Danio rerio

0 known processes

sgpl1

sphingosine-1-phosphate lyase 1

(Aliases: zgc:162153)

sgpl1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
maintenance of location GO:0051235 4 0.347
biosynthetic process GO:0009058 294 0.255
regulation of biosynthetic process GO:0009889 250 0.238
regulation of innate immune response GO:0045088 11 0.227
response to ketone GO:1901654 1 0.208
triglyceride homeostasis GO:0070328 2 0.199
lipid homeostasis GO:0055088 3 0.189
regulation of fatty acid metabolic process GO:0019217 1 0.159
larval development GO:0002164 2 0.156
regulation of metabolic process GO:0019222 359 0.139
lipid storage GO:0019915 1 0.136
aromatic compound biosynthetic process GO:0019438 217 0.124
regulation of gene expression GO:0010468 265 0.123
regulation of transcription dna templated GO:0006355 213 0.122
small molecule metabolic process GO:0044281 77 0.118
heterocycle metabolic process GO:0046483 290 0.109
immune system process GO:0002376 241 0.108
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.103
cellular response to lipopolysaccharide GO:0071222 3 0.102
response to chemical GO:0042221 320 0.102
organic cyclic compound metabolic process GO:1901360 301 0.101
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.099
gene expression GO:0010467 252 0.095
regulation of cellular biosynthetic process GO:0031326 245 0.094
organic substance biosynthetic process GO:1901576 289 0.094
aging GO:0007568 2 0.094
signal transduction GO:0007165 455 0.091
Mouse
cellular response to lipid GO:0071396 39 0.090
nucleobase containing compound metabolic process GO:0006139 274 0.089
nitrogen compound metabolic process GO:0006807 319 0.089
Mouse
response to alkaloid GO:0043279 2 0.089
regulation of macromolecule metabolic process GO:0060255 317 0.088
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.086
regulation of cellular metabolic process GO:0031323 320 0.085
gtp metabolic process GO:0046039 4 0.084
single organism metabolic process GO:0044710 217 0.082
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.081
response to steroid hormone GO:0048545 35 0.081
guanosine containing compound catabolic process GO:1901069 2 0.081
response to stress GO:0006950 263 0.081
rna biosynthetic process GO:0032774 181 0.079
cellular ketone metabolic process GO:0042180 11 0.079
regulation of macromolecule biosynthetic process GO:0010556 225 0.077
proteolysis GO:0006508 38 0.077
programmed cell death GO:0012501 119 0.076
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.076
regulation of inflammatory response GO:0050727 2 0.076
regulation of primary metabolic process GO:0080090 311 0.072
cell migration GO:0016477 237 0.071
Mouse
cellular response to biotic stimulus GO:0071216 3 0.071
positive regulation of transport GO:0051050 2 0.070
regulation of biological quality GO:0065008 263 0.068
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.067
positive regulation of cellular process GO:0048522 201 0.067
regulation of response to stimulus GO:0048583 269 0.065
guanosine containing compound metabolic process GO:1901068 4 0.064
cellular macromolecule metabolic process GO:0044260 391 0.063
macromolecule biosynthetic process GO:0009059 227 0.063
protein import into nucleus GO:0006606 3 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.061
nucleic acid metabolic process GO:0090304 244 0.060
multicellular organism growth GO:0035264 4 0.059
Mouse
heterocycle biosynthetic process GO:0018130 215 0.059
acylglycerol homeostasis GO:0055090 2 0.059
nucleobase containing compound biosynthetic process GO:0034654 205 0.058
response to other organism GO:0051707 97 0.058
transcription dna templated GO:0006351 181 0.057
regulation of cell communication GO:0010646 232 0.056
apoptotic process GO:0006915 116 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
regulation of protein transport GO:0051223 3 0.055
carboxylic acid metabolic process GO:0019752 22 0.055
cellular response to chemical stimulus GO:0070887 157 0.054
protein localization to nucleus GO:0034504 3 0.054
adult behavior GO:0030534 2 0.053
response to external biotic stimulus GO:0043207 97 0.052
response to wounding GO:0009611 116 0.052
system process GO:0003008 185 0.050
cellular macromolecule biosynthetic process GO:0034645 224 0.050
regulation of rna biosynthetic process GO:2001141 213 0.049
localization of cell GO:0051674 244 0.049
Mouse
regulation of rna metabolic process GO:0051252 224 0.048
organic cyclic compound biosynthetic process GO:1901362 223 0.048
gtp catabolic process GO:0006184 2 0.048
transport GO:0006810 220 0.048
transmembrane transport GO:0055085 120 0.047
nucleocytoplasmic transport GO:0006913 4 0.047
regulation of tube size GO:0035150 2 0.047
response to lipid GO:0033993 60 0.047
