO:0051169 4 0.072
nucleocytoplasmic transport GO:0006913 4 0.057
aging GO:0007568 2 0.055
establishment of protein localization to organelle GO:0072594 4 0.043
protein targeting to nucleus GO:0044744 3 0.042
maintenance of location GO:0051235 4 0.040
regulation of multicellular organism growth GO:0040014 4 0.039
protein import into nucleus GO:0006606 3 0.039
organic substance biosynthetic process GO:1901576 289 0.039
larval development GO:0002164 2 0.039
multicellular organism growth GO:0035264 4 0.036
protein import GO:0017038 3 0.035
regulation of protein localization to nucleus GO:1900180 2 0.035
organic cyclic compound metabolic process GO:1901360 301 0.033
single organism nuclear import GO:1902593 3 0.033
signal transduction GO:0007165 455 0.032
stem cell maintenance GO:0019827 4 0.031
positive regulation of transport GO:0051050 2 0.031
nuclear import GO:0051170 3 0.031
regulation of protein transport GO:0051223 3 0.031
regulation of establishment of protein localization GO:0070201 4 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
amine metabolic process GO:0009308 2 0.030
regulation of synapse organization GO:0050807 3 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
regulation of dna templated transcription in response to stress GO:0043620 0 0.029
peptidyl serine phosphorylation GO:0018105 1 0.029
cellular biosynthetic process GO:0044249 286 0.028
regulation of meiotic cell cycle GO:0051445 1 0.028
oxoacid metabolic process GO:0043436 31 0.028
adult behavior GO:0030534 2 0.028
digestive system development GO:0055123 289 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
digestive tract morphogenesis GO:0048546 231 0.027
response to drug GO:0042493 3 0.027
meiotic nuclear division GO:0007126 4 0.026
response to biotic stimulus GO:0009607 97 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of reproductive process GO:2000241 4 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
transcription dna templated GO:0006351 181 0.025
peptidyl serine modification GO:0018209 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.024
tissue remodeling GO:0048771 4 0.024
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.024
regulation of metal ion transport GO:0010959 4 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
cellular macromolecule metabolic process GO:0044260 391 0.023
positive regulation of cell cycle GO:0045787 3 0.023
nucleic acid metabolic process GO:0090304 244 0.022
response to external stimulus GO:0009605 264 0.022
regulation of protein catabolic process GO:0042176 1 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
autophagy GO:0006914 4 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
regulation of dna replication GO:0006275 3 0.021
regulation of protein complex assembly GO:0043254 3 0.021
cellular response to nutrient levels GO:0031669 2 0.021
gastrulation GO:0007369 208 0.021
positive regulation of catabolic process GO:0009896 4 0.021
meiotic cell cycle process GO:1903046 3 0.021
heterocycle metabolic process GO:0046483 290 0.021
rna metabolic process GO:0016070 219 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
single organism metabolic process GO:0044710 217 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
response to chemical GO:0042221 320 0.021
determination of bilateral symmetry GO:0009855 204 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
gene expression GO:0010467 252 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of metabolic process GO:0019222 359 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of mrna processing GO:0050684 3 0.020
regulation of autophagy GO:0010506 3 0.020
cellular component movement GO:0006928 335 0.020
regulation of binding GO:0051098 3 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
cellular response to external stimulus GO:0071496 2 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
protein acetylation GO:0006473 2 0.020
rna biosynthetic process GO:0032774 181 0.020
regulation of gene expression GO:0010468 265 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
regulation of biological quality GO:0065008 263 0.019
cellular response to reactive oxygen species GO:0034614 2 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of primary metabolic process GO:0080090 311 0.019
cellular protein catabolic process GO:0044257 4 0.019
sensory organ development GO:0007423 393 0.019
organic acid metabolic process GO:0006082 31 0.019
multi organism process GO:0051704 134 0.019
regulation of signaling GO:0023051 235 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
regulation of response to nutrient levels GO:0032107 1 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
regulation of response to stimulus GO:0048583 269 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
head development GO:0060322 303 0.019
phagocytosis GO:0006909 3 0.019
negative regulation of intracellular transport GO:0032387 3 0.018
biosynthetic process GO:0009058 294 0.018
nucleic acid templated transcription GO:0097659 181 0.018
response to stress GO:0006950 263 0.018
stem cell division GO:0017145 1 0.018
cell migration GO:0016477 237 0.018
blood vessel development GO:0001568 246 0.018
