Danio rerio

0 known processes

cldn8

claudin 8

(Aliases: wu:fa01e05,zgc:91900)

cldn8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral line system development GO:0048925 76 0.315
positive regulation of biological process GO:0048518 253 0.210
organic cyclic compound metabolic process GO:1901360 301 0.160
sensory organ development GO:0007423 393 0.154
aging GO:0007568 2 0.142
response to antibiotic GO:0046677 1 0.137
larval development GO:0002164 2 0.126
establishment of endothelial barrier GO:0061028 3 0.123
morphogenesis of an epithelium GO:0002009 333 0.108
cation transport GO:0006812 81 0.106
regulation of metal ion transport GO:0010959 4 0.102
regulation of sodium ion transport GO:0002028 2 0.098
neuromast development GO:0048884 46 0.098
response to ketone GO:1901654 1 0.096
regulation of multicellular organismal process GO:0051239 277 0.094
cellular response to antibiotic GO:0071236 1 0.092
cognition GO:0050890 1 0.087
biosynthetic process GO:0009058 294 0.085
digestive tract morphogenesis GO:0048546 231 0.085
long chain fatty acid transport GO:0015909 1 0.085
response to glucocorticoid GO:0051384 1 0.083
single organism localization GO:1902578 225 0.082
gastrulation GO:0007369 208 0.081
cellular biosynthetic process GO:0044249 286 0.079
cellular aromatic compound metabolic process GO:0006725 295 0.077
neurological system process GO:0050877 62 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.073
regionalization GO:0003002 274 0.073
epithelial cell differentiation GO:0030855 116 0.073
digestive tract development GO:0048565 265 0.072
nitrogen compound metabolic process GO:0006807 319 0.072
sensory system development GO:0048880 76 0.072
female sex differentiation GO:0046660 4 0.072
alpha amino acid metabolic process GO:1901605 3 0.071
regulation of rna metabolic process GO:0051252 224 0.070
lateral line development GO:0048882 66 0.070
gastrulation with mouth forming second GO:0001702 44 0.070
ion transport GO:0006811 114 0.069
alcohol biosynthetic process GO:0046165 2 0.069
response to chemical GO:0042221 320 0.068
metal ion transport GO:0030001 58 0.066
digestive system development GO:0055123 289 0.065
gland development GO:0048732 143 0.064
phosphate containing compound metabolic process GO:0006796 108 0.063
organonitrogen compound metabolic process GO:1901564 74 0.063
carbohydrate derivative biosynthetic process GO:1901137 43 0.062
system process GO:0003008 185 0.062
secondary metabolic process GO:0019748 3 0.061
maintenance of location GO:0051235 4 0.057
carbohydrate derivative metabolic process GO:1901135 61 0.055
positive regulation of transport GO:0051050 2 0.054
establishment of localization GO:0051234 244 0.052
amine metabolic process GO:0009308 2 0.052
female gonad development GO:0008585 4 0.051
tube morphogenesis GO:0035239 349 0.050
cellular macromolecule biosynthetic process GO:0034645 224 0.048
response to glucose GO:0009749 3 0.048
heterocycle metabolic process GO:0046483 290 0.048
response to drug GO:0042493 3 0.048
morphogenesis of an epithelial sheet GO:0002011 49 0.047
regulation of gene expression GO:0010468 265 0.047
organic substance biosynthetic process GO:1901576 289 0.046
regulation of biological quality GO:0065008 263 0.045
macromolecule biosynthetic process GO:0009059 227 0.044
fatty acid transport GO:0015908 1 0.043
locomotion GO:0040011 313 0.043
heart development GO:0007507 313 0.043
generation of neurons GO:0048699 385 0.043
cellular component movement GO:0006928 335 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.042
positive regulation of biosynthetic process GO:0009891 68 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
neuron differentiation GO:0030182 353 0.041
regulation of rna biosynthetic process GO:2001141 213 0.040
aromatic compound biosynthetic process GO:0019438 217 0.040
organic acid metabolic process GO:0006082 31 0.040
development of primary female sexual characteristics GO:0046545 4 0.039
response to monosaccharide GO:0034284 3 0.039
regulation of synapse assembly GO:0051963 3 0.038
epithelial cell development GO:0002064 42 0.038
organic cyclic compound biosynthetic process GO:1901362 223 0.038
oxoacid metabolic process GO:0043436 31 0.038
androgen biosynthetic process GO:0006702 1 0.037
brain development GO:0007420 293 0.037
regulation of blood pressure GO:0008217 1 0.037
regulation of metabolic process GO:0019222 359 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
single organism metabolic process GO:0044710 217 0.036
head development GO:0060322 303 0.035
adult behavior GO:0030534 2 0.035
sodium ion transport GO:0006814 24 0.035
regulation of cytoplasmic transport GO:1903649 4 0.035