regulation of signal transduction GO:0009966 225 0.047
response to external stimulus GO:0009605 264 0.046
i kappab kinase nf kappab signaling GO:0007249 4 0.046
rna metabolic process GO:0016070 219 0.046
nucleic acid templated transcription GO:0097659 181 0.046
cognition GO:0050890 1 0.046
organelle organization GO:0006996 227 0.045
positive regulation of gtp catabolic process GO:0033126 1 0.045
cellular biosynthetic process GO:0044249 286 0.044
negative regulation of biological process GO:0048519 304 0.044
locomotion GO:0040011 313 0.043
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.043
cellular response to external stimulus GO:0071496 2 0.043
regulation of cellular ketone metabolic process GO:0010565 7 0.043
homeostatic process GO:0042592 142 0.043
single organism localization GO:1902578 225 0.043
fatty acid biosynthetic process GO:0006633 4 0.042
protein metabolic process GO:0019538 183 0.042
negative regulation of defense response GO:0031348 2 0.042
organic acid metabolic process GO:0006082 31 0.042
head development GO:0060322 303 0.041
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.040
heart development GO:0007507 313 0.039
protein targeting to nucleus GO:0044744 3 0.039
cell motility GO:0048870 244 0.039
Mouse
cellular lipid metabolic process GO:0044255 36 0.039
protein import GO:0017038 3 0.038
phosphorus metabolic process GO:0006793 109 0.038
positive regulation of biological process GO:0048518 253 0.038
defense response GO:0006952 47 0.038
negative regulation of cellular process GO:0048523 283 0.037
xenobiotic metabolic process GO:0006805 4 0.037
response to hormone GO:0009725 48 0.036
positive regulation of catabolic process GO:0009896 4 0.035
regulation of establishment of protein localization GO:0070201 4 0.034
long chain fatty acid metabolic process GO:0001676 1 0.034
lipid catabolic process GO:0016042 4 0.034
positive regulation of blood circulation GO:1903524 2 0.033
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.033
lipid oxidation GO:0034440 1 0.033
alcohol biosynthetic process GO:0046165 2 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
amine metabolic process GO:0009308 2 0.032
carboxylic acid catabolic process GO:0046395 3 0.032
cell surface receptor signaling pathway GO:0007166 325 0.032
Mouse
cellular component movement GO:0006928 335 0.032
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.032
digestive system development GO:0055123 289 0.032
regulation of purine nucleotide catabolic process GO:0033121 2 0.032
regulation of signaling GO:0023051 235 0.032
inflammatory response GO:0006954 8 0.032
mitochondrion organization GO:0007005 4 0.032
regulation of hydrolase activity GO:0051336 28 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
single organism nuclear import GO:1902593 3 0.031
regulation of protein targeting GO:1903533 2 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
positive regulation of nucleotide catabolic process GO:0030813 1 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
response to endogenous stimulus GO:0009719 83 0.031
cellular response to hormone stimulus GO:0032870 39 0.031
response to drug GO:0042493 3 0.031
phagocytosis GO:0006909 3 0.031
establishment of localization GO:0051234 244 0.031
cellular localization GO:0051641 97 0.031
positive regulation of defense response GO:0031349 9 0.030
intracellular signal transduction GO:0035556 85 0.030
multicellular organismal metabolic process GO:0044236 2 0.030
nuclear import GO:0051170 3 0.030
response to bacterium GO:0009617 58 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
organelle fusion GO:0048284 3 0.029
sequestering of metal ion GO:0051238 3 0.029
response to nutrient GO:0007584 3 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
response to xenobiotic stimulus GO:0009410 45 0.029
regulation of behavior GO:0050795 24 0.029
regulation of gtp catabolic process GO:0033124 2 0.029
nuclear transport GO:0051169 4 0.028
g protein coupled receptor signaling pathway GO:0007186 74 0.028
ion homeostasis GO:0050801 41 0.028
cellular amine metabolic process GO:0044106 2 0.028
calcium ion transport into cytosol GO:0060402 3 0.028
regulation of nucleoside metabolic process GO:0009118 2 0.028
chemical homeostasis GO:0048878 49 0.028
death GO:0016265 121 0.027
cytosolic calcium ion transport GO:0060401 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
cellular response to steroid hormone stimulus GO:0071383 31 0.027
positive regulation of macromolecule metabolic process GO:0010604 93 0.027
vasculature development GO:0001944 278 0.027
Mouse
regulation of binding GO:0051098 3 0.027
negative regulation of protein transport GO:0051224 3 0.027
collagen metabolic process GO:0032963 2 0.027
tube morphogenesis GO:0035239 349 0.027
chemotaxis GO:0006935 104 0.027
