Danio rerio

0 known processes

cldnh

claudin h

(Aliases: fc56d05,wu:fc56d05)

cldnh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of sodium ion transport GO:0002028 2 0.977
Zebrafish
sensory system development GO:0048880 76 0.974
Zebrafish
lateral line system development GO:0048925 76 0.921
Zebrafish
regulation of metal ion transport GO:0010959 4 0.852
Zebrafish
establishment of endothelial barrier GO:0061028 3 0.816
Zebrafish
ion transport GO:0006811 114 0.774
Zebrafish
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.749
Zebrafish
tube morphogenesis GO:0035239 349 0.746
Zebrafish
cellular sodium ion homeostasis GO:0006883 1 0.681
monovalent inorganic cation transport GO:0015672 42 0.654
Zebrafish
metal ion transport GO:0030001 58 0.634
Zebrafish
neuromast development GO:0048884 46 0.608
Zebrafish
lateral line development GO:0048882 66 0.567
Zebrafish
epiboly GO:0090504 41 0.528
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.508
Zebrafish
sodium ion transport GO:0006814 24 0.471
Zebrafish
ear development GO:0043583 127 0.460
digestive tract development GO:0048565 265 0.457
Zebrafish
inner ear morphogenesis GO:0042472 63 0.411
single organism transport GO:0044765 206 0.387
Zebrafish
endothelial cell development GO:0001885 12 0.380
Zebrafish
transport GO:0006810 220 0.346
Zebrafish
negative regulation of heart contraction GO:0045822 2 0.329
sensory organ development GO:0007423 393 0.316
Zebrafish
homeostatic process GO:0042592 142 0.306
brain development GO:0007420 293 0.299
monovalent inorganic cation homeostasis GO:0055067 9 0.285
response to chemical GO:0042221 320 0.278
aging GO:0007568 2 0.272
sodium ion homeostasis GO:0055078 3 0.267
cation transport GO:0006812 81 0.258
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.241
response to abiotic stimulus GO:0009628 122 0.237
regulation of system process GO:0044057 40 0.231
regulation of primary metabolic process GO:0080090 311 0.226
response to drug GO:0042493 3 0.224
epithelial cell differentiation GO:0030855 116 0.218
Zebrafish
morphogenesis of an epithelial sheet GO:0002011 49 0.215
Zebrafish
response to hormone GO:0009725 48 0.210
membrane repolarization GO:0086009 2 0.197
establishment of localization GO:0051234 244 0.195
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.191
regulation of heart contraction GO:0008016 32 0.188
larval development GO:0002164 2 0.186
regulation of biosynthetic process GO:0009889 250 0.183
heterocycle metabolic process GO:0046483 290 0.161
response to oxygen containing compound GO:1901700 55 0.158
head development GO:0060322 303 0.157
response to organic substance GO:0010033 153 0.156
inner ear development GO:0048839 126 0.155
cellular response to external stimulus GO:0071496 2 0.152
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.150
organic cyclic compound biosynthetic process GO:1901362 223 0.150
gastrulation with mouth forming second GO:0001702 44 0.146
Zebrafish
central nervous system development GO:0007417 387 0.144
regulation of striated muscle contraction GO:0006942 2 0.142
regulation of cellular biosynthetic process GO:0031326 245 0.136
regulation of ion transport GO:0043269 22 0.134
Zebrafish
gastrulation GO:0007369 208 0.129
Zebrafish
regulation of metabolic process GO:0019222 359 0.123
phosphate containing compound metabolic process GO:0006796 108 0.117
neurological system process GO:0050877 62 0.116
negative regulation of cellular process GO:0048523 283 0.109
response to stress GO:0006950 263 0.108
regulation of muscle contraction GO:0006937 3 0.105
single organism localization GO:1902578 225 0.105
Zebrafish
glucocorticoid metabolic process GO:0008211 2 0.102
nuclear transport GO:0051169 4 0.098
response to monosaccharide GO:0034284 3 0.097
regulation of nucleic acid templated transcription GO:1903506 213 0.096
aromatic compound biosynthetic process GO:0019438 217 0.091
regulation of localization GO:0032879 104 0.091
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.090
morphogenesis of an epithelium GO:0002009 333 0.089
Zebrafish
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.089
establishment of protein localization to organelle GO:0072594 4 0.089
small molecule metabolic process GO:0044281 77 0.087
regulation of rna metabolic process GO:0051252 224 0.084
nucleic acid metabolic process GO:0090304 244 0.083
digestive system development GO:0055123 289 0.082
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.082
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.081
response to steroid hormone GO:0048545 35 0.080
macromolecule biosynthetic process GO:0009059 227 0.079
eye development GO:0001654 277 0.079
cardiac muscle cell contraction GO:0086003 1 0.079
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.078
