Danio rerio

0 known processes

dennd2d

DENN/MADD domain containing 2D

(Aliases: zgc:103487)

dennd2d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of location GO:0051235 4 0.055
larval development GO:0002164 2 0.054
positive regulation of transport GO:0051050 2 0.043
cognition GO:0050890 1 0.042
meiotic cell cycle process GO:1903046 3 0.039
spindle assembly GO:0051225 2 0.039
lipid storage GO:0019915 1 0.038
lateral inhibition GO:0046331 1 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.032
meiotic nuclear division GO:0007126 4 0.032
rna metabolic process GO:0016070 219 0.031
aging GO:0007568 2 0.030
regulation of binding GO:0051098 3 0.030
developmental programmed cell death GO:0010623 4 0.030
central nervous system development GO:0007417 387 0.030
nuclear export GO:0051168 1 0.029
regulation of biosynthetic process GO:0009889 250 0.029
regulation of cell activation GO:0050865 1 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
establishment of localization GO:0051234 244 0.028
phagocytosis GO:0006909 3 0.027
cell morphogenesis GO:0000902 289 0.027
regulation of cytokine production GO:0001817 3 0.027
cellular amine metabolic process GO:0044106 2 0.026
response to drug GO:0042493 3 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
amine metabolic process GO:0009308 2 0.024
heart development GO:0007507 313 0.024
organic substance biosynthetic process GO:1901576 289 0.024
single organism organelle organization GO:1902589 199 0.024
transport GO:0006810 220 0.023
nuclear transport GO:0051169 4 0.023
transcription dna templated GO:0006351 181 0.023
positive regulation of map kinase activity GO:0043406 3 0.023
cellular protein catabolic process GO:0044257 4 0.023
biosynthetic process GO:0009058 294 0.022
multicellular organism growth GO:0035264 4 0.022
regulation of protein complex assembly GO:0043254 3 0.021
immune system process GO:0002376 241 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
response to stress GO:0006950 263 0.021
adult behavior GO:0030534 2 0.021
stem cell proliferation GO:0072089 4 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
microtubule organizing center organization GO:0031023 1 0.021
regulation of biological quality GO:0065008 263 0.020
regulation of cell communication GO:0010646 232 0.020
Human
oocyte maturation GO:0001556 4 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
rna biosynthetic process GO:0032774 181 0.020
generation of neurons GO:0048699 385 0.020
organelle organization GO:0006996 227 0.020
stem cell maintenance GO:0019827 4 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
negative regulation of cytokine production GO:0001818 1 0.019
positive regulation of cell cycle GO:0045787 3 0.019
protein polymerization GO:0051258 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
apoptotic process involved in development GO:1902742 2 0.019
neuroblast proliferation GO:0007405 2 0.019
centrosome organization GO:0051297 1 0.019
heterocycle metabolic process GO:0046483 290 0.019
Human
meiosis i GO:0007127 1 0.018
regulation of response to cytokine stimulus GO:0060759 3 0.018
neuron differentiation GO:0030182 353 0.018
cellular ketone metabolic process GO:0042180 11 0.018
response to hexose GO:0009746 3 0.018
single organism transport GO:0044765 206 0.018
cellular component movement GO:0006928 335 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cellular response to external stimulus GO:0071496 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.017
positive regulation of catabolic process GO:0009896 4 0.017
Human
tube morphogenesis GO:0035239 349 0.017
determination of bilateral symmetry GO:0009855 204 0.017
negative regulation of defense response GO:0031348 2 0.017
activation of mapk activity GO:0000187 3 0.017
leukocyte proliferation GO:0070661 1 0.017
regulation of signaling GO:0023051 235 0.017
Human
macromolecule biosynthetic process GO:0009059 227 0.016
localization of cell GO:0051674 244 0.016
single organism localization GO:1902578 225 0.016
brain development GO:0007420 293 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
oxoacid metabolic process GO:0043436 31 0.016
digestive system development GO:0055123 289 0.016
positive regulation of cytokine production GO:0001819 2 0.016
protein import GO:0017038 3 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
centrosome cycle GO:0007098 1 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
negative regulation of nuclear division GO:0051784 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
embryonic organ development GO:0048568 381 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of chromosome segregation GO:0051983 1 0.015
single organism metabolic process GO:0044710 217 0.015
Human
regulation of protein transport GO:0051223 3 0.015
head development GO:0060322 303 0.015
nucleic acid templated transcription GO:0097659 181 0.015
cellular component biogenesis GO:0044085 178 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
Human
peptide transport GO:0015833 1 0.015
meiotic chromosome segregation GO:0045132 3 0.015
stem cell division GO:0017145 1 0.015
response to topologically incorrect protein GO:0035966 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of response to stimulus GO:0048583 269 0.015
Human
camera type eye development GO:0043010 222 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
response to monosaccharide GO:0034284 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
regulation of organelle assembly GO:1902115 4 0.015
locomotion GO:0040011 313 0.015
cellular response to starvation GO:0009267 1 0.015
cellular response to organic substance GO:0071310 105 0.015
regulation of inflammatory response GO:0050727 2 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
female sex differentiation GO:0046660 4 0.014
small molecule metabolic process GO:0044281 77 0.014
Human
cellular component assembly GO:0022607 170 0.014
