Danio rerio

0 known processes

mpzl2

myelin protein zero-like 2

(Aliases: cb837,eva1,fb07b02,wu:fb07b02)

mpzl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.375
cellular modified amino acid metabolic process GO:0006575 3 0.279
response to stress GO:0006950 263 0.202
locomotion GO:0040011 313 0.160
alpha amino acid metabolic process GO:1901605 3 0.139
cellular aromatic compound metabolic process GO:0006725 295 0.138
regulation of gene expression GO:0010468 265 0.135
cellular nitrogen compound biosynthetic process GO:0044271 218 0.135
cellular amino acid metabolic process GO:0006520 7 0.127
gene expression GO:0010467 252 0.127
regulation of biosynthetic process GO:0009889 250 0.126
heterocycle metabolic process GO:0046483 290 0.120
organic substance biosynthetic process GO:1901576 289 0.119
cellular component movement GO:0006928 335 0.116
heart development GO:0007507 313 0.116
embryo development ending in birth or egg hatching GO:0009792 271 0.116
biosynthetic process GO:0009058 294 0.112
regulation of nitrogen compound metabolic process GO:0051171 251 0.110
cell migration GO:0016477 237 0.108
response to chemical GO:0042221 320 0.099
protein metabolic process GO:0019538 183 0.094
cellular biosynthetic process GO:0044249 286 0.092
cellular macromolecule metabolic process GO:0044260 391 0.091
nucleobase containing compound metabolic process GO:0006139 274 0.090
response to external biotic stimulus GO:0043207 97 0.089
defense response GO:0006952 47 0.088
morphogenesis of an epithelium GO:0002009 333 0.088
organic cyclic compound metabolic process GO:1901360 301 0.087
heterocycle biosynthetic process GO:0018130 215 0.085
response to biotic stimulus GO:0009607 97 0.080
positive regulation of macromolecule metabolic process GO:0010604 93 0.080
defense response to other organism GO:0098542 33 0.078
regulation of sodium ion transport GO:0002028 2 0.076
sensory organ development GO:0007423 393 0.075
regulation of macromolecule biosynthetic process GO:0010556 225 0.075
response to bacterium GO:0009617 58 0.074
aging GO:0007568 2 0.073
regulation of cellular biosynthetic process GO:0031326 245 0.068
rna metabolic process GO:0016070 219 0.064
regulation of developmental process GO:0050793 247 0.064
multi organism process GO:0051704 134 0.064
single organism localization GO:1902578 225 0.061
nucleobase containing compound biosynthetic process GO:0034654 205 0.061
negative regulation of intracellular protein transport GO:0090317 3 0.060
regulation of primary metabolic process GO:0080090 311 0.060
cellular response to chemical stimulus GO:0070887 157 0.060
mitochondrion organization GO:0007005 4 0.060
response to amino acid GO:0043200 2 0.060
brain development GO:0007420 293 0.059
single organism metabolic process GO:0044710 217 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.058
aromatic compound biosynthetic process GO:0019438 217 0.056
organic cyclic compound biosynthetic process GO:1901362 223 0.056
cell motility GO:0048870 244 0.056
regulation of nucleocytoplasmic transport GO:0046822 2 0.055
regulation of response to stimulus GO:0048583 269 0.054
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.054
organonitrogen compound metabolic process GO:1901564 74 0.052
regulation of cytokine production GO:0001817 3 0.052
regulation of molecular function GO:0065009 70 0.052
cell projection organization GO:0030030 284 0.052
regulation of protein localization to nucleus GO:1900180 2 0.049
skeletal system development GO:0001501 181 0.048
nitrogen compound metabolic process GO:0006807 319 0.047
regulation of metabolic process GO:0019222 359 0.046
regulation of biological quality GO:0065008 263 0.046
single organism carbohydrate metabolic process GO:0044723 12 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.045
regulation of multicellular organism growth GO:0040014 4 0.044
s adenosylmethionine metabolic process GO:0046500 1 0.044
localization of cell GO:0051674 244 0.044
regulation of protein import into nucleus GO:0042306 2 0.043
regulation of protein localization to plasma membrane GO:1903076 1 0.043
chordate embryonic development GO:0043009 271 0.042
embryonic skeletal system development GO:0048706 97 0.042
hemopoiesis GO:0030097 183 0.042
Mouse