water homeostasis GO:0030104 4 0.077
response to hexose GO:0009746 3 0.076
mechanosensory lateral line system development GO:0048881 49 0.076
carboxylic acid metabolic process GO:0019752 22 0.074
s adenosylmethionine metabolic process GO:0046500 1 0.074
negative regulation of blood circulation GO:1903523 2 0.073
biosynthetic process GO:0009058 294 0.072
cellular response to chemical stimulus GO:0070887 157 0.071
response to glucocorticoid GO:0051384 1 0.071
protein localization to nucleus GO:0034504 3 0.070
protein import into nucleus GO:0006606 3 0.069
ear morphogenesis GO:0042471 64 0.067
mitochondrion organization GO:0007005 4 0.067
action potential GO:0001508 19 0.064
regulation of calcium ion transport GO:0051924 2 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.060
organic acid metabolic process GO:0006082 31 0.059
response to antibiotic GO:0046677 1 0.059
cellular nitrogen compound metabolic process GO:0034641 290 0.057
regulation of cardiac muscle contraction GO:0055117 2 0.056
cell migration GO:0016477 237 0.056
regulation of macromolecule biosynthetic process GO:0010556 225 0.054
cellular response to endogenous stimulus GO:0071495 68 0.053
system process GO:0003008 185 0.052
regulation of multicellular organism growth GO:0040014 4 0.052
cellular response to extracellular stimulus GO:0031668 2 0.051
organic substance biosynthetic process GO:1901576 289 0.050
one carbon compound transport GO:0019755 14 0.048
regulation of blood pressure GO:0008217 1 0.047
phagocytosis GO:0006909 3 0.047
positive regulation of blood circulation GO:1903524 2 0.046
single organism metabolic process GO:0044710 217 0.044
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 1 0.044
positive regulation of biological process GO:0048518 253 0.044
rna biosynthetic process GO:0032774 181 0.043
cellular biosynthetic process GO:0044249 286 0.043
positive regulation of phosphorus metabolic process GO:0010562 21 0.043
circadian rhythm GO:0007623 19 0.042
ion transmembrane transport GO:0034220 91 0.042
divalent inorganic cation homeostasis GO:0072507 22 0.042
heart process GO:0003015 71 0.042
sensory perception of mechanical stimulus GO:0050954 16 0.042
regionalization GO:0003002 274 0.041
otolith development GO:0048840 32 0.041
chemical homeostasis GO:0048878 49 0.040
endothelium development GO:0003158 25 0.040
Zebrafish
hormone biosynthetic process GO:0042446 3 0.038
hormone mediated signaling pathway GO:0009755 9 0.038
response to corticosteroid GO:0031960 1 0.037
female gonad development GO:0008585 4 0.036
regulation of protein import into nucleus GO:0042306 2 0.036
protein import GO:0017038 3 0.036
response to glucose GO:0009749 3 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
respiratory system development GO:0060541 5 0.036
cellular response to lipid GO:0071396 39 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.035
organic substance transport GO:0071702 58 0.035
signal transduction GO:0007165 455 0.035
cellular response to organic substance GO:0071310 105 0.035
positive regulation of catabolic process GO:0009896 4 0.034
cation transmembrane transport GO:0098655 65 0.034
regulation of cardiac muscle cell contraction GO:0086004 1 0.034
positive regulation of heart contraction GO:0045823 2 0.033
specification of organ axis polarity GO:0010084 2 0.033
carbohydrate derivative metabolic process GO:1901135 61 0.033
cell death GO:0008219 121 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
regulation of ion transmembrane transporter activity GO:0032412 2 0.033
nucleic acid templated transcription GO:0097659 181 0.032
single organism biosynthetic process GO:0044711 71 0.031
adult behavior GO:0030534 2 0.031
cellular component assembly involved in morphogenesis GO:0010927 107 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
regulation of blood circulation GO:1903522 32 0.031
regulation of developmental process GO:0050793 247 0.031
ph reduction GO:0045851 1 0.031
heart contraction GO:0060047 71 0.030
dorsal ventral pattern formation GO:0009953 125 0.030
response to hypoxia GO:0001666 25 0.030
sensory organ morphogenesis GO:0090596 200 0.030
cellular response to nutrient levels GO:0031669 2 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
renal absorption GO:0070293 1 0.029
negative regulation of biological process GO:0048519 304 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
apical junction assembly GO:0043297 1 0.029
sensory perception GO:0007600 39 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
negative regulation of multicellular organismal process GO:0051241 69 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.028
positive regulation of epithelial cell migration GO:0010634 2 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
