Danio rerio

64 known processes

bcl2

B-cell leukemia/lymphoma 2

bcl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to transition metal nanoparticle GO:1990267 28 0.810
Human Zebrafish Rat
response to metal ion GO:0010038 34 0.784
Human Zebrafish Rat
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.724
Zebrafish
negative regulation of cell division GO:0051782 4 0.722
Zebrafish
signal transduction GO:0007165 455 0.661
Human Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.649
cation homeostasis GO:0055080 33 0.645
Human Mouse
head development GO:0060322 303 0.625
Mouse Rat
cell part morphogenesis GO:0032990 246 0.614
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.550
Mouse
cellular component morphogenesis GO:0032989 336 0.548
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.537
Mouse
positive regulation of catabolic process GO:0009896 4 0.530
Worm
regulation of biological quality GO:0065008 263 0.511
Human Zebrafish Mouse
immune system development GO:0002520 191 0.438
Mouse
negative regulation of nuclear division GO:0051784 3 0.430
Zebrafish
single organism transport GO:0044765 206 0.421
Human Mouse
cell projection organization GO:0030030 284 0.416
Mouse
lymphocyte differentiation GO:0030098 9 0.394
Mouse
neuron differentiation GO:0030182 353 0.393
Mouse
response to drug GO:0042493 3 0.391
Human Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.375
Worm
nucleic acid templated transcription GO:0097659 181 0.373
response to inorganic substance GO:0010035 38 0.369
Human Zebrafish Mouse Rat
negative regulation of cellular process GO:0048523 283 0.364
regulation of signal transduction GO:0009966 225 0.359
Human Zebrafish Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.359
Worm
cellular macromolecule metabolic process GO:0044260 391 0.357
guanosine containing compound metabolic process GO:1901068 4 0.353
Worm
cell projection morphogenesis GO:0048858 244 0.345
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.340
Worm
endocrine system development GO:0035270 65 0.338
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.309
Worm
ion homeostasis GO:0050801 41 0.306
Human Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.306
positive regulation of gtp catabolic process GO:0033126 1 0.305
Worm
response to glucocorticoid GO:0051384 1 0.304
Mouse Rat
response to organic cyclic compound GO:0014070 51 0.296
Human Mouse Rat
transcription dna templated GO:0006351 181 0.293
mitochondrion organization GO:0007005 4 0.290
Mouse Worm
epithelial tube morphogenesis GO:0060562 148 0.288
Mouse
regulation of cellular metabolic process GO:0031323 320 0.280
regulation of nucleotide metabolic process GO:0006140 17 0.276
Worm
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.273
Worm
response to alkaloid GO:0043279 2 0.269
Human Rat
regulation of primary metabolic process GO:0080090 311 0.266
response to external stimulus GO:0009605 264 0.261
Human Mouse Rat
regulation of multicellular organismal process GO:0051239 277 0.257
Mouse
neuron projection morphogenesis GO:0048812 161 0.238
Mouse
positive regulation of nucleotide metabolic process GO:0045981 9 0.233
Worm
programmed cell death GO:0012501 119 0.230
sensory organ development GO:0007423 393 0.224
Mouse
response to corticosteroid GO:0031960 1 0.220
Mouse Rat
regulation of rna metabolic process GO:0051252 224 0.218
response to ionizing radiation GO:0010212 6 0.212
Mouse
myeloid cell differentiation GO:0030099 86 0.211
regulation of anatomical structure morphogenesis GO:0022603 130 0.209
Mouse Worm
single organism organelle organization GO:1902589 199 0.207
Zebrafish Mouse Worm
metal ion homeostasis GO:0055065 26 0.203
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.203
Worm
immune system process GO:0002376 241 0.202
Human Mouse
regulation of developmental process GO:0050793 247 0.199
Mouse Worm
regulation of signaling GO:0023051 235 0.199
Human Zebrafish Mouse
positive regulation of gtpase activity GO:0043547 1 0.198