cell substrate adhesion GO:0031589 4 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.018
blood vessel morphogenesis GO:0048514 216 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of blood pressure GO:0008217 1 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
somatic stem cell maintenance GO:0035019 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
cellular response to starvation GO:0009267 1 0.018
lipid storage GO:0019915 1 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
immune system process GO:0002376 241 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
regulation of rna metabolic process GO:0051252 224 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
digestive tract development GO:0048565 265 0.017
response to hydrogen peroxide GO:0042542 3 0.017
single organism organelle organization GO:1902589 199 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
membrane invagination GO:0010324 1 0.017
vasculature development GO:0001944 278 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
negative regulation of protein import into nucleus GO:0042308 2 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
regulation of multicellular organismal development GO:2000026 223 0.016
regulation of biosynthetic process GO:0009889 250 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
regulation of signal transduction GO:0009966 225 0.016
cell matrix adhesion GO:0007160 4 0.016
negative regulation of biological process GO:0048519 304 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
response to organic substance GO:0010033 153 0.016
regulation of cell communication GO:0010646 232 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
sensory organ morphogenesis GO:0090596 200 0.016
protein acylation GO:0043543 3 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
cell motility GO:0048870 244 0.016
regulation of synapse assembly GO:0051963 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
negative regulation of mapk cascade GO:0043409 4 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
regulation of cell activation GO:0050865 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of blood vessel size GO:0050880 2 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of transcription dna templated GO:0006355 213 0.015
regulation of oocyte development GO:0060281 3 0.015
response to other organism GO:0051707 97 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
cellular protein metabolic process GO:0044267 129 0.015
protein metabolic process GO:0019538 183 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regionalization GO:0003002 274 0.015
system process GO:0003008 185 0.015
nuclear export GO:0051168 1 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
tube morphogenesis GO:0035239 349 0.015
regulation of protein binding GO:0043393 3 0.015
antimicrobial humoral response GO:0019730 2 0.015
positive regulation of translation GO:0045727 1 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
positive regulation of biological process GO:0048518 253 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
positive regulation of reproductive process GO:2000243 2 0.014
negative regulation of protein localization to nucleus GO:1900181 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
oocyte maturation GO:0001556 4 0.014
specification of symmetry GO:0009799 204 0.014
determination of left right symmetry GO:0007368 179 0.014
meiotic chromosome segregation GO:0045132 3 0.014
gtp metabolic process GO:0046039 4 0.014
negative regulation of catabolic process GO:0009895 3 0.014
olfactory lobe development GO:0021988 4 0.014
response to wounding GO:0009611 116 0.014
angiogenesis GO:0001525 158 0.014
intracellular signal transduction GO:0035556 85 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
brain development GO:0007420 293 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
response to external biotic stimulus GO:0043207 97 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
secondary metabolic process GO:0019748 3 0.014
gtp catabolic process GO:0006184 2 0.013
protein polymerization GO:0051258 4 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
muscle structure development GO:0061061 196 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
programmed cell death GO:0012501 119 0.013
embryonic heart tube development GO:0035050 133 0.013
small molecule metabolic process GO:0044281 77 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
single organism transport GO:0044765 206 0.013
macroautophagy GO:0016236 1 0.013
negative regulation of cellular process GO:0048523 283 0.013
sequestering of metal ion GO:0051238 3 0.013
regulation of localization GO:0032879 104 0.013
cytokinesis GO:0000910 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
protein complex disassembly GO:0043241 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
central nervous system development GO:0007417 387 0.013
ameboidal type cell migration GO:0001667 143 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
sequestering of calcium ion GO:0051208 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