positive regulation of secretion by cell GO:1903532 1 0.027
regulation of sequestering of calcium ion GO:0051282 4 0.026
single organism transport GO:0044765 206 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.026
fertilization GO:0009566 3 0.026
single organism biosynthetic process GO:0044711 71 0.026
neutrophil migration GO:1990266 10 0.026
positive regulation of secretion GO:0051047 1 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
regulation of cell activation GO:0050865 1 0.026
sensory perception of chemical stimulus GO:0007606 3 0.026
blood vessel morphogenesis GO:0048514 216 0.025
Mouse
positive regulation of immune effector process GO:0002699 3 0.025
negative regulation of secretion GO:0051048 2 0.025
immune response GO:0006955 28 0.025
response to vitamin GO:0033273 3 0.025
fat soluble vitamin metabolic process GO:0006775 4 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
regulation of cytokine production GO:0001817 3 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.025
response to organic substance GO:0010033 153 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
cellular response to organic substance GO:0071310 105 0.025
protein localization to plasma membrane GO:0072659 1 0.024
establishment of protein localization to plasma membrane GO:0090002 1 0.024
negative regulation of programmed cell death GO:0043069 58 0.024
regulation of gtpase activity GO:0043087 2 0.024
lipid metabolic process GO:0006629 52 0.024
Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.024
purine nucleotide metabolic process GO:0006163 27 0.024
negative regulation of response to stimulus GO:0048585 104 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
Mouse
regulation of developmental process GO:0050793 247 0.023
Mouse
oxoacid metabolic process GO:0043436 31 0.023
negative regulation of secretion by cell GO:1903531 2 0.023
peptide metabolic process GO:0006518 1 0.023
sequestering of calcium ion GO:0051208 3 0.023
protein secretion GO:0009306 1 0.023
regulation of programmed cell death GO:0043067 101 0.023
brain development GO:0007420 293 0.023
endosomal transport GO:0016197 2 0.023
multi organism process GO:0051704 134 0.023
Mouse
regulation of blood vessel size GO:0050880 2 0.023
cellular response to molecule of bacterial origin GO:0071219 3 0.023
cytokinesis GO:0000910 3 0.022
multicellular organismal macromolecule metabolic process GO:0044259 2 0.022
cell death GO:0008219 121 0.022
lipid localization GO:0010876 11 0.022
blood vessel development GO:0001568 246 0.022
Mouse
neuron differentiation GO:0030182 353 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
positive regulation of cytokine production GO:0001819 2 0.022
innate immune response GO:0045087 13 0.022
apoptotic signaling pathway GO:0097190 23 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
ion transmembrane transport GO:0034220 91 0.022
cell migration involved in gastrulation GO:0042074 79 0.021
single organism membrane fusion GO:0044801 2 0.021
regulation of homeostatic process GO:0032844 9 0.021
wound healing GO:0042060 90 0.021
monocarboxylic acid catabolic process GO:0072329 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
monocarboxylic acid biosynthetic process GO:0072330 12 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
regulation of blood pressure GO:0008217 1 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
monocarboxylic acid metabolic process GO:0032787 17 0.021
positive regulation of lipid metabolic process GO:0045834 1 0.020
organic hydroxy compound transport GO:0015850 14 0.020
cellular protein metabolic process GO:0044267 129 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.020
epithelial cell differentiation GO:0030855 116 0.020
regulation of molecular function GO:0065009 70 0.020
regulation of endopeptidase activity GO:0052548 23 0.020
regulation of apoptotic process GO:0042981 98 0.020
embryonic organ development GO:0048568 381 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
neuron development GO:0048666 262 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
negative regulation of metabolic process GO:0009892 86 0.020
response to organic cyclic compound GO:0014070 51 0.020
intracellular receptor signaling pathway GO:0030522 30 0.020
organic acid catabolic process GO:0016054 3 0.020
cellular protein modification process GO:0006464 100 0.020
toll like receptor signaling pathway GO:0002224 4 0.019
regulation of cell death GO:0010941 103 0.019
digestive tract development GO:0048565 265 0.019
cellular response to xenobiotic stimulus GO:0071466 35 0.019
smooth muscle contraction GO:0006939 2 0.019
cellular response to nutrient levels GO:0031669 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
