Danio rerio

0 known processes

mthfd2l

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

(Aliases: zgc:63479,wu:fi14c12)

mthfd2l biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular modified amino acid metabolic process GO:0006575 3 0.123
single organism localization GO:1902578 225 0.118
establishment of localization GO:0051234 244 0.096
deoxyribose phosphate metabolic process GO:0019692 1 0.092
embryonic organ morphogenesis GO:0048562 274 0.087
larval development GO:0002164 2 0.070
pyrimidine containing compound metabolic process GO:0072527 3 0.068
single organism transport GO:0044765 206 0.065
ion transport GO:0006811 114 0.065
maintenance of location GO:0051235 4 0.053
multicellular organism growth GO:0035264 4 0.048
striated muscle cell development GO:0055002 108 0.045
aging GO:0007568 2 0.042
cellular amino acid biosynthetic process GO:0008652 2 0.041
regulation of multicellular organism growth GO:0040014 4 0.040
adult behavior GO:0030534 2 0.039
tube morphogenesis GO:0035239 349 0.039
carboxylic acid metabolic process GO:0019752 22 0.035
morphogenesis of an epithelium GO:0002009 333 0.035
small molecule metabolic process GO:0044281 77 0.033
protein localization to nucleus GO:0034504 3 0.033
regionalization GO:0003002 274 0.033
organic acid metabolic process GO:0006082 31 0.031
embryonic organ development GO:0048568 381 0.029
lipid storage GO:0019915 1 0.027
oxoacid metabolic process GO:0043436 31 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
cell part morphogenesis GO:0032990 246 0.026
regulation of reproductive process GO:2000241 4 0.026
cellular localization GO:0051641 97 0.026
striated muscle tissue development GO:0014706 110 0.026
epithelial tube morphogenesis GO:0060562 148 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
water soluble vitamin metabolic process GO:0006767 1 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
stem cell proliferation GO:0072089 4 0.023
cellular amine metabolic process GO:0044106 2 0.023
transport GO:0006810 220 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
amine metabolic process GO:0009308 2 0.022
rna localization GO:0006403 4 0.022
positive regulation of catabolic process GO:0009896 4 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
regulation of dendrite development GO:0050773 3 0.022
regulation of synapse assembly GO:0051963 3 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
amino acid transport GO:0006865 2 0.022
mitochondrion organization GO:0007005 4 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
regulation of synapse organization GO:0050807 3 0.021
organic substance biosynthetic process GO:1901576 289 0.021
adherens junction organization GO:0034332 4 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
specification of symmetry GO:0009799 204 0.021
regulation of developmental process GO:0050793 247 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
regulation of biological quality GO:0065008 263 0.019
heart looping GO:0001947 94 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
digestive tract morphogenesis GO:0048546 231 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
protein targeting to nucleus GO:0044744 3 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
single organism nuclear import GO:1902593 3 0.018
heart development GO:0007507 313 0.018
negative regulation of kinase activity GO:0033673 4 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
heart morphogenesis GO:0003007 156 0.018
striated muscle cell differentiation GO:0051146 129 0.018
negative regulation of reproductive process GO:2000242 3 0.017
nuclear import GO:0051170 3 0.017
cellular response to nutrient levels GO:0031669 2 0.017
developmental growth GO:0048589 166 0.017
muscle structure development GO:0061061 196 0.017
protein import into nucleus GO:0006606 3 0.017
morphogenesis of embryonic epithelium GO:0016331 30 0.017
sensory organ development GO:0007423 393 0.017
cellular amide metabolic process GO:0043603 4 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
determination of bilateral symmetry GO:0009855 204 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
response to chemical GO:0042221 320 0.016
cellular protein catabolic process GO:0044257 4 0.016
digestive tract development GO:0048565 265 0.016
biosynthetic process GO:0009058 294 0.016
protein import GO:0017038 3 0.016
regulation of metal ion transport GO:0010959 4 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
tube closure GO:0060606 1 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
locomotion GO:0040011 313 0.016
negative regulation of biological process GO:0048519 304 0.015
positive regulation of biological process GO:0048518 253 0.015
nucleobase containing compound transport GO:0015931 2 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