regulation of protein targeting GO:1903533 2 0.013
establishment of localization GO:0051234 244 0.013
golgi vesicle transport GO:0048193 3 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
phagocytosis engulfment GO:0006911 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
negative regulation of kinase activity GO:0033673 4 0.012
stem cell proliferation GO:0072089 4 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
regulation of developmental process GO:0050793 247 0.012
negative regulation of cytokine production GO:0001818 1 0.012
smooth muscle contraction GO:0006939 2 0.012
chordate embryonic development GO:0043009 271 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of wound healing GO:0061041 2 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
camera type eye development GO:0043010 222 0.012
regulation of cytokine production GO:0001817 3 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
lipid homeostasis GO:0055088 3 0.012
liver development GO:0001889 96 0.012
neuron differentiation GO:0030182 353 0.012
embryonic organ development GO:0048568 381 0.012
positive regulation of cellular process GO:0048522 201 0.012
germ line stem cell maintenance GO:0030718 2 0.012
transport GO:0006810 220 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
anterior posterior pattern specification GO:0009952 152 0.012
response to uv GO:0009411 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
defense response to fungus GO:0050832 2 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
positive regulation of multi organism process GO:0043902 3 0.012
catecholamine metabolic process GO:0006584 2 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
compound eye development GO:0048749 2 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
positive regulation of cytokine production GO:0001819 2 0.012
single organism localization GO:1902578 225 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
cellular protein modification process GO:0006464 100 0.012
heart morphogenesis GO:0003007 156 0.012
protein localization to plasma membrane GO:0072659 1 0.012
protein homooligomerization GO:0051260 3 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
wound healing GO:0042060 90 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
membrane fusion GO:0061025 2 0.012
cellular component biogenesis GO:0044085 178 0.012
skeletal system development GO:0001501 181 0.012
actin filament polymerization GO:0030041 2 0.011
neuron development GO:0048666 262 0.011
single organism membrane fusion GO:0044801 2 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
negative regulation of autophagy GO:0010507 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
rna localization GO:0006403 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of calcium ion transport GO:0051924 2 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of transporter activity GO:0032409 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
macromolecule modification GO:0043412 111 0.011
regulation of tube size GO:0035150 2 0.011
negative regulation of signaling GO:0023057 96 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
negative regulation of nuclear division GO:0051784 3 0.011
somatic muscle development GO:0007525 4 0.011
lymphocyte proliferation GO:0046651 1 0.011
eye development GO:0001654 277 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
negative regulation of cell communication GO:0010648 96 0.011
developmental growth GO:0048589 166 0.011
hepaticobiliary system development GO:0061008 98 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
heart looping GO:0001947 94 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
atp catabolic process GO:0006200 4 0.011
homeostatic process GO:0042592 142 0.011
positive regulation of cell activation GO:0050867 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of photoreceptor cell differentiation GO:0046532 2 0.010
cellular localization GO:0051641 97 0.010
macromolecular complex disassembly GO:0032984 1 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
lateral line system development GO:0048925 76 0.010
cognition GO:0050890 1 0.010
regulation of cell differentiation GO:0045595 142 0.010
tube closure GO:0060606 1 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
ion transport GO:0006811 114 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
specification of axis polarity GO:0065001 4 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
regulation of gtpase activity GO:0043087 2 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
eye morphogenesis GO:0048592 144 0.010
connective tissue development GO:0061448 99 0.010
response to topologically incorrect protein GO:0035966 2 0.010
positive regulation of secretion GO:0051047 1 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
regulation of response to oxidative stress GO:1902882 2 0.010

pcdh1a10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cardiovascular system disease DOID:1287 0 0.019
musculoskeletal system disease DOID:17 0 0.019
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.013
myopathy DOID:423 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.010