single fertilization GO:0007338 3 0.035
central nervous system development GO:0007417 387 0.034
cell projection morphogenesis GO:0048858 244 0.034
transport GO:0006810 220 0.034
lipid storage GO:0019915 1 0.033
regulation of protein transport GO:0051223 3 0.033
long chain fatty acid metabolic process GO:0001676 1 0.033
protein localization to nucleus GO:0034504 3 0.033
neurotransmitter secretion GO:0007269 2 0.033
cellular component biogenesis GO:0044085 178 0.032
single organism transport GO:0044765 206 0.032
cell morphogenesis GO:0000902 289 0.032
regulation of developmental process GO:0050793 247 0.031
calcium ion transport GO:0006816 18 0.031
chemotaxis GO:0006935 104 0.031
response to steroid hormone GO:0048545 35 0.031
endosomal transport GO:0016197 2 0.031
small molecule metabolic process GO:0044281 77 0.030
response to corticosteroid GO:0031960 1 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
regulation of system process GO:0044057 40 0.030
cyclic purine nucleotide metabolic process GO:0052652 18 0.030
dicarboxylic acid metabolic process GO:0043648 1 0.030
single organism biosynthetic process GO:0044711 71 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
gene expression GO:0010467 252 0.028
regulation of cell shape GO:0008360 1 0.028
ribonucleoside monophosphate catabolic process GO:0009158 4 0.028
anterior posterior pattern specification GO:0009952 152 0.028
single organism organelle organization GO:1902589 199 0.028
negative regulation of biological process GO:0048519 304 0.028
taxis GO:0042330 109 0.028
positive regulation of cellular process GO:0048522 201 0.027
negative regulation of secretion by cell GO:1903531 2 0.027
muscle structure development GO:0061061 196 0.027
odontogenesis of dentin containing tooth GO:0042475 1 0.027
regulation of synapse organization GO:0050807 3 0.027
nephron tubule morphogenesis GO:0072078 1 0.027
atp catabolic process GO:0006200 4 0.027
regulation of hormone secretion GO:0046883 2 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of protein complex assembly GO:0043254 3 0.026
cell migration GO:0016477 237 0.026
cellular amine metabolic process GO:0044106 2 0.026
response to organic substance GO:0010033 153 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
cell part morphogenesis GO:0032990 246 0.026
cellular ketone metabolic process GO:0042180 11 0.026
response to xenobiotic stimulus GO:0009410 45 0.026
cellular amino acid metabolic process GO:0006520 7 0.026
androgen metabolic process GO:0008209 2 0.025
glycoprotein metabolic process GO:0009100 23 0.025
renal tubule morphogenesis GO:0061333 1 0.025
response to vitamin GO:0033273 3 0.024
cellular component morphogenesis GO:0032989 336 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
sensory organ morphogenesis GO:0090596 200 0.024
regulation of tube size GO:0035150 2 0.024
hindbrain development GO:0030902 91 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of reproductive process GO:2000241 4 0.023
homeostatic process GO:0042592 142 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
circulatory system process GO:0003013 87 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
blood circulation GO:0008015 87 0.022
ovarian follicle development GO:0001541 2 0.022
fertilization GO:0009566 3 0.022
cytokinesis GO:0000910 3 0.022
neurotransmitter transport GO:0006836 2 0.022
mitochondrion organization GO:0007005 4 0.022
regulation of primary metabolic process GO:0080090 311 0.022
regulation of signaling GO:0023051 235 0.022
cell motility GO:0048870 244 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
exocytosis GO:0006887 1 0.021
post embryonic organ development GO:0048569 4 0.021
rna metabolic process GO:0016070 219 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
nuclear import GO:0051170 3 0.021
lipid metabolic process GO:0006629 52 0.021
regulation of cell communication GO:0010646 232 0.021
immune system process GO:0002376 241 0.021
intracellular estrogen receptor signaling pathway GO:0030520 3 0.021
inner ear development GO:0048839 126 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
negative regulation of cellular process GO:0048523 283 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
nucleic acid metabolic process GO:0090304 244 0.020
nucleic acid templated transcription GO:0097659 181 0.020
epiboly GO:0090504 41 0.020
stem cell maintenance GO:0019827 4 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
cell projection organization GO:0030030 284 0.020
positive regulation of gene expression GO:0010628 71 0.020
divalent inorganic cation transport GO:0072511 21 0.020
embryonic organ development GO:0048568 381 0.020
