Danio rerio

0 known processes

insig2

insulin induced gene 2

insig2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.100
regulation of establishment of protein localization GO:0070201 4 0.077
regulation of biological quality GO:0065008 263 0.073
cellular biosynthetic process GO:0044249 286 0.071
signal transduction GO:0007165 455 0.069
nitrogen compound metabolic process GO:0006807 319 0.062
cellular response to organic substance GO:0071310 105 0.061
regulation of multicellular organismal development GO:2000026 223 0.060
cellular nitrogen compound metabolic process GO:0034641 290 0.058
single organism organelle organization GO:1902589 199 0.056
positive regulation of transport GO:0051050 2 0.055
cellular amine metabolic process GO:0044106 2 0.052
larval development GO:0002164 2 0.051
organic acid metabolic process GO:0006082 31 0.050
cell projection morphogenesis GO:0048858 244 0.049
cellular carbohydrate metabolic process GO:0044262 4 0.046
regulation of multicellular organismal process GO:0051239 277 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
single organism biosynthetic process GO:0044711 71 0.043
cell projection organization GO:0030030 284 0.042
multicellular organism growth GO:0035264 4 0.042
synaptic growth at neuromuscular junction GO:0051124 2 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
rna metabolic process GO:0016070 219 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.034
regulation of developmental process GO:0050793 247 0.034
thrombocyte differentiation GO:0002574 4 0.033
oxoacid metabolic process GO:0043436 31 0.033
vasculature development GO:0001944 278 0.033
cell morphogenesis GO:0000902 289 0.033
phosphorus metabolic process GO:0006793 109 0.032
cell part morphogenesis GO:0032990 246 0.032
aging GO:0007568 2 0.032
nucleic acid metabolic process GO:0090304 244 0.031
single organism metabolic process GO:0044710 217 0.030
small molecule metabolic process GO:0044281 77 0.029
mitochondrion organization GO:0007005 4 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
amine metabolic process GO:0009308 2 0.029
cognition GO:0050890 1 0.029
biosynthetic process GO:0009058 294 0.029
regulation of reproductive process GO:2000241 4 0.028
protein modification process GO:0036211 100 0.028
cellular macromolecule metabolic process GO:0044260 391 0.027
establishment of localization GO:0051234 244 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
maintenance of location GO:0051235 4 0.027
cellular response to external stimulus GO:0071496 2 0.027
regulation of response to stimulus GO:0048583 269 0.026
establishment of localization in cell GO:0051649 77 0.026
alcohol biosynthetic process GO:0046165 2 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of protein transport GO:0051223 3 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of cell communication GO:0010646 232 0.024
regulation of synapse organization GO:0050807 3 0.024
heterocycle metabolic process GO:0046483 290 0.024
lipid storage GO:0019915 1 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.023
carbohydrate biosynthetic process GO:0016051 1 0.023
locomotion GO:0040011 313 0.023
protein localization to nucleus GO:0034504 3 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
hypochord development GO:0055016 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.022
intracellular signal transduction GO:0035556 85 0.022
multicellular organismal response to stress GO:0033555 2 0.022
circadian sleep wake cycle process GO:0022410 2 0.022
regulation of signal transduction GO:0009966 225 0.022
autophagy GO:0006914 4 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of transcription dna templated GO:0006355 213 0.021
regulation of protein catabolic process GO:0042176 1 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
regulation of neuron migration GO:2001222 2 0.020
stem cell proliferation GO:0072089 4 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
organic substance biosynthetic process GO:1901576 289 0.020
regulation of cell projection organization GO:0031344 44 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
cellular ketone metabolic process GO:0042180 11 0.019
regulation of rna metabolic process GO:0051252 224 0.019
meiotic nuclear division GO:0007126 4 0.019
nuclear transport GO:0051169 4 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
generation of neurons GO:0048699 385 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
macromolecule modification GO:0043412 111 0.018
regulation of cell death GO:0010941 103 0.018
negative regulation of biological process GO:0048519 304 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of metabolic process GO:0019222 359 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
protein acylation GO:0043543 3 0.017
positive regulation of catabolic process GO:0009896 4 0.017
neurotransmitter transport GO:0006836 2 0.017
cellular response to endogenous stimulus GO:0071495 68 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
protein import GO:0017038 3 0.017
cellular protein modification process GO:0006464 100 0.017
neuron projection morphogenesis GO:0048812 161 0.016
regulation of autophagy GO:0010506 3 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
axon development GO:0061564 166 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
death GO:0016265 121 0.016
transport GO:0006810 220 0.015
growth GO:0040007 174 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
cellular response to organic cyclic compound GO:0071407 38 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
organelle organization GO:0006996 227 0.015
cellular response to growth factor stimulus GO:0071363 39 0.014
developmental growth GO:0048589 166 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
single organism transport GO:0044765 206 0.014
neuron development GO:0048666 262 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
response to wounding GO:0009611 116 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
establishment of organelle localization GO:0051656 45 0.014
response to external stimulus GO:0009605 264 0.014
homeostatic process GO:0042592 142 0.014
eye development GO:0001654 277 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of circadian rhythm GO:0042752 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
cell migration GO:0016477 237 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
positive regulation of biological process GO:0048518 253 0.013
cellular component assembly GO:0022607 170 0.013
response to alkaloid GO:0043279 2 0.013
response to radiation GO:0009314 51 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
programmed cell death GO:0012501 119 0.013
sensory organ development GO:0007423 393 0.013
blood vessel development GO:0001568 246 0.013
regulation of growth GO:0040008 42 0.013
wound healing GO:0042060 90 0.013
small molecule biosynthetic process GO:0044283 16 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
myeloid cell differentiation GO:0030099 86 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
cellular component movement GO:0006928 335 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
response to light stimulus GO:0009416 46 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of synapse assembly GO:0051963 3 0.012
positive regulation of reproductive process GO:2000243 2 0.012
regulation of response to external stimulus GO:0032101 31 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
nuclear import GO:0051170 3 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
cellular localization GO:0051641 97 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
endocardial cushion formation GO:0003272 2 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cilium morphogenesis GO:0060271 85 0.011
negative regulation of cellular process GO:0048523 283 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
response to stress GO:0006950 263 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
gene expression GO:0010467 252 0.010
cellular protein catabolic process GO:0044257 4 0.010
hormone secretion GO:0046879 2 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
response to hormone GO:0009725 48 0.010
embryonic skeletal system development GO:0048706 97 0.010
regulation of developmental growth GO:0048638 38 0.010
negative regulation of multi organism process GO:0043901 3 0.010
protein import into nucleus GO:0006606 3 0.010

insig2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
disease of metabolism DOID:0014667 0 0.012