Danio rerio

18 known processes

nlgn1

neuroligin 1

nlgn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron neuron synaptic transmission GO:0007270 1 0.830
response to food GO:0032094 1 0.731
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.680
monoamine transport GO:0015844 1 0.678
regulation of multicellular organismal process GO:0051239 277 0.610
gabaergic neuron differentiation GO:0097154 2 0.593
nucleobase containing compound metabolic process GO:0006139 274 0.552
nucleic acid metabolic process GO:0090304 244 0.506
neuron differentiation GO:0030182 353 0.489
negative regulation of camp biosynthetic process GO:0030818 7 0.462
adult behavior GO:0030534 2 0.435
circadian sleep wake cycle process GO:0022410 2 0.434
transmembrane transport GO:0055085 120 0.408
nitrogen compound metabolic process GO:0006807 319 0.403
response to amphetamine GO:0001975 1 0.398
positive regulation of cellular process GO:0048522 201 0.346
regulation of macromolecule metabolic process GO:0060255 317 0.318
positive regulation of transport GO:0051050 2 0.305
nucleotide biosynthetic process GO:0009165 21 0.303
biosynthetic process GO:0009058 294 0.298
single organism behavior GO:0044708 24 0.296
cognition GO:0050890 1 0.278
regulation of synapse organization GO:0050807 3 0.276
nitrogen compound transport GO:0071705 23 0.272
cellular macromolecule metabolic process GO:0044260 391 0.272
negative regulation of purine nucleotide biosynthetic process GO:1900372 7 0.248
cellular macromolecule biosynthetic process GO:0034645 224 0.228
cell cell signaling GO:0007267 52 0.220
regulation of synaptic plasticity GO:0048167 1 0.218
g protein coupled receptor signaling pathway GO:0007186 74 0.206
regulation of camp metabolic process GO:0030814 9 0.200
mechanosensory behavior GO:0007638 2 0.196
regulation of camp biosynthetic process GO:0030817 9 0.192
negative regulation of protein kinase b signaling GO:0051898 2 0.191
lipid catabolic process GO:0016042 4 0.191
response to alkaloid GO:0043279 2 0.185
regulation of circadian sleep wake cycle GO:0042749 1 0.184
regulation of cellular metabolic process GO:0031323 320 0.183
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.177
hypothalamus development GO:0021854 14 0.177
sleep GO:0030431 1 0.176
generation of neurons GO:0048699 385 0.174
positive regulation of biological process GO:0048518 253 0.170
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.169
single organism localization GO:1902578 225 0.169
diencephalon development GO:0021536 58 0.166
regulation of response to nutrient levels GO:0032107 1 0.161
cellular biosynthetic process GO:0044249 286 0.158
negative regulation of hormone secretion GO:0046888 2 0.158
cellular aromatic compound metabolic process GO:0006725 295 0.155
heterocycle metabolic process GO:0046483 290 0.148
heterocycle biosynthetic process GO:0018130 215 0.147
cellular nitrogen compound metabolic process GO:0034641 290 0.141
circadian sleep wake cycle GO:0042745 2 0.141
regulation of system process GO:0044057 40 0.140
locomotory behavior GO:0007626 34 0.138
negative regulation of secretion by cell GO:1903531 2 0.127
system process GO:0003008 185 0.125
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.118
negative regulation of secretion GO:0051048 2 0.115
regulation of transmembrane transport GO:0034762 18 0.115
gene expression GO:0010467 252 0.109
response to abiotic stimulus GO:0009628 122 0.109
regulation of response to stimulus GO:0048583 269 0.106
negative regulation of lyase activity GO:0051350 6 0.106
regulation of cyclase activity GO:0031279 12 0.105
organic cyclic compound metabolic process GO:1901360 301 0.098
regulation of localization GO:0032879 104 0.097
regulation of adenylate cyclase activity GO:0045761 6 0.094
regulation of rna metabolic process GO:0051252 224 0.093
cell part morphogenesis GO:0032990 246 0.091
regulation of developmental process GO:0050793 247 0.090
regulation of postsynaptic membrane potential GO:0060078 1 0.089
transport GO:0006810 220 0.086
catecholamine metabolic process GO:0006584 2 0.086
small molecule metabolic process GO:0044281 77 0.083
neuron development GO:0048666 262 0.081
dopamine metabolic process GO:0042417 2 0.080
growth GO:0040007 174 0.078
regulation of reproductive process GO:2000241 4 0.078
regulation of multicellular organismal development GO:2000026 223 0.078
response to chemical GO:0042221 320 0.077
cellular nitrogen compound biosynthetic process GO:0044271 218 0.077
regulation of lyase activity GO:0051339 12 0.077
positive regulation of cell communication GO:0010647 56 0.076
negative regulation of purine nucleotide metabolic process GO:1900543 7 0.076
adrenergic receptor signaling pathway GO:0071875 5 0.075
response to ketone GO:1901654 1 0.075
locomotion GO:0040011 313 0.073
signal transduction GO:0007165 455 0.072
