Danio rerio

0 known processes

si:dkey-261l7.3

si:dkey-261l7.3

(Aliases: im:7147010,brwd1)

si:dkey-261l7.3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.085
aging GO:0007568 2 0.048
positive regulation of transport GO:0051050 2 0.045
maintenance of location GO:0051235 4 0.043
multicellular organism growth GO:0035264 4 0.041
lipid storage GO:0019915 1 0.035
positive regulation of cell cycle GO:0045787 3 0.035
regulation of multicellular organism growth GO:0040014 4 0.034
regulation of protein transport GO:0051223 3 0.034
cellular protein catabolic process GO:0044257 4 0.033
nuclear transport GO:0051169 4 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
establishment of protein localization to organelle GO:0072594 4 0.031
regulation of cytokine production GO:0001817 3 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
phagocytosis GO:0006909 3 0.031
amine metabolic process GO:0009308 2 0.030
stem cell maintenance GO:0019827 4 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
meiotic nuclear division GO:0007126 4 0.029
positive regulation of catabolic process GO:0009896 4 0.028
regulation of mrna processing GO:0050684 3 0.027
cytokinesis GO:0000910 3 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
signal transduction GO:0007165 455 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
endosomal transport GO:0016197 2 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
modification dependent protein catabolic process GO:0019941 3 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
regulation of binding GO:0051098 3 0.026
response to chemical GO:0042221 320 0.026
cellular amine metabolic process GO:0044106 2 0.026
nucleocytoplasmic transport GO:0006913 4 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
regulation of protein complex assembly GO:0043254 3 0.025
response to drug GO:0042493 3 0.025
cellular response to external stimulus GO:0071496 2 0.025
organelle organization GO:0006996 227 0.025
cellular ketone metabolic process GO:0042180 11 0.024
positive regulation of cell adhesion GO:0045785 1 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
gtp catabolic process GO:0006184 2 0.024
nucleic acid templated transcription GO:0097659 181 0.023
autophagy GO:0006914 4 0.023
protein import GO:0017038 3 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
heterocycle metabolic process GO:0046483 290 0.023
golgi vesicle transport GO:0048193 3 0.023
cellular biosynthetic process GO:0044249 286 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
negative regulation of biological process GO:0048519 304 0.023
protein localization to nucleus GO:0034504 3 0.023
gtp metabolic process GO:0046039 4 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
mitochondrion organization GO:0007005 4 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
response to topologically incorrect protein GO:0035966 2 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
stem cell proliferation GO:0072089 4 0.022
regulation of response to stimulus GO:0048583 269 0.022
protein acetylation GO:0006473 2 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
rna metabolic process GO:0016070 219 0.021
biosynthetic process GO:0009058 294 0.021
regulation of cell shape GO:0008360 1 0.021
membrane fusion GO:0061025 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
protein localization to plasma membrane GO:0072659 1 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
regulation of cell activation GO:0050865 1 0.021
response to carbohydrate GO:0009743 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
cell projection morphogenesis GO:0048858 244 0.021
gene expression GO:0010467 252 0.021
neuroblast proliferation GO:0007405 2 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
response to stress GO:0006950 263 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
central nervous system development GO:0007417 387 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
regionalization GO:0003002 274 0.021
organic substance biosynthetic process GO:1901576 289 0.021
positive regulation of cytokine production GO:0001819 2 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
nucleic acid metabolic process GO:0090304 244 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
cellular component disassembly GO:0022411 1 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
cellular component movement GO:0006928 335 0.020
nuclear import GO:0051170 3 0.020
regulation of inflammatory response GO:0050727 2 0.020
stem cell division GO:0017145 1 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
cortical cytoskeleton organization GO:0030865 1 0.020
regulation of protein catabolic process GO:0042176 1 0.020
protein secretion GO:0009306 1 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
regulation of reproductive process GO:2000241 4 0.020
forebrain cell migration GO:0021885 1 0.020
organelle fusion GO:0048284 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
small molecule metabolic process GO:0044281 77 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of signal transduction GO:0009966 225 0.019
transcription dna templated GO:0006351 181 0.019
organic acid metabolic process GO:0006082 31 0.019
positive regulation of secretion GO:0051047 1 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
protein import into nucleus GO:0006606 3 0.019
cognition GO:0050890 1 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
cellular response to starvation GO:0009267 1 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
regulation of cell communication GO:0010646 232 0.019
aromatic compound biosynthetic process GO:0019438 217 0.018
regulation of developmental process GO:0050793 247 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
tissue remodeling GO:0048771 4 0.018
adult behavior GO:0030534 2 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
single organism membrane fusion GO:0044801 2 0.018