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.191
Mouse
regulation of calcium ion transport GO:0051924 2 0.189
Human Mouse
divalent metal ion transport GO:0070838 20 0.189
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.188
chordate embryonic development GO:0043009 271 0.187
Zebrafish
cellular cation homeostasis GO:0030003 17 0.185
Human Mouse
multicellular organismal homeostasis GO:0048871 29 0.184
Zebrafish Mouse
peptidyl serine modification GO:0018209 2 0.182
Mouse
regulation of purine nucleotide metabolic process GO:1900542 17 0.182
Worm
skeletal system morphogenesis GO:0048705 102 0.178
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.178
Human Mouse
positive regulation of nucleotide catabolic process GO:0030813 1 0.175
Worm
calcium ion transport GO:0006816 18 0.174
Human Mouse
cell growth GO:0016049 57 0.171
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.168
Mouse
negative regulation of cell communication GO:0010648 96 0.166
Human Zebrafish Mouse
leukocyte differentiation GO:0002521 25 0.165
Mouse
establishment of localization GO:0051234 244 0.165
Human Mouse
metal ion transport GO:0030001 58 0.162
Human Mouse
homeostatic process GO:0042592 142 0.162
Human Zebrafish Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.161
Worm
cytosolic calcium ion transport GO:0060401 3 0.159
Mouse
protein metabolic process GO:0019538 183 0.156
organelle organization GO:0006996 227 0.154
Zebrafish Mouse Worm
neuron projection extension GO:1990138 45 0.154
regulation of hydrolase activity GO:0051336 28 0.152
response to copper ion GO:0046688 13 0.151
Rat
anatomical structure homeostasis GO:0060249 36 0.151
Zebrafish Mouse
calcium ion transport into cytosol GO:0060402 3 0.150
Mouse
cytoskeleton organization GO:0007010 96 0.146
Mouse
generation of neurons GO:0048699 385 0.145
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.145
Mouse
taxis GO:0042330 109 0.142
regulation of nucleic acid templated transcription GO:1903506 213 0.140
axon development GO:0061564 166 0.140
Mouse
organic substance biosynthetic process GO:1901576 289 0.139
Mouse
regulation of gtp catabolic process GO:0033124 2 0.139
Worm
apoptotic process GO:0006915 116 0.138
negative regulation of mitosis GO:0045839 3 0.138
Zebrafish
response to chemical GO:0042221 320 0.137
Human Zebrafish Mouse Rat
cell morphogenesis GO:0000902 289 0.137
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.135
Mouse
axonogenesis GO:0007409 152 0.135
Mouse
regulation of gene expression GO:0010468 265 0.135
signal transduction in absence of ligand GO:0038034 1 0.133
Human Mouse
rna metabolic process GO:0016070 219 0.132
regulation of response to stimulus GO:0048583 269 0.131
Human Zebrafish Mouse
negative regulation of cell cycle GO:0045786 14 0.130
Zebrafish Mouse
phosphorus metabolic process GO:0006793 109 0.130
Mouse Worm
rna biosynthetic process GO:0032774 181 0.129
positive regulation of peptidase activity GO:0010952 10 0.129
Zebrafish
negative regulation of sequestering of calcium ion GO:0051283 4 0.128
regulation of macromolecule metabolic process GO:0060255 317 0.127
cellular nitrogen compound metabolic process GO:0034641 290 0.124
Worm
ion transport GO:0006811 114 0.124
Human Mouse
regulation of cell death GO:0010941 103 0.122
small molecule metabolic process GO:0044281 77 0.122
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.121
regulation of rna biosynthetic process GO:2001141 213 0.120
regulation of metal ion transport GO:0010959 4 0.119
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
Worm
death GO:0016265 121 0.115
brain development GO:0007420 293 0.115
Mouse Rat
divalent inorganic cation homeostasis GO:0072507 22 0.115
Mouse
developmental growth GO:0048589 166 0.115
Mouse
muscle organ development GO:0007517 101 0.114
Mouse
negative regulation of cell death GO:0060548 60 0.113
nucleotide metabolic process GO:0009117 28 0.110
Worm
axon guidance GO:0007411 86 0.110
response to radiation GO:0009314 51 0.109
Mouse
response to stress GO:0006950 263 0.108