immune system process GO:0002376 241 0.041
Mouse
embryonic organ development GO:0048568 381 0.041
regulation of protein targeting GO:1903533 2 0.040
neuron differentiation GO:0030182 353 0.038
renal system development GO:0072001 94 0.038
regulation of multicellular organismal process GO:0051239 277 0.038
myeloid cell differentiation GO:0030099 86 0.038
protein localization to nucleus GO:0034504 3 0.038
nucleobase containing small molecule metabolic process GO:0055086 32 0.038
tube morphogenesis GO:0035239 349 0.037
central nervous system development GO:0007417 387 0.037
regulation of metal ion transport GO:0010959 4 0.037
positive regulation of biological process GO:0048518 253 0.036
negative regulation of biological process GO:0048519 304 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
nucleocytoplasmic transport GO:0006913 4 0.036
cellular response to external stimulus GO:0071496 2 0.035
regulation of cytoplasmic transport GO:1903649 4 0.034
neutrophil migration GO:1990266 10 0.034
regulation of heart contraction GO:0008016 32 0.034
cell part morphogenesis GO:0032990 246 0.034
maintenance of location GO:0051235 4 0.034
single organism nuclear import GO:1902593 3 0.034
cellular component morphogenesis GO:0032989 336 0.033
kidney development GO:0001822 92 0.033
cellular component biogenesis GO:0044085 178 0.033
cell surface receptor signaling pathway GO:0007166 325 0.033
response to metal ion GO:0010038 34 0.033
regulation of localization GO:0032879 104 0.033
blood vessel development GO:0001568 246 0.032
cell chemotaxis GO:0060326 17 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
regulation of ion transmembrane transporter activity GO:0032412 2 0.032
regulation of programmed cell death GO:0043067 101 0.032
regulation of signal transduction GO:0009966 225 0.032
transport GO:0006810 220 0.031
neuron development GO:0048666 262 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
negative regulation of cytokine production GO:0001818 1 0.031
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
multicellular organism growth GO:0035264 4 0.030
stem cell differentiation GO:0048863 117 0.030
cell proliferation GO:0008283 80 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
innate immune response GO:0045087 13 0.029
nuclear transport GO:0051169 4 0.029
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.029
behavior GO:0007610 74 0.029
monoamine transport GO:0015844 1 0.028
cellular protein metabolic process GO:0044267 129 0.028
positive regulation of cellular process GO:0048522 201 0.028
establishment of localization GO:0051234 244 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.027
extracellular structure organization GO:0043062 27 0.027
negative regulation of sequestering of calcium ion GO:0051283 4 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
embryonic skeletal system morphogenesis GO:0048704 93 0.027
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.027
regulation of rna metabolic process GO:0051252 224 0.027
immune response GO:0006955 28 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.026
nucleic acid templated transcription GO:0097659 181 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
cellular carbohydrate metabolic process GO:0044262 4 0.025
cellular response to nutrient levels GO:0031669 2 0.025
single organism organelle organization GO:1902589 199 0.025
transcription dna templated GO:0006351 181 0.025
cell projection morphogenesis GO:0048858 244 0.024
epithelial cell differentiation GO:0030855 116 0.024
response to drug GO:0042493 3 0.024
cellular response to stress GO:0033554 62 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
b cell mediated immunity GO:0019724 3 0.024
generation of neurons GO:0048699 385 0.024
intracellular signal transduction GO:0035556 85 0.024
developmental growth GO:0048589 166 0.024
lateral line system development GO:0048925 76 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
protein import into nucleus GO:0006606 3 0.023
nuclear import GO:0051170 3 0.023
cellular amino acid biosynthetic process GO:0008652 2 0.023
regulation of transcription dna templated GO:0006355 213 0.023
response to inorganic substance GO:0010035 38 0.023
response to other organism GO:0051707 97 0.023