gtp catabolic process GO:0006184 2 0.015
phagocytosis GO:0006909 3 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
golgi vesicle transport GO:0048193 3 0.015
cellular response to external stimulus GO:0071496 2 0.015
negative regulation of intracellular transport GO:0032387 3 0.014
muscle cell development GO:0055001 115 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
single organism biosynthetic process GO:0044711 71 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
endosomal transport GO:0016197 2 0.014
convergent extension GO:0060026 118 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
synaptic target recognition GO:0008039 1 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
muscle organ development GO:0007517 101 0.014
exocytosis GO:0006887 1 0.014
nuclear transport GO:0051169 4 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
embryonic heart tube development GO:0035050 133 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of hormone secretion GO:0046883 2 0.013
dicarboxylic acid metabolic process GO:0043648 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
response to xenobiotic stimulus GO:0009410 45 0.013
compound eye development GO:0048749 2 0.013
determination of left right symmetry GO:0007368 179 0.013
digestive system development GO:0055123 289 0.013
eye development GO:0001654 277 0.013
regulation of protein transport GO:0051223 3 0.013
brain development GO:0007420 293 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
regulation of cell shape GO:0008360 1 0.013
cellular component movement GO:0006928 335 0.012
regulation of cytokine production GO:0001817 3 0.012
pharyngeal muscle development GO:0043282 4 0.012
system process GO:0003008 185 0.012
cellular response to starvation GO:0009267 1 0.012
regulation of binding GO:0051098 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
retina development in camera type eye GO:0060041 146 0.012
centrosome cycle GO:0007098 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cilium organization GO:0044782 71 0.012
growth GO:0040007 174 0.012
apoptotic process involved in development GO:1902742 2 0.012
somatic stem cell maintenance GO:0035019 1 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
neuroblast proliferation GO:0007405 2 0.012
signal transduction GO:0007165 455 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
membrane fusion GO:0061025 2 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
cell projection organization GO:0030030 284 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
establishment of rna localization GO:0051236 3 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of calcium ion transport GO:0051924 2 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
rna transport GO:0050658 2 0.011
b cell activation GO:0042113 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of nervous system development GO:0051960 90 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
skeletal muscle fiber development GO:0048741 35 0.011
camera type eye development GO:0043010 222 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
membrane invagination GO:0010324 1 0.011
gastrulation GO:0007369 208 0.011
regulation of protein catabolic process GO:0042176 1 0.011
chordate embryonic development GO:0043009 271 0.011
primary neural tube formation GO:0014020 1 0.011
regulation of protein targeting GO:1903533 2 0.011
tissue remodeling GO:0048771 4 0.011
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
rna metabolic process GO:0016070 219 0.011
peptide metabolic process GO:0006518 1 0.011
localization of cell GO:0051674 244 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
cellular biosynthetic process GO:0044249 286 0.011
secondary metabolic process GO:0019748 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cation transport GO:0006812 81 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
neurological system process GO:0050877 62 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of exocytosis GO:0017157 1 0.011
regulation of cell differentiation GO:0045595 142 0.010
response to carbohydrate GO:0009743 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
neuron projection morphogenesis GO:0048812 161 0.010
protein metabolic process GO:0019538 183 0.010
cell projection morphogenesis GO:0048858 244 0.010
cellular component disassembly GO:0022411 1 0.010
cell killing GO:0001906 2 0.010
positive regulation of secretion GO:0051047 1 0.010
centrosome organization GO:0051297 1 0.010
regulation of oocyte development GO:0060281 3 0.010
regulation of response to stimulus GO:0048583 269 0.010
ribosomal small subunit biogenesis GO:0042274 2 0.010

mthfd2l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.014
disease of cellular proliferation DOID:14566 0 0.010