response to carbohydrate GO:0009743 3 0.014
positive regulation of cell activation GO:0050867 1 0.014
cellular component morphogenesis GO:0032989 336 0.014
response to chemical GO:0042221 320 0.014
specification of symmetry GO:0009799 204 0.014
regulation of blood pressure GO:0008217 1 0.014
immune system development GO:0002520 191 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
membrane fusion GO:0061025 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
Human
positive regulation of biological process GO:0048518 253 0.014
Human
cellular response to extracellular stimulus GO:0031668 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
organic acid metabolic process GO:0006082 31 0.013
nuclear import GO:0051170 3 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
Human
germ line stem cell maintenance GO:0030718 2 0.013
regulation of protein targeting GO:1903533 2 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
cellular biosynthetic process GO:0044249 286 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
cell cycle arrest GO:0007050 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
circadian sleep wake cycle sleep GO:0050802 1 0.013
b cell activation GO:0042113 2 0.013
endosomal transport GO:0016197 2 0.013
mononuclear cell proliferation GO:0032943 1 0.013
regulation of metabolic process GO:0019222 359 0.013
Human
protein localization to nucleus GO:0034504 3 0.013
chemotaxis GO:0006935 104 0.013
endosome organization GO:0007032 2 0.013
macromolecule deacylation GO:0098732 3 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of protein binding GO:0043393 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
macromolecule modification GO:0043412 111 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
death GO:0016265 121 0.013
neuron development GO:0048666 262 0.013
macromolecular complex subunit organization GO:0043933 74 0.012
autophagy GO:0006914 4 0.012
hormone transport GO:0009914 2 0.012
viral process GO:0016032 1 0.012
rna localization GO:0006403 4 0.012
single organism membrane fusion GO:0044801 2 0.012
response to ketone GO:1901654 1 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
single organism nuclear import GO:1902593 3 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of synapse assembly GO:0051963 3 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
vasculature development GO:0001944 278 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
cell projection morphogenesis GO:0048858 244 0.012
response to glucose GO:0009749 3 0.012
tissue remodeling GO:0048771 4 0.012
protein acylation GO:0043543 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of transcription dna templated GO:0006355 213 0.012
negative regulation of secretion GO:0051048 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
female gonad development GO:0008585 4 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
epithelial cell differentiation GO:0030855 116 0.012
eye morphogenesis GO:0048592 144 0.012
double strand break repair GO:0006302 3 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
regulation of synapse organization GO:0050807 3 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
signal transduction GO:0007165 455 0.012
regulation of signal transduction GO:0009966 225 0.012
Human
regulation of mitotic cell cycle embryonic GO:0009794 2 0.012
internal protein amino acid acetylation GO:0006475 2 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
Human
sensory organ morphogenesis GO:0090596 200 0.011
macroautophagy GO:0016236 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
response to organic substance GO:0010033 153 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
mitochondrion organization GO:0007005 4 0.011
wnt signaling pathway GO:0016055 80 0.011
embryonic heart tube development GO:0035050 133 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of protein polymerization GO:0032271 2 0.011
cell migration GO:0016477 237 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cytokinesis GO:0000910 3 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
protein metabolic process GO:0019538 183 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
regulation of hormone secretion GO:0046883 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
interspecies interaction between organisms GO:0044419 4 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
Human
organonitrogen compound metabolic process GO:1901564 74 0.011
Human
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
eye development GO:0001654 277 0.011
regulation of circadian rhythm GO:0042752 4 0.011
cellular protein metabolic process GO:0044267 129 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
lipid homeostasis GO:0055088 3 0.011
synaptic vesicle localization GO:0097479 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
gtp catabolic process GO:0006184 2 0.011
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
muscle structure development GO:0061061 196 0.011
cell aging GO:0007569 2 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
Human
regulation of stem cell differentiation GO:2000736 4 0.010
cellular component disassembly GO:0022411 1 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
sensory organ development GO:0007423 393 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
negative regulation of response to cytokine stimulus GO:0060761 2 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
protein acetylation GO:0006473 2 0.010
golgi vesicle transport GO:0048193 3 0.010
septum transversum development GO:0003343 4 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
protein localization to plasma membrane GO:0072659 1 0.010
glucose homeostasis GO:0042593 1 0.010
gastrulation GO:0007369 208 0.010
positive regulation of muscle organ development GO:0048636 1 0.010

dennd2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011