ameboidal type cell migration GO:0001667 143 0.028
regulation of gene expression GO:0010468 265 0.028
cellular component biogenesis GO:0044085 178 0.028
carbon dioxide transport GO:0015670 3 0.027
negative regulation of neural precursor cell proliferation GO:2000178 1 0.027
polyol metabolic process GO:0019751 1 0.027
cell proliferation GO:0008283 80 0.027
cell morphogenesis GO:0000902 289 0.027
hormone transport GO:0009914 2 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
synaptic transmission GO:0007268 35 0.026
carbohydrate biosynthetic process GO:0016051 1 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.025
cell migration involved in heart formation GO:0060974 10 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
response to lipid GO:0033993 60 0.025
positive regulation of cellular metabolic process GO:0031325 94 0.025
single organism nuclear import GO:1902593 3 0.025
transcription from rna polymerase ii promoter GO:0006366 80 0.025
ion homeostasis GO:0050801 41 0.025
protein metabolic process GO:0019538 183 0.024
sequestering of metal ion GO:0051238 3 0.024
cellular component morphogenesis GO:0032989 336 0.024
protein targeting to nucleus GO:0044744 3 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.023
skeletal system development GO:0001501 181 0.023
purine nucleotide metabolic process GO:0006163 27 0.023
nuclear import GO:0051170 3 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
cellular response to oxygen levels GO:0071453 1 0.023
posterior lateral line system development GO:0048915 46 0.023
response to amino acid GO:0043200 2 0.023
lipid metabolic process GO:0006629 52 0.022
embryonic organ development GO:0048568 381 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
transmembrane transport GO:0055085 120 0.022
regulation of intracellular ph GO:0051453 1 0.022
response to salt stress GO:0009651 10 0.022
positive regulation of cellular process GO:0048522 201 0.022
photoreceptor cell fate commitment GO:0046552 1 0.022
gene expression GO:0010467 252 0.021
multicellular organism reproduction GO:0032504 35 0.021
cellular response to starvation GO:0009267 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.021
semicircular canal development GO:0060872 24 0.021
regulation of ph GO:0006885 3 0.021
amine metabolic process GO:0009308 2 0.021
chordate embryonic development GO:0043009 271 0.021
actin filament based process GO:0030029 64 0.020
female sex differentiation GO:0046660 4 0.020
regulation of biological quality GO:0065008 263 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
multicellular organism growth GO:0035264 4 0.020
regulation of programmed cell death GO:0043067 101 0.020
pigmentation GO:0043473 85 0.020
response to mechanical stimulus GO:0009612 24 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.019
lateral line ganglion development GO:0048890 2 0.019
response to endogenous stimulus GO:0009719 83 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
intestinal epithelial cell differentiation GO:0060575 3 0.019
response to carbohydrate GO:0009743 3 0.019
single organism behavior GO:0044708 24 0.019
regulation of establishment of protein localization GO:0070201 4 0.018
cellular response to hormone stimulus GO:0032870 39 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
rna metabolic process GO:0016070 219 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
atp catabolic process GO:0006200 4 0.017
regulation of transcription dna templated GO:0006355 213 0.017
positive regulation of rna metabolic process GO:0051254 59 0.017
cellular cation homeostasis GO:0030003 17 0.017
regulation of transport GO:0051049 45 0.017
Zebrafish
response to decreased oxygen levels GO:0036293 25 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
striated muscle tissue development GO:0014706 110 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
cranial ganglion development GO:0061550 3 0.017
behavior GO:0007610 74 0.016
cell projection organization GO:0030030 284 0.016
metal ion homeostasis GO:0055065 26 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of cell shape GO:0008360 1 0.016
muscle structure development GO:0061061 196 0.016
gamete generation GO:0007276 33 0.016
sensory perception of sound GO:0007605 9 0.016
negative regulation of metabolic process GO:0009892 86 0.016
peptidyl serine modification GO:0018209 2 0.016
anion transport GO:0006820 38 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
membrane hyperpolarization GO:0060081 1 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
regulation of cellular component movement GO:0051270 55 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
rhythmic process GO:0048511 21 0.015