embryonic cranial skeleton morphogenesis GO:0048701 90 0.023
cytokinesis GO:0000910 3 0.023
defense response to bacterium GO:0042742 22 0.022
regulation of signaling GO:0023051 235 0.022
multi organism cellular process GO:0044764 2 0.022
oxoacid metabolic process GO:0043436 31 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.022
protein targeting to nucleus GO:0044744 3 0.022
homeostatic process GO:0042592 142 0.021
negative regulation of cellular process GO:0048523 283 0.021
negative chemotaxis GO:0050919 1 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
positive regulation of catabolic process GO:0009896 4 0.021
ion transport GO:0006811 114 0.021
digestive system development GO:0055123 289 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.020
immune system development GO:0002520 191 0.020
Mouse
granulocyte migration GO:0097530 11 0.020
protein localization to plasma membrane GO:0072659 1 0.020
taxis GO:0042330 109 0.020
blood vessel morphogenesis GO:0048514 216 0.020
macromolecule modification GO:0043412 111 0.020
cellular response to starvation GO:0009267 1 0.020
regulation of sequestering of calcium ion GO:0051282 4 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
myeloid leukocyte migration GO:0097529 12 0.019
regulation of protein complex assembly GO:0043254 3 0.019
small molecule metabolic process GO:0044281 77 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.019
cellular response to organic substance GO:0071310 105 0.019
purine containing compound metabolic process GO:0072521 29 0.019
neuron projection development GO:0031175 180 0.019
sphingolipid biosynthetic process GO:0030148 2 0.019
defense response to fungus GO:0050832 2 0.019
inner ear development GO:0048839 126 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
vasculature development GO:0001944 278 0.018
positive regulation of rna biosynthetic process GO:1902680 57 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
neuromast development GO:0048884 46 0.018
positive regulation of transport GO:0051050 2 0.018
rna biosynthetic process GO:0032774 181 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
skin development GO:0043588 54 0.018
ion homeostasis GO:0050801 41 0.018
alcohol biosynthetic process GO:0046165 2 0.017
release of sequestered calcium ion into cytosol GO:0051209 3 0.017
larval development GO:0002164 2 0.017
regulation of response to stress GO:0080134 36 0.017
cation transport GO:0006812 81 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
multicellular organism reproduction GO:0032504 35 0.017
organonitrogen compound biosynthetic process GO:1901566 47 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
regulation of synapse organization GO:0050807 3 0.017
positive regulation of metabolic process GO:0009893 108 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
regulation of ion transport GO:0043269 22 0.016
granulocyte chemotaxis GO:0071621 11 0.016
head development GO:0060322 303 0.016
synaptic vesicle localization GO:0097479 1 0.016
cellular amine metabolic process GO:0044106 2 0.016
heart contraction GO:0060047 71 0.016
fertilization GO:0009566 3 0.016
positive regulation of gene expression GO:0010628 71 0.016
eye development GO:0001654 277 0.016
single organism transport GO:0044765 206 0.016
interaction with host GO:0051701 4 0.016
single organism biosynthetic process GO:0044711 71 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
digestive tract morphogenesis GO:0048546 231 0.015
stem cell maintenance GO:0019827 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
negative regulation of intracellular transport GO:0032387 3 0.015
signal transduction GO:0007165 455 0.015
cellular localization GO:0051641 97 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
protein modification process GO:0036211 100 0.015
regulation of actin filament based movement GO:1903115 1 0.015
nucleic acid metabolic process GO:0090304 244 0.015
regulation of cell activation GO:0050865 1 0.014
syncytium formation GO:0006949 12 0.014
neutrophil chemotaxis GO:0030593 10 0.014
regulation of hydrolase activity GO:0051336 28 0.014
neuroblast fate commitment GO:0014017 1 0.014
extracellular matrix organization GO:0030198 27 0.014