Human Mouse Rat
response to steroid hormone GO:0048545 35 0.107
Mouse Rat
biosynthetic process GO:0009058 294 0.106
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.106
Mouse
regulation of transcription dna templated GO:0006355 213 0.106
negative regulation of signaling GO:0023057 96 0.106
Human Zebrafish Mouse
regulation of cellular component organization GO:0051128 86 0.106
Human Zebrafish Mouse Worm
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.104
Mouse
adult behavior GO:0030534 2 0.104
cellular response to external stimulus GO:0071496 2 0.102
Mouse
single organism localization GO:1902578 225 0.100
Human Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.100
Worm
regulation of cell development GO:0060284 100 0.099
Mouse
hemopoiesis GO:0030097 183 0.099
Mouse
response to methylmercury GO:0051597 11 0.098
Zebrafish
autophagy GO:0006914 4 0.097
positive regulation of protein metabolic process GO:0051247 23 0.096
Zebrafish Mouse
tissue homeostasis GO:0001894 25 0.096
Zebrafish Mouse
regulation of protein binding GO:0043393 3 0.096
Human
neuron development GO:0048666 262 0.096
Mouse
skeletal muscle organ development GO:0060538 78 0.096
Mouse
determination of left right symmetry GO:0007368 179 0.093
negative regulation of programmed cell death GO:0043069 58 0.093
cellular protein modification process GO:0006464 100 0.093
Human Mouse
muscle cell differentiation GO:0042692 139 0.091
Mouse
positive regulation of endopeptidase activity GO:0010950 10 0.091
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.090
ion transmembrane transport GO:0034220 91 0.090
developmental growth involved in morphogenesis GO:0060560 86 0.090
regulation of programmed cell death GO:0043067 101 0.090
gland development GO:0048732 143 0.089
Zebrafish Mouse
gtp catabolic process GO:0006184 2 0.089
Worm
cellular ion homeostasis GO:0006873 17 0.089
Human Mouse
negative regulation of apoptotic process GO:0043066 55 0.088
cell death GO:0008219 121 0.088
positive regulation of cellular component biogenesis GO:0044089 3 0.088
negative regulation of signal transduction GO:0009968 94 0.087
Human Zebrafish Mouse
protein complex subunit organization GO:0071822 46 0.086
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.085
organic cyclic compound biosynthetic process GO:1901362 223 0.085
regulation of cell communication GO:0010646 232 0.084
Human Zebrafish Mouse
ribose phosphate metabolic process GO:0019693 27 0.084
Worm
embryonic organ development GO:0048568 381 0.082
neuromast development GO:0048884 46 0.082
digestive tract development GO:0048565 265 0.082
Mouse
ribonucleotide metabolic process GO:0009259 27 0.081
Worm
regulation of binding GO:0051098 3 0.081
Human
gtp metabolic process GO:0046039 4 0.081
Worm
cellular transition metal ion homeostasis GO:0046916 3 0.080
digestive tract morphogenesis GO:0048546 231 0.079
Mouse
sensory organ morphogenesis GO:0090596 200 0.078
Mouse
positive regulation of proteolysis GO:0045862 10 0.078
Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.077
Worm
sensory system development GO:0048880 76 0.077
embryo development ending in birth or egg hatching GO:0009792 271 0.076
Zebrafish Worm
regulation of cysteine type endopeptidase activity GO:2000116 21 0.073
response to organic substance GO:0010033 153 0.073
Human Zebrafish Mouse Rat
cellular component movement GO:0006928 335 0.072
Mouse
regulation of autophagy GO:0010506 3 0.071
cellular aromatic compound metabolic process GO:0006725 295 0.071
Mouse Worm
regulation of mitotic cell cycle GO:0007346 25 0.070
Zebrafish Mouse
response to abiotic stimulus GO:0009628 122 0.070
Mouse Rat
regulation of cell differentiation GO:0045595 142 0.069
Mouse
stem cell proliferation GO:0072089 4 0.068
cation transport GO:0006812 81 0.068
Human Mouse
neuron death GO:0070997 21 0.068
Human Mouse
single organism nuclear import GO:1902593 3 0.068
forebrain development GO:0030900 96 0.067
nucleobase containing compound biosynthetic process GO:0034654 205 0.067
