Danio rerio

27 known processes

p2rx4a

purinergic receptor P2X, ligand-gated ion channel, 4a

(Aliases: wu:fi03f02,p2x4,p2rx4)

p2rx4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transport GO:0051050 2 0.051
lipid storage GO:0019915 1 0.051
larval development GO:0002164 2 0.048
phagocytosis GO:0006909 3 0.044
response to stress GO:0006950 263 0.042
ubiquitin dependent protein catabolic process GO:0006511 3 0.038
modification dependent protein catabolic process GO:0019941 3 0.037
aging GO:0007568 2 0.035
signal transduction GO:0007165 455 0.034
single fertilization GO:0007338 3 0.033
hemopoiesis GO:0030097 183 0.033
immune system development GO:0002520 191 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
establishment of localization GO:0051234 244 0.029
regulation of protein complex assembly GO:0043254 3 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.028
organelle fusion GO:0048284 3 0.027
cellular amine metabolic process GO:0044106 2 0.027
positive regulation of cytokine production GO:0001819 2 0.027
gland development GO:0048732 143 0.027
meiotic nuclear division GO:0007126 4 0.027
determination of bilateral symmetry GO:0009855 204 0.026
regulation of cell activation GO:0050865 1 0.026
specification of symmetry GO:0009799 204 0.026
cellular protein catabolic process GO:0044257 4 0.026
centrosome cycle GO:0007098 1 0.026
response to biotic stimulus GO:0009607 97 0.026
regulation of stem cell differentiation GO:2000736 4 0.025
regulation of binding GO:0051098 3 0.025
organic acid metabolic process GO:0006082 31 0.025
maintenance of location GO:0051235 4 0.025
adult behavior GO:0030534 2 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
single organism transport GO:0044765 206 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
amine metabolic process GO:0009308 2 0.025
single organism membrane fusion GO:0044801 2 0.025
positive regulation of cell activation GO:0050867 1 0.024
regulation of cytokine production GO:0001817 3 0.024
stem cell proliferation GO:0072089 4 0.024
immune system process GO:0002376 241 0.024
synaptic vesicle transport GO:0048489 1 0.024
response to carbohydrate GO:0009743 3 0.024
regulation of reproductive process GO:2000241 4 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
centrosome organization GO:0051297 1 0.024
establishment of synaptic vesicle localization GO:0097480 1 0.023
membrane fusion GO:0061025 2 0.022
embryonic organ development GO:0048568 381 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
response to topologically incorrect protein GO:0035966 2 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
multicellular organism growth GO:0035264 4 0.022
single organism metabolic process GO:0044710 217 0.022
protein polyubiquitination GO:0000209 4 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
synaptic vesicle localization GO:0097479 1 0.021
response to nutrient GO:0007584 3 0.021
gtp metabolic process GO:0046039 4 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
hepaticobiliary system development GO:0061008 98 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
organonitrogen compound metabolic process GO:1901564 74 0.020
gtp catabolic process GO:0006184 2 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
liver development GO:0001889 96 0.020
spindle assembly GO:0051225 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
regulation of synapse organization GO:0050807 3 0.020
response to chemical GO:0042221 320 0.020
microtubule organizing center organization GO:0031023 1 0.020
response to hexose GO:0009746 3 0.019
positive regulation of secretion GO:0051047 1 0.019
cellular ketone metabolic process GO:0042180 11 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
protein import GO:0017038 3 0.019
response to monosaccharide GO:0034284 3 0.019
xenobiotic metabolic process GO:0006805 4 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
negative regulation of biological process GO:0048519 304 0.019
cellular response to external stimulus GO:0071496 2 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
amino acid transport GO:0006865 2 0.018
mitochondrion organization GO:0007005 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
positive regulation of catabolic process GO:0009896 4 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of signaling GO:0023051 235 0.018
determination of left right symmetry GO:0007368 179 0.018
cellular transition metal ion homeostasis GO:0046916 3 0.018
internal protein amino acid acetylation GO:0006475 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.018
stem cell maintenance GO:0019827 4 0.018
leukocyte proliferation GO:0070661 1 0.018
nuclear transport GO:0051169 4 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
single organism nuclear import GO:1902593 3 0.017
cellular component movement GO:0006928 335 0.017