reproduction GO:0000003 40 0.014
negative regulation of immune response GO:0050777 2 0.014
protein polymerization GO:0051258 4 0.014
muscle structure development GO:0061061 196 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
regulation of protein metabolic process GO:0051246 56 0.014
cell death GO:0008219 121 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
cardiac conduction GO:0061337 3 0.014
single organism cellular localization GO:1902580 46 0.014
regulation of catalytic activity GO:0050790 55 0.014
growth GO:0040007 174 0.014
lateral line development GO:0048882 66 0.014
cellular protein modification process GO:0006464 100 0.013
heart morphogenesis GO:0003007 156 0.013
lymphocyte proliferation GO:0046651 1 0.013
regulation of blood circulation GO:1903522 32 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
apoptotic process GO:0006915 116 0.013
organic acid metabolic process GO:0006082 31 0.013
negative regulation of myeloid cell differentiation GO:0045638 1 0.013
urogenital system development GO:0001655 97 0.013
phagocytosis GO:0006909 3 0.013
superoxide metabolic process GO:0006801 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
sequestering of metal ion GO:0051238 3 0.013
response to wounding GO:0009611 116 0.012
gland development GO:0048732 143 0.012
hair cell differentiation GO:0035315 32 0.012
rna 3 end processing GO:0031123 2 0.012
axonogenesis GO:0007409 152 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
chemotaxis GO:0006935 104 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
regulation of blood coagulation GO:0030193 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
striated muscle cell differentiation GO:0051146 129 0.012
mitochondrial transport GO:0006839 2 0.012
hydrogen peroxide metabolic process GO:0042743 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of protein transport GO:0051223 3 0.012
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
b cell activation GO:0042113 2 0.012
cell adhesion GO:0007155 40 0.012
Mouse
cytosolic calcium ion transport GO:0060401 3 0.012
camera type eye development GO:0043010 222 0.011
heart process GO:0003015 71 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
regulation of cell death GO:0010941 103 0.011
autophagy GO:0006914 4 0.011
gtp metabolic process GO:0046039 4 0.011
regulation of transporter activity GO:0032409 2 0.011
digestive tract development GO:0048565 265 0.011
response to carbohydrate GO:0009743 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of innate immune response GO:0045088 11 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
leukocyte chemotaxis GO:0030595 12 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
mononuclear cell proliferation GO:0032943 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of cell communication GO:0010646 232 0.011
response to organic substance GO:0010033 153 0.011
embryonic heart tube development GO:0035050 133 0.011
regulation of cellular component organization GO:0051128 86 0.011
establishment of endothelial barrier GO:0061028 3 0.011
negative regulation of intracellular signal transduction GO:1902532 22 0.011
protein complex assembly GO:0006461 30 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
amine metabolic process GO:0009308 2 0.011
sodium ion transport GO:0006814 24 0.011
immunoglobulin mediated immune response GO:0016064 3 0.010
indole containing compound metabolic process GO:0042430 2 0.010
angiogenesis GO:0001525 158 0.010
cellular response to radiation GO:0071478 4 0.010
negative regulation of kinase activity GO:0033673 4 0.010
cellular component assembly GO:0022607 170 0.010
negative regulation of defense response GO:0031348 2 0.010
response to monosaccharide GO:0034284 3 0.010
metal ion transport GO:0030001 58 0.010
regulation of endopeptidase activity GO:0052548 23 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
zymogen activation GO:0031638 3 0.010
sensory system development GO:0048880 76 0.010

mpzl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
disease of metabolism DOID:0014667 0 0.029
amyloidosis DOID:9120 0 0.029
acquired metabolic disease DOID:0060158 0 0.029
musculoskeletal system disease DOID:17 0 0.020
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014