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.072
regulation of transporter activity GO:0032409 2 0.071
oxoacid metabolic process GO:0043436 31 0.071
response to drug GO:0042493 3 0.070
carbohydrate derivative biosynthetic process GO:1901137 43 0.070
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.069
circadian sleep wake cycle sleep GO:0050802 1 0.068
regulation of response to oxidative stress GO:1902882 2 0.068
ion transmembrane transport GO:0034220 91 0.066
regulation of circadian rhythm GO:0042752 4 0.066
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.065
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.065
regulation of signaling GO:0023051 235 0.064
behavior GO:0007610 74 0.063
camp metabolic process GO:0046058 11 0.063
sensory perception GO:0007600 39 0.060
rna biosynthetic process GO:0032774 181 0.059
regulation of hormone secretion GO:0046883 2 0.059
negative regulation of camp metabolic process GO:0030815 7 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.058
establishment of localization GO:0051234 244 0.058
single organism transport GO:0044765 206 0.056
amide transport GO:0042886 12 0.056
regulation of transport GO:0051049 45 0.055
macromolecule biosynthetic process GO:0009059 227 0.055
negative regulation of response to stimulus GO:0048585 104 0.054
negative regulation of adenylate cyclase activity GO:0007194 6 0.054
cellular response to reactive oxygen species GO:0034614 2 0.054
multicellular organismal response to stress GO:0033555 2 0.054
forebrain cell migration GO:0021885 1 0.054
steroid hormone mediated signaling pathway GO:0043401 9 0.053
negative regulation of signaling GO:0023057 96 0.051
smooth muscle contraction GO:0006939 2 0.051
aromatic compound biosynthetic process GO:0019438 217 0.049
response to organic substance GO:0010033 153 0.048
response to amine GO:0014075 1 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.047
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.047
regulation of primary metabolic process GO:0080090 311 0.046
neuron projection morphogenesis GO:0048812 161 0.046
regulation of ion transport GO:0043269 22 0.046
multicellular organismal water homeostasis GO:0050891 1 0.045
negative regulation of biological process GO:0048519 304 0.044
nucleoside phosphate biosynthetic process GO:1901293 21 0.044
positive regulation of biosynthetic process GO:0009891 68 0.044
peptide transport GO:0015833 1 0.043
neuron projection development GO:0031175 180 0.043
regulation of tube size GO:0035150 2 0.043
regulation of protein complex assembly GO:0043254 3 0.042
regulation of neurogenesis GO:0050767 87 0.042
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.042
regulation of calcium ion transport GO:0051924 2 0.042
muscle contraction GO:0006936 18 0.042
regulation of fatty acid metabolic process GO:0019217 1 0.042
cellular lipid metabolic process GO:0044255 36 0.041
blood circulation GO:0008015 87 0.040
negative regulation of catabolic process GO:0009895 3 0.040
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.039
purine ribonucleotide biosynthetic process GO:0009152 20 0.038
response to hexose GO:0009746 3 0.038
organonitrogen compound biosynthetic process GO:1901566 47 0.037
regulation of cell communication GO:0010646 232 0.037
negative regulation of protein transport GO:0051224 3 0.037
regulation of metabolic process GO:0019222 359 0.037
regulation of ion transmembrane transport GO:0034765 18 0.037
regulation of metal ion transport GO:0010959 4 0.037
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
neurological system process GO:0050877 62 0.036
electron transport chain GO:0022900 2 0.036
response to inorganic substance GO:0010035 38 0.036
single organism metabolic process GO:0044710 217 0.036
response to carbohydrate GO:0009743 3 0.036
positive regulation of secretion GO:0051047 1 0.036
regulation of cell differentiation GO:0045595 142 0.036
regulation of gene expression GO:0010468 265 0.035
regulation of locomotion GO:0040012 55 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
negative regulation of feeding behavior GO:2000252 2 0.033
neurotransmitter secretion GO:0007269 2 0.032
eye development GO:0001654 277 0.032
organic substance biosynthetic process GO:1901576 289 0.032
neurotransmitter transport GO:0006836 2 0.032
cell projection organization GO:0030030 284 0.031
organic hydroxy compound transport GO:0015850 14 0.031
positive regulation of metabolic process GO:0009893 108 0.031
neuron projection guidance GO:0097485 86 0.031
central nervous system neuron development GO:0021954 29 0.031
regulation of biological quality GO:0065008 263 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
regulation of transmembrane transporter activity GO:0022898 2 0.031
catechol containing compound metabolic process GO:0009712 2 0.031
rna metabolic process GO:0016070 219 0.030