protein targeting to nucleus GO:0044744 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
sensory organ development GO:0007423 393 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
protein acylation GO:0043543 3 0.018
neuron differentiation GO:0030182 353 0.018
macroautophagy GO:0016236 1 0.018
microtubule organizing center organization GO:0031023 1 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
regulation of biological quality GO:0065008 263 0.018
regulation of protein targeting GO:1903533 2 0.018
tube morphogenesis GO:0035239 349 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
oxoacid metabolic process GO:0043436 31 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
single organism nuclear import GO:1902593 3 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
regulation of synapse assembly GO:0051963 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
phagocytosis engulfment GO:0006911 1 0.018
cell morphogenesis GO:0000902 289 0.018
locomotion GO:0040011 313 0.018
embryonic organ development GO:0048568 381 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
cell substrate adhesion GO:0031589 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
positive regulation of biological process GO:0048518 253 0.017
exocytosis GO:0006887 1 0.017
regulation of signaling GO:0023051 235 0.017
head development GO:0060322 303 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
single organism organelle organization GO:1902589 199 0.017
regulation of synapse organization GO:0050807 3 0.017
cell part morphogenesis GO:0032990 246 0.017
female sex differentiation GO:0046660 4 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
regulation of gene expression GO:0010468 265 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
cortical actin cytoskeleton organization GO:0030866 1 0.017
protein dephosphorylation GO:0006470 3 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
protein polymerization GO:0051258 4 0.017
alternative mrna splicing via spliceosome GO:0000380 1 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
lamellipodium assembly GO:0030032 1 0.017
regulation of transcription dna templated GO:0006355 213 0.017
regulation of biosynthetic process GO:0009889 250 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
cell motility GO:0048870 244 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
positive regulation of cell activation GO:0050867 1 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
rna biosynthetic process GO:0032774 181 0.016
leukocyte proliferation GO:0070661 1 0.016
establishment of localization GO:0051234 244 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
cell projection organization GO:0030030 284 0.016
immune system process GO:0002376 241 0.016
protein complex disassembly GO:0043241 1 0.016
spermatid development GO:0007286 2 0.016
single organism localization GO:1902578 225 0.016
neuron development GO:0048666 262 0.016
negative regulation of cellular process GO:0048523 283 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
response to external stimulus GO:0009605 264 0.015
peptidyl serine modification GO:0018209 2 0.015
rna localization GO:0006403 4 0.015
positive regulation of notch signaling pathway GO:0045747 3 0.015
eye development GO:0001654 277 0.015
locomotor rhythm GO:0045475 3 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of rna metabolic process GO:0051252 224 0.015
macromolecular complex disassembly GO:0032984 1 0.015
response to organic substance GO:0010033 153 0.015
membrane invagination GO:0010324 1 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
cell matrix adhesion GO:0007160 4 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
regulation of circadian rhythm GO:0042752 4 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
response to nutrient GO:0007584 3 0.015
somatic stem cell maintenance GO:0035019 1 0.015
single organism transport GO:0044765 206 0.015
synaptic vesicle transport GO:0048489 1 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
synaptic vesicle localization GO:0097479 1 0.015
female gonad development GO:0008585 4 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of jak stat cascade GO:0046425 3 0.015
response to monosaccharide GO:0034284 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
double strand break repair GO:0006302 3 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
protein polyubiquitination GO:0000209 4 0.014
single fertilization GO:0007338 3 0.014
protein metabolic process GO:0019538 183 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
cell migration GO:0016477 237 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
cellular protein metabolic process GO:0044267 129 0.014
positive regulation of immune effector process GO:0002699 3 0.014
mononuclear cell proliferation GO:0032943 1 0.014
cellular component morphogenesis GO:0032989 336 0.014
chemosensory behavior GO:0007635 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
heart development GO:0007507 313 0.014
negative regulation of kinase activity GO:0033673 4 0.014
secondary metabolic process GO:0019748 3 0.014
germ line stem cell maintenance GO:0030718 2 0.014
wnt signaling pathway GO:0016055 80 0.014
centrosome organization GO:0051297 1 0.014
negative regulation of catabolic process GO:0009895 3 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of gtpase activity GO:0043087 2 0.014
system process GO:0003008 185 0.014
glucose homeostasis GO:0042593 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
organism emergence from protective structure GO:0071684 4 0.014
response to uv GO:0009411 3 0.014
negative regulation of protein transport GO:0051224 3 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
liver development GO:0001889 96 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
generation of neurons GO:0048699 385 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
cellular protein modification process GO:0006464 100 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