nucleobase containing compound metabolic process GO:0006139 274 0.067
Worm
response to endogenous stimulus GO:0009719 83 0.066
Human Mouse Rat
cell surface receptor signaling pathway GO:0007166 325 0.066
Human Mouse
developmental cell growth GO:0048588 52 0.065
regulation of metabolic process GO:0019222 359 0.065
cellular response to starvation GO:0009267 1 0.064
Mouse
regulation of leukocyte differentiation GO:1902105 5 0.064
cellular chemical homeostasis GO:0055082 17 0.064
Human Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.064
Human
cell type specific apoptotic process GO:0097285 22 0.064
Human Mouse Rat
regulation of neuron differentiation GO:0045664 56 0.064
Mouse
specification of symmetry GO:0009799 204 0.063
response to cadmium ion GO:0046686 14 0.062
Zebrafish
gene expression GO:0010467 252 0.061
regulation of cell cycle process GO:0010564 20 0.061
Zebrafish Mouse
digestive system development GO:0055123 289 0.061
Mouse
epithelial cell proliferation GO:0050673 17 0.061
heterocycle biosynthetic process GO:0018130 215 0.061
cellular response to dna damage stimulus GO:0006974 24 0.059
Human
heterocycle metabolic process GO:0046483 290 0.059
Worm
compound eye development GO:0048749 2 0.059
tissue regeneration GO:0042246 74 0.059
sequestering of calcium ion GO:0051208 3 0.059
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.058
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.058
Zebrafish
internal protein amino acid acetylation GO:0006475 2 0.058
amine metabolic process GO:0009308 2 0.057
growth GO:0040007 174 0.057
Human Mouse
erythrocyte differentiation GO:0030218 54 0.056
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.055
urogenital system development GO:0001655 97 0.055
Mouse
intracellular transport GO:0046907 32 0.055
Mouse
neuron apoptotic process GO:0051402 20 0.055
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.054
Mouse Worm
axis specification GO:0009798 43 0.054
zymogen activation GO:0031638 3 0.054
embryonic skeletal system morphogenesis GO:0048704 93 0.054
regulation of reproductive process GO:2000241 4 0.052
homeostasis of number of cells GO:0048872 62 0.052
Mouse
positive regulation of biological process GO:0048518 253 0.052
Human Zebrafish Mouse Worm
localization of cell GO:0051674 244 0.051
Mouse
modulation by virus of host morphology or physiology GO:0019048 1 0.051
negative regulation of leukocyte differentiation GO:1902106 1 0.051
cellular response to nutrient levels GO:0031669 2 0.051
Mouse
regulation of neurogenesis GO:0050767 87 0.050
Mouse
ameboidal type cell migration GO:0001667 143 0.050
regeneration GO:0031099 91 0.049
Mouse
myotube differentiation GO:0014902 45 0.048
Mouse
wound healing GO:0042060 90 0.048
connective tissue development GO:0061448 99 0.047
blood vessel morphogenesis GO:0048514 216 0.047
maintenance of location GO:0051235 4 0.047
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.046
Human
embryonic heart tube development GO:0035050 133 0.046
macroautophagy GO:0016236 1 0.046
cellular component assembly GO:0022607 170 0.045
Mouse
regulation of neuron apoptotic process GO:0043523 17 0.045
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.045
Zebrafish Mouse Worm
aromatic compound biosynthetic process GO:0019438 217 0.044
regulation of protein metabolic process GO:0051246 56 0.044
gliogenesis GO:0042063 45 0.043
Rat
regulation of apoptotic process GO:0042981 98 0.043
positive regulation of epithelial cell migration GO:0010634 2 0.043
transport GO:0006810 220 0.043
Human Mouse
cellular calcium ion homeostasis GO:0006874 13 0.043
Mouse
regulation of catalytic activity GO:0050790 55 0.043
endosome organization GO:0007032 2 0.042
convergent extension GO:0060026 118 0.042
cell cell signaling GO:0007267 52 0.042
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.042
positive regulation of endothelial cell proliferation GO:0001938 1 0.042
establishment of protein localization to organelle GO:0072594 4 0.042
axon extension GO:0048675 45 0.042