regulation of signal transduction GO:0009966 225 0.030
amino acid transport GO:0006865 2 0.030
hemopoiesis GO:0030097 183 0.030
regulation of neurological system process GO:0031644 2 0.030
muscle system process GO:0003012 20 0.029
response to light stimulus GO:0009416 46 0.029
regulation of inhibitory postsynaptic membrane potential GO:0060080 1 0.029
cellular response to organic cyclic compound GO:0071407 38 0.029
positive regulation of secretion by cell GO:1903532 1 0.029
positive regulation of response to stimulus GO:0048584 80 0.029
gastrulation GO:0007369 208 0.028
cellular aldehyde metabolic process GO:0006081 4 0.028
cellular component movement GO:0006928 335 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
neuromuscular synaptic transmission GO:0007274 2 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
synaptic transmission glycinergic GO:0060012 1 0.027
multicellular organism growth GO:0035264 4 0.027
sensory perception of pain GO:0019233 1 0.027
reflex GO:0060004 2 0.026
fatty acid oxidation GO:0019395 1 0.026
regulation of dendrite development GO:0050773 3 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
nucleic acid templated transcription GO:0097659 181 0.026
female gonad development GO:0008585 4 0.026
synaptic transmission GO:0007268 35 0.025
establishment of localization in cell GO:0051649 77 0.025
alpha amino acid metabolic process GO:1901605 3 0.025
positive regulation of gene expression GO:0010628 71 0.025
regulation of purine nucleotide metabolic process GO:1900542 17 0.024
developmental growth GO:0048589 166 0.024
oxidation reduction process GO:0055114 41 0.024
regulation of glutamate receptor signaling pathway GO:1900449 1 0.024
positive regulation of dna metabolic process GO:0051054 1 0.024
regulation of axon extension GO:0030516 24 0.024
hormone secretion GO:0046879 2 0.024
embryonic skeletal joint morphogenesis GO:0060272 3 0.024
regulation of heart rate GO:0002027 5 0.024
regulation of protein catabolic process GO:0042176 1 0.023
regulation of response to extracellular stimulus GO:0032104 1 0.023
cranial nerve development GO:0021545 42 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
brain development GO:0007420 293 0.023
cellular amine metabolic process GO:0044106 2 0.023
macromolecule modification GO:0043412 111 0.022
response to external stimulus GO:0009605 264 0.022
regulation of blood pressure GO:0008217 1 0.022
positive regulation of neuron migration GO:2001224 2 0.022
positive regulation of catabolic process GO:0009896 4 0.022
cellular amino acid metabolic process GO:0006520 7 0.021
negative regulation of cyclase activity GO:0031280 6 0.021
embryonic skeletal joint development GO:0072498 3 0.021
cation transmembrane transport GO:0098655 65 0.021
ion transport GO:0006811 114 0.021
purine nucleotide biosynthetic process GO:0006164 20 0.021
regulation of blood circulation GO:1903522 32 0.021
ribonucleotide biosynthetic process GO:0009260 20 0.021
cellular response to hormone stimulus GO:0032870 39 0.020
branching morphogenesis of a nerve GO:0048755 4 0.020
response to monosaccharide GO:0034284 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
circulatory system process GO:0003013 87 0.019
neuron migration GO:0001764 22 0.019
maintenance of location GO:0051235 4 0.019
regulation of neuron differentiation GO:0045664 56 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
regulation of neuron projection development GO:0010975 40 0.019
transmission of nerve impulse GO:0019226 19 0.019
response to lipid GO:0033993 60 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
amine metabolic process GO:0009308 2 0.019
cellular response to organic substance GO:0071310 105 0.019
cellular response to oxygen levels GO:0071453 1 0.019
fertilization GO:0009566 3 0.018
carbohydrate homeostasis GO:0033500 1 0.018
cellular protein modification process GO:0006464 100 0.018
cellular respiration GO:0045333 3 0.018
anion transport GO:0006820 38 0.018
purine nucleotide metabolic process GO:0006163 27 0.018
fatty acid transport GO:0015908 1 0.018
regulation of cell motility GO:2000145 46 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
negative regulation of cellular process GO:0048523 283 0.018
nucleobase containing small molecule metabolic process GO:0055086 32 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.018
cell migration GO:0016477 237 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
rna splicing GO:0008380 16 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
response to endogenous stimulus GO:0009719 83 0.017
response to wounding GO:0009611 116 0.017
regulation of cell development GO:0060284 100 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
cellular response to lipid GO:0071396 39 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
hormone transport GO:0009914 2 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