negative regulation of cytokine production GO:0001818 1 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
small molecule catabolic process GO:0044282 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
regulation of sterol transport GO:0032371 3 0.019
nucleoside phosphate metabolic process GO:0006753 28 0.019
cellular response to endogenous stimulus GO:0071495 68 0.018
neuroblast proliferation GO:0007405 2 0.018
autophagy GO:0006914 4 0.018
release of sequestered calcium ion into cytosol GO:0051209 3 0.018
taxis GO:0042330 109 0.018
regulation of hormone secretion GO:0046883 2 0.018
angiogenesis GO:0001525 158 0.018
positive regulation of inflammatory response GO:0050729 1 0.018
digestive system process GO:0022600 9 0.018
cellular lipid catabolic process GO:0044242 3 0.018
digestion GO:0007586 11 0.018
antimicrobial humoral response GO:0019730 2 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
peptide transport GO:0015833 1 0.017
cellular component biogenesis GO:0044085 178 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
central nervous system development GO:0007417 387 0.017
response to hexose GO:0009746 3 0.017
response to biotic stimulus GO:0009607 97 0.017
hindbrain development GO:0030902 91 0.017
retina development in camera type eye GO:0060041 146 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
rna localization GO:0006403 4 0.017
negative regulation of mapk cascade GO:0043409 4 0.017
cellular response to stress GO:0033554 62 0.017
positive regulation of cell activation GO:0050867 1 0.017
negative regulation of cell death GO:0060548 60 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
organic substance transport GO:0071702 58 0.017
regulation of lipase activity GO:0060191 2 0.017
protein polymerization GO:0051258 4 0.017
membrane fusion GO:0061025 2 0.017
regulation of metal ion transport GO:0010959 4 0.017
cellular amide metabolic process GO:0043603 4 0.016
meiotic nuclear division GO:0007126 4 0.016
multicellular organismal response to stress GO:0033555 2 0.016
positive regulation of catalytic activity GO:0043085 25 0.016
positive regulation of gene expression GO:0010628 71 0.016
organophosphate metabolic process GO:0019637 37 0.016
regulation of protein complex assembly GO:0043254 3 0.016
small molecule biosynthetic process GO:0044283 16 0.016
positive regulation of leukocyte mediated immunity GO:0002705 1 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
neutrophil chemotaxis GO:0030593 10 0.016
hepaticobiliary system development GO:0061008 98 0.016
peptidyl serine modification GO:0018209 2 0.016
stem cell maintenance GO:0019827 4 0.016
gastrulation GO:0007369 208 0.016
positive regulation of metabolic process GO:0009893 108 0.016
cell substrate adhesion GO:0031589 4 0.016
interspecies interaction between organisms GO:0044419 4 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
inorganic ion transmembrane transport GO:0098660 57 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
regulation of lipid transport GO:0032368 4 0.016
positive regulation of transcription dna templated GO:0045893 57 0.016
single organism organelle organization GO:1902589 199 0.015
actomyosin structure organization GO:0031032 53 0.015
b cell activation GO:0042113 2 0.015
positive regulation of neuron apoptotic process GO:0043525 1 0.015
exocytosis GO:0006887 1 0.015
muscle cell differentiation GO:0042692 139 0.015
lipid biosynthetic process GO:0008610 22 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
regulation of protein binding GO:0043393 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of cellular component organization GO:0051128 86 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
hormone transport GO:0009914 2 0.015
sensory organ development GO:0007423 393 0.015
generation of neurons GO:0048699 385 0.015
response to glucose GO:0009749 3 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
regulation of epidermis development GO:0045682 2 0.015
secondary metabolic process GO:0019748 3 0.015
golgi vesicle transport GO:0048193 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
embryonic heart tube development GO:0035050 133 0.014
compound eye development GO:0048749 2 0.014
cell proliferation GO:0008283 80 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of multicellular organismal metabolic process GO:0044246 2 0.014
response to carbohydrate GO:0009743 3 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
regulation of dna replication GO:0006275 3 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of protein maturation GO:1903317 10 0.014
organic acid biosynthetic process GO:0016053 12 0.014
macromolecule localization GO:0033036 54 0.014
specification of symmetry GO:0009799 204 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