response to organic substance GO:0010033 153 0.017
oxoacid metabolic process GO:0043436 31 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
small molecule metabolic process GO:0044281 77 0.017
cilium morphogenesis GO:0060271 85 0.017
b cell activation GO:0042113 2 0.017
response to glucose GO:0009749 3 0.017
transport GO:0006810 220 0.017
regulation of metal ion transport GO:0010959 4 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of response to stimulus GO:0048583 269 0.017
fertilization GO:0009566 3 0.017
regulation of synapse assembly GO:0051963 3 0.016
entrainment of circadian clock GO:0009649 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of gtpase activity GO:0043087 2 0.016
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.016
tissue remodeling GO:0048771 4 0.016
rna localization GO:0006403 4 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
single organism localization GO:1902578 225 0.016
response to external biotic stimulus GO:0043207 97 0.016
negative regulation of protein complex assembly GO:0031333 1 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
meiotic cell cycle process GO:1903046 3 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
calcium ion import GO:0070509 4 0.016
negative regulation of nuclear division GO:0051784 3 0.016
protein localization to nucleus GO:0034504 3 0.015
response to glucocorticoid GO:0051384 1 0.015
lipid catabolic process GO:0016042 4 0.015
cellular response to unfolded protein GO:0034620 2 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of biological quality GO:0065008 263 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
cellular response to nutrient levels GO:0031669 2 0.015
protein localization to plasma membrane GO:0072659 1 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
protein metabolic process GO:0019538 183 0.015
golgi vesicle transport GO:0048193 3 0.015
nuclear import GO:0051170 3 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
ion transport GO:0006811 114 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
glucose homeostasis GO:0042593 1 0.015
er nucleus signaling pathway GO:0006984 2 0.015
endosomal transport GO:0016197 2 0.015
atp catabolic process GO:0006200 4 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
germ line stem cell maintenance GO:0030718 2 0.015
carbohydrate homeostasis GO:0033500 1 0.015
organic substance biosynthetic process GO:1901576 289 0.015
protein polymerization GO:0051258 4 0.015
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.015
lymphocyte proliferation GO:0046651 1 0.014
response to drug GO:0042493 3 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
antimicrobial humoral response GO:0019730 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
heterocycle metabolic process GO:0046483 290 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
endoplasmic reticulum unfolded protein response GO:0030968 2 0.014
exocytosis GO:0006887 1 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
regulation of signal transduction GO:0009966 225 0.014
heart development GO:0007507 313 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of intracellular ph GO:0051453 1 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
mononuclear cell proliferation GO:0032943 1 0.014
positive regulation of lipid metabolic process GO:0045834 1 0.014
regulation of growth rate GO:0040009 1 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of hormone secretion GO:0046883 2 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
positive regulation of cell cycle GO:0045787 3 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
protein targeting to nucleus GO:0044744 3 0.013
recombinational repair GO:0000725 1 0.013
peptidyl serine modification GO:0018209 2 0.013
cilium organization GO:0044782 71 0.013
cellular response to starvation GO:0009267 1 0.013
protein secretion GO:0009306 1 0.013
catechol containing compound metabolic process GO:0009712 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of primary metabolic process GO:0080090 311 0.013
cellular protein metabolic process GO:0044267 129 0.013
positive regulation of cellular process GO:0048522 201 0.013
actin filament based movement GO:0030048 1 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
peptide transport GO:0015833 1 0.013
regulation of ph GO:0006885 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
homeostatic process GO:0042592 142 0.013
camera type eye development GO:0043010 222 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
response to unfolded protein GO:0006986 2 0.013
regulation of cell projection assembly GO:0060491 4 0.013
somatic muscle development GO:0007525 4 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
response to corticosteroid GO:0031960 1 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