cellular response to radiation GO:0071478 4 0.013
gland development GO:0048732 143 0.013
spermatid differentiation GO:0048515 2 0.013
localization of cell GO:0051674 244 0.013
atp catabolic process GO:0006200 4 0.013
transport GO:0006810 220 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
lamellipodium organization GO:0097581 1 0.013
vasculature development GO:0001944 278 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
digestive system development GO:0055123 289 0.013
blood vessel development GO:0001568 246 0.013
regulation of organelle assembly GO:1902115 4 0.013
specification of symmetry GO:0009799 204 0.013
segmentation GO:0035282 97 0.013
cytokinetic process GO:0032506 2 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
regulation of autophagy GO:0010506 3 0.013
response to glucose GO:0009749 3 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
alcohol biosynthetic process GO:0046165 2 0.013
cellular amide metabolic process GO:0043603 4 0.013
growth GO:0040007 174 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
cellular respiration GO:0045333 3 0.013
response to hexose GO:0009746 3 0.013
cellular response to organic substance GO:0071310 105 0.013
somatic muscle development GO:0007525 4 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.012
cell death GO:0008219 121 0.012
homeostatic process GO:0042592 142 0.012
regulation of programmed cell death GO:0043067 101 0.012
cellular component biogenesis GO:0044085 178 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
regulation of receptor mediated endocytosis GO:0048259 4 0.012
response to alkaloid GO:0043279 2 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
brain development GO:0007420 293 0.012
b cell activation GO:0042113 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of primary metabolic process GO:0080090 311 0.012
skeletal system development GO:0001501 181 0.012
cellular response to light stimulus GO:0071482 4 0.012
regulation of metal ion transport GO:0010959 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
response to wounding GO:0009611 116 0.012
regulation of protein polymerization GO:0032271 2 0.012
developmental growth GO:0048589 166 0.012
primary neural tube formation GO:0014020 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
macromolecule modification GO:0043412 111 0.012
blood vessel morphogenesis GO:0048514 216 0.012
axon development GO:0061564 166 0.012
regulation of localization GO:0032879 104 0.012
protein targeting to membrane GO:0006612 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
outflow tract morphogenesis GO:0003151 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
regulation of apoptotic process GO:0042981 98 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
response to abiotic stimulus GO:0009628 122 0.011
apoptotic process GO:0006915 116 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
muscle structure development GO:0061061 196 0.011
hepaticobiliary system development GO:0061008 98 0.011
cell substrate junction assembly GO:0007044 2 0.011
nucleic acid transport GO:0050657 2 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
nuclear export GO:0051168 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of translation GO:0045727 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
sequestering of metal ion GO:0051238 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
camera type eye development GO:0043010 222 0.011
mitotic cytokinesis GO:0000281 3 0.011
regulation of protein binding GO:0043393 3 0.011
meiotic chromosome segregation GO:0045132 3 0.011
response to unfolded protein GO:0006986 2 0.011
protein homooligomerization GO:0051260 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
cilium morphogenesis GO:0060271 85 0.011
compound eye development GO:0048749 2 0.011
negative regulation of cytokine production GO:0001818 1 0.011
axonogenesis GO:0007409 152 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
peptide transport GO:0015833 1 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
centrosome cycle GO:0007098 1 0.011
regulation of cell death GO:0010941 103 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
post embryonic organ development GO:0048569 4 0.011
lipid homeostasis GO:0055088 3 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
centrosome duplication GO:0051298 1 0.011
tube closure GO:0060606 1 0.011
immune system development GO:0002520 191 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
angiogenesis GO:0001525 158 0.010
determination of left right symmetry GO:0007368 179 0.010
positive regulation of cell division GO:0051781 2 0.010
regulation of blood pressure GO:0008217 1 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.010
melanin metabolic process GO:0006582 2 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
regulation of growth rate GO:0040009 1 0.010
regulation of cell development GO:0060284 100 0.010
death GO:0016265 121 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
regulation of cell differentiation GO:0045595 142 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
chordate embryonic development GO:0043009 271 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
sensory organ morphogenesis GO:0090596 200 0.010
vacuolar transport GO:0007034 2 0.010
protein modification process GO:0036211 100 0.010
hormone secretion GO:0046879 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
regulation of cell projection assembly GO:0060491 4 0.010
cytoplasm organization GO:0007028 4 0.010
digestive tract development GO:0048565 265 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
hormone transport GO:0009914 2 0.010
regulation of nervous system development GO:0051960 90 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010

si:dkey-261l7.3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.022
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011