circulatory system process GO:0003013 87 0.015
apoptotic process GO:0006915 116 0.015
positive regulation of metabolic process GO:0009893 108 0.015
muscle tissue development GO:0060537 110 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
transcription dna templated GO:0006351 181 0.015
endothelial cell differentiation GO:0045446 20 0.015
Zebrafish
regulation of transporter activity GO:0032409 2 0.015
alcohol biosynthetic process GO:0046165 2 0.015
organelle organization GO:0006996 227 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
regulation of actin filament based movement GO:1903115 1 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
somatic stem cell maintenance GO:0035019 1 0.014
cellular ketone metabolic process GO:0042180 11 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
neural nucleus development GO:0048857 15 0.014
cofactor metabolic process GO:0051186 15 0.013
cellular divalent inorganic cation homeostasis GO:0072503 13 0.013
connective tissue development GO:0061448 99 0.013
developmental pigmentation GO:0048066 48 0.013
blood vessel development GO:0001568 246 0.013
muscle system process GO:0003012 20 0.013
semicircular canal morphogenesis GO:0048752 18 0.013
response to oxygen levels GO:0070482 25 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of molecular function GO:0065009 70 0.013
neural tube development GO:0021915 62 0.013
ovarian follicle development GO:0001541 2 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
response to external stimulus GO:0009605 264 0.013
cell cell signaling GO:0007267 52 0.013
intracellular estrogen receptor signaling pathway GO:0030520 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
tissue homeostasis GO:0001894 25 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
immune system process GO:0002376 241 0.012
cell cell adhesion GO:0098609 6 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
cellular amine metabolic process GO:0044106 2 0.012
cell motility GO:0048870 244 0.012
superoxide metabolic process GO:0006801 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
neural retina development GO:0003407 49 0.012
gas transport GO:0015669 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
urogenital system development GO:0001655 97 0.012
regulation of protein targeting GO:1903533 2 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
steroid hormone mediated signaling pathway GO:0043401 9 0.012
organophosphate metabolic process GO:0019637 37 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.012
regulation of response to biotic stimulus GO:0002831 2 0.011
otic vesicle formation GO:0030916 27 0.011
neuron differentiation GO:0030182 353 0.011
otic vesicle development GO:0071599 42 0.011
cellular response to hypoxia GO:0071456 1 0.011
kidney development GO:0001822 92 0.011
immune system development GO:0002520 191 0.011
anatomical structure homeostasis GO:0060249 36 0.011
multicellular organismal water homeostasis GO:0050891 1 0.011
phosphorus metabolic process GO:0006793 109 0.011
pigment cell differentiation GO:0050931 38 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
actin filament based movement GO:0030048 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
death GO:0016265 121 0.011
otic vesicle morphogenesis GO:0071600 34 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cellular component movement GO:0006928 335 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of cellular component organization GO:0051128 86 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
appendage morphogenesis GO:0035107 56 0.010
lipid biosynthetic process GO:0008610 22 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
pigment cell development GO:0070285 3 0.010
tube formation GO:0035148 25 0.010
Zebrafish
wnt signaling pathway GO:0016055 80 0.010
response to radiation GO:0009314 51 0.010
regulation of catalytic activity GO:0050790 55 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
hemopoiesis GO:0030097 183 0.010
neuronal action potential GO:0019228 18 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
forebrain development GO:0030900 96 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
ribose phosphate biosynthetic process GO:0046390 20 0.010
multi organism reproductive process GO:0044703 36 0.010

cldnh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
auditory system disease DOID:2742 0 0.019
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.019
nonsyndromic deafness DOID:0050563 0 0.019
sensory system disease DOID:0050155 0 0.019
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.013
amyloidosis DOID:9120 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
bone disease DOID:0080001 0 0.010
connective tissue disease DOID:65 0 0.010