Danio rerio

0 known processes

dyrk2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

(Aliases: wu:fc18c09,si:ch211-266a5.8,wu:fa09g03,fc18c09)

dyrk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.065
positive regulation of transport GO:0051050 2 0.053
embryonic organ morphogenesis GO:0048562 274 0.042
aging GO:0007568 2 0.041
cellular amine metabolic process GO:0044106 2 0.039
amine metabolic process GO:0009308 2 0.038
maintenance of location GO:0051235 4 0.037
regulation of synapse organization GO:0050807 3 0.037
sensory organ development GO:0007423 393 0.036
cell part morphogenesis GO:0032990 246 0.033
regulation of protein transport GO:0051223 3 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
multicellular organism growth GO:0035264 4 0.032
cell projection organization GO:0030030 284 0.032
positive regulation of cell cycle GO:0045787 3 0.031
embryonic organ development GO:0048568 381 0.031
nuclear transport GO:0051169 4 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
cellular ketone metabolic process GO:0042180 11 0.029
stem cell proliferation GO:0072089 4 0.029
nucleic acid metabolic process GO:0090304 244 0.028
heterocycle metabolic process GO:0046483 290 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
central nervous system development GO:0007417 387 0.028
specification of symmetry GO:0009799 204 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
cognition GO:0050890 1 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
cellular component morphogenesis GO:0032989 336 0.027
positive regulation of catabolic process GO:0009896 4 0.026
regulation of synapse assembly GO:0051963 3 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
rna metabolic process GO:0016070 219 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
gtp catabolic process GO:0006184 2 0.025
eye development GO:0001654 277 0.025
mitochondrion organization GO:0007005 4 0.025
neuron differentiation GO:0030182 353 0.024
adult behavior GO:0030534 2 0.024
cell morphogenesis GO:0000902 289 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of protein complex assembly GO:0043254 3 0.024
exocytosis GO:0006887 1 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
lipid storage GO:0019915 1 0.023
regulation of binding GO:0051098 3 0.023
regulation of cytokine production GO:0001817 3 0.023
cell projection morphogenesis GO:0048858 244 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
neuron development GO:0048666 262 0.023
cellular component disassembly GO:0022411 1 0.023
protein localization to nucleus GO:0034504 3 0.023
gene expression GO:0010467 252 0.023
camera type eye development GO:0043010 222 0.023
cellular component movement GO:0006928 335 0.023
organic substance biosynthetic process GO:1901576 289 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
stem cell maintenance GO:0019827 4 0.022
biosynthetic process GO:0009058 294 0.022
cytokinesis GO:0000910 3 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
regulation of metabolic process GO:0019222 359 0.021
signal transduction GO:0007165 455 0.021
autophagy GO:0006914 4 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
heart development GO:0007507 313 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
neuroblast proliferation GO:0007405 2 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
transcription dna templated GO:0006351 181 0.021
locomotion GO:0040011 313 0.021
macromolecule biosynthetic process GO:0009059 227 0.020
response to carbohydrate GO:0009743 3 0.020
regulation of rna metabolic process GO:0051252 224 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
cell motility GO:0048870 244 0.020
single organism transport GO:0044765 206 0.020
brain development GO:0007420 293 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of transcription dna templated GO:0006355 213 0.020
cilium organization GO:0044782 71 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
nucleic acid templated transcription GO:0097659 181 0.020
positive regulation of secretion GO:0051047 1 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
rna biosynthetic process GO:0032774 181 0.020
system process GO:0003008 185 0.020
regulation of signaling GO:0023051 235 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
organic acid metabolic process GO:0006082 31 0.020
regulation of protein targeting GO:1903533 2 0.019
cell substrate adhesion GO:0031589 4 0.019
transport GO:0006810 220 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of mrna processing GO:0050684 3 0.019
regulation of developmental process GO:0050793 247 0.019
regulation of reproductive process GO:2000241 4 0.019
microtubule based movement GO:0007018 33 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
negative regulation of protein transport GO:0051224 3 0.019
protein import GO:0017038 3 0.019
regulation of gtp catabolic process GO:0033124 2 0.018
response to chemical GO:0042221 320 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
single organism organelle organization GO:1902589 199 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
lateral inhibition GO:0046331 1 0.018
cell matrix adhesion GO:0007160 4 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
endosomal transport GO:0016197 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of response to stimulus GO:0048583 269 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