nucleoside phosphate metabolic process GO:0006753 28 0.042
Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.041
dorsal ventral pattern formation GO:0009953 125 0.040
regulation of purine nucleotide catabolic process GO:0033121 2 0.040
Worm
synaptic transmission GO:0007268 35 0.040
protein localization to nucleus GO:0034504 3 0.040
cellular component disassembly GO:0022411 1 0.040
skeletal system development GO:0001501 181 0.040
response to nutrient GO:0007584 3 0.039
Rat
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.039
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
Human Mouse
single organism metabolic process GO:0044710 217 0.039
Mouse Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.038
Worm
cytokinesis GO:0000910 3 0.038
heart development GO:0007507 313 0.038
positive regulation of myeloid cell differentiation GO:0045639 2 0.038
negative regulation of reproductive process GO:2000242 3 0.038
divalent inorganic cation transport GO:0072511 21 0.038
Human Mouse
positive regulation of molecular function GO:0044093 33 0.038
Zebrafish Mouse Worm
nuclear import GO:0051170 3 0.038
transmembrane transport GO:0055085 120 0.038
Human
immune response GO:0006955 28 0.038
Human
sequestering of metal ion GO:0051238 3 0.037
nucleobase containing small molecule metabolic process GO:0055086 32 0.037
Worm
positive regulation of response to stimulus GO:0048584 80 0.037
Human
response to hormone GO:0009725 48 0.037
Mouse Rat
hindbrain development GO:0030902 91 0.036
Mouse
ossification GO:0001503 23 0.036
Mouse
regulation of carbohydrate metabolic process GO:0006109 4 0.036
regulation of phosphate metabolic process GO:0019220 43 0.036
Mouse Worm
cellular protein metabolic process GO:0044267 129 0.036
positive regulation of hydrolase activity GO:0051345 13 0.036
Zebrafish Worm
negative regulation of metabolic process GO:0009892 86 0.036
cellular response to stress GO:0033554 62 0.036
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.035
Mouse
spinal cord anterior posterior patterning GO:0021512 1 0.035
angiogenesis GO:0001525 158 0.035
organelle fusion GO:0048284 3 0.035
Worm
positive regulation of neuron apoptotic process GO:0043525 1 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
intrinsic apoptotic signaling pathway GO:0097193 20 0.034
Human Zebrafish Mouse
response to alcohol GO:0097305 14 0.034
Rat
regulation of membrane potential GO:0042391 23 0.034
Mouse
release of sequestered calcium ion into cytosol GO:0051209 3 0.034
calcium ion homeostasis GO:0055074 19 0.034
Mouse
regulation of biosynthetic process GO:0009889 250 0.033
Mouse
cellular response to hypoxia GO:0071456 1 0.033
Mouse
tissue remodeling GO:0048771 4 0.033
cellular divalent inorganic cation homeostasis GO:0072503 13 0.033
Mouse
oligodendrocyte differentiation GO:0048709 23 0.033
Rat
single organism membrane organization GO:0044802 20 0.033
Mouse Worm
cellular biosynthetic process GO:0044249 286 0.033
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
macromolecule modification GO:0043412 111 0.032
Human Mouse
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.032
Human Zebrafish
protein import into nucleus GO:0006606 3 0.032
positive regulation of map kinase activity GO:0043406 3 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
positive regulation of cell communication GO:0010647 56 0.032
nitrogen compound metabolic process GO:0006807 319 0.032
Worm
regulation of sequestering of calcium ion GO:0051282 4 0.032
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
liver development GO:0001889 96 0.032
striated muscle tissue development GO:0014706 110 0.031
Mouse
heart looping GO:0001947 94 0.031
b cell differentiation GO:0030183 1 0.031
Mouse
camera type eye development GO:0043010 222 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
protein import GO:0017038 3 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
Mouse Worm
response to decreased oxygen levels GO:0036293 25 0.031
Mouse Rat