digestive system development GO:0055123 289 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
protein stabilization GO:0050821 2 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
macromolecule modification GO:0043412 111 0.012
glial cell migration GO:0008347 3 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
compound eye development GO:0048749 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
cell cycle arrest GO:0007050 1 0.012
response to endogenous stimulus GO:0009719 83 0.012
system process GO:0003008 185 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
phosphorus metabolic process GO:0006793 109 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
viral process GO:0016032 1 0.012
cellular component disassembly GO:0022411 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
regulation of developmental process GO:0050793 247 0.012
positive regulation of reproductive process GO:2000243 2 0.012
meiotic chromosome segregation GO:0045132 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cellular response to light stimulus GO:0071482 4 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
forebrain cell migration GO:0021885 1 0.012
toxin metabolic process GO:0009404 1 0.012
cytokinesis GO:0000910 3 0.012
synaptic vesicle endocytosis GO:0048488 1 0.012
negative regulation of reproductive process GO:2000242 3 0.012
response to vitamin GO:0033273 3 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.011
hormone transport GO:0009914 2 0.011
locomotion GO:0040011 313 0.011
regulation of protein polymerization GO:0032271 2 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
neuroblast proliferation GO:0007405 2 0.011
response to uv GO:0009411 3 0.011
apoptotic process involved in development GO:1902742 2 0.011
regulation of protein transport GO:0051223 3 0.011
peptidyl threonine modification GO:0018210 1 0.011
regulation of cell shape GO:0008360 1 0.011
protein acetylation GO:0006473 2 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
diterpenoid metabolic process GO:0016101 15 0.011
cellular component morphogenesis GO:0032989 336 0.011
type b pancreatic cell development GO:0003323 4 0.011
female sex differentiation GO:0046660 4 0.011
organism emergence from protective structure GO:0071684 4 0.011
membrane lipid biosynthetic process GO:0046467 2 0.011
regulation of protein binding GO:0043393 3 0.011
cognition GO:0050890 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
sensory perception of smell GO:0007608 2 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of blood pressure GO:0008217 1 0.011
biosynthetic process GO:0009058 294 0.011
cell cell recognition GO:0009988 1 0.011
regulation of metabolic process GO:0019222 359 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
dicarboxylic acid transport GO:0006835 1 0.011
phagocytosis engulfment GO:0006911 1 0.011
protein homooligomerization GO:0051260 3 0.011
translational initiation GO:0006413 3 0.011
positive regulation of multi organism process GO:0043902 3 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
protein acylation GO:0043543 3 0.011
organelle organization GO:0006996 227 0.011
regulation of calcium ion transport GO:0051924 2 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
organic cyclic compound metabolic process GO:1901360 301 0.010
b cell differentiation GO:0030183 1 0.010
neurotransmitter secretion GO:0007269 2 0.010
regulation of protein targeting GO:1903533 2 0.010
tube closure GO:0060606 1 0.010
single organism organelle organization GO:1902589 199 0.010
synaptic vesicle recycling GO:0036465 1 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
killing of cells of other organism GO:0031640 1 0.010
hormone secretion GO:0046879 2 0.010
multi organism process GO:0051704 134 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
regulation of jun kinase activity GO:0043506 3 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
ovulation cycle GO:0042698 2 0.010
regulation of muscle contraction GO:0006937 3 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
kidney development GO:0001822 92 0.010
eye development GO:0001654 277 0.010
death GO:0016265 121 0.010
cellular response to topologically incorrect protein GO:0035967 2 0.010
response to other organism GO:0051707 97 0.010
membrane invagination GO:0010324 1 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
muscle structure development GO:0061061 196 0.010
regulation of transporter activity GO:0032409 2 0.010
stem cell division GO:0017145 1 0.010
cell morphogenesis GO:0000902 289 0.010
cell proliferation GO:0008283 80 0.010
actin filament polymerization GO:0030041 2 0.010

p2rx4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.022
lysosomal storage disease DOID:3211 0 0.019
inherited metabolic disorder DOID:655 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.013