oxoacid metabolic process GO:0043436 31 0.018
determination of bilateral symmetry GO:0009855 204 0.018
regulation of cell projection assembly GO:0060491 4 0.018
protein localization to plasma membrane GO:0072659 1 0.018
regulation of metal ion transport GO:0010959 4 0.017
startle response GO:0001964 4 0.017
establishment of localization GO:0051234 244 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
regulation of muscle contraction GO:0006937 3 0.017
cellular response to external stimulus GO:0071496 2 0.017
cellular response to nutrient levels GO:0031669 2 0.017
neurotransmitter transport GO:0006836 2 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
regulation of biosynthetic process GO:0009889 250 0.017
atp catabolic process GO:0006200 4 0.017
compound eye development GO:0048749 2 0.017
generation of neurons GO:0048699 385 0.017
head development GO:0060322 303 0.017
meiotic nuclear division GO:0007126 4 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
chordate embryonic development GO:0043009 271 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
single organism nuclear import GO:1902593 3 0.017
phagocytosis GO:0006909 3 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
negative regulation of biological process GO:0048519 304 0.017
negative regulation of kinase activity GO:0033673 4 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
positive regulation of exocytosis GO:0045921 1 0.017
smooth muscle contraction GO:0006939 2 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
nuclear import GO:0051170 3 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
somatic muscle development GO:0007525 4 0.016
localization of cell GO:0051674 244 0.016
regulation of biological quality GO:0065008 263 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
blood vessel development GO:0001568 246 0.016
cellular protein catabolic process GO:0044257 4 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
synaptic vesicle transport GO:0048489 1 0.016
skeletal system development GO:0001501 181 0.016
regulation of protein catabolic process GO:0042176 1 0.016
response to drug GO:0042493 3 0.016
synaptic vesicle localization GO:0097479 1 0.016
golgi vesicle transport GO:0048193 3 0.016
stem cell division GO:0017145 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
primary neural tube formation GO:0014020 1 0.016
amino acid transport GO:0006865 2 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
organelle organization GO:0006996 227 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
response to uv GO:0009411 3 0.016
cellular biosynthetic process GO:0044249 286 0.016
protein complex disassembly GO:0043241 1 0.015
gastrulation GO:0007369 208 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
single organism metabolic process GO:0044710 217 0.015
peptidyl serine modification GO:0018209 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
single organism localization GO:1902578 225 0.015
single fertilization GO:0007338 3 0.015
neuron projection development GO:0031175 180 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
protein dephosphorylation GO:0006470 3 0.015
vasculature development GO:0001944 278 0.015
digestive tract morphogenesis GO:0048546 231 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
regulation of autophagy GO:0010506 3 0.015
carbohydrate homeostasis GO:0033500 1 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
protein polymerization GO:0051258 4 0.015
regulation of protein polymerization GO:0032271 2 0.015
digestive system development GO:0055123 289 0.015
response to hexose GO:0009746 3 0.015
cell migration GO:0016477 237 0.015
regulation of exocytosis GO:0017157 1 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of cell communication GO:0010646 232 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
negative regulation of synapse assembly GO:0051964 2 0.014
cilium morphogenesis GO:0060271 85 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of dendrite development GO:0050773 3 0.014
rna localization GO:0006403 4 0.014
peptide transport GO:0015833 1 0.014
protein acetylation GO:0006473 2 0.014
female sex differentiation GO:0046660 4 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
meiotic cell cycle process GO:1903046 3 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
neuron projection morphogenesis GO:0048812 161 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
chemosensory behavior GO:0007635 1 0.014
actin filament based movement GO:0030048 1 0.014
tube closure GO:0060606 1 0.014
regulation of protein binding GO:0043393 3 0.014
protein metabolic process GO:0019538 183 0.014
melanin metabolic process GO:0006582 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
muscle structure development GO:0061061 196 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
regionalization GO:0003002 274 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
cellular component assembly GO:0022607 170 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
developmental growth GO:0048589 166 0.014
determination of left right symmetry GO:0007368 179 0.014
spermatid development GO:0007286 2 0.014
axonogenesis GO:0007409 152 0.014
regulation of cell shape GO:0008360 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