nucleocytoplasmic transport GO:0006913 4 0.019
nuclear transport GO:0051169 4 0.019
protein targeting to nucleus GO:0044744 3 0.019
hormone transport GO:0009914 2 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
regulation of transcription dna templated GO:0006355 213 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
negative regulation of secretion GO:0051048 2 0.019
neuroblast proliferation GO:0007405 2 0.019
hormone biosynthetic process GO:0042446 3 0.019
regulation of signal transduction GO:0009966 225 0.019
neuron development GO:0048666 262 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.018
muscle tissue development GO:0060537 110 0.018
glial cell migration GO:0008347 3 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
response to carbohydrate GO:0009743 3 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
negative regulation of hormone secretion GO:0046888 2 0.018
regulation of biosynthetic process GO:0009889 250 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
ear development GO:0043583 127 0.018
signal transduction GO:0007165 455 0.018
ovulation cycle GO:0042698 2 0.018
positive regulation of transcription dna templated GO:0045893 57 0.017
response to external stimulus GO:0009605 264 0.017
positive regulation of camp biosynthetic process GO:0030819 2 0.017
regulation of localization GO:0032879 104 0.017
organelle organization GO:0006996 227 0.017
stem cell proliferation GO:0072089 4 0.017
chemosensory behavior GO:0007635 1 0.017
response to alkaloid GO:0043279 2 0.017
meiotic nuclear division GO:0007126 4 0.017
neuron projection morphogenesis GO:0048812 161 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
ovulation cycle process GO:0022602 2 0.017
toxin metabolic process GO:0009404 1 0.017
response to hormone GO:0009725 48 0.017
protein polymerization GO:0051258 4 0.017
positive regulation of cellular biosynthetic process GO:0031328 68 0.017
regulation of muscle contraction GO:0006937 3 0.017
hormone secretion GO:0046879 2 0.017
forebrain development GO:0030900 96 0.017
intracellular receptor signaling pathway GO:0030522 30 0.017
positive regulation of rna metabolic process GO:0051254 59 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
protein metabolic process GO:0019538 183 0.016
cell proliferation GO:0008283 80 0.016
dna templated transcription elongation GO:0006354 3 0.016
alternative mrna splicing via spliceosome GO:0000380 1 0.016
transcription dna templated GO:0006351 181 0.016
water homeostasis GO:0030104 4 0.016
response to oxygen containing compound GO:1901700 55 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
rna biosynthetic process GO:0032774 181 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
neuron projection guidance GO:0097485 86 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
single organism nuclear import GO:1902593 3 0.016
axon guidance GO:0007411 86 0.016
ameboidal type cell migration GO:0001667 143 0.016
muscle cell migration GO:0014812 4 0.016
axonogenesis GO:0007409 152 0.016
nephron epithelium morphogenesis GO:0072088 1 0.016
immune system development GO:0002520 191 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
intracellular signal transduction GO:0035556 85 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
cortical granule exocytosis GO:0060471 1 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
localization of cell GO:0051674 244 0.016
regulation of blood vessel size GO:0050880 2 0.015
chemical homeostasis GO:0048878 49 0.015
interspecies interaction between organisms GO:0044419 4 0.015
polyol metabolic process GO:0019751 1 0.015
protein import GO:0017038 3 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
muscle contraction GO:0006936 18 0.015
eye development GO:0001654 277 0.015
protein import into nucleus GO:0006606 3 0.015
purine nucleotide metabolic process GO:0006163 27 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of filopodium assembly GO:0051489 2 0.015
regulation of cell projection assembly GO:0060491 4 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
endothelial cell development GO:0001885 12 0.015
axon development GO:0061564 166 0.015
glycoprotein biosynthetic process GO:0009101 21 0.015
response to endogenous stimulus GO:0009719 83 0.015
peptidyl serine modification GO:0018209 2 0.015
response to hexose GO:0009746 3 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
skeletal system development GO:0001501 181 0.015
aflatoxin b1 metabolic process GO:0043390 1 0.015
cell substrate adhesion GO:0031589 4 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
multicellular organismal response to stress GO:0033555 2 0.014
