Danio rerio

45 known processes

smpd2

sphingomyelin phosphodiesterase 2, neutral

(Aliases: NSMase)

smpd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.064
larval development GO:0002164 2 0.052
multicellular organism growth GO:0035264 4 0.041
aging GO:0007568 2 0.034
i kappab kinase nf kappab signaling GO:0007249 4 0.033
endosomal transport GO:0016197 2 0.032
phagocytosis GO:0006909 3 0.031
transport GO:0006810 220 0.031
maintenance of location GO:0051235 4 0.031
regulation of multicellular organism growth GO:0040014 4 0.029
establishment of localization GO:0051234 244 0.028
adult behavior GO:0030534 2 0.027
positive regulation of transport GO:0051050 2 0.026
regulation of biological quality GO:0065008 263 0.025
amine metabolic process GO:0009308 2 0.025
single organism localization GO:1902578 225 0.024
cognition GO:0050890 1 0.023
cellular amine metabolic process GO:0044106 2 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
lipid storage GO:0019915 1 0.022
regulation of protein complex assembly GO:0043254 3 0.022
amino acid transport GO:0006865 2 0.021
organic acid metabolic process GO:0006082 31 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
autophagy GO:0006914 4 0.020
cellular component movement GO:0006928 335 0.019
positive regulation of cellular process GO:0048522 201 0.019
protein localization to nucleus GO:0034504 3 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
leukocyte proliferation GO:0070661 1 0.019
tube morphogenesis GO:0035239 349 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of cell activation GO:0050865 1 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
single organism transport GO:0044765 206 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
regulation of response to stimulus GO:0048583 269 0.018
stem cell proliferation GO:0072089 4 0.018
mitochondrion organization GO:0007005 4 0.018
regulation of protein polymerization GO:0032271 2 0.018
membrane invagination GO:0010324 1 0.017
exocytosis GO:0006887 1 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
regulation of synapse organization GO:0050807 3 0.017
response to stress GO:0006950 263 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
dicarboxylic acid transport GO:0006835 1 0.017
oxoacid metabolic process GO:0043436 31 0.017
cytokinesis GO:0000910 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
neuromuscular process controlling balance GO:0050885 3 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
signal transduction GO:0007165 455 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
positive regulation of cell cycle GO:0045787 3 0.016
phagocytosis engulfment GO:0006911 1 0.016
protein import GO:0017038 3 0.016
chemosensory behavior GO:0007635 1 0.016
regulation of synapse assembly GO:0051963 3 0.016
regulation of cytokine production GO:0001817 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
system process GO:0003008 185 0.015
brain development GO:0007420 293 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
regulation of reproductive process GO:2000241 4 0.015
female sex differentiation GO:0046660 4 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
biosynthetic process GO:0009058 294 0.015
heterocycle metabolic process GO:0046483 290 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
positive regulation of biological process GO:0048518 253 0.015
positive regulation of catabolic process GO:0009896 4 0.015
nucleic acid metabolic process GO:0090304 244 0.015
nuclear transport GO:0051169 4 0.015
tube closure GO:0060606 1 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
golgi vesicle transport GO:0048193 3 0.015
rna metabolic process GO:0016070 219 0.015
organic substance biosynthetic process GO:1901576 289 0.015
interspecies interaction between organisms GO:0044419 4 0.015
protein complex disassembly GO:0043241 1 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.014
cellular ketone metabolic process GO:0042180 11 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of cell projection assembly GO:0060491 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
response to chemical GO:0042221 320 0.014
regulation of cell shape GO:0008360 1 0.014
ion transport GO:0006811 114 0.014
positive regulation of secretion GO:0051047 1 0.014
somatic muscle development GO:0007525 4 0.014
gtp metabolic process GO:0046039 4 0.014
regulation of metabolic process GO:0019222 359 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
nuclear import GO:0051170 3 0.014
regulation of signaling GO:0023051 235 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
small molecule metabolic process GO:0044281 77 0.013
transmembrane transport GO:0055085 120 0.013
negative regulation of cellular process GO:0048523 283 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
cellular component disassembly GO:0022411 1 0.013
neurotransmitter transport GO:0006836 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
peptide transport GO:0015833 1 0.013
actin filament polymerization GO:0030041 2 0.013
digestive tract morphogenesis GO:0048546 231 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
head development GO:0060322 303 0.013
gtp catabolic process GO:0006184 2 0.013
regulation of muscle contraction GO:0006937 3 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
alcohol biosynthetic process GO:0046165 2 0.013
regulation of tube size GO:0035150 2 0.013
gene expression GO:0010467 252 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
response to carbohydrate GO:0009743 3 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of mrna processing GO:0050684 3 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
response to hydrogen peroxide GO:0042542 3 0.012
single organism nuclear import GO:1902593 3 0.012
vasculature development GO:0001944 278 0.012
digestive system development GO:0055123 289 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
locomotion GO:0040011 313 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
atp catabolic process GO:0006200 4 0.012
positive regulation of cell activation GO:0050867 1 0.012
regulation of exocytosis GO:0017157 1 0.012
protein polymerization GO:0051258 4 0.012
response to monosaccharide GO:0034284 3 0.012
primary neural tube formation GO:0014020 1 0.012
cellular biosynthetic process GO:0044249 286 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
response to glucocorticoid GO:0051384 1 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
long chain fatty acid metabolic process GO:0001676 1 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
negative regulation of catabolic process GO:0009895 3 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
sensory organ morphogenesis GO:0090596 200 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
vacuolar transport GO:0007034 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
organelle organization GO:0006996 227 0.011
tissue remodeling GO:0048771 4 0.011
response to hexose GO:0009746 3 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
response to corticosteroid GO:0031960 1 0.011
response to glucose GO:0009749 3 0.011
embryonic organ development GO:0048568 381 0.011
ion transmembrane transport GO:0034220 91 0.011
cellular component biogenesis GO:0044085 178 0.011
digestive tract development GO:0048565 265 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
response to ketone GO:1901654 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
immune system process GO:0002376 241 0.011
actin filament based movement GO:0030048 1 0.011
protein metabolic process GO:0019538 183 0.011
hormone secretion GO:0046879 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
response to wounding GO:0009611 116 0.011
neurotransmitter secretion GO:0007269 2 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
homeostatic process GO:0042592 142 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of primary metabolic process GO:0080090 311 0.011
membrane fusion GO:0061025 2 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
regulation of ph GO:0006885 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
rna localization GO:0006403 4 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
growth GO:0040007 174 0.011
cell morphogenesis GO:0000902 289 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
mononuclear cell proliferation GO:0032943 1 0.010
regulation of binding GO:0051098 3 0.010
cellular component morphogenesis GO:0032989 336 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
single organism metabolic process GO:0044710 217 0.010
macromolecular complex disassembly GO:0032984 1 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
central nervous system development GO:0007417 387 0.010
stem cell maintenance GO:0019827 4 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
regulation of protein targeting GO:1903533 2 0.010
synaptic vesicle localization GO:0097479 1 0.010
neuron differentiation GO:0030182 353 0.010
protein secretion GO:0009306 1 0.010
single organism membrane fusion GO:0044801 2 0.010
regulation of filopodium assembly GO:0051489 2 0.010
protein import into nucleus GO:0006606 3 0.010
lateral inhibition GO:0046331 1 0.010
protein homooligomerization GO:0051260 3 0.010
response to nutrient GO:0007584 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
negative regulation of defense response GO:0031348 2 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of organelle assembly GO:1902115 4 0.010
regulation of protein catabolic process GO:0042176 1 0.010

smpd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.017
nervous system disease DOID:863 0 0.014