nephron epithelium morphogenesis GO:0072088 1 0.030
Mouse
regulation of localization GO:0032879 104 0.030
Human Mouse
protein modification process GO:0036211 100 0.030
Human Mouse
negative regulation of developmental process GO:0051093 65 0.030
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.030
Mouse Worm
digestive tract mesoderm development GO:0007502 1 0.030
protein targeting to nucleus GO:0044744 3 0.029
leukocyte proliferation GO:0070661 1 0.029
Human
positive regulation of signal transduction GO:0009967 56 0.029
neuron neuron synaptic transmission GO:0007270 1 0.029
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.029
muscle cell development GO:0055001 115 0.029
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.029
t cell differentiation GO:0030217 6 0.029
Mouse
negative regulation of response to stimulus GO:0048585 104 0.028
Human Zebrafish Mouse
carboxylic acid metabolic process GO:0019752 22 0.028
regulation of stem cell proliferation GO:0072091 2 0.028
regulation of molecular function GO:0065009 70 0.028
regulation of cell activation GO:0050865 1 0.028
Human
aging GO:0007568 2 0.028
Mouse Rat
regulation of cell division GO:0051302 12 0.028
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.028
Zebrafish Mouse
regulation of cell cycle GO:0051726 52 0.028
Zebrafish Mouse
regulation of endothelial cell proliferation GO:0001936 1 0.028
regulation of synapse assembly GO:0051963 3 0.027
camera type eye morphogenesis GO:0048593 108 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
modification of morphology or physiology of other organism GO:0035821 4 0.027
cellular component biogenesis GO:0044085 178 0.027
Mouse
positive regulation of dna metabolic process GO:0051054 1 0.027
cellular metal ion homeostasis GO:0006875 16 0.027
Mouse
kidney development GO:0001822 92 0.027
Mouse
muscle tissue development GO:0060537 110 0.026
Mouse
determination of heart left right asymmetry GO:0061371 117 0.026
organophosphate metabolic process GO:0019637 37 0.026
Worm
negative regulation of cytoplasmic transport GO:1903650 2 0.026
Mouse
morphogenesis of an epithelium GO:0002009 333 0.026
Mouse
catabolic process GO:0009056 32 0.026
Worm
positive regulation of cellular protein metabolic process GO:0032270 22 0.026
Zebrafish Mouse
microtubule polymerization or depolymerization GO:0031109 3 0.026
mitotic cell cycle process GO:1903047 48 0.026
Zebrafish Mouse
negative regulation of cell proliferation GO:0008285 8 0.026
Mouse
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.026
regulation of nervous system development GO:0051960 90 0.026
Mouse
heart morphogenesis GO:0003007 156 0.026
regulation of proteolysis GO:0030162 24 0.025
developmental maturation GO:0021700 34 0.025
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
Mouse
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
Mouse
negative regulation of protein complex assembly GO:0031333 1 0.025
embryonic skeletal system development GO:0048706 97 0.025
positive regulation of transport GO:0051050 2 0.025
cardiac atrium morphogenesis GO:0003209 2 0.025
protein acetylation GO:0006473 2 0.025
blood vessel development GO:0001568 246 0.025
calcium ion import GO:0070509 4 0.025
oxoacid metabolic process GO:0043436 31 0.025
thyroid gland development GO:0030878 12 0.025
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
Worm
tissue migration GO:0090130 37 0.025
positive regulation of metabolic process GO:0009893 108 0.025
Zebrafish Mouse Worm
dna templated transcription initiation GO:0006352 1 0.025
regulation of homeostatic process GO:0032844 9 0.024
Human Mouse
neuron projection development GO:0031175 180 0.024
Mouse
epithelium migration GO:0090132 25 0.024
glial cell differentiation GO:0010001 42 0.024
Rat
developmental programmed cell death GO:0010623 4 0.024
Mouse
t cell differentiation in thymus GO:0033077 6 0.024
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.024
hepatocyte proliferation GO:0072574 2 0.024
regulation of protein transport GO:0051223 3 0.024