leukocyte mediated cytotoxicity GO:0001909 1 0.014
regulation of reproductive process GO:2000241 4 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
regulation of defense response GO:0031347 14 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
ion transport GO:0006811 114 0.014
sleep GO:0030431 1 0.014
energy reserve metabolic process GO:0006112 2 0.014
regulation of transporter activity GO:0032409 2 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
Mouse
stem cell division GO:0017145 1 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
inorganic anion transport GO:0015698 25 0.014
cytoskeleton organization GO:0007010 96 0.014
small gtpase mediated signal transduction GO:0007264 8 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
regulation of positive chemotaxis GO:0050926 4 0.013
steroid hormone mediated signaling pathway GO:0043401 9 0.013
cellular divalent inorganic cation homeostasis GO:0072503 13 0.013
determination of left right symmetry GO:0007368 179 0.013
determination of bilateral symmetry GO:0009855 204 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
cation transport GO:0006812 81 0.013
eye development GO:0001654 277 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
regulation of cholesterol transport GO:0032374 3 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
meiotic cell cycle process GO:1903046 3 0.013
cellular response to starvation GO:0009267 1 0.013
purine ribonucleotide metabolic process GO:0009150 27 0.013
circadian sleep wake cycle GO:0042745 2 0.013
organelle assembly GO:0070925 110 0.013
phagocytosis engulfment GO:0006911 1 0.013
response to amphetamine GO:0001975 1 0.013
regulation of ph GO:0006885 3 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
liver development GO:0001889 96 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
spermatid development GO:0007286 2 0.012
fatty acid transport GO:0015908 1 0.012
positive regulation of signal transduction GO:0009967 56 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
fatty acid catabolic process GO:0009062 1 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
cation homeostasis GO:0055080 33 0.012
response to molecule of bacterial origin GO:0002237 14 0.012
positive regulation of cell communication GO:0010647 56 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
positive regulation of hydrolase activity GO:0051345 13 0.012
stem cell differentiation GO:0048863 117 0.012
gland development GO:0048732 143 0.012
protein complex disassembly GO:0043241 1 0.012
response to abiotic stimulus GO:0009628 122 0.012
establishment of localization in cell GO:0051649 77 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
neurological system process GO:0050877 62 0.012
hatching GO:0035188 4 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
protein modification process GO:0036211 100 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
neurotransmitter secretion GO:0007269 2 0.012
hormone secretion GO:0046879 2 0.012
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.012
single fertilization GO:0007338 3 0.012
digestive tract morphogenesis GO:0048546 231 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
positive regulation of cell division GO:0051781 2 0.011
response to hydrogen peroxide GO:0042542 3 0.011
granulocyte migration GO:0097530 11 0.011
regulation of wound healing GO:0061041 2 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
neural crest cell development GO:0014032 62 0.011
collagen biosynthetic process GO:0032964 2 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
striated muscle cell development GO:0055002 108 0.011
membrane invagination GO:0010324 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
Mouse
atp catabolic process GO:0006200 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
negative regulation of multi organism process GO:0043901 3 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of collagen metabolic process GO:0010712 2 0.011
stem cell proliferation GO:0072089 4 0.011
muscle cell development GO:0055001 115 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
regulation of response to external stimulus GO:0032101 31 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of lipase activity GO:0060193 1 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
fatty acid oxidation GO:0019395 1 0.011
regulation of protein metabolic process GO:0051246 56 0.011
calcium ion import GO:0070509 4 0.011
neural crest cell differentiation GO:0014033 72 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011

sgpl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.050
sensory system disease DOID:0050155 0 0.026
eye and adnexa disease DOID:1492 0 0.026
eye disease DOID:5614 0 0.026
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.013