regulation of catalytic activity GO:0050790 55 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
response to estrogen GO:0043627 27 0.016
regulation of molecular function GO:0065009 70 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
positive regulation of signaling GO:0023056 56 0.016
organic acid metabolic process GO:0006082 31 0.016
cellular response to estrogen stimulus GO:0071391 24 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.016
lipid metabolic process GO:0006629 52 0.016
response to dexamethasone GO:0071548 1 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
fatty acid beta oxidation GO:0006635 1 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
response to glucose GO:0009749 3 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.015
transcription dna templated GO:0006351 181 0.015
cell motility GO:0048870 244 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
positive regulation of gastrulation GO:2000543 2 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
developmental cell growth GO:0048588 52 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
cellular component morphogenesis GO:0032989 336 0.014
axonogenesis GO:0007409 152 0.014
forebrain development GO:0030900 96 0.014
feeding behavior GO:0007631 5 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of biosynthetic process GO:0009889 250 0.014
cellular response to hypoxia GO:0071456 1 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
membrane hyperpolarization GO:0060081 1 0.014
single organism biosynthetic process GO:0044711 71 0.014
protein metabolic process GO:0019538 183 0.014
glutamate receptor signaling pathway GO:0007215 1 0.013
negative regulation of behavior GO:0048521 6 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
cellular protein metabolic process GO:0044267 129 0.013
catechol containing compound biosynthetic process GO:0009713 2 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
hormone mediated signaling pathway GO:0009755 9 0.013
positive regulation of reproductive process GO:2000243 2 0.013
locomotor rhythm GO:0045475 3 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
glucose homeostasis GO:0042593 1 0.013
circadian rhythm GO:0007623 19 0.013
regulation of nervous system development GO:0051960 90 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
negative regulation of cell communication GO:0010648 96 0.012
cellular protein catabolic process GO:0044257 4 0.012
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.012
postsynaptic membrane organization GO:0001941 3 0.012
central nervous system neuron axonogenesis GO:0021955 18 0.012
response to radiation GO:0009314 51 0.012
exocytosis GO:0006887 1 0.012
ventral spinal cord development GO:0021517 35 0.012
regulation of nucleotide biosynthetic process GO:0030808 15 0.012
camp biosynthetic process GO:0006171 11 0.012
regulation of growth GO:0040008 42 0.012
negative regulation of cell fate specification GO:0009996 11 0.012
regulation of embryonic development GO:0045995 47 0.012
chemical homeostasis GO:0048878 49 0.012
response to alcohol GO:0097305 14 0.012
embryonic organ development GO:0048568 381 0.012
regulation of organ growth GO:0046620 3 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
cellular ketone metabolic process GO:0042180 11 0.011
chemotaxis GO:0006935 104 0.011
localization of cell GO:0051674 244 0.011
cyclic nucleotide metabolic process GO:0009187 18 0.011
cyclic nucleotide biosynthetic process GO:0009190 18 0.011
positive regulation of wound healing GO:0090303 1 0.011
regulation of protein transport GO:0051223 3 0.011
protein localization to nucleus GO:0034504 3 0.011
negative regulation of reproductive process GO:2000242 3 0.011
purine containing compound biosynthetic process GO:0072522 20 0.011
positive regulation of cellular protein metabolic process GO:0032270 22 0.011
muscle hypertrophy GO:0014896 2 0.011
chromosome organization GO:0051276 31 0.011
macroautophagy GO:0016236 1 0.011
regulation of mrna processing GO:0050684 3 0.011
circadian regulation of gene expression GO:0032922 8 0.011
regulation of synapse structure and activity GO:0050803 5 0.011
purine containing compound metabolic process GO:0072521 29 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
carboxylic acid catabolic process GO:0046395 3 0.010
positive regulation of cell growth GO:0030307 5 0.010
multi organism process GO:0051704 134 0.010
response to corticosteroid GO:0031960 1 0.010
intracellular receptor signaling pathway GO:0030522 30 0.010

nlgn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.122
autistic disorder DOID:12849 0 0.104
pervasive developmental disorder DOID:0060040 0 0.104
autism spectrum disorder DOID:0060041 0 0.104
disease of mental health DOID:150 0 0.104
developmental disorder of mental health DOID:0060037 0 0.104