protein processing GO:0016485 12 0.024
diencephalon development GO:0021536 58 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.023
response to nutrient levels GO:0031667 10 0.023
Mouse Rat
heterocycle catabolic process GO:0046700 15 0.023
Worm
regulation of cell size GO:0008361 29 0.023
regulation of mitochondrion organization GO:0010821 1 0.023
Worm
chemical homeostasis GO:0048878 49 0.023
Human Mouse
lateral line system development GO:0048925 76 0.023
renal system development GO:0072001 94 0.022
Mouse
positive regulation of neuron death GO:1901216 1 0.022
chemotaxis GO:0006935 104 0.022
cellular amide metabolic process GO:0043603 4 0.022
negative regulation of mitotic cell cycle GO:0045930 11 0.022
Zebrafish Mouse
nephron tubule morphogenesis GO:0072078 1 0.022
Mouse
mononuclear cell proliferation GO:0032943 1 0.022
Human
negative regulation of gene expression GO:0010629 65 0.022
central nervous system neuron differentiation GO:0021953 74 0.022
regulation of gtpase activity GO:0043087 2 0.022
Worm
canonical wnt signaling pathway GO:0060070 48 0.022
regulation of organ morphogenesis GO:2000027 35 0.022
Mouse
regulation of transport GO:0051049 45 0.022
Human Mouse
protein acylation GO:0043543 3 0.022
regulation of chronic inflammatory response GO:0002676 1 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
Mouse
negative regulation of protein transport GO:0051224 3 0.021
fluid transport GO:0042044 17 0.021
positive regulation of stem cell proliferation GO:2000648 1 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.021
Mouse Worm
hepaticobiliary system development GO:0061008 98 0.021
leukocyte homeostasis GO:0001776 2 0.021
Mouse
tube morphogenesis GO:0035239 349 0.021
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
organic substance catabolic process GO:1901575 28 0.021
Worm
nucleocytoplasmic transport GO:0006913 4 0.021
b cell activation GO:0042113 2 0.021
Human Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.021
Human
negative regulation of molecular function GO:0044092 23 0.021
chromosome organization GO:0051276 31 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
wnt signaling pathway GO:0016055 80 0.020
sodium ion transmembrane transport GO:0035725 21 0.020
regulation of production of molecular mediator of immune response GO:0002700 1 0.020
vasculature development GO:0001944 278 0.020
peptide transport GO:0015833 1 0.020
membrane hyperpolarization GO:0060081 1 0.020
protein depolymerization GO:0051261 1 0.020
regulation of mrna processing GO:0050684 3 0.020
internal peptidyl lysine acetylation GO:0018393 2 0.020
cardiac atrium development GO:0003230 4 0.019
positive regulation of stress activated mapk cascade GO:0032874 3 0.019
organic acid metabolic process GO:0006082 31 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
establishment of localization in cell GO:0051649 77 0.019
Mouse
biomineral tissue development GO:0031214 13 0.019
regulation of vitamin metabolic process GO:0030656 6 0.019
negative regulation of myeloid cell differentiation GO:0045638 1 0.019
striated muscle cell differentiation GO:0051146 129 0.019
Mouse
positive regulation of translation GO:0045727 1 0.019
muscle structure development GO:0061061 196 0.019
Mouse
positive regulation of cell adhesion GO:0045785 1 0.019
fin regeneration GO:0031101 51 0.019
interaction with host GO:0051701 4 0.019
cell matrix adhesion GO:0007160 4 0.019
Mouse
cell proliferation in forebrain GO:0021846 3 0.019
alpha amino acid metabolic process GO:1901605 3 0.019
regulation of mitosis GO:0007088 9 0.019
Zebrafish
mitotic cell cycle GO:0000278 64 0.019
Zebrafish Mouse
regulation of multicellular organism growth GO:0040014 4 0.019
Mouse
habenula development GO:0021986 9 0.019

bcl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.190
disease of cellular proliferation DOID:14566 0 0.190
organ system cancer DOID:0050686 0 0.089
gastrointestinal system cancer DOID:3119 0 0.048
disease of anatomical entity DOID:7 0 0.041