nuclear migration GO:0007097 3 0.014
membrane invagination GO:0010324 1 0.014
monoamine transport GO:0015844 1 0.014
centrosome organization GO:0051297 1 0.013
cellular localization GO:0051641 97 0.013
cellular component biogenesis GO:0044085 178 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
sensory organ morphogenesis GO:0090596 200 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of cell activation GO:0050865 1 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
glucose homeostasis GO:0042593 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of transporter activity GO:0032409 2 0.013
positive regulation of biological process GO:0048518 253 0.013
cilium assembly GO:0042384 58 0.013
regulation of cell matrix adhesion GO:0001952 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
ear development GO:0043583 127 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
regulation of gene expression GO:0010468 265 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
axon development GO:0061564 166 0.013
regulation of tube size GO:0035150 2 0.013
dicarboxylic acid transport GO:0006835 1 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
adherens junction organization GO:0034332 4 0.013
regulation of signal transduction GO:0009966 225 0.013
actin filament polymerization GO:0030041 2 0.012
membrane fusion GO:0061025 2 0.012
protein secretion GO:0009306 1 0.012
mechanosensory behavior GO:0007638 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
cellular response to radiation GO:0071478 4 0.012
hormone secretion GO:0046879 2 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
macroautophagy GO:0016236 1 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
digestive tract development GO:0048565 265 0.012
interspecies interaction between organisms GO:0044419 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
small molecule metabolic process GO:0044281 77 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of sodium ion transport GO:0002028 2 0.012
regulation of organelle assembly GO:1902115 4 0.012
hormone transport GO:0009914 2 0.012
protein homooligomerization GO:0051260 3 0.012
growth GO:0040007 174 0.012
regulation of blood vessel size GO:0050880 2 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
female gonad development GO:0008585 4 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
response to nutrient GO:0007584 3 0.012
neurotransmitter secretion GO:0007269 2 0.012
response to glucose GO:0009749 3 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
positive regulation of cytokine production GO:0001819 2 0.012
spermatid differentiation GO:0048515 2 0.012
organelle fusion GO:0048284 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
fertilization GO:0009566 3 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
embryonic skeletal system development GO:0048706 97 0.011
negative regulation of secretion GO:0051048 2 0.011
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of jak stat cascade GO:0046425 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
retina development in camera type eye GO:0060041 146 0.011
renal system development GO:0072001 94 0.011
transmembrane transport GO:0055085 120 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
regulation of wound healing GO:0061041 2 0.011
muscle tissue development GO:0060537 110 0.011
regulation of filopodium assembly GO:0051489 2 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of ph GO:0006885 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
neurological system process GO:0050877 62 0.011
epithelial cell differentiation GO:0030855 116 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
liver development GO:0001889 96 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
action potential GO:0001508 19 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
response to alkaloid GO:0043279 2 0.011
protein acylation GO:0043543 3 0.010
post embryonic organ development GO:0048569 4 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
convergent extension GO:0060026 118 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
response to corticosteroid GO:0031960 1 0.010
neuromuscular process controlling balance GO:0050885 3 0.010
negative regulation of cellular process GO:0048523 283 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
lamellipodium organization GO:0097581 1 0.010
peptidyl threonine modification GO:0018210 1 0.010
single organism membrane fusion GO:0044801 2 0.010
sleep GO:0030431 1 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
neuronal action potential GO:0019228 18 0.010
lymphocyte proliferation GO:0046651 1 0.010
cell substrate junction assembly GO:0007044 2 0.010
cell cycle arrest GO:0007050 1 0.010
macromolecule modification GO:0043412 111 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
locomotor rhythm GO:0045475 3 0.010
glial cell migration GO:0008347 3 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
nephron morphogenesis GO:0072028 2 0.010
somatic stem cell maintenance GO:0035019 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
synaptic transmission cholinergic GO:0007271 4 0.010
response to monosaccharide GO:0034284 3 0.010

dyrk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.012
disease of metabolism DOID:0014667 0 0.011