negative regulation of reproductive process GO:2000242 3 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
nucleotide biosynthetic process GO:0009165 21 0.014
response to nutrient GO:0007584 3 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of cell differentiation GO:0045595 142 0.014
positive regulation of carbohydrate metabolic process GO:0045913 1 0.014
cellular component assembly GO:0022607 170 0.014
regulation of transport GO:0051049 45 0.014
cellular response to starvation GO:0009267 1 0.014
organophosphate biosynthetic process GO:0090407 23 0.014
monovalent inorganic cation transport GO:0015672 42 0.014
response to inorganic substance GO:0010035 38 0.014
response to stress GO:0006950 263 0.014
cellular response to external stimulus GO:0071496 2 0.014
positive regulation of secretion GO:0051047 1 0.014
kidney development GO:0001822 92 0.014
response to hydrogen peroxide GO:0042542 3 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
positive regulation of cell cycle GO:0045787 3 0.014
response to abiotic stimulus GO:0009628 122 0.014
sensory perception of chemical stimulus GO:0007606 3 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
positive regulation of metabolic process GO:0009893 108 0.013
apical junction assembly GO:0043297 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
biological adhesion GO:0022610 40 0.013
axis specification GO:0009798 43 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
endothelium development GO:0003158 25 0.013
spermatid development GO:0007286 2 0.013
gtp metabolic process GO:0046039 4 0.013
regulation of transporter activity GO:0032409 2 0.013
tissue remodeling GO:0048771 4 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
cellular response to estrogen stimulus GO:0071391 24 0.013
tube closure GO:0060606 1 0.013
retina development in camera type eye GO:0060041 146 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
cation transmembrane transport GO:0098655 65 0.013
calcium mediated signaling GO:0019722 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
wound healing GO:0042060 90 0.012
protein localization to vacuole GO:0072665 1 0.012
cellular response to organic substance GO:0071310 105 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
exocrine system development GO:0035272 28 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
ear morphogenesis GO:0042471 64 0.012
cellular chemical homeostasis GO:0055082 17 0.012
regulation of receptor activity GO:0010469 2 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
response to organic cyclic compound GO:0014070 51 0.012
regulation of molecular function GO:0065009 70 0.012
negative regulation of signaling GO:0023057 96 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
membrane lipid biosynthetic process GO:0046467 2 0.011
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.011
determination of left right symmetry GO:0007368 179 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
eye morphogenesis GO:0048592 144 0.011
somatic muscle development GO:0007525 4 0.011
rna localization GO:0006403 4 0.011
vacuolar transport GO:0007034 2 0.011
response to radiation GO:0009314 51 0.011
viral process GO:0016032 1 0.011
camera type eye development GO:0043010 222 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
glucose homeostasis GO:0042593 1 0.011
multi organism cellular process GO:0044764 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
monoamine transport GO:0015844 1 0.011
oocyte maturation GO:0001556 4 0.011
endocrine process GO:0050886 2 0.010
regulation of cell activation GO:0050865 1 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
autophagy GO:0006914 4 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
regulation of protein polymerization GO:0032271 2 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
striated muscle contraction GO:0006941 12 0.010
regulation of endocrine process GO:0044060 2 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
negative regulation of developmental process GO:0051093 65 0.010
estrogen metabolic process GO:0008210 2 0.010
phosphorus metabolic process GO:0006793 109 0.010
cation homeostasis GO:0055080 33 0.010
purine containing compound biosynthetic process GO:0072522 20 0.010
segmentation GO:0035282 97 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
response to bacterium GO:0009617 58 0.010
rna 3 end processing GO:0031123 2 0.010
neuron projection development GO:0031175 180 0.010

cldn8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
nervous system disease DOID:863 0 0.012
organ system cancer DOID:0